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2014 Journal Article Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotypeWhitehall, V. L. J., Dumenil, T. D., McKeone, D. M., Bond, C. E., Bettington, M. L., Buttenshaw, R. L., Bowdler, L., Montgomery, G. W., Wockner, L. F. and Leggett, B. A. (2014). Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype. Epigenetics, 9 (11), 1454-1460. doi: 10.4161/15592294.2014.971624 |
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2014 Journal Article Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissueDumenil, Troy D., Wockner, Leesa F., Bettington, Mark, Mckeone, Diane M., Klein, Kerenaftali, Bowdler, Lisa M., Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L. J. (2014). Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue. Genes Chromosomes and Cancer, 53 (7), 537-548. doi: 10.1002/gcc.22164 |
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2014 Journal Article Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instabilityBond, Catherine E., Nancarrow, Derek J., Wockner, Leesa F., Wallace, Leanne, Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L. J. (2014). Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability. Plos One, 9 (3) e91739, e91739. doi: 10.1371/journal.pone.0091739 |
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2014 Journal Article Critical appraisal of the diagnosis of the sessile serrated adenomaBettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Wockner, Leesa, Whitehall, Vicki and Leggett, Barbara (2014). Critical appraisal of the diagnosis of the sessile serrated adenoma. American Journal of Surgical Pathology, 38 (2), 158-166. doi: 10.1097/PAS.0000000000000103 |
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2013 Journal Article PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in Colorectal cancerDay, Fiona L., Jorissen, Robert N., Lipton, Lara, Mouradov, Dmitri, Sakthianandeswaren, Anuratha, Christie, Michael, Li, Shan, Tsui, Cary, Tie, Jeannie, Desai, Jayesh, Xu, Zheng-Zhou, Molloy, Peter, Whitehall, Vicki, Leggett, Barbara A., Jones, Ian T., McLaughlin, Stephen, Ward, Robyn L., Hawkins, Nicholas J., Ruszkiewicz, Andrew R., Moore, James, Busam, Dana, Zhao, Qi, Strausberg, Robert L., Gibbs, Peter and Sieber, Oliver M. (2013). PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in Colorectal cancer. Clinical Cancer Research, 19 (12), 3285-3296. doi: 10.1158/1078-0432.CCR-12-3614 |
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2013 Journal Article Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical managementRosty, Christophe, Hewett, David G., Brown, Ian S., Leggett, Barbara A. and Whitehall, Vicki L. J. (2013). Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management. Journal of Gastroenterology, 48 (3), 287-302. doi: 10.1007/s00535-012-0720-y |
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2013 Journal Article The serrated pathway to colorectal carcinoma: current concepts and challengesBettington, Mark, Walker, Neal, Clouston, Andrew, Brown, Ian, Leggett, Barbara and Whitehall, Vicki (2013). The serrated pathway to colorectal carcinoma: current concepts and challenges. Histopathology, 62 (3), 367-386. doi: 10.1111/his.12055 |
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2012 Journal Article Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancersBond, Catherine E., Umapathy, Aarti, Buttenshaw, Ron L., Wockner, Leesa, Leggett, Barbara A. and Whitehall, Vicki L. J. (2012). Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers. Plos One, 7 (10) e47483, e47483.1-e47483.9. doi: 10.1371/journal.pone.0047483 |
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2012 Journal Article Oncogenic PIK3CA mutations in colorectal cancers and polypsWhitehall, Vicki L. J., Rickman, Celestine, Bond, Catherine E., Ramsnes, Ingunn, Greco, Sonia A., Umapathy, Aarti, McKeone, Diane, Faleiro, Rebecca J., Buttenshaw, Ron L., Worthley, Daniel L., Nayler, Sam, Zhao, Zhen Zhen, Montgomery, Grant W., Mallitt, Kylie-Ann, Jass, Jeremy R., Matsubara, Nagahide, Notohara, Kenji, Ishii, Tatsuhiro and Leggett, Barbara A. (2012). Oncogenic PIK3CA mutations in colorectal cancers and polyps. International Journal of Cancer, 131 (4), 813-820. doi: 10.1002/ijc.26440 |
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2011 Journal Article Microsatellite instability: Detection and management in sporadic colorectal cancerWhitehall, Vicki and Leggett, Barbara (2011). Microsatellite instability: Detection and management in sporadic colorectal cancer. Journal of Gastroenterology and Hepatology, 26 (12), 1697-1699. doi: 10.1111/j.1440-1746.2011.06932.x |
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2011 Journal Article Numerical ecology validates a biogeographical distribution and gender-based effect on mucosa-associated bacteria along the human colonde Carcer, Daniel Aguirre, Ó Cuív, Páraic, Wang, Tingting, Kang, Seungha, Worthley, Daniel, Whitehall, Vicki, Gordon, Iain, McSweeney, Chris, Leggett, Barbara and Morrison, Mark (2011). Numerical ecology validates a biogeographical distribution and gender-based effect on mucosa-associated bacteria along the human colon. ISME Journal, 5 (5), 801-809. doi: 10.1038/ismej.2010.177 |
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2011 Journal Article Tubular adenomas with minor villous changes show molecular features characteristic of tubulovillous adenomasIshii, Tatsushiro, Notohara, Kenji, Umapathy, Aarti, Mallitt, Kylie-Ann, Chikuba, Hiroshi, Moritani, Yukitoshi, Tanaka, Noriaki, Rosty, Christophe, Matsubara, Nagahide, Jass, Jeremy, Leggett, Barbara and Whitehall, Vicki (2011). Tubular adenomas with minor villous changes show molecular features characteristic of tubulovillous adenomas. American Journal of Surgical Pathology, 35 (2), 212-220. doi: 10.1097/PAS.0b013e318205df20 |
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2011 Journal Article The effects from DNA extraction methods on the evaluation of microbial diversity associated with human colonic tissueÓ Cuív, Páraic, de Carcer, Daniel Aguirre, Jones, Michelle, Klaassens, Eline S., Worthley, Daniel L., Whitehall, Vicki L. J., Kang, Seungha, McSweeney, Christopher S., Leggett, Barbara A. and Morrison, Mark (2011). The effects from DNA extraction methods on the evaluation of microbial diversity associated with human colonic tissue. Microbial Ecology, 61 (2), 353-362. doi: 10.1007/s00248-010-9771-x |
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2011 Journal Article DNA Methylation in the Rectal Mucosa Is Associated with Crypt Proliferation and Fecal Short-Chain Fatty AcidsWorthley, Daniel L., Whitehall, Vicki L. J., Le Leu, Richard K., Irahara, Natsumi, Buttenshaw, Ronald L., Mallitt, Kylie-Ann, Greco, Sonia A., Ramsnes, Ingunn, Winter, Jean, Hu, Ying, Ogino, Shuji, Young, Graeme P. and Leggett, Barbara A. (2011). DNA Methylation in the Rectal Mucosa Is Associated with Crypt Proliferation and Fecal Short-Chain Fatty Acids. Digestive Diseases and Sciences, 56 (2), 387-396. doi: 10.1007/s10620-010-1312-4 |
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2011 Journal Article p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancersBond, Catherine E., Umapathy, Aarti, Ramsnes, Ingunn, Greco, Sonia A., Zhao, Zhen Zhen, Mallitt, Kylie-Ann, Buttenshaw, Ron L., Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L.J. (2011). p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers. International Journal of Cancer, 130 (7), 1567-1576. doi: 10.1002/ijc.26175 |
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2010 Journal Article <i>Thrombospondin</i>-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylationGreco, Sonia A., Chia, June, Inglis, Kelly J., Cozzi, Sarah-Jane, Ramsnes, Ingunn, Buttenshaw, Ronald L., Spring, Kevin J., Boyle, Glen M., Worthley, Daniel L., Leggett, Barbara A. and Whitehall, Vicki L. J. (2010). Thrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylation. Bmc Cancer, 10 494. doi: 10.1186/1471-2407-10-494 |
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2010 Journal Article Hyperplastic Polyposis syndrome is associated with cigarette smoking, which may be a modifiable risk factorWalker, R. Griff, Landmann, Juergen K., Hewett, David G., Worthley, Daniel L., Buttenshaw, Ron L., Knight, Ngaire, Webb, Penny M., Whiteman, David C., Whitehall, Vicki L. and Leggett, Barbara A. (2010). Hyperplastic Polyposis syndrome is associated with cigarette smoking, which may be a modifiable risk factor. The American Journal of Gastroenterology, 105 (7), 1642-1647. doi: 10.1038/ajg.2009.757 |
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2010 Journal Article Re: Protection from right-and left-sided colorectal neoplasms after colonoscopy: Population-based studyWorthley, Daniel L., Hewett, David G., Spring, Kevin J., Whitehall, Vicki L. J. and Leggett, Barbara A. (2010). Re: Protection from right-and left-sided colorectal neoplasms after colonoscopy: Population-based study. Journal of the National Cancer Institute, 102 (13), 990-990. doi: 10.1093/jnci/djq189 |
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2010 Journal Article Role of the serrated pathway in colorectal cancer pathogenesisLeggett, Barbara and Whitehall, Vicki (2010). Role of the serrated pathway in colorectal cancer pathogenesis. Gastroenterology, 138 (6), 2088-2100. doi: 10.1053/j.gastro.2009.12.066 |
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2010 Journal Article DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancerWorthley, D. L., Whitehall, V. L. J., Buttenshaw, R. L., Irahara, N., Greco, S. A., Ramsnes, I., Mallitt, K-A, Le Leu, R. K., Winter, J., Hu, Y., Ogino, S., Young, G. P. and Leggett, B. A. (2010). DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. Oncogene, 29 (11), 1653-1662. doi: 10.1038/onc.2009.449 |
