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2015 Conference Publication Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin BlockadeWinkler, Ingrid G., Barbier, Valerie, Radford, Kristen J., Davies, Julie M., Levesque, Jean-Pierre, Smith, Theodore A. G., Fogler, William E. and Magnani, John L. (2015). Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade. 57th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 5-8 December 2015. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V126.23.512.512 |
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2015 Conference Publication Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm MacrophagesKaur, Simranpreet, Raggatt, Liza J., Jacobsen, Rebecca, Millard, Susan, Barbier, Valerie, Nowlan, Bianca, Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean P. and Pettit, Allison R. (2015). Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto, Japan, 17-19 September 2015. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2015.06.157 |
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2014 Conference Publication Bacterial liposaccharides block medullary erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+LY-6G+ Erythroid island macrophages in the bone marrowJacobsen, Rebecca, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2014). Bacterial liposaccharides block medullary erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+LY-6G+ Erythroid island macrophages in the bone marrow. 43rd Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), Montreal, Canada, 21-24 August 2014. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2014.07.147 |
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2014 Conference Publication Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271Winkler, Ingrid G., Barbier, Valerie, Perkins, Andrew C., Magnani, John L. and Levesque, Jean-Pierre (2014). Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271. 56th Annual Meeting of the American Society of Hematology, San Francisco, CA United States, 6-9 December 2014. Washington, DC United States: American Society of Hematology. |
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2014 Conference Publication Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from ChemotherapyWinkler, Ingrid G., Barbier, Valerie, Pattabiraman, Diwakar R., Gonda, Thomas J., Magnani, John L. and Levesque, Jean-Pierre (2014). Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from Chemotherapy. 56th Annual Meeting of the American Society of Hematology, San Francisco CA, United States, 6-9 December 2014. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V124.21.620.620 |
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2013 Conference Publication Hypoxia Inducible Factor (HIF)-2 alpha Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone MarrowForristal, Catherine E., Helwani, Falak, Martin, Sally, Nowlan, Bianca, Winkler, Ingrid G., Zannettino, Andrew and Levesque, Jean-Pierre (2013). Hypoxia Inducible Factor (HIF)-2 alpha Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone Marrow. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans, LA, United States, 7-10 December 2013. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V122.21.2895.2895 |
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2013 Conference Publication Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil RecoveryWinkler, Ingrid G., Barbier, Valerie, Nutt, Heather L., Hasnain, Sumaira Z., Levesque, Jean-Pierre, Magnani, John L. and McGuckin, Michael A. (2013). Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil Recovery. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY. |
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2013 Conference Publication Pharmacological stabilization of hypoxia-inducible factor-1α (HIF-1α) enhances hematopoietic stem cell mobilization in response to G-CSF and plerixaforForristal, Catherine, Nowlan, B., Barbier, Valerie, Winkler, Ingrid, Walkinshaw, Gail and Levesque, Jean-Pierre (2013). Pharmacological stabilization of hypoxia-inducible factor-1α (HIF-1α) enhances hematopoietic stem cell mobilization in response to G-CSF and plerixafor. 42nd Annual Scientific Meeting of the International Society for Experimental Hematology and Stem Cells (ISEH), Vienna, Austria, 22-25 August 2013. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2013.05.284 |
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2013 Conference Publication Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island MacrophagesJacobsen, Rebecca, Pettit, Allison R., Raggatt, Liza J., Nowlan, Bianca, Barbier, Valerie, Forristal, Catherine E., Winkler, Ingrid G. and Levesque, Jean-Pierre (2013). Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island Macrophages. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans, LA, United States, 7-10 December 2013. WASHINGTON: AMER SOC HEMATOLOGY. |
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2013 Conference Publication Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+MacrophagesJacobsen, Rebecca, Pettit, Allison, Barbier, Valerie, Nowlan, Bianca, Raggatt, Liza, Winkler, Ingrid and Levesque, Jean-Pierre (2013). Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+Macrophages. 42nd Annual Scientific Meeting of ISEH - Society for Hematology and Stem Cells, Vienna, Austria, 22-25 August 2013. Philadelphia, PA United States: Elsevier Inc. doi: 10.1016/j.exphem.2013.05.230 |
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2012 Conference Publication FG-4497, a Pharmacological Stabilizer of HIF-1 alpha Protein, Synergistically Enhances Hematopoietic Stem Cells (HSC) Mobilization in Response to G-CSF and PlerixaforForristal, Catherine E., Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid G., Walkinshaw, Gail and Levesque, Jean-Pierre (2012). FG-4497, a Pharmacological Stabilizer of HIF-1 alpha Protein, Synergistically Enhances Hematopoietic Stem Cells (HSC) Mobilization in Response to G-CSF and Plerixafor. 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta, GA, United States, 8-11 December 2012. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V120.21.216.216 |
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2012 Conference Publication Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the nicheLevesque, Jean-Pierre, Forristal, Catherine and Winkler, Ingrid (2012). Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the niche. 41st Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Amsterdam Netherlands, 23-26 August 2012. Philadelphia, PA United States: Elsevier. |
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2012 Conference Publication Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia by human AML oncogenes, and represents a potential therapeutic targetPattabiraman, Diwakar R., Shakhbazov, Konstantin, Barbier, Valerie, McGirr, Crystal, Krishnan, Keerthana, Mukhopadhyay, Pamela, Hawthorne, Paula, Trezise, Ann, Grimmond, Sean, Papathanasiou, Peter, Perkins, Andrew C., Levesque, Jean-Pierre, Alexander, Warren S., Winkler, Ingrid G. and Gonda, Thomas J. (2012). Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia by human AML oncogenes, and represents a potential therapeutic target. 54th Annual Meeting and Exposition of the American Society of Hematology (ASH), Atlanta, GA, United States, 8-11 Deceember, 2012. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V120.21.2402.2402 |
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2011 Conference Publication Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSFForristal, Catherine, Nowlan, Bianca, Barbier, Valerie, McCarthy, Domenica, Walkinshaw, Gail, Winkler, Ingrid G. and Levesque, Jean-Pierre (2011). Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology. |
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2011 Conference Publication Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone MarrowLevesque, Jean-Pierre, Barbier, Valerie, Nowlan, Bianca, McCarhty, Domenica and Winkler, Ingrid G. (2011). Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology. |
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2011 Conference Publication Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-LymphopoiesisLevesque, Jean-Pierre, Bendall, Linda J., Pettit, Allison R., Raggatt, Liza, Jacobsen, Rebecca, Barbier, Valarie, Nowlan, Bianca, Shen, Yi Shen, Sims, Natalie A. and Winkler, Ingrid G. (2011). Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology. |
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2010 Conference Publication The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesisShen, Y., Barbier, V., Winkler, I., Sims, N., Hendy, J. and Levesque, J. P. (2010). The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier. |
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2010 Conference Publication A molecular profile of the hematopoietic stem cell niche at the endosteumHelwani, F., Winkler, I., Price, G. and Levesque, J. P. (2010). A molecular profile of the hematopoietic stem cell niche at the endosteum. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier. |
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2010 Conference Publication Co-culture maintenance of functional haematopoietic stem cells and expansion of their progenyCook, M., Brooke, G., Doran, M., Winkler, I., Levesque, J. P. and Atkinson, K. (2010). Co-culture maintenance of functional haematopoietic stem cells and expansion of their progeny. 36th Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantat/9th Meeting of the EBMT Data-Management-Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Qual Management Meeting, Vienna Austria, Mar 21-24, 2010. LONDON: NATURE PUBLISHING GROUP. |
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2009 Conference Publication Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances ChemoresistanceWinkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Smith, Theodore, Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2009). Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 December 2009. Washington, DC, United States: American Society of Hematology. |
