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2025 Conference Publication Therapeutic endothelial E-selectin blockade boosts outcome of mobilized blood long-term transplant reconstitution by >25-fold in miceWinkler, Ingrid, Bisht, Kavita, Levesque, Jean-Pierre and Barbier, Valerie (2025). Therapeutic endothelial E-selectin blockade boosts outcome of mobilized blood long-term transplant reconstitution by >25-fold in mice. 54th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, Kumamoto, Japan, 24-27 September 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2025.105100 |
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2025 Conference Publication G-CSF-induced pain-like behaviors can be prevented by therapeutic blockade of vascular endothelial E-selectin in miceWinkler, Ingrid, Barbier, Valerie, Bisht, Kavita, Levesque, Jean-Pierre, Shatunova, Svetlana, Starobova, Hana and Vetter, Irina (2025). G-CSF-induced pain-like behaviors can be prevented by therapeutic blockade of vascular endothelial E-selectin in mice. 54th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, Kumamoto, Japan, 24-27 September 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2025.105098 |
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2025 Conference Publication Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophagesBisht, Kavita, Zhong, Ruiqing, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Tang, Yifu, Giri, Rabina, Amiss, Anna, Alexander, Kylie, Millard, Susan, Pettit, Allison, Winkler, Ingrid, Begun, Jakob and Levesque, Jean-Pierre (2025). Endotoxemia causes inflammatory bowel diseases-associated anemia and inflammation via TLR4 expressed by CD169+ macrophages. 54th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, Kumamoto, Japan, 24-27 September 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2025.105131 |
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2025 Journal Article Role and prognostic value of oncostatin M and its receptor OSMR in acute myeloid leukemia, myeloproliferative neoplasms and non-hematological malignanciesLévesque, Jean-Pierre, Bisht, Kavita, Alexander, Kylie A. and Winkler, Ingrid G. (2025). Role and prognostic value of oncostatin M and its receptor OSMR in acute myeloid leukemia, myeloproliferative neoplasms and non-hematological malignancies. Frontiers in Oncology, 15 1636570, 1636570. doi: 10.3389/fonc.2025.1636570 |
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2025 Journal Article Inhibition of the NLRP3 inflammasome using MCC950 reduces vincristine‐induced adverse effects in an acute lymphoblastic leukemia patient‐derived xenograft modelStarobova, Hana, McCalmont, Hannah, Shatunova, Svetlana, Tay, Nicolette, Smith, Christopher M., Robertson, Avril, Winkler, Ingrid, Lock, Richard B. and Vetter, Irina (2025). Inhibition of the NLRP3 inflammasome using MCC950 reduces vincristine‐induced adverse effects in an acute lymphoblastic leukemia patient‐derived xenograft model. HemaSphere, 9 (3) e70092, 1-3. doi: 10.1002/hem3.70092 |
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2024 Conference Publication Endothelial Protein C Receptor CD201 Enables Identification of Transplantable Mouse Hematopoietic Stem Cells in Inflammatory Conditions Unlike SCA1Bisht, Kavita, Shatunova, Svetlana, Barbier, Valerie, Winkler, Ingrid G. and Levesque, Jean-Pierre (2024). Endothelial Protein C Receptor CD201 Enables Identification of Transplantable Mouse Hematopoietic Stem Cells in Inflammatory Conditions Unlike SCA1. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-199946 |
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2024 Conference Publication Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated AnemiaBisht, Kavita, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Giri, Rabina, Amiss, Anna, Tang, Yifu, Alexander, Kylie, Millard, Susan, Winkler, Ingrid G., Pettit, Allison, Begun, Jakob and Levesque, Jean-Pierre (2024). Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-193349 |
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2024 Journal Article The role of the neuronal microenvironment in sensory function and pain pathophysiologyStarobova, Hana, Alshammari, Ammar, Winkler, Ingrid G. and Vetter, Irina (2024). The role of the neuronal microenvironment in sensory function and pain pathophysiology. Journal of Neurochemistry, 168 (11), 3620-3643. doi: 10.1111/jnc.15724 |
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2024 Conference Publication The Endothelial Protein C Receptor CD201 Identifies Transplantable Mouse Hematopoietic Stem Cells In Inflammatory Conditions Unlike SCA-1Bisht, Kavita, Shatunova, Svetlana, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2024). The Endothelial Protein C Receptor CD201 Identifies Transplantable Mouse Hematopoietic Stem Cells In Inflammatory Conditions Unlike SCA-1. 53rd Annual Scientific Meeting ISEH 2024, Chicago, IL United States, 29 August - 1 September 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.exphem.2024.104348 |
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2024 Journal Article Targeting hematologic malignancies by inhibiting E-selectin: A sweet spot for AML therapy?Uy, Geoffrey L., DeAngelo, Daniel J., Lozier, Jay N., Fisher, Dennis M., Jonas, Brian A., Magnani, John L., Becker, Pamela S., Lazarus, Hillard M. and Winkler, Ingrid G. (2024). Targeting hematologic malignancies by inhibiting E-selectin: A sweet spot for AML therapy?. Blood Reviews, 65 101184, 1-12. doi: 10.1016/j.blre.2024.101184 |
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2024 Journal Article Characterization of human engraftment and hemophagocytic lymphohistiocytosis in NSG-SGM3 neonate mice engrafted with purified CD34+ hematopoietic stem cellsLiam, O'Brien, Carina, Walpole, Leal-Rojas, Ingrid M., Svetlana, Shatunova, Andrew, Moore, Winkler, Ingrid G, Camille, Guillerey and Radford, Kristen J. (2024). Characterization of human engraftment and hemophagocytic lymphohistiocytosis in NSG-SGM3 neonate mice engrafted with purified CD34+ hematopoietic stem cells. Experimental Hematology, 130 104134, 104134. doi: 10.1016/j.exphem.2023.11.008 |
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2023 Journal Article Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification DevelopmentSalga, Marjorie, Samuel, Selwin G., Tseng, Hsu‐Wen, Gatin, Laure, Girard, Dorothée, Rival, Bastien, Barbier, Valerie, Bisht, Kavita, Shatunova, Svetlana, Debaud, Charlotte, Winkler, Ingrid G., Paquereau, Julie, Dinh, Aurélien, Genêt, Guillaume, Kerever, Sébastien, Abback, Paer‐Sélim, Banzet, Sébastien, Genêt, François, Lévesque, Jean‐Pierre and Alexander, Kylie A. (2023). Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development. Journal of Bone and Mineral Research, 38 (11), 1700-1717. doi: 10.1002/jbmr.4905 |
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2023 Book Chapter Imaging flow cytometric analysis of primary bone marrow erythroblastic islandsTay, Joshua, Bisht, Kavita, Winkler, Ingrid G. and Levesque, Jean-Pierre (2023). Imaging flow cytometric analysis of primary bone marrow erythroblastic islands. Spectral and imaging cytometry methods and protocols. (pp. 43-61) edited by Natasha S. Barteneva and Ivan A. Vorobjev. New York, NY: Humana Press Inc.. doi: 10.1007/978-1-0716-3020-4_3 |
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2021 Journal Article Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammationLévesque, Jean-Pierre, Summers, Kim M., Bisht, Kavita, Millard, Susan M., Winkler, Ingrid G. and Pettit, Allison R. (2021). Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation. Experimental Hematology, 103, 1-14. doi: 10.1016/j.exphem.2021.08.011 |
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2021 Journal Article Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilizationBisht, Kavita, McGirr, Crystal, Lee, Seo-Youn, Tseng, Hsu-Wen, Fleming, Whitney, Alexander, Kylie A., Matsumoto, Taichi, Barbier, Valérie, Sims, Natalie A., Müller-Newen, Gerhard, Winkler, Ingrid G., Bonig, Halvard and Lévesque, Jean-Pierre (2021). Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization. Leukemia, 36 (2), 333-347. doi: 10.1038/s41375-021-01413-z |
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2021 Journal Article Prostacyclin is an endosteal bone marrow niche component and its clinical analog iloprost protects hematopoietic stem cell potential during stressTay, Joshua, Barbier, Valerie, Helwani, Falak M, Price, Gareth R, Levesque, Jean-Pierre and Winkler, Ingrid G (2021). Prostacyclin is an endosteal bone marrow niche component and its clinical analog iloprost protects hematopoietic stem cell potential during stress. Stem Cells, 39 (11), 1532-1545. doi: 10.1002/stem.3438 |
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2021 Journal Article Adhesion to E-selectin primes macrophages for activation through AKT and mTORDavies, Julie M., Radford, Kristen J., Begun, Jakob, Levesque, Jean-Pierre and Winkler, Ingrid G. (2021). Adhesion to E-selectin primes macrophages for activation through AKT and mTOR. Immunology and Cell Biology, 99 (6) imcb.12447, 622-639. doi: 10.1111/imcb.12447 |
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2021 Journal Article Inteligência artificial e virtualização em ambientes virtuais de ensino e aprendizagem: desafios e perspectivas tecnológicasSantos, Sanval Ebert de Freitas, Jorge, Eduardo Manuel de Freitas and Winkler, Ingrid (2021). Inteligência artificial e virtualização em ambientes virtuais de ensino e aprendizagem: desafios e perspectivas tecnológicas. ETD - Educação Temática Digital, 23 (1), 2-19. doi: 10.20396/etd.v23i1.8656150 |
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2020 Journal Article Acute myeloid leukemia chemo-resistance is mediated by E-selectin receptor CD162 in bone marrow nichesErbani, Johanna, Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre and Winkler, Ingrid G. (2020). Acute myeloid leukemia chemo-resistance is mediated by E-selectin receptor CD162 in bone marrow niches. Frontiers in Cell and Developmental Biology, 8 668, 668. doi: 10.3389/fcell.2020.00668 |
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2020 Journal Article Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistanceBarbier, Valerie, Erbani, Johanna, Fiveash, Corrine, Davies, Julie M., Tay, Joshua, Tallack, Michael R., Lowe, Jessica, Magnani, John L., Pattabiraman, Diwakar R., Perkins, Andrew C., Lisle, Jessica, Rasko, John E. J., Levesque, Jean-Pierre and Winkler, Ingrid G. (2020). Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance. Nature Communications, 11 (1) 2042, 2042. doi: 10.1038/s41467-020-15817-5 |
