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2020 Journal Article Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrowTay, Joshua, Bisht, Kavita, McGirr, Crystal, Millard, Susan M., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow. Experimental Hematology, 82, 33-42. doi: 10.1016/j.exphem.2020.02.003 |
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2019 Conference Publication CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow NicheErbani, Johanna D., Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre, Magnani, John L. and Winkler, Ingrid G. (2019). CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-132233 |
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2019 Conference Publication Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling PathwaysWinkler, Ingrid G., Barbier, Valerie, Tay, Joshua, Levesque, Jean-Pierre, Magnani, John L., Fiveash, Corrine E. and Erbani, Johanna D. (2019). Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-132212 |
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2019 Journal Article Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixaforBisht, Kavita, McGirr, Crystal, Alexander, Kylie A, Fleming, Whitney, Sims, Natalie, Newen, Gerhard Müller-, Winkler, Ingrid G and Levesque, Jean-Pierre (2019). Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor. Blood, 134 (Supplement_1), 4469-4469. doi: 10.1182/blood-2019-127431 |
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2019 Journal Article Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cellsLukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102 |
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2019 Conference Publication Single Cell Profiling of Aortic Endothelium Identifies Hierarchy From Endovascular Progenitors to Differentiated CellsPatel, Jatin, Lukowski, Samuel L., Winkler, Ingrid, Tay, Joshua and Khosrotehrani, Kiarash (2019). Single Cell Profiling of Aortic Endothelium Identifies Hierarchy From Endovascular Progenitors to Differentiated Cells. Annual Scientific Meeting and Scientific Sessions of the American-Heart-Association on Vascular Discovery - From Genes to Medicine, Boston, MA United States, 14-16 May 2019. Philadelphia, PA United States: Lippincott Williams & Wilkins. |
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2019 Journal Article HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDRBisht, Kavita, Brunck, Marion E., Matsumoto, Taichi, McGirr, Crystal, Nowlan, Bianca, Fleming, Whitney, Keech, Thomas, Magor, Graham, Perkins, Andrew C., Davies, Julie, Walkinshaw, Gail, Flippin, Lee, Winkler, Ingrid G. and Levesque, Jean-Pierre (2019). HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR. Blood Advances, 3 (3), 406-418. doi: 10.1182/bloodadvances.2018017566 |
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2018 Journal Article Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftmentKaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663 |
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2018 Conference Publication Prostaglandin I-2 in the endosteal bone marrow niche as a novel regulator of hematopoietic stem cellsTay, Joshua, Levesque, Jean-Pierre, Helwani, Falak, Price, Gareth, Nowlan, Bianca, Barbier, Valerie and Winkler, Ingrid G. (2018). Prostaglandin I-2 in the endosteal bone marrow niche as a novel regulator of hematopoietic stem cells. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-115869 |
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2018 Conference Publication Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantationPettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117 |
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2018 Conference Publication Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vascultureWinkler, Ingrid G., Barbier, Valerie, Lowe, Jessica, Tay, Joshua, Magnani, John L., Marlton, Paula, Mills, Anthony K., Perkins, Andrew, Fiveash, Corrine E., Erbani, Johanna M. and Levesque, Jean-Pierre (2018). Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vasculture. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-120376 |
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2017 Conference Publication Macrophage involvement in the response of acute myeloid leukaemia to chemotherapyKeech, Thomas, McGirr, Crystal, Winkler, Ingrid G. and Levesque, Jean-Pierre (2017). Macrophage involvement in the response of acute myeloid leukaemia to chemotherapy. 59th Annual Meeting of the American Society of Hematology (ASH), Atlanta, GA USA, 9-12 December 2017. Washington, DC USA: American Society of Hematology. |
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2017 Conference Publication Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT SignalingWinkler, Ingrid G., Erbani, Johanna M., Barbier, Valerie, Davies, Julie M., Tay, Joshua, Fiveash, Corrine E., Lowe, Jessica, Tallack, Michael, Magnani, John L. and Levesque, Jean-Pierre (2017). Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling. 59th Annual Meeting of the American-Society-of-Hematology (ASH), Atlanta, GA, United States, 9-12 December 2017. Washington, DC, United States: American Society of Hematology. |
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2017 Journal Article Cellular players of hematopoietic stem cell mobilization in the bone marrow nicheTay, Joshua, Levesque, Jean‑Pierre and Winkler, Ingrid G. (2017). Cellular players of hematopoietic stem cell mobilization in the bone marrow niche. International Journal of Hematology, 105 (2), 129-140. doi: 10.1007/s12185-016-2162-4 |
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2017 Book Chapter The role of mesenchymal stem cells in hematopoiesisLevesque, Jean-Pierre, Jacobsen, Rebecca N. and Winkler, Ingrid G. (2017). The role of mesenchymal stem cells in hematopoiesis. The biology and therapeutic application of mesenchymal cells. (pp. 467-480) edited by Kerry Atkinson. Hoboken, NJ, United States: John Wiley and Sons. doi: 10.1002/9781118907474.ch32 |
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2016 Conference Publication Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In VivoGoh, Sal Lee, Levesque, Jean-Pierre, Petitt, Allison R., Barbier, Valarie and Winkler, Ingrid G. (2016). Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo. 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego Ca, Dec 03-06, 2016. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V128.22.2835.2835 |
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2016 Journal Article Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedsideLevesque, Jean-Pierre and Winkler, Ingrid G. (2016). Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedside. Current Stem Cell Reports, 2 (4), 356-367. doi: 10.1007/s40778-016-0066-0 |
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2016 Conference Publication Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stressTay, Joshua, Levesque, Jean-Pierre, Helwani, Falak, Price, Gareth, Barbier, Valerie, Nowlan, Bianca and Winkler, Ingrid (2016). Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stress. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.224 |
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2016 Conference Publication Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivoGoh, Sal Lee, Levesque, Jean-Pierre, Pettit, Allison, Barbier, Valerie, Jeanclos, Cecile and Winkler, Ingrid (2016). Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. |
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2016 Journal Article CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancerWu, Andy C., He, Yaowu, Broomfield, Amy, Paatan, Nicoll J., Harrington, Brittney S., Tseng, Hsu-Wen, Beaven, Elizabeth A., Kiernan, Deirdre M., Swindle, Peter, Clubb, Adrian B., Levesque, Jean-Pierre, Winkler, Ingrid G., Ling, Ming-Tat, Srinivasan, Bhuvana, Hooper, John D. and Pettit, Allison R. (2016). CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer. Journal of Pathology, 239 (2), 218-230. doi: 10.1002/path.4718 |
