2010 Conference Publication The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesisShen, Y., Barbier, V., Winkler, I., Sims, N., Hendy, J. and Levesque, J. P. (2010). The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier. |
2010 Journal Article Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused nichesWinkler, Ingrid G., Barbier, Valérie, Wadley, Robert, Zannettino, Andrew C. W., Williams, Sharon and Lévesque, Jean-Pierre (2010). Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches. Blood, 116 (3), 375-385. doi: 10.1182/blood-2009-07-233437 |
2010 Conference Publication Co-culture maintenance of functional haematopoietic stem cells and expansion of their progenyCook, M., Brooke, G., Doran, M., Winkler, I., Levesque, J. P. and Atkinson, K. (2010). Co-culture maintenance of functional haematopoietic stem cells and expansion of their progeny. 36th Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantat/9th Meeting of the EBMT Data-Management-Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Qual Management Meeting, Vienna Austria, Mar 21-24, 2010. LONDON: NATURE PUBLISHING GROUP. |
2009 Journal Article 38th annual meeting of the international society of experimental hematologyLevesque, Jean-Pierre and Winkler, Ingrid G. (2009). 38th annual meeting of the international society of experimental hematology. Expert Review of Hematology, 2 (6), 645-647. doi: 10.1586/ehm.09.61 |
2009 Conference Publication Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances ChemoresistanceWinkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Smith, Theodore, Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2009). Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 December 2009. Washington, DC, United States: American Society of Hematology. |
2009 Conference Publication Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistanceWinkler, I. G., Levesque, J. P., Barbier, V. and Nowlan, B. (2009). Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier. |
2009 Conference Publication Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating bloodLevesque, J. P., Barbier, V., Wadley, R. and Winkler, I. G. (2009). Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier. |
2009 Conference Publication Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilizationPettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082 |
2008 Conference Publication Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell MobilizationLevesque, Jean-Pierre, Sims, Natalie A., Bendall, Linda J., Shen, Yi and Winkler, Ingrid G. (2008). Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology. |
2008 Conference Publication The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in HematopoiesisShen, Yi, Barbier, Valerie, Winkler, Ingrid G., Hendy, Jean and Levesque, Jean-Pierre (2008). The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology. |
2008 Journal Article Mobilization of hematopoietic stem cells: state of the artLevesque, J-P. J. R. and Winkler, I.G. (2008). Mobilization of hematopoietic stem cells: state of the art. Current Opinion in Organ Transplantation, 13 (1), 53-58. doi: 10.1097/MOT.0b013e3282f42473 |
2007 Conference Publication Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-overWinkler, Ingrid G., Nowlan, Bianca, Barbier, Valerie and Levesque, Jean-Pierre (2007). Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 8-11 December 2007. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V110.11.609.609 |
2007 Journal Article Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrowLevesque, J. P., Winkler, I. G., Hendy, J., Williams, B., Helwani, F., Barbier, V., Nowlan, B. and Nilsson, S. K. (2007). Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow. Stem Cells, 25 (8), 1954-1965. doi: 10.1634/stemcells.2006-0688 |
2007 Book Chapter Mobilization of bone marrow-derived progenitorsLevesque, J.-P., Winkler, I. G., Larsen, S. R. and Rasko, J. E. J. (2007). Mobilization of bone marrow-derived progenitors. Bone Marrow-Derived Progenitors. (pp. 4-36) Berlin, Germany: Springer. |
2007 Journal Article Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cellsHerbert, Kirsten, Walkley, Carl R., Winkler, Ingrid G., Hendy, Jean, Olsen, Gemma Haines, Yuan, Yang-Dar, Chandraratna, Roshantha A., Prince, H. Miles, Lévesque, Jean-Pierre and Purton, Louise E. (2007). Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells. Cell Therapy and Islet Transplantation, 83 (4), 375-384. doi: 10.1097/01.tp.0000251376.75347.b4 |
2006 Conference Publication Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY)Levesque, Jean-Pierre, Winkler, Ingrid G., Hendy, Jean and Nilsson, Susan K. (2006). Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY). 48th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 9-12 December 2006. Washington, DC United States: American Society of Hematology. |
2005 Conference Publication G-CSF potently suppresses osteoblast activity in the bone marrowChristopher, M. J., Liu, F., Short, B., Simmons, P. J., Winkler, I., Levesque, J. P. and Link, D. C. (2005). G-CSF potently suppresses osteoblast activity in the bone marrow. 47th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 10-13 December 2005. Washington, DC, United States: American Society of Hematology. |
2005 Conference Publication The inhibition of the osteoblast niche during hematopoietic stem cell mobilization is an indirect effect involving mature bone marrow leukocytes, IL6 and soluble IL6 receptorLevesque, JP, Winkler, IG, Sims, N, Morris, H, Simmons, PJ and Takamatsu, Y (2005). The inhibition of the osteoblast niche during hematopoietic stem cell mobilization is an indirect effect involving mature bone marrow leukocytes, IL6 and soluble IL6 receptor. 47th Annual Meeting of the American-Society-of-Hematology, Atlanta Ga, Dec 10-13, 2005. WASHINGTON: AMER SOC HEMATOLOGY. doi: 10.1182/blood.V106.11.1966.1966 |
2005 Journal Article Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilizationWinkler, IG, Hendy, J, Coughlin, P, Horvath, A and Levesque, JP (2005). Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization. Journal of Experimental Medicine, 201 (7), 1077-1088. doi: 10.1084/jem.20042299 |
2005 Journal Article Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cellsEto, Tetsuya, Winkler, Ingrid, Purton, Louise E. and Levesque, Jean-Pierre (2005). Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells. Experimental Hematology, 33 (2), 232-242. doi: 10.1016/j.exphem.2004.10.018 |