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2010

Conference Publication

The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis

Shen, Y., Barbier, V., Winkler, I., Sims, N., Hendy, J. and Levesque, J. P. (2010). The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier.

The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis

2010

Journal Article

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

Winkler, Ingrid G., Barbier, Valérie, Wadley, Robert, Zannettino, Andrew C. W., Williams, Sharon and Lévesque, Jean-Pierre (2010). Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches. Blood, 116 (3), 375-385. doi: 10.1182/blood-2009-07-233437

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

2010

Conference Publication

Co-culture maintenance of functional haematopoietic stem cells and expansion of their progeny

Cook, M., Brooke, G., Doran, M., Winkler, I., Levesque, J. P. and Atkinson, K. (2010). Co-culture maintenance of functional haematopoietic stem cells and expansion of their progeny. 36th Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantat/9th Meeting of the EBMT Data-Management-Group/26th Meeting of the EBMT Nurses Group/2nd EBMT Qual Management Meeting, Vienna Austria, Mar 21-24, 2010. LONDON: NATURE PUBLISHING GROUP.

Co-culture maintenance of functional haematopoietic stem cells and expansion of their progeny

2009

Journal Article

38th annual meeting of the international society of experimental hematology

Levesque, Jean-Pierre and Winkler, Ingrid G. (2009). 38th annual meeting of the international society of experimental hematology. Expert Review of Hematology, 2 (6), 645-647. doi: 10.1586/ehm.09.61

38th annual meeting of the international society of experimental hematology

2009

Conference Publication

Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance

Winkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Smith, Theodore, Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2009). Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 December 2009. Washington, DC, United States: American Society of Hematology.

Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance

2009

Conference Publication

Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance

Winkler, I. G., Levesque, J. P., Barbier, V. and Nowlan, B. (2009). Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier.

Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance

2009

Conference Publication

Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood

Levesque, J. P., Barbier, V., Wadley, R. and Winkler, I. G. (2009). Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier.

Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood

2009

Conference Publication

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

Pettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

2008

Conference Publication

Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization

Levesque, Jean-Pierre, Sims, Natalie A., Bendall, Linda J., Shen, Yi and Winkler, Ingrid G. (2008). Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology.

Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization

2008

Conference Publication

The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis

Shen, Yi, Barbier, Valerie, Winkler, Ingrid G., Hendy, Jean and Levesque, Jean-Pierre (2008). The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology.

The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis

2008

Journal Article

Mobilization of hematopoietic stem cells: state of the art

Levesque, J-P. J. R. and Winkler, I.G. (2008). Mobilization of hematopoietic stem cells: state of the art. Current Opinion in Organ Transplantation, 13 (1), 53-58. doi: 10.1097/MOT.0b013e3282f42473

Mobilization of hematopoietic stem cells: state of the art

2007

Conference Publication

Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over

Winkler, Ingrid G., Nowlan, Bianca, Barbier, Valerie and Levesque, Jean-Pierre (2007). Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 8-11 December 2007. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V110.11.609.609

Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over

2007

Journal Article

Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow

Levesque, J. P., Winkler, I. G., Hendy, J., Williams, B., Helwani, F., Barbier, V., Nowlan, B. and Nilsson, S. K. (2007). Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow. Stem Cells, 25 (8), 1954-1965. doi: 10.1634/stemcells.2006-0688

Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow

2007

Book Chapter

Mobilization of bone marrow-derived progenitors

Levesque, J.-P., Winkler, I. G., Larsen, S. R. and Rasko, J. E. J. (2007). Mobilization of bone marrow-derived progenitors. Bone Marrow-Derived Progenitors. (pp. 4-36) Berlin, Germany: Springer.

Mobilization of bone marrow-derived progenitors

2007

Journal Article

Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells

Herbert, Kirsten, Walkley, Carl R., Winkler, Ingrid G., Hendy, Jean, Olsen, Gemma Haines, Yuan, Yang-Dar, Chandraratna, Roshantha A., Prince, H. Miles, Lévesque, Jean-Pierre and Purton, Louise E. (2007). Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells. Cell Therapy and Islet Transplantation, 83 (4), 375-384. doi: 10.1097/01.tp.0000251376.75347.b4

Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells

2006

Conference Publication

Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY)

Levesque, Jean-Pierre, Winkler, Ingrid G., Hendy, Jean and Nilsson, Susan K. (2006). Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY). 48th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 9-12 December 2006. Washington, DC United States: American Society of Hematology.

Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY)

2005

Conference Publication

G-CSF potently suppresses osteoblast activity in the bone marrow

Christopher, M. J., Liu, F., Short, B., Simmons, P. J., Winkler, I., Levesque, J. P. and Link, D. C. (2005). G-CSF potently suppresses osteoblast activity in the bone marrow. 47th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 10-13 December 2005. Washington, DC, United States: American Society of Hematology.

G-CSF potently suppresses osteoblast activity in the bone marrow

2005

Conference Publication

The inhibition of the osteoblast niche during hematopoietic stem cell mobilization is an indirect effect involving mature bone marrow leukocytes, IL6 and soluble IL6 receptor

Levesque, JP, Winkler, IG, Sims, N, Morris, H, Simmons, PJ and Takamatsu, Y (2005). The inhibition of the osteoblast niche during hematopoietic stem cell mobilization is an indirect effect involving mature bone marrow leukocytes, IL6 and soluble IL6 receptor. 47th Annual Meeting of the American-Society-of-Hematology, Atlanta Ga, Dec 10-13, 2005. WASHINGTON: AMER SOC HEMATOLOGY. doi: 10.1182/blood.V106.11.1966.1966

The inhibition of the osteoblast niche during hematopoietic stem cell mobilization is an indirect effect involving mature bone marrow leukocytes, IL6 and soluble IL6 receptor

2005

Journal Article

Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization

Winkler, IG, Hendy, J, Coughlin, P, Horvath, A and Levesque, JP (2005). Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization. Journal of Experimental Medicine, 201 (7), 1077-1088. doi: 10.1084/jem.20042299

Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization

2005

Journal Article

Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells

Eto, Tetsuya, Winkler, Ingrid, Purton, Louise E. and Levesque, Jean-Pierre (2005). Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells. Experimental Hematology, 33 (2), 232-242. doi: 10.1016/j.exphem.2004.10.018

Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells