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2019 Conference Publication CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow NicheErbani, Johanna D., Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre, Magnani, John L. and Winkler, Ingrid G. (2019). CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-132233 |
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2019 Conference Publication Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling PathwaysWinkler, Ingrid G., Barbier, Valerie, Tay, Joshua, Levesque, Jean-Pierre, Magnani, John L., Fiveash, Corrine E. and Erbani, Johanna D. (2019). Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-132212 |
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2019 Conference Publication Single Cell Profiling of Aortic Endothelium Identifies Hierarchy From Endovascular Progenitors to Differentiated CellsPatel, Jatin, Lukowski, Samuel L., Winkler, Ingrid, Tay, Joshua and Khosrotehrani, Kiarash (2019). Single Cell Profiling of Aortic Endothelium Identifies Hierarchy From Endovascular Progenitors to Differentiated Cells. Annual Scientific Meeting and Scientific Sessions of the American-Heart-Association on Vascular Discovery - From Genes to Medicine, Boston, MA United States, 14-16 May 2019. Philadelphia, PA United States: Lippincott Williams & Wilkins. |
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2018 Conference Publication Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantationPettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117 |
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2018 Conference Publication Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vascultureWinkler, Ingrid G., Barbier, Valerie, Lowe, Jessica, Tay, Joshua, Magnani, John L., Marlton, Paula, Mills, Anthony K., Perkins, Andrew, Fiveash, Corrine E., Erbani, Johanna M. and Levesque, Jean-Pierre (2018). Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vasculture. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-120376 |
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2018 Conference Publication Prostaglandin I-2 in the endosteal bone marrow niche as a novel regulator of hematopoietic stem cellsTay, Joshua, Levesque, Jean-Pierre, Helwani, Falak, Price, Gareth, Nowlan, Bianca, Barbier, Valerie and Winkler, Ingrid G. (2018). Prostaglandin I-2 in the endosteal bone marrow niche as a novel regulator of hematopoietic stem cells. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-115869 |
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2017 Conference Publication Macrophage involvement in the response of acute myeloid leukaemia to chemotherapyKeech, Thomas, McGirr, Crystal, Winkler, Ingrid G. and Levesque, Jean-Pierre (2017). Macrophage involvement in the response of acute myeloid leukaemia to chemotherapy. 59th Annual Meeting of the American Society of Hematology (ASH), Atlanta, GA USA, 9-12 December 2017. Washington, DC USA: American Society of Hematology. |
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2017 Conference Publication Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT SignalingWinkler, Ingrid G., Erbani, Johanna M., Barbier, Valerie, Davies, Julie M., Tay, Joshua, Fiveash, Corrine E., Lowe, Jessica, Tallack, Michael, Magnani, John L. and Levesque, Jean-Pierre (2017). Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling. 59th Annual Meeting of the American-Society-of-Hematology (ASH), Atlanta, GA, United States, 9-12 December 2017. Washington, DC, United States: American Society of Hematology. |
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2016 Conference Publication Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In VivoGoh, Sal Lee, Levesque, Jean-Pierre, Petitt, Allison R., Barbier, Valarie and Winkler, Ingrid G. (2016). Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo. 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego Ca, Dec 03-06, 2016. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V128.22.2835.2835 |
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2016 Conference Publication Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stressTay, Joshua, Levesque, Jean-Pierre, Helwani, Falak, Price, Gareth, Barbier, Valerie, Nowlan, Bianca and Winkler, Ingrid (2016). Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stress. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.224 |
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2016 Conference Publication Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivoGoh, Sal Lee, Levesque, Jean-Pierre, Pettit, Allison, Barbier, Valerie, Jeanclos, Cecile and Winkler, Ingrid (2016). Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. |
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2016 Conference Publication Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptorsBisht, Kavita, Jacobsen, Rebecca, Nowlan, Bianca, McGirr, Crystal, Brunck, Marion, Keech, Thomas, Winkler, Ingrid G. and Levesque, Jean-Pierre (2016). Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptors. 58th Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V128.22.546.546 |
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2016 Conference Publication Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf ReceptorsBisht, Kavita, Jacobsen, Rebecca, Brunck, Marion, Keech, Thomas, McGirr, Crystal, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2016). Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf Receptors. 45th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.096 |
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2016 Conference Publication Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantationLevesque, Jean-Pierre, Kaur, Simranpreet, Jacobsen, Rebecca, Millard, Susan, Batoon, Lena, Winkler, Ingrid, Macdonald, Kelli, Perkins, Andrew, Hume, David, Raggatt, Liza and Pettit, Allison (2016). Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation. 45th Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, San Diego, CA, United States, 25-28 August, 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.049 |
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2016 Conference Publication Alleviation of Acute Drug-Induced Liver Injury Following Acetaminophen Overdose by Therapeutic Blockade of E-Selectin in Preclinical Mouse ModelOancea, Iulia, Barbier, Valerie, Chee, David, Lourie, Rohan, Movva, Ramya, Proctor, Martina A., Begun, Jakob, Magnani, John L., Florin, Timothy H. and Winkler, Ingrid (2016). Alleviation of Acute Drug-Induced Liver Injury Following Acetaminophen Overdose by Therapeutic Blockade of E-Selectin in Preclinical Mouse Model. 57th Annual Meeting and Residents Fellow Conference of the Society for Surgery of the Alimentary Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(16)33483-7 |
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2016 Conference Publication Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantationKaur, S., Raggatt, L. J., Jacobsen, R. N., Millard, S., Batoon, L., Winkler, I. G., Macdonald, K. P. A., Perkins, A. C., Hume, D. A., Levesque, J. P. and Pettit, A. R. (2016). Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb ActivationWinkler, Ingrid G., Barbier, Valerie, Ward, Micheal, Tallack, Michael, Lowe, Jessica, Davies, Julie, Erbani, Johanna, Magnani, John L. and Levesque, Jean-Pierre (2016). Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb Activation. 58th Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.v128.22.2823.2823 |
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2015 Conference Publication Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin BlockadeWinkler, Ingrid G., Barbier, Valerie, Radford, Kristen J., Davies, Julie M., Levesque, Jean-Pierre, Smith, Theodore A. G., Fogler, William E. and Magnani, John L. (2015). Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade. 57th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 5-8 December 2015. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V126.23.512.512 |
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2015 Conference Publication Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm MacrophagesKaur, Simranpreet, Raggatt, Liza J., Jacobsen, Rebecca, Millard, Susan, Barbier, Valerie, Nowlan, Bianca, Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean P. and Pettit, Allison R. (2015). Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto, Japan, 17-19 September 2015. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2015.06.157 |
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2014 Conference Publication Bacterial liposaccharides block medullary erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+LY-6G+ Erythroid island macrophages in the bone marrowJacobsen, Rebecca, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2014). Bacterial liposaccharides block medullary erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+LY-6G+ Erythroid island macrophages in the bone marrow. 43rd Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), Montreal, Canada, 21-24 August 2014. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2014.07.147 |
