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2004

Journal Article

Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein

Wang, Ruobing, Epstein, Judith, Charoenvit, Yupin, Baraceros, Fe Maria, Rahardjo, Nancy, Gay, Tanya, Banania, Jo-Glenna, Chattopadhyay, Rana, de la Vega, Patricia, Richie, Thomas L., Tornieporth, Nadia, Doolan, Denise L., Kester, Kent E., Heppner, D. Gray, Norman, Jon, Carucci, Daniel J., Cohen, Joe D. and Hoffman, Stephen L. (2004). Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein. Journal of immunology, 172 (9), 5561-5569. doi: 10.4049/jimmunol.172.9.5561

Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein

2003

Journal Article

Utilization of genomic sequence information to develop malaria vaccines

Doolan, D. L., Aguiar, J. C., Weiss, W. R., Sette, A., Felgner, P. L., Regis, D. P., Quinones-Casas, P., Yates, J. R. III, Blair, P. L., Richie, T. L., Hoffman, S. L. and Carucci, D. J. (2003). Utilization of genomic sequence information to develop malaria vaccines. Journal of experimental biology, 206 (21), 3789-3802. doi: 10.1242/jeb.00615

Utilization of genomic sequence information to develop malaria vaccines

2003

Journal Article

Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

Doolan, Denise, Southwood, S., Freilich, D. A., Sidney, J., Graber, N. L., Shatney, L., Bebris, L., Florens, L., Dobano, C., Witney, A.A., Apella, E., Hoffman, S. L., Yates, J. R. 3rd, Carucci, D. J. and Sette, A. (2003). Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data. Proceedings of the National Academy of Sciences of the United States of America, 100 (17), 9952-9957. doi: 10.1073/pnas.1633254100

Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

2003

Conference Publication

Third meeting on Novel Adjuvants Currently in or Close to Clinical Testing World Health Organization - Organisation Mondiale de la Santé, Fondation Mérieux, Annecy, France, 7-9 January 2002

Engers, Howard, Kieny, Marie Paule, Malhotra, Pawan, Pink, J. Richard, Davies, Gwyn, Kensil, Charlotte Read, Jeannin, Pascale, Aubry, Jean-Pierre, Goetsch, Liliane, Delneste, Yves, Bonnefoy, Jean-Yves, Revets, Hilde, De Baetselier, Patrick, Steward, Michael, Fritchley, Sarah J., Bright, Jeremy R., Oldroyd, Rodney G., Affleck, Louise J., Ross, Ted M., Holder, Anthony A., Smith, Richard A.G., Kenney, Richard, Glenn, Gregory, Czerkinsky, Cecil, Del Giudice, Giuseppe, Zurbriggen, Rinaldo, Glück, Reinhard, Drane, Debbie, Pearse, Martin ... Sedegah, M. (2003). Third meeting on Novel Adjuvants Currently in or Close to Clinical Testing World Health Organization - Organisation Mondiale de la Santé, Fondation Mérieux, Annecy, France, 7-9 January 2002. Elsevier BV. doi: 10.1016/S0264-410X(03)00164-6

Third meeting on Novel Adjuvants Currently in or Close to Clinical Testing World Health Organization - Organisation Mondiale de la Santé, Fondation Mérieux, Annecy, France, 7-9 January 2002

2002

Journal Article

Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participation

Brice, Gary T., Graber, Norma L., Carucci, Daniel J. and Doolan, Denise L. (2002). Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participation. Journal of leukocyte biology, 72 (6), 1164-1171. doi: 10.1189/jlb.72.6.1164

Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participation

2002

Journal Article

Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649))

Gramzinski, Robert A., Doolan, Denise L., Sedegah, Martha, Davis, Heather L., Krieg, Arthur M. and Hoffman, Stephen L. (2002). Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649)). Infection and Immunity, 70 (9). doi: 10.1128/IAI.70.9.5338.2002

Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649))

2002

Journal Article

Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations

Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., Majam, Victoria F., Belmonte, Arnel, Lu, Minh, Belmonte, Maria, Carucci, Daniel J. and Hoffman, Stephen L. (2002). Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations. Infection and immunity, 70 (7), 3493-3499. doi: 10.1128/IAI.70.7.3493-3499.2002

Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations

2002

Journal Article

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

Hoffman, Stephen L., Goh, Lucy M. L., Luke, Thomas C., Schneider, Imogene, Le, Thong P., Doolan, Denise L., Sacci, John, De la Vega, Patricia, Dowler, Megan, Paul, Chris, Gordon, Daniel M., Stoute, Jose A., Preston Church, L. W., Sedegah, Martha, Gray Heppner, D., Ripley Ballou, W. and Richie, Thomas L. (2002). Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. Journal of Infectious Diseases, 185 (8), 1155-1164. doi: 10.1086/339409

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

2002

Book Chapter

Assessing antigen-specific CD8+ CTL responses in humans

Doolan, Denise L. (2002). Assessing antigen-specific CD8+ CTL responses in humans. Malaria Methods and Protocols. (pp. 445-456) edited by Denise L. Doolan. New York, NY, United States: Humana Press. doi: 10.1385/1-59259-271-6:445

Assessing antigen-specific CD8+ CTL responses in humans

2002

Journal Article

A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note)

Doolan, Denise L. and Graber, Norma L. (2002). A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note). Delivery, 22, 6-7.

A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note)

2002

Journal Article

Nucleic acid vaccines against malaria

Doolan, Denise L. and Hoffman, Stephen L. (2002). Nucleic acid vaccines against malaria. Chemical Immunology, 80, 308-321. doi: 10.1159/000058851

Nucleic acid vaccines against malaria

2002

Book Chapter

DNA vaccination

Hedstrom, Richard C. and Doolan, Denise L. (2002). DNA vaccination. Malaria methods and protocols. (pp. 347-59) edited by Denise L. Doolan. New York, NY, United States: Humana Press. doi: 10.1385/1-59259-271-6:347

DNA vaccination

2001

Journal Article

Foreword--MBP thematic issue on genomics

Doolan, D. L., Coppel, R. L. and Waters, A. P. (2001). Foreword--MBP thematic issue on genomics. Molecular and Biochemical Parasitology, 118 (2), 127-8. doi: 10.1016/s0166-6851(01)00389-9

Foreword--MBP thematic issue on genomics

2001

Journal Article

Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy

Witney, Adam A., Doolan, Denise L., Anthony, Robert M., Weiss, Walter R., Hoffman, Stephen L. and Carucci, Daniel J. (2001). Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy. Molecular and Biochemical Parasitology, 118 (2), 233-245. doi: 10.1016/S0166-6851(01)00372-3

Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy

2001

Journal Article

Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells

Brice, G. T., Graber, N. L., Hoffman, S. L. and Doolan, D. L. (2001). Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells. Journal of Immunological Methods, 257 (1-2), 55-69. doi: 10.1016/s0022-1759(01)00446-x

Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells

2001

Journal Article

Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine

Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., Hedstrom, Richard C., Rahardjo, Nancy, Gay, Tanya, Hobart, Peter, Stout, Rick, Jones, Trevor R., Richie, Thomas L., Parker, Suezanne E., Doolan, Denise L., Norman, Jon and Hoffman, Stephen L. (2001). Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine. Proceedings of the National Academy of Sciences of the United States of America, 98 (19), 10817-10822. doi: 10.1073/pnas.181123498

Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine

2001

Journal Article

DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation

Doolan, Denise L and Hoffman, Stephen L (2001). DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation. International Journal for Parasitology, 31 (8), 753-762. doi: 10.1016/S0020-7519(01)00184-9

DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation

2001

Journal Article

Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice

Gramzinski, R. A., Doolan, D. L., Sedegah, M., Davis, H. L., Krieg, A. M. and Hoffman, S. L. (2001). Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infection and Immunity, 69 (3), 1643-1649. doi: 10.1128/IAI.69.3.1643-1649.2001

Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice

2000

Journal Article

Malaria vaccines-targeting infected hepatocytes

Hoffman, Stephen L. and Doolan, Denise L. (2000). Malaria vaccines-targeting infected hepatocytes. Nature Medicine, 6 (11), 1218-1219. doi: 10.1038/81315

Malaria vaccines-targeting infected hepatocytes

2000

Journal Article

HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas

Ravichandran, M., Doolan, D. L., Cox-Singh, J., Hoffman, S. L. and Singh, B. (2000). HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. Parasite Immunology, 22 (9), 469-473. doi: 10.1046/j.1365-3024.2000.00324.x

HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas