|
2009 Conference Publication IDENTIFICATION OF HLA RESTRICTED CD8+T-CELL EPITOPES ON THE <i>PLASMODIUM FALCIPARUM</i> AMA1 PROTEINSedegah, Martha, Kim, Yohan, McGrath, Shannon, Ganeshan, Harini, Lejano, Jennylynn, Abot, Stephen, Banania, Glena, Belmonte, Maria, Sayo, Renato, Farooq, Fouzia, Doolan, Denise L., Peters, Bjoern, Bruder, Joseph, King, Christopher R., Soissons, Lorraine, Diggs, Carter, Ockenhouse, Christian F., Hollingdale, Michael, Sette, Alessandro and Richie, Thomas L. (2009). IDENTIFICATION OF HLA RESTRICTED CD8+T-CELL EPITOPES ON THE PLASMODIUM FALCIPARUM AMA1 PROTEIN. 58th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Washington Dc, Nov 18-22, 2009. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2009 Conference Publication SAFETY, TOLERABILITY, IMMUNOGENICITY AND PROTECTIVE EFFICACY OF AN ADENOVIRUS-VECTORED <i>PLASMODIUM FALCIPARUM</i> MALARIA VACCINE IN HEALTHY, MALARIA-NAIVE ADULTSTamminga, C., Sedegah, M., Chuang, I., Regis, D., Epstein, J. E., Spring, M., Mendoza-Silveiras, J., Steinbeiss, V., Fedders, C., Reyes, S., Parekh, F., Williams, F., Smith, K., Maiolatesi, S., Doolan, D. L., Limbach, K., Patterson, N. B., Bruder, J., King, C. R., Soisson, L., Diggs, C., Ockenhouse, C. and Richie, T. L. (2009). SAFETY, TOLERABILITY, IMMUNOGENICITY AND PROTECTIVE EFFICACY OF AN ADENOVIRUS-VECTORED PLASMODIUM FALCIPARUM MALARIA VACCINE IN HEALTHY, MALARIA-NAIVE ADULTS. 58th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Washington Dc, Nov 18-22, 2009. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2009 Journal Article Sterile protection ,against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: Comparison of heterologous prime boost strategiesJiang, George, Shi, Meng, Conteh, Solomon, Richie, Nancy, Banania, Glenna, Geneshan, Harini, Valencia, Anais, Singh, Priti, Aguiar, Joao, Limbach, Keith, Kamrud, Kurt I., Rayner, Jonathan, Smith, Jonathan, Bruder, Joseph T., King, C. Richter, Tsuboi, Takafumi, Takeo, Satoru, Endo, Yaeta, Doolan, Denise L., Richie, Thomas L. and Weiss, Walter R. (2009). Sterile protection ,against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: Comparison of heterologous prime boost strategies. PloS one, 4 (8) e6559, e6559 -1-e6559 -12. doi: 10.1371/journal.pone.0006559 |
|
2009 Journal Article Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malariaWoodberry, Tonia, Pinzon-Charry, Alberto, Piera, Kim A., Panpisutchai, Yawalak, Engwerda, Christian R., Doolan, Denise L., Salwati, Ervi, Kenangalem, Enny, Tjitra, Emiliana, Price, Ric N., Good, Michael F. and Anstey, Nicholas M. (2009). Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria. Malaria Journal, 8 (1) 122, 122.1-122.10. doi: 10.1186/1475-2875-8-122 |
|
2009 Journal Article Plasmodium: Mammalian codon optimization of malaria plasmid DNA vaccines enhances antibody responses but not T cell responses nor protective immunityDobañoa, Carlota, Sedegah, Martha, Rogers, William O., Kumar, Sanjai, Zheng, Hong, Hoffman, Stephen L. and Doolan, Denise (2009). Plasmodium: Mammalian codon optimization of malaria plasmid DNA vaccines enhances antibody responses but not T cell responses nor protective immunity. Experimental Parasitology, 122 (2), 112-123. doi: 10.1016/j.exppara.2009.02.010 |
|
2009 Journal Article Meta-analysis of immune epitope data for all Plasmodia: overview and applications for malarial immunobiology and vaccine-related issuesVaughan, K., Blythe, M., Greenbaum, J., Zhang, Q., Peters, B., Doolan, D.L. and Sette, A. (2009). Meta-analysis of immune epitope data for all Plasmodia: overview and applications for malarial immunobiology and vaccine-related issues. Parasite Immunology, 31 (2), 78-97. doi: 10.1111/j.1365-3024.2008.01077.x |
|
2009 Journal Article Acquired immunity to malariaDoolan, Denise L., Dobano, Carlota and Baird, J. Kevin (2009). Acquired immunity to malaria. Clinical Microbiology Reviews, 22 (1), 13-26. doi: 10.1128/CMR.00025-08 |
|
2008 Conference Publication PROFILING PROTECTIVE HUMORAL IMMUNE RESPONSES TO <i>PLASMODIUM FALCIPARUM</i> BY PROTEIN MICROARRAY IN A LONGITUDINAL STUDY IN MALICrompton, Peter D., Kayala, Matt, Traore, Boubacar, Weiss, Greta, Burk, Chad, Kayentao, Kassoum, Ongoiba, Aissata, Doumbo, Safiatou, Miller, Louis H., Doumbo, Ogobara K., Doolan, Denise L., Baldi, Pierre, Felgner, Philip L. and Pierce, Susan K. (2008). PROFILING PROTECTIVE HUMORAL IMMUNE RESPONSES TO PLASMODIUM FALCIPARUM BY PROTEIN MICROARRAY IN A LONGITUDINAL STUDY IN MALI. 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, New Orleans La, Dec 07-11, 2008. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2008 Conference Publication SAFETY AND TOLERABILITY OF A MULTI-STAGE, MULTI-ANTIGEN ADENOVIRUS-VECTORED <i>PLASMODIUM FALCIPARUM</i> MALARIA VACCINE, IN HEALTHY, MALARIA-NAIVE ADULTSTamminga, Cindy, Chuang, Ilin, Regis, David, Mendoza-Silveiras, Jose, Epstein, Judith E., Parekh, Falgunee, Reyes, Sharina, Steinbeiss, Victoria, Fedders, Charlotte, Maiolatesi, Santina, Smith, Kathryn, Williams, Francis, Sedegah, Martha, Doolan, Denise L., Limbach, Keith, Patterson, Noelle B., Spring, Michele, Bruder, Joseph T., King, C. R., Soisson, Lorraine, Diggs, Carter, Ockenhouse, Christian F. and Richie, Thomas (2008). SAFETY AND TOLERABILITY OF A MULTI-STAGE, MULTI-ANTIGEN ADENOVIRUS-VECTORED PLASMODIUM FALCIPARUM MALARIA VACCINE, IN HEALTHY, MALARIA-NAIVE ADULTS. 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, New Orleans La, Dec 07-11, 2008. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2008 Conference Publication IMMUNOGENICITY OF TWO DOSES OF A MULTI-STAGE, MULTI-ANTIGEN ADENOVIRUS-VECTORED <i>PLASMODIUM FALCIPARUM</i> MALARIA VACCINE IN A PHASE 1 TRIALSedegah, Martha, McGrath, Shannon, Regis, David, Chuang, Ilin, Ganeshan, Harini, Abot, Stephen, Banania, Glena, Manohar, Nalini, Doolan, Denise, Limbach, Keith, House, Brent, Aguiarl, Joao, Long, Carole, Bruder, Joseph, King, Christopher, Patterson, Noelle, Tamminga, Cindy, Epstein, Judith, Mendoza-Silveiras, Jose, Williams, Frank, Soisson, Lorraine, Diggs, Carter, Ockenhouse, Christopher and Richie, Thomas (2008). IMMUNOGENICITY OF TWO DOSES OF A MULTI-STAGE, MULTI-ANTIGEN ADENOVIRUS-VECTORED PLASMODIUM FALCIPARUM MALARIA VACCINE IN A PHASE 1 TRIAL. 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, New Orleans La, Dec 07-11, 2008. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2008 Conference Publication DEVELOPMENT OF A MULTI-ANTIGEN MULTI-STAGE ADENOVECTOR-BASED MALARIA VACCINE THAT INDUCES ROBUST T-CELL AND ANTIBODY RESPONSESBruder, Joseph T., Chen, Ping, Stefaniak, Maureen E., Semenova, Elena, Limbach, Keith, Patterson, Noelle B., Konovalova, Svetlana, Thomas, Charlie, Campo, Joseph J., Ettyreddy, Damodar, McVey, Duncan, Long, Carole A., Li, Sheng, Locke, Emily, Richie, Thomas L., King, C. Richter and Doolan, Denise L. (2008). DEVELOPMENT OF A MULTI-ANTIGEN MULTI-STAGE ADENOVECTOR-BASED MALARIA VACCINE THAT INDUCES ROBUST T-CELL AND ANTIBODY RESPONSES. 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, New Orleans La, Dec 07-11, 2008. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2008 Conference Publication ADVANCED GENERATION ADENO-BASED VECTORS FOR MALARIA VACCINE DEVELOPMENTBruder, Joseph T., Chen, Ping Ping, Semenova, Elena, Thomas, Charlie, Hamilton, Melissa, Patterson, Noelle B., Stefaniak, Maureen E., Limbach, Keith, Richie, Thomas L., Gall, Jason, King, C. R., McVey, Duncan and Doolan, Denise L. (2008). ADVANCED GENERATION ADENO-BASED VECTORS FOR MALARIA VACCINE DEVELOPMENT. 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, New Orleans La, Dec 07-11, 2008. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2008 Conference Publication A PLASMODIUM FALCIPARUM MULTI-ANTIGEN MULTI-STAGE PLASMID DNA PRIME/ADENOVECTOR BOOST VACCINE, NMRC-M3V-D/AD-PFCA, IS IMMUNOGENIC IN BALB/C MICEPatterson, Noelle B., Ganeshan, Harini, Abot, Esteban, Banania, JoGlenna, Lejano, Jennylynn N., Manohar, Nalini, Gowda, Kalpana, Limbach, Keith, McGrath, Shannon, Marshall, Stephanie A., Ferrari, Marilyn E., Bruder, Joseph T., King, C. Richter, Doolan, Denise L., Richie, Thomas L. and Sedegah, Martha (2008). A PLASMODIUM FALCIPARUM MULTI-ANTIGEN MULTI-STAGE PLASMID DNA PRIME/ADENOVECTOR BOOST VACCINE, NMRC-M3V-D/AD-PFCA, IS IMMUNOGENIC IN BALB/C MICE. 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, New Orleans La, Dec 07-11, 2008. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2008 Conference Publication THE FIRST GENERATION <i>PLASMODIUM</i> <i>FALCIPARUM</i> AMA-1 BASED MONOVALENT ADENOVECTOR VACCINE AND THE SECOND GENERATION BIVALENT ADENOVECTOR VACCINE EXPRESSING <i>PLASMODIUM FALCIPARUM</i> AMA-1 AND MSP1-42 ELICIT ROBUST FUNCTIONAL ANTIBODIES IN NZW RABBITPatterson, Noelle B., Bruder, Joseph T., Limbach, Keith, Moretz, Samuel E., Zhou, Hong, Diouf, Ababacar, King, C. Richter, Gowda, Kalpana, Chen, Ping, Konovalova, Svetlana, Bergmann-Leitner, Elke S., Locke, Emily, Soisson, Lorraine, Diggs, Carter, Angov, Evelina, Long, Carole A., Richie, Thomas L. and Doolan, Denise L. (2008). THE FIRST GENERATION PLASMODIUM FALCIPARUM AMA-1 BASED MONOVALENT ADENOVECTOR VACCINE AND THE SECOND GENERATION BIVALENT ADENOVECTOR VACCINE EXPRESSING PLASMODIUM FALCIPARUM AMA-1 AND MSP1-42 ELICIT ROBUST FUNCTIONAL ANTIBODIES IN NZW RABBIT. 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, New Orleans La, Dec 07-11, 2008. MCLEAN: AMER SOC TROP MED & HYGIENE. |
|
2008 Journal Article Profiling humoral immune responses to P. falciparum infection with protein microarraysDoolan, Denise L., Mu, Yunxiang, Una, Berkay, Sundaresh, Suman, Hirst, Siddiqua, Valdez, Conrad and et al. (2008). Profiling humoral immune responses to P. falciparum infection with protein microarrays. Proteomics, 8 (22), 4680-4694. doi: 10.1002/pmic.200800194 |
|
2008 Journal Article The path of discoveryDoolan, Denise L. (2008). The path of discovery. Human Vaccines, 4 (5), 324-327. doi: 10.4161/hv.4.5.6707 |
|
2008 Journal Article Alphavirus replicon particles are highly immunogenic in the murine malaria model by homologous or heterologous immunizationDobano, C., Weiss, W. R., Kamrud, K. I., Chulay, J. D., Smith, J., Carucci, D. J. and Doolan, D. L. (2008). Alphavirus replicon particles are highly immunogenic in the murine malaria model by homologous or heterologous immunization. The Open Vaccine Journal, 1, 27-37. |
|
2008 Journal Article Transcriptionally active PCR for antigen identification and vaccine development: In vitro genome-wide screening and in vivo immunogenicityRegis, David P., Dobaño, Carlota, Quiñones-Olson, Paola, Liang, Xiaowu, Graber, Norma L., Stefaniak, Maureen E., Campo, Joseph J., Carucci, Daniel J., Roth, David A., He, Huaping, Felgner, Philip L. and Doolan, Denise L. (2008). Transcriptionally active PCR for antigen identification and vaccine development: In vitro genome-wide screening and in vivo immunogenicity. Molecular and Biochemical Parasitology, 158 (1), 32-45. doi: 10.1016/j.molbiopara.2007.11.009 |
|
2007 Journal Article Status of malaria vaccine R&D in 2007Doolan, Denise L. and Stewart, V. Ann (2007). Status of malaria vaccine R&D in 2007. Expert Review of Vaccines, 6 (6), 903-905. doi: 10.1586/14760584.6.6.903 |
|
2007 Conference Publication Developing DNA-prime adenovirus-boost vaccines for the prevention of malariaChuang, Ilin, Regis, David R., Sedegah, Martha, Mendoza-Silveiras, Jose, Bruder, Joseph T., King, Richter C., Patterson, Noelle B., Limbach, Keith, Casares, Sofia, Maiolatesi, Santina, Soisson, Lorraine, Diggs, Carter, Weiss, Walter, Doolan, Denise L. and Richie, Thomas L. (2007). Developing DNA-prime adenovirus-boost vaccines for the prevention of malaria. 56th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Philadelphia Pa, Nov 04-08, 2007. MCLEAN: AMER SOC TROP MED & HYGIENE. |
