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2001 Journal Article Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in miceGramzinski, R. A., Doolan, D. L., Sedegah, M., Davis, H. L., Krieg, A. M. and Hoffman, S. L. (2001). Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infection and Immunity, 69 (3), 1643-1649. doi: 10.1128/IAI.69.3.1643-1649.2001 |
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2000 Journal Article Malaria vaccines-targeting infected hepatocytesHoffman, Stephen L. and Doolan, Denise L. (2000). Malaria vaccines-targeting infected hepatocytes. Nature Medicine, 6 (11), 1218-1219. doi: 10.1038/81315 |
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2000 Journal Article HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areasRavichandran, M., Doolan, D. L., Cox-Singh, J., Hoffman, S. L. and Singh, B. (2000). HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. Parasite Immunology, 22 (9), 469-473. doi: 10.1046/j.1365-3024.2000.00324.x |
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2000 Journal Article The complexity of protective immunity against liver-stage malariaDoolan, Denise L. and Hoffman, Stephen L. (2000). The complexity of protective immunity against liver-stage malaria. Journal of Immunology, 165 (3), 1453-1462. doi: 10.4049/jimmunol.165.3.1453 |
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2000 Journal Article HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II allelesDoolan, Denise L., Southwood, Scott, Chesnut, Robert, Appella, Ettore, Gomez, Eduardo, Richards, Allen, Higashimoto, Yuichiro I., Maewal, Ajesh, Sidney, John, Gramzinski, Robert A., Mason, Carl, Koech, Davy, Hoffman, Stephen L. and Sette, Alessandro (2000). HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II alleles. Journal of Immunology, 165 (2), 1123-1137. doi: 10.4049/jimmunol.165.2.1123 |
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2000 Journal Article Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteersLe, T. P., Coonan, K. M., Hedstrom, R. C., Charoenvit, Y., Sedegah, M., Epstein, J. E., Kumar, S., Wang, R., Doolan, D. L., Maguire, J. D., Parker, S. E., Hobart, P., Norman, J. and Hoffman, S. L. (2000). Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers. Vaccine, 18 (18), 1893-1901. doi: 10.1016/s0264-410x(99)00407-7 |
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2000 Journal Article Can malaria DNA vaccines on their own be as immunogenic and protective as prime-boost approaches to immunization?Hoffman, S. L. and Doolan, D. L. (2000). Can malaria DNA vaccines on their own be as immunogenic and protective as prime-boost approaches to immunization?. Developments in biologicals, 104, 121-132. |
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1999 Journal Article IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii modelDoolan, Denise L. and Hoffman, Stephen L. (1999). IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model. Journal of Immunology, 163 (2), 884-892. |
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1999 Journal Article CD4+ T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte proteinCharoenvit, Yupin, Majam, Victoria Fallarme, Corradin, Giampietro, Sacci Jr., John B., Wang, Ruobing, Doolan, Denise L., Jones, Trevor R., Abot, Esteban, Patarroyo, Manuel E., Guzman, Fanny and Hoffman, Stephen L. (1999). CD4+ T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte protein. Infection and Immunity, 67 (11), 5604-5614. doi: 10.1128/iai.67.11.5604-5614.1999 |
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1999 Journal Article Immune effector mechanisms in malariaGood, Michael F. and Doolan, Denise L. (1999). Immune effector mechanisms in malaria. Current Opinion in Immunology, 11 (4), 412-419. doi: 10.1016/S0952-7915(99)80069-7 |
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1998 Journal Article Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccineWang, R, Doolan, D L, Le, T P, Hedstrom, R C, Coonan, K M, Charoenvit, Y, Jones, T R, Hobart, P, Margalith, M, Ng, J, Weiss, W R, Sedegah, M, de Taisne, C, Norman, J A and Hoffman, S L (1998). Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science (New York, N.Y.), 282 (5388), 476-80. doi: 10.1126/science.282.5388.476 |
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1998 Journal Article Simultaneous induction of multiple antigen-specific cytotoxic T lymphocytes in nonhuman primates by immunization with a mixture of four Plasmodium falciparum DNA plasmidsWang, Ruobing, Doolan, Denise L., Charoenvit, Yupin, Hedstrom, Richard C., Gardner, Malcolm J., Hobart, Peter, Tine, John, Sedegah, Martha, Fallarme, Victoria, Sacci Jr., John B., Kaur, Manjit, Klinman, Dennis M., Hoffman, Stephen L. and Weiss, Walter R. (1998). Simultaneous induction of multiple antigen-specific cytotoxic T lymphocytes in nonhuman primates by immunization with a mixture of four Plasmodium falciparum DNA plasmids. Infection and Immunity, 66 (9), 4193-4202. doi: 10.1128/.66.9.4193-4202.1998 |
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1998 Journal Article In vitro expression and in vivo immunogenicity of Plasmodium falciparum pre-erythrocytic stage DNA vaccinesHedstrom, R. C., Doolan, D. L., Wang, R., Kumar, A., Sacci Jr., J. B., Gardner, M. J., Aguiar, J. C., Charoenvit, Y., Sedegah, M., Tine, J. A., Margalith, M., Hobart, P. and Hoffman, S. L. (1998). In vitro expression and in vivo immunogenicity of Plasmodium falciparum pre-erythrocytic stage DNA vaccines. International journal of molecular medicine, 2 (1), 29-38. doi: 10.3892/ijmm.2.1.29 |
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1997 Journal Article DNA vaccination as an approach to malaria control: Current status and strategiesDoolan, D. L., Hedstrom, R. C., Gardner, M. J., Sedegah, M., Wang, H., Gramzinski, R. A., Maroatith, M., Hobart, P. and Hoffman, S. L. (1997). DNA vaccination as an approach to malaria control: Current status and strategies. Current Topics in Microbiology and Immunology, 226, 37-56. |
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1997 Journal Article The development of a multivalent DNA vaccine for malariaHedstrom, Richard C., Doolan, Denise L., Wang, Ruobing, Gardner, Malcolm J., Kumar, Anita, Sedegah, Martha, Gramzinski, Robert A., Sacci Jr., John B., Charoenvit, Yupin, Weiss, Walter R., Margalith, Michal, Norman, Jon A., Hobart, Peter and Hoffman, Stephen L. (1997). The development of a multivalent DNA vaccine for malaria. Springer Seminars in Immunopathology, 19 (2), 147-159. doi: 10.1007/BF00870265 |
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1997 Journal Article DNA vaccines for malaria: The past, the present, and the futureDoolan, Denise L., Hedstrom, Richard C., Wang, Ruobing, Sedegah, Martha, Scheller, Libia F., Hobart, Peter, Norman, Jon A. and Hoffman, Stephen L. (1997). DNA vaccines for malaria: The past, the present, and the future. Indian Journal of Medical Research, 106 (AUG.), 109-119. |
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1997 Conference Publication Malaria DNA vaccines in Aotus monkeysGramzinski, Robert A., Maris, Dorina C., Doolan, Denise, Charoenvit, Yupin, Obaldia, Nicanor, Rossan, Richard, Sedegah, Martha, Wang, Ruobing, Hobart, Peter, Margalith, Michal and Hoffman, Stephen (1997). Malaria DNA vaccines in Aotus monkeys. doi: 10.1016/S0264-410X(96)00270-8 |
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1997 Conference Publication Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human useHoffman, Stephen L., Doolan, Denise L., Sedegah, Martha, Aguiar, Joao C., Wang, Ruobing, Malik, Anita, Gramzinski, Robert A., Weiss, Walter R., Hobart, Peter, Norman, Jon A., Margalith, Michal and Hedstrom, Richard C. (1997). Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human use. doi: 10.1016/S0264-410X(96)00273-3 |
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1997 Journal Article Multi-gene vaccination against malaria: A multistage, multi-immune response approachDoolan, D. L. and Hoffman, S. L. (1997). Multi-gene vaccination against malaria: A multistage, multi-immune response approach. Parasitology Today, 13 (5), 171-178. doi: 10.1016/s0169-4758(97)01040-5 |
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1997 Journal Article Pre-erythrocytic-stage immune effector mechanisms in plasmodium spp. infectionsDoolan, Denise L. and Hoffman, Stephen L. (1997). Pre-erythrocytic-stage immune effector mechanisms in plasmodium spp. infections. Philosophical Transactions of the Royal Society B: Biological Sciences, 352 (1359), 1361-1367. doi: 10.1098/rstb.1997.0121 |
