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2015

Conference Publication

Unexpected activities of the complement pathway in migrating neurons

Reiner, O., Gorelik, A., Sapir, T., Bialas, A. R., Stevens, B., Woodruff, T. M. and Haffner-Krausz, R. (2015). Unexpected activities of the complement pathway in migrating neurons. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13185

Unexpected activities of the complement pathway in migrating neurons

2015

Conference Publication

Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration

Kumar, Vinod, Lee, John, Noakes, Peter and Woodruff, Trent (2015). Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration. 8th International Conference on Complement Therapeutics, Chania, Crete, Greece, 1-6 January 2015.

Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration

2015

Conference Publication

Peripheral immune complement activation in neurodegenerative disease

Mantovani, S., Gordon, R., Ngo, S., Pfluger, C., O'Sullivan, J., Noakes, P., Henderson, R., McCombe, P. and Woodruff, T. (2015). Peripheral immune complement activation in neurodegenerative disease. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/jnc.13188

Peripheral immune complement activation in neurodegenerative disease

2015

Conference Publication

Investigating the role of C5a-CD88 signalling axis in diabetic nephropathy

Tan, S. M., Nguyen, T. V., Woodruff, T. M. and Coughlan, M. T. (2015). Investigating the role of C5a-CD88 signalling axis in diabetic nephropathy. 51st Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Canberra, Australia, 7-9 September, 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12543

Investigating the role of C5a-CD88 signalling axis in diabetic nephropathy

2015

Conference Publication

Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway

Albornoz, E., Deora, V., Robertson, B. A., Cooper, M. A., Schroder, K., Woodruff, T. M. and Gordon, R. (2015). Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley-Blackwell.

Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway

2014

Conference Publication

Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord Injury

Ruitenberg, Marc J., Brennan, Faith H., Gordon, Richard, Blomster, Linda V., Lao, Hong Wa, Cowin, Gary J., Taylor, Stephen M. and Woodruff, Trent M. (2014). Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord Injury. 11th Symposium of the International-Neurotrauma-Society, Budapest, Hungary, 19-23 March 2014. New Rochelle, NY United States: Mary Ann Liebert.

Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord Injury

2014

Conference Publication

Discovery of novel selective C5a2 ligands that can modulate IL-6 releAse from macrophages

Croker, Daniel E., Halai, Reena, Kaeslin, Geraldine, Morikis, Dimitrios, Woodruff, Trent, Floudas, Christodoulos A., Monk, Peter N. and Cooper, Matthew A. (2014). Discovery of novel selective C5a2 ligands that can modulate IL-6 releAse from macrophages. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, Oct 26-29, 2014. London United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.039

Discovery of novel selective C5a2 ligands that can modulate IL-6 releAse from macrophages

2014

Conference Publication

C3a and C5a homeostasis in health and disease

Woodruff, Trent M. (2014). C3a and C5a homeostasis in health and disease. 25th International Complement Workshop, Rio de Janeiro Brazil, 14-18 September 2014. Kidlington, Oxford, United Kingdom: Pergamon Press.

C3a and C5a homeostasis in health and disease

2013

Conference Publication

Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM)

Barrett, Helen L., Mcintyre, H. David, Denny, Kerina, Woodruff, Trent, Callaway, Leonie K. and Nitert, Marloes Dekker (2013). Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM). American Diabetes Association 73rd Scientific Sessions, Chicago, IL United States, 21-25 June 2013 . Arlington, VA United States: American Diabetes Association. doi: 10.2337/db13-1-387

Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM)

2013

Conference Publication

Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease

Mantovani, S., Li, R., Gordon, R., Kumar, V., Taylor, S. and Woodruff, T. M. (2013). Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease. World Congress on Huntington’s disease, Rio de Janeiro, Brazil, 15-18 September 2013. Amsterdam, Netherlands: I O S Press.

Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease

2012

Conference Publication

De novo protein design of agonists and antagonists of C5a receptors

Monkl, Peter N., Bellows-Peterson, Meghan L., Smadbeck, James, Floudas, Christodoulos A., Kieslich, Christopher A., Morikis, Dimitrios and Woodruff, Trent M. (2012). De novo protein design of agonists and antagonists of C5a receptors. 24th International Complement Workshop (ICW), Chania, Crete, Greece, 10-15 October 2012. Jena, Germany: Urban und Fischer Verlag. doi: 10.1016/j.imbio.2012.08.097

De novo protein design of agonists and antagonists of C5a receptors

2012

Conference Publication

The complement receptors CD88, C5L2 and C3AR mediate inflammatory injury following transient cerebral ischemia

Pavlovski, D., Thundyil, J., Taylor, S. M., Arumugam, T., V and Woodruff, T. M. (2012). The complement receptors CD88, C5L2 and C3AR mediate inflammatory injury following transient cerebral ischemia. Stroke 2012 Conference - A combined event of the Stroke Society of Australasia 2012 Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference, Sydney NSW Australia, 29-31 August 2012. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

The complement receptors CD88, C5L2 and C3AR mediate inflammatory injury following transient cerebral ischemia

2012

Conference Publication

Expression of complement factors and functional C5a receptors in human embryonic stem cells, and induced pluripotent stem cells

Hawksworth, Owen A., Coulthard, Liam G., Taylor, Stephen M., Wolvetang, Ernst J. and Woodruff, Trent M. (2012). Expression of complement factors and functional C5a receptors in human embryonic stem cells, and induced pluripotent stem cells. 24th International Complement Workshop (ICW), Chania, Crete, Greece, 10-15 October 2012. Jena, Germany: Urban und Fischer Verlag. doi: 10.1016/j.imbio.2012.08.116

Expression of complement factors and functional C5a receptors in human embryonic stem cells, and induced pluripotent stem cells

2012

Conference Publication

Deficiency of the complement anaphylatoxin receptor C3aR on leukocytes worsens the outcome from spinal cord injury by promoting neutrophilia

Brennan, Faith H., Blomster, Linda V., Costantini, Alexander M., Taylor, Stephen M., Woodruff, Trent M. and Ruitenberg, Marc J. (2012). Deficiency of the complement anaphylatoxin receptor C3aR on leukocytes worsens the outcome from spinal cord injury by promoting neutrophilia. 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, 4-8 November 2012. Amsterdam, The Netherlands: Elsevier.

Deficiency of the complement anaphylatoxin receptor C3aR on leukocytes worsens the outcome from spinal cord injury by promoting neutrophilia

2012

Conference Publication

Antagonizing C5aR reduces T Cell- IL-10-dependent colitis in pre-clinical models

Jain, Umang, Woodruff, Trent and Stadnyk, Andrew (2012). Antagonizing C5aR reduces T Cell- IL-10-dependent colitis in pre-clinical models. 2012 Advances in Inflammatory Bowel Diseases Crohn’s & Colitis Foundation’s National Clinical & Research Conference, Hollywood, Fl, United States, 13-15 December 2012. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1002/ibd.23058

Antagonizing C5aR reduces T Cell- IL-10-dependent colitis in pre-clinical models

2012

Conference Publication

The C3a receptor mediates protection from intestinal ischemia reperfusion injuries by impairing neutrophil mobilization

Woodruff, Trent M., Wu, Mike C. L., Brennan, Faith H., Wetsel, Rick A., Ruitenberg, Marc J. and Taylor, Stephen M. (2012). The C3a receptor mediates protection from intestinal ischemia reperfusion injuries by impairing neutrophil mobilization. 24th International Complement Workshop (ICW), Chania, Crete, Greece, 10-15 October 2012. Jena, Germany: Urban und Fischer Verlag. doi: 10.1016/j.imbio.2012.08.229

The C3a receptor mediates protection from intestinal ischemia reperfusion injuries by impairing neutrophil mobilization

2010

Conference Publication

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

Wu, M. C. L., Moore, T. A., Manthey, H. D., Taylor, S. M. and Woodruff, T. M. (2010). The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.216

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

2010

Conference Publication

C5aR protects against folate-deficiency induced neural tube defects in mice

Costantini, K. J., Coulthard, L. G. J., Lor, Mary, Woodruff, T. M., Callaway, L. K., Finnell, R. H. and Taylor, S. M. (2010). C5aR protects against folate-deficiency induced neural tube defects in mice. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.169

C5aR protects against folate-deficiency induced neural tube defects in mice

2010

Conference Publication

The role of complement-mediated inflammation in miscarriage and preterm birth

Costantini, K. J., Coulthard, L. G., Woodruff, T. M., Taylor, S. M. and Callaway, L. K. (2010). The role of complement-mediated inflammation in miscarriage and preterm birth. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.222

The role of complement-mediated inflammation in miscarriage and preterm birth

2010

Conference Publication

Dysregulation of the complement system in neurodegenerative disease

Woodruff, T. M., Lee, J. D., Taylor, S. M. and Noakes, P. G. (2010). Dysregulation of the complement system in neurodegenerative disease. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.215

Dysregulation of the complement system in neurodegenerative disease