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2020

Journal Article

Regulatory T-cells but not IL-10 impair cell-mediated immunity in HPV+ hyperplastic epithelium

Bashaw, Abate Assefa, Zhou, Chenhao, Yu, Meihua, Tolley, Lynn, Leggatt, Graham R., Frazer, Ian H. and Chandra, Janin (2020). Regulatory T-cells but not IL-10 impair cell-mediated immunity in HPV+ hyperplastic epithelium. The Journal of Investigative Dermatology, 141 (5), 1264-1273.e3. doi: 10.1016/j.jid.2020.10.011

Regulatory T-cells but not IL-10 impair cell-mediated immunity in HPV+ hyperplastic epithelium

2020

Conference Publication

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

Leggatt, Graham R., Salim, Nazhifah and Mattarollo, Stephen (2020). Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.165.27

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

2020

Conference Publication

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

Wright, Quentin, Minnie, Simone and Leggatt, Graham R. (2020). Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.241.23

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

2020

Conference Publication

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

Leggatt, Graham R., Salim, Nazhifah and Mattarollo, Stephen (2020). Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin. IMMUNOLOGY2020, Honolulu, HI, United States, 8-12 May, 2020. Rockville, MD, United States: American Association of Immunologists.

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin

2020

Journal Article

Serum antibodies against Toxoplasma gondii and Neospora caninum in southeast Queensland dugongs

Wong, Arthur, Lanyon, Janet M., O'Handley, Ryan, Linedale, Richard, Woolford, Lucy, Long, Trevor and Leggatt, Graham R. (2020). Serum antibodies against Toxoplasma gondii and Neospora caninum in southeast Queensland dugongs. Marine Mammal Science, 36 (1) mms.12629, 180-194. doi: 10.1111/mms.12629

Serum antibodies against Toxoplasma gondii and Neospora caninum in southeast Queensland dugongs

2020

Conference Publication

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

Wright, Quentin, Minnie, Simone and Leggatt, Graham R. (2020). Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis. IMMUNOLOGY2020, Honolulu, HI, United States, 8-12 May 2020. Rockville, MD, United States: American Association of Immunologists.

Intradermal delivery of a combination of immunomodulatory antibodies can promote rejection of hyperplastic skin in a mouse model of actinic keratosis

2019

Journal Article

HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T cell development

Bashaw, Abate Assefa, Teoh, Siok M., Tuong, Zewen K., Leggatt, Graham R., Frazer, Ian H. and Chandra, Janin (2019). HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T cell development. Journal of Investigative Dermatology, 139 (12), 2467-2476.e3. doi: 10.1016/j.jid.2019.03.1162

HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T cell development

2019

Journal Article

Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage

Tuong, Zewen, Lewandowski, Andrew, Bridge, Jennifer, Gonzalez-Cruz, Jazmina, Yamada, Miko, Lambie, Duncan, Lewandowski, Richard, Steptoe, Raymond, Leggatt, Graham, Simpson, Fiona, Frazer, Ian, Soyer, Peter and Wells, James W. (2019). Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage. Scientific Reports, 9 (1) 17754, 17754. doi: 10.1038/s41598-019-54435-0

Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage

2019

Journal Article

NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion

Lam, Pui Yeng, Kobayashi, Takumi, Soon, Megan, Zeng, Bijun, Dolcetti, Riccardo, Leggatt, Graham, Thomas, Ranjeny and Mattarollo, Stephen R. (2019). NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion. Cancer Immunology Research, 7 (6), 952-962. doi: 10.1158/2326-6066.cir-18-0650

NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion

2018

Journal Article

Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction

Kuo, Paula, Teoh, Siok Min, Tuong, Zewen K., Leggatt, Graham R., Mattarollo, Stephen R. and Frazer, Ian H. (2018). Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction. Frontiers in Immunology, 9 2896, 2896. doi: 10.3389/fimmu.2018.02896

Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction

2018

Journal Article

The role of CXCR3 and its chemokine ligands in skin disease and cancer

Kuo, Paula T., Zeng, Zhen, Salim, Nazhifah, Mattarollo, Stephen, Wells, James W. and Leggatt, Graham R. (2018). The role of CXCR3 and its chemokine ligands in skin disease and cancer. Frontiers in Medicine, 5 (SEP) 271, 271. doi: 10.3389/fmed.2018.00271

The role of CXCR3 and its chemokine ligands in skin disease and cancer

2018

Journal Article

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

Joseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018). An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, 139 (1), 213-223. doi: 10.1016/j.jid.2018.06.190

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

2018

Journal Article

Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia

Kerage, Daniel, Soon, Megan S. F., Doff, Brianna L., Kobayashi, Takumi, Nissen, Michael D., Lam, Pui Yeng, Leggatt, Graham R. and Mattarollo, Stephen R. (2018). Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia. OncoImmunology, 7 (10) e1486952, 1-10. doi: 10.1080/2162402x.2018.1486952

Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia

2018

Journal Article

Development of a polyclonal anti-dugong immunoglobulin G (IgG) antibody with evaluation of total plasma IgG in a living dugong (Dugong dugon) population

Wong, Arthur, Lanyon, Janet M., McKee, Sara J., Linedale, Richard, Woolford, Lucy, Long, Trevor and Leggatt, Graham R. (2018). Development of a polyclonal anti-dugong immunoglobulin G (IgG) antibody with evaluation of total plasma IgG in a living dugong (Dugong dugon) population. Veterinary Immunology and Immunopathology, 200, 16-25. doi: 10.1016/j.vetimm.2018.04.003

Development of a polyclonal anti-dugong immunoglobulin G (IgG) antibody with evaluation of total plasma IgG in a living dugong (Dugong dugon) population

2018

Journal Article

Comparison of i-STAT® with traditional laboratory analysers in the measurement of blood analytes from field captured dugongs (Dugong dugon)

Wong, Arthur W., Lanyon, Janet M., Sneath, Helen L., Leggatt, Graham R. and Woolford, Lucy (2018). Comparison of i-STAT® with traditional laboratory analysers in the measurement of blood analytes from field captured dugongs (Dugong dugon). Aquatic Mammals, 44 (1), 19-31. doi: 10.1578/AM.44.1.2018.19

Comparison of i-STAT® with traditional laboratory analysers in the measurement of blood analytes from field captured dugongs (Dugong dugon)

2018

Journal Article

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity

McKee, Sara J., Tuong, Zewen K., Kobayashi, Takumi, Doff, Brianna L., Soon, Megan S. F ., Nissen, Michael, Lam, Pui Yeng, Keane, Colm, Vari, Frank, Moi, Davide, Mazzieri, Roberta, Leggatt, Graham, Gandhi, Maher K. and Mattarollo, Stephen R. (2018). B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity. OncoImmunology, 7 (2) e1393599, e1393599. doi: 10.1080/2162402X.2017.1393599

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity

2017

Journal Article

Modulation of antigen presenting cell functions during chronic HPV infection

Bashaw, Abate Assefa, Leggatt, Graham R., Chandra, Janin, Tuong, Zewen K. and Frazer, Ian H. (2017). Modulation of antigen presenting cell functions during chronic HPV infection. Papillomavirus Research, 4, 58-65. doi: 10.1016/j.pvr.2017.08.002

Modulation of antigen presenting cell functions during chronic HPV infection

2017

Journal Article

Interferon-gamma derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

Bhat, Purnima, Leggatt, Graham, Waterhouse, Nigel and Frazer, Ian H. (2017). Interferon-gamma derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity. Cell Death and Disease, 8 (6) e2836, e2836.1-e2836.11. doi: 10.1038/cddis.2017.67

Interferon-gamma derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

2017

Journal Article

HPV16-E7-specific activated CD8 T cells in E7 transgenic skin and skin grafts

Jazayeri, Seyed D., Kuo, Paula, Leggatt, Graham R. and Frazer, Ian (2017). HPV16-E7-specific activated CD8 T cells in E7 transgenic skin and skin grafts. Frontiers in Immunology, 8 (MAY) 524, 524. doi: 10.3389/fimmu.2017.00524

HPV16-E7-specific activated CD8 T cells in E7 transgenic skin and skin grafts

2017

Journal Article

Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients

Linedale, Richard, Schmidt, Campbell, King, Brigid T., Ganko, Annabelle G., Simpson, Fiona, Panizza, Benedict J. and Graham R. Leggatt (2017). Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients. PLoS One, 12 (4) e0175755, e0175755.1-e0175755.13. doi: 10.1371/journal.pone.0175755

Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients