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2009 Conference Publication RNA interference for the treatment of cervical cancers: Solving the delivery and efficacy issuesGu, W. Y., Leggatt, G., Payne, E., Wilson, D., Choyce, A. and McMillan, N. A. J. (2009). RNA interference for the treatment of cervical cancers: Solving the delivery and efficacy issues. 6th Meeting of the Australasian Gene Therapy Society, Sydney, Australia, 29 April - 01 May 2009. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/jgm.1375 |
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2009 Conference Publication Immunotherapy for skin cancerLeggatt, G. R., Zhong, J., Mattarollo, S., Liu, X., De Kluyver, R., Fiorenza, S., Zhou, J., Hadis, U., Warif, N. A., Rahimpour, A., Broom, J. and Frazer, I. H. (2009). Immunotherapy for skin cancer. 6th Annual Scientific Meeting, Australasian Society for Dermatology Research, Surfers Paradise, QLD, Australia, 20-21 May 2009. Baltimore, MD, U.S.A.: Nature Publishing Group. doi: 10.1038/jid.2009.333 |
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2008 Journal Article TLR7 stimulation augments T effector-mediated rejection, of skin expressing neo-self antigen in keratinocytesZhong, Jie, Usriansyah Usriansyah, Rachel De Kluyver, Leggatt, Graham R., Fernando, Germain J. and Frazer, Ian H. (2008). TLR7 stimulation augments T effector-mediated rejection, of skin expressing neo-self antigen in keratinocytes. European Journal of Immunology, 38 (1), 73-81. doi: 10.1002/eji.200737599 |
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2007 Journal Article HPV vaccines: the beginning of the end for cervical cancerLeggatt, G. R. and Frazer, I. H. (2007). HPV vaccines: the beginning of the end for cervical cancer. Current Opinion In Immunology, 19 (2), 232-238. doi: 10.1016/j.coi.2007.01.004 |
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2006 Journal Article Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenesGu, W., Putral, L., Hengst, K., Minto, K., Saunders, N. A., Leggatt, G. and McMillan, N. A. J. (2006). Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes. Cancer Gene Therapy, 13 (11), 1023-1032. doi: 10.1038/sj.cgt.7700971 |
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2006 Journal Article Overcoming original antigenic sin to generate new CD8 T cell IFN-gamma responses in an antigen-experienced hostLiu, Xiao Song, Dyer, Joanne, Leggatt, Graham R., Fernando, Germain J. P., Zhong, Jie, Thomas, Ranjeny and Frazer, Ian H. (2006). Overcoming original antigenic sin to generate new CD8 T cell IFN-gamma responses in an antigen-experienced host. Journal of Immunology, 177 (5), 2873-2879. doi: 10.4049/jimmunol.177.5.2873 |
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2005 Journal Article Apoptosis mediated by CD8+T cells targeted to endogenous antigens in transgenic keratinocytesZhou, F., Leggatt, G., Zhong, J., Zhao, K., De Kluyver, R. and Frazer, I. H. (2005). Apoptosis mediated by CD8+T cells targeted to endogenous antigens in transgenic keratinocytes. Tissue Antigens, 66 (5), 600-600. doi: 10.1111/j.1399-0039.2005.00523.x |
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2005 Journal Article The role of CD4 T help in multiple vaccinations when using minimal CD8 T cell epitope peptidesKhammanivong, V., Peters, T., Andrews, M., Leggatt, G. R., Frazer, I. H. and Fernando, G. J. (2005). The role of CD4 T help in multiple vaccinations when using minimal CD8 T cell epitope peptides. Tissue Antigens, 66 (5), 415-415. |
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2005 Journal Article A model of peripheral CD8(+) T cell tolerance against skin antigenNarayan, S., Fernando, G., Frazer, I. H. and Leggatt, G. (2005). A model of peripheral CD8(+) T cell tolerance against skin antigen. Tissue Antigens, 66 (5), 501-501. doi: 10.1111/j.1399-0039.2005.00523.x |
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2005 Journal Article Transgenic expression of a viral oncoprotein exclusively in K14(+) epithelial cells results in peripheral but not central CD8 T cell toleranceLeggatt, G. R., Saunders, N., Dahler, A., Fernando, G. J., Matsumoto, K., Narayan, S., Linedale, R., Choyce, A. and Frazer, I. H. (2005). Transgenic expression of a viral oncoprotein exclusively in K14(+) epithelial cells results in peripheral but not central CD8 T cell tolerance. Tissue Antigens, 66 (5), 475-476. |
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2005 Journal Article Local inflammation is crucial for T cell mediated rejection of skin graft expressing foreign antigenZhong, J., De Kluyver, R., Leggatt, G. R., Fernando, G. J. and Frazer, I. H. (2005). Local inflammation is crucial for T cell mediated rejection of skin graft expressing foreign antigen. Tissue Antigens, 66 (5), 600-600. |
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2005 Journal Article Interferon-gamma is required for killing keratinocytes in vitro and in vivoDe Kluyver, R. L., Morritz, L., Leggatt, G. R., Harris, C., Lambert, P. F. and Frazer, I. H. (2005). Interferon-gamma is required for killing keratinocytes in vitro and in vivo. Tissue Antigens, 66 (5), 394-394. |
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2005 Journal Article Overcoming original antigenic sin to generate effective immune responses in antigen primed hostLiu, X., Leggatt, G., Fernando, G. J. and Frazer, I. H. (2005). Overcoming original antigenic sin to generate effective immune responses in antigen primed host. Tissue Antigens, 66 (5), 481-481. |
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2005 Journal Article RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatinPutral, L. N., Bywater, M. J., Gu, W. Y., Saunders, N. A., Gabrielli, B. G., Leggatt, G. R. and McMillan, N. A. J. (2005). RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin. Molecular Pharmacology, 68 (5), 1311-1319. doi: 10.1124/mol.105.014191 |
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2004 Journal Article Functional memory CD8+ T cells can be generated in vivo without evident T helpAndrews, Melanie R., Peters, Tania, Khammanivong, Vithagna, Leggatt, Graham R., Frazer, Ian H. and Fernando, Germain J. P. (2004). Functional memory CD8+ T cells can be generated in vivo without evident T help. Vaccine, 23 (6), 739-742. doi: 10.1016/j.vaccine.2004.07.027 |
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2004 Journal Article Human growth hormone (hGH) presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejectionZhong, J., Matsumoto, K., De Kluyver, R., Fernando, G. J. P., Leggatt, G. R. and Frazer, I. H. (2004). Human growth hormone (hGH) presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection. Journal of Investigative Dermatology, 123 (6), A113-A113. |
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2004 Journal Article Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytesLeggatt, Graham R., Narayan, Sharmal, Fernando, Germain J. P. and Frazer, Ian H. (2004). Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytes. Journal of Leukocyte Biology, 76 (4), 787-795. doi: 10.1189/jlb.0104026 |
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2004 Journal Article Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturationStewart, Trina J., Fernando, Germain J. P., Frazer, Ian H. and Leggatt, Graham R. (2004). Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturation. Immunology and Cell Biology, 82 (5), 455-461. doi: 10.1111/j.0818-9641.2004.01273.x |
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2004 Journal Article Human growth hormone presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejectionZhong, Jie, Matsumoto, Koji, De Kluyver, Rachel, Fernando, Germain J. P., Leggatt, Graham R. and Frazer, Ian H. (2004). Human growth hormone presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection. Immunology and Cell Biology, 82 (6), 577-586. doi: 10.1111/j.1440-1711.2004.01292.x |
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2004 Journal Article Erratum: IL-10 Mediates Suppression of the CD8 T Cell IFN-γ Response to a Novel Viral Epitope in a Primed Host (Journal of Immunology (2003) 171 (4765-4772))Liu, X. S., Xu, Y., Zhao, W. M., Fernando, G. J. P., Leggatt, G. R. and Frazer, I. H. (2004). Erratum: IL-10 Mediates Suppression of the CD8 T Cell IFN-γ Response to a Novel Viral Epitope in a Primed Host (Journal of Immunology (2003) 171 (4765-4772)). Journal of Immunology, 172 (2), 1311-1311. doi: 10.4049/jimmunol.172.2.1311-a |