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2016

Conference Publication

Characterising the effects of interferon lambda on dendritic cells

Pang, E. S., Macri, C., Pooley, J., Fancke, B., Lundie, R., Hochrein, H., Radford, K. and O'Keeffe, M. (2016). Characterising the effects of interferon lambda on dendritic cells. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.

Characterising the effects of interferon lambda on dendritic cells

2015

Journal Article

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

Beringer, Dennis X., Kleijwegt, Fleur S., Wiede, Florian, Van Der Slik, Arno R., Loh, Khai Lee, Petersen, Jan, Dudek, Nadine L., Duinkerken, Gaby, Laban, Sandra, Joosten, Antoinette, Vivian, Julian P., Chen, Zhenjun, Uldrich, Anthony W., Godfrey, Dale I., McCluskey, James, Price, David A., Radford, Kristen J., Purcell, Anthony W., Nikolic, Tatjana, Reid, Hugh H., Tiganis, Tony, Roep, Bart O. and Rossjohn, Jamie (2015). T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nature Immunology, 16 (11), 1153-1161. doi: 10.1038/ni.3271

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

2015

Journal Article

Human dendritic cell subsets and function in health and disease

O'Keeffe, Meredith., Mok, Wai Hong. and Radford, Kristen J. (2015). Human dendritic cell subsets and function in health and disease. Cellular and Molecular Life Sciences, 72 (22), 4309-4325. doi: 10.1007/s00018-015-2005-0

Human dendritic cell subsets and function in health and disease

2015

Journal Article

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

Mintern, Justine D., Macri, Christophe, Chin, Wei Jin, Panozza, Scott E., Segura, Elodie, Patterson, Natalie L., Zeller, Peter, Bourges, Dorothee, Bedoui, Sammy, McMillan, Paul J., Idris, Adi, Nowell, Cameron J., Brown, Andrew, Radford, Kristen J., Johnston, Angus P. R. and Villadangos, Jose A. (2015). Differential use of autophagy by primary dendritic cells specialized in cross-presentation. Autophagy, 11 (6), 906-917. doi: 10.1080/15548627.2015.1045178

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

2015

Journal Article

A phase I clinical trial of CD1c (BDCA-1)+ dendritic cells pulsed with HLA-A*0201 peptides for immunotherapy of metastatic hormone refractory prostate cancer

Prue, Rebecca L., Vari, Frank, Radford, Kristen J., Tong, Hui, Hardy, Melinda Y., D'Rozario, Rachael, Waterhouse, Nigel J., Rossetti, Tony, Coleman, Robert, Tracey, Christopher, Goossen, Hans, Gounder, Vinay, Crosbie, Georgina, Hancock, Sonia, Diaz-Guilas, Stephanie, Mainwaring, Paul, Swindle, Peter and Hart, Derek N. J. (2015). A phase I clinical trial of CD1c (BDCA-1)+ dendritic cells pulsed with HLA-A*0201 peptides for immunotherapy of metastatic hormone refractory prostate cancer. Journal of Immunotherapy, 38 (2), 71-76. doi: 10.1097/CJI.0000000000000063

A phase I clinical trial of CD1c (BDCA-1)+ dendritic cells pulsed with HLA-A*0201 peptides for immunotherapy of metastatic hormone refractory prostate cancer

2015

Conference Publication

Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade

Winkler, Ingrid G., Barbier, Valerie, Radford, Kristen J., Davies, Julie M., Levesque, Jean-Pierre, Smith, Theodore A. G., Fogler, William E. and Magnani, John L. (2015). Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade. 57th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 5-8 December 2015. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V126.23.512.512

Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade

2015

Journal Article

Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets

Chiang, Meng-Chieh, Tullett, Kirsteen M., Lee, Yoke Seng, Idris, Adi, Ding, Yitian, McDonald, Kylie J., Kassianos, Andrew, Leal Rojas, Ingrid M., Jeet, Varinder, Lahoud, Mireille H. and Radford, Kristen J. (2015). Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets. European Journal of Immunology, 46 (2), 329-339. doi: 10.1002/eji.201546023

Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets

2014

Journal Article

Harnessing human cross-presenting CLEC9A+XCR1+ dendritic cells for immunotherapy

Tullett, Kirsteen M., Lahoud, Mireille H. and Radford, Kristen J. (2014). Harnessing human cross-presenting CLEC9A+XCR1+ dendritic cells for immunotherapy. Frontiers in Immunology, 5 (MAY) Article 239, 1-1. doi: 10.3389/fimmu.2014.00239

Harnessing human cross-presenting CLEC9A+XCR1+ dendritic cells for immunotherapy

2014

Journal Article

Dendritic cells and cancer immunotherapy

Radford, Kristen J., Tullett, Kirsteen M. and Lahoud, Mireille H. (2014). Dendritic cells and cancer immunotherapy. Current Opinion in Immunology, 27 (1), 26-32. doi: 10.1016/j.coi.2014.01.005

Dendritic cells and cancer immunotherapy

2014

Journal Article

FLT3-ligand treatment of humanized mice results in the generation of large numbers of CD141+ and CD1c+ dendritic cells in vivo

Ding, Yitian, Wilkinson, Andrew, Idris, Adi, Fancke, Ben, O’Keeffe, Meredith, Khalil, Dalia, Ju, Xinsheng, Lahoud, Mireille H., Caminschi, Irina, Shortman, Ken, Rodwell, Robyn, Vuckovic, Slavica and Radford, Kristen J. (2014). FLT3-ligand treatment of humanized mice results in the generation of large numbers of CD141+ and CD1c+ dendritic cells in vivo. Journal of Immunology. doi: 10.4049/jimmunol.1302391

FLT3-ligand treatment of humanized mice results in the generation of large numbers of CD141+ and CD1c+ dendritic cells in vivo

2013

Journal Article

New generation of dendritic cell vaccines

Radford, Kristen J. and Caminschi, Irina (2013). New generation of dendritic cell vaccines. Human Vaccines and Immunotherapeutics, 9 (2), 259-264. doi: 10.4161/hv.22487

New generation of dendritic cell vaccines

2013

Book Chapter

Dendritic cells in autoimmune disease

Radford, Kristen J., Shortman, Ken and O'Keefe, Meredith (2013). Dendritic cells in autoimmune disease. The autoimmune diseases. (pp. 175-186) edited by Noel R. Rose and Ian R. Mackay. San Diego, United States: Elsevier. doi: 10.1016/B978-0-12-384929-8.00012-5

Dendritic cells in autoimmune disease

2012

Journal Article

Mincle polarizes human monocyte and neutrophil responses to Candida albicans

Vijayan, Dipti, Radford, Kristen J., Beckhouse, Anthony G., Ashman, Robert B. and Wells, Christine A. (2012). Mincle polarizes human monocyte and neutrophil responses to Candida albicans. Immunology and Cell Biology, 90 (9), 889-895. doi: 10.1038/icb.2012.24

Mincle polarizes human monocyte and neutrophil responses to Candida albicans

2012

Journal Article

Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli

Kassianos, Andrew J., Hardy, Melinda Y., Ju, Xinsheng, Vijayan, Dipti, Ding, Yitian, Vulink, Annelie J. E., McDonald, Kylie J., Jongbloed, Sarah L., Wadley, Robert B., Wells, Christine, Hart, Derek N. J. and Radford, Kristen J. (2012). Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli. European Journal of Immunology, 42 (6), 1512-1522. doi: 10.1002/eji.201142098

Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli

2012

Journal Article

Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients

Wilkinson, Ray, Woods, Katherine, D’Rozario, Rachael, Prue, Rebecca, Vari, Frank, Hardy, Melinda Y., Dong, Ying, Clements, Judith A., Hart, Derek N.J. and Radford, Kristen J. (2012). Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients. Cancer Immunology, Immunotherapy, 61 (2), 169-179. doi: 10.1007/s00262-011-1095-2

Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients

2011

Journal Article

CD34+ cord blood DC-induced antitumor lymphoid cells have efficacy in a murine xenograft model of human ALL

Cullup, Hannah, Hsu, Andy K. W., Kassianos, Andrew J., McDonald, Kylie, Radford, Kristen J. and Rice, Alison M. (2011). CD34+ cord blood DC-induced antitumor lymphoid cells have efficacy in a murine xenograft model of human ALL. Journal of Immunotherapy, 34 (4), 362-371. doi: 10.1097/CJI.0b013e31821b7230

CD34+ cord blood DC-induced antitumor lymphoid cells have efficacy in a murine xenograft model of human ALL

2011

Conference Publication

Monocytes Are Associated with Impaired T-Cell Immunity and Residual Interim-PET/CT Avidity After 4 Cycles of CHOP-R In Patients with High-Risk DLBCL

Gandhi, MK, Hertzberg, MS, Han, E, Seymour, JF, Hicks, R, Gill, DS, Keane, C, Crooks, P, Radford, K and Vari, F (2011). Monocytes Are Associated with Impaired T-Cell Immunity and Residual Interim-PET/CT Avidity After 4 Cycles of CHOP-R In Patients with High-Risk DLBCL. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego Ca, Dec 10-13, 2011. WASHINGTON: AMER SOC HEMATOLOGY.

Monocytes Are Associated with Impaired T-Cell Immunity and Residual Interim-PET/CT Avidity After 4 Cycles of CHOP-R In Patients with High-Risk DLBCL

2010

Journal Article

Human CD141(+) (BDCA-3)(+) dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

Jongbloed, Sarah L., Kassianos, Andrew J., McDonald, Kylie J., Clark, Georgina J., Ju, Xinsheng, Angel, Catherine E., Chen, Chun-Jen J., Dunbar, P. Rod, Wadley, obert B., Jeet, Varinder, Vulink, Annelie J.E., Hart, Derek N.J. and Radford, Kristen J. (2010). Human CD141(+) (BDCA-3)(+) dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. Journal of Experimental Medicine, 207 (6), 1247-1260. doi: 10.1084/jem.20092140

Human CD141(+) (BDCA-3)(+) dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

2010

Book Chapter

Isolation of Human Blood DC Subtypes

Kassianos, Andrew J., Jongbloed, Sarah L., Hart, Derek N.J. and Radford, Kristen J. (2010). Isolation of Human Blood DC Subtypes. Dendritic cell protocols. (pp. 45-54) edited by Shalin H. Naik. New York, NY United States: Humana Press. doi: 10.1007/978-1-60761-421-0_3

Isolation of Human Blood DC Subtypes

2009

Journal Article

NK cells enhance the induction of CTL responses by IL-15 monocyte-derived dendritic cells

Hardy, M., Kassianos, A., Vulink, A., Wilkinson, R., Jongbloed, S. L., Hart, D. N. J. and Radford, K. J. (2009). NK cells enhance the induction of CTL responses by IL-15 monocyte-derived dendritic cells. Immunology and Cell Biology, 87 (8), 606-614. doi: 10.1038/icb.2009.44

NK cells enhance the induction of CTL responses by IL-15 monocyte-derived dendritic cells