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2020 Journal Article RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cellsTullett, Kirsteen M., Tan, Peck Szee, Park, Hae-Young, Schittenhelm, Ralf B., Michael, Nicole, Li, Rong, Policheni, Antonia N., Gruber, Emily, Huang, Cheng, Fulcher, Alex J., Danne, Jillian C., Czabotar, Peter E., Wakim, Linda M., Mintern, Justine D., Ramm, Georg, Radford, Kristen J., Caminschi, Irina, O'Keeffe, Meredith, Villadangos, Jose A., Wright, Mark D., Blewitt, Marnie E., Heath, William R., Shortman, Ken, Purcell, Anthony W., Nicola, Nicos A., Zhang, Jian-Guo and Lahoud, Mireille H. (2020). RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells. eLife, 9 e63452, 1-31. doi: 10.7554/eLife.63452 |
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2020 Journal Article Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate naïve and memory NY-ESO-1-specific CD8+ T cellsMasterman, Kelly-Anne, Haigh, Oscar L., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Walpole, Carina, Pearson, Frances E., Cebon, Jonathon, Schmidt, Christopher, O'Brien, Liam, Rosendahl, Nikita, Daraj, Ghazal, Caminschi, Irina, Gschweng, Eric H., Hollis, Roger P., Kohn, Donald B., Lahoud, Mireille H. and Radford, Kristen J. (2020). Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate naïve and memory NY-ESO-1-specific CD8+ T cells. Journal for ImmunoTherapy of Cancer, 8 (2) e000691, 1-11. doi: 10.1136/jitc-2020-000691 |
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2020 Journal Article Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1-specific CD8+ T cellsPearson, Frances E., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Haigh, Oscar L., Masterman, Kelly-Anne, Walpole, Carina, Bridgeman, John S., McLaren, James E., Ladell, Kristin, Miners, Kelly, Llewellyn-Lacey, Sian, Price, David A., Tunger, Antje, Schmitz, Marc, Miles, John J., Lahoud, Mireille H. and Radford, Kristen J. (2020). Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1-specific CD8+ T cells. Clinical and Translational Immunology, 9 (6) e1141, e1141. doi: 10.1002/cti2.1141 |
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2020 Journal Article Abstract B42: Human CD141+ dendritic cells (cDC1) are impaired in advanced melanoma patients but can be targeted to increase efficacy of anti-PD-1 checkpoint inhibitor therapyO’Brien, Liam, Lee, Yoke Seng, Walpole, Carina, Rojas, Ingrid Leal, Masterman, Kelly-Anne, Atkinson, Victoria, Barbour, Andrew and Radford, Kristen (2020). Abstract B42: Human CD141+ dendritic cells (cDC1) are impaired in advanced melanoma patients but can be targeted to increase efficacy of anti-PD-1 checkpoint inhibitor therapy. Cancer Immunology Research, 8 (3_Supplement). doi: 10.1158/2326-6074.tumimm19-b42 |
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2020 Book Chapter Unexplored horizons of cDC1 in immunity and toleranceBalan, Sreekumar, Radford, Kristen J. and Bhardwaj, Nina (2020). Unexplored horizons of cDC1 in immunity and tolerance. Advances in Immunology. (pp. 49-91) San Diego, CA United States: Academic Press. doi: 10.1016/bs.ai.2020.10.002 |
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2019 Journal Article MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activitySheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y |
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2019 Journal Article Can Dendritic Cell vaccination prevent leukemia relapse?O’Brien, Liam J., Guillerey, Camille and Radford, Kristen J. (2019). Can Dendritic Cell vaccination prevent leukemia relapse?. Cancers, 11 (6) 875, 875. doi: 10.3390/cancers11060875 |
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2019 Journal Article Simple, rapid and inexpensive typing of common HLA class I alleles for immunological studiesLaw, Soi Cheng, Haigh, Oscar L., Walpole, Carina M., Keane, Colm, Miles, John, Gandhi, Maher K., Radford, Kristen J. and Steptoe, Raymond J. (2019). Simple, rapid and inexpensive typing of common HLA class I alleles for immunological studies. Journal of Immunological Methods, 465, 72-76. doi: 10.1016/j.jim.2018.12.002 |
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2019 Book Chapter Monitoring dendritic cell activation and maturationMacri, Christophe, Fancke, Ben, Radford, Kristen J. and O’Keeffe, Meredith (2019). Monitoring dendritic cell activation and maturation. Antigen Processing. (pp. 403-418) edited by Peter van Endert. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-9450-2_28 |
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2019 Book Chapter The role of dendritic cells in cancerLee, Yoke Seng and Radford, Kristen J. (2019). The role of dendritic cells in cancer. Immunobiology of Dendritic Cells. Part A. (pp. 123-178) edited by Claire Lhuillier and Lorenzo Galluzzi. Cambridge, MA, United States: Academic Press. doi: 10.1016/bs.ircmb.2019.07.006 |
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2018 Conference Publication Targeting human CD141+DC using CLEC9A antibodies for cancer immunotherapyMasterman, K-A., Pearson, F. E., Tullett, K., Haigh, O., Walpole, C., Daraj, G., Lahoud, M. H., Rojas, I. Leal and Radford, K. (2018). Targeting human CD141+DC using CLEC9A antibodies for cancer immunotherapy. ESMO Immuno-Oncology Congress, Geneva Switzerland, Dec 13-16, 2018. OXFORD: OXFORD UNIV PRESS. |
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2018 Conference Publication Characterising the effects of interferon lambda on dendritic cell function and activationPang, E. S., Macri, C., Lundie, R., Pooley, J., Gearing, J., Pupovac, A., Jacobson, K., Hertzog, P., Hochrein, H., Radford, K. and O'Keeffe, M. (2018). Characterising the effects of interferon lambda on dendritic cell function and activation. 15th International Symposium on Dendritic Cells (DC), Aachen Germany, Jun 10-14, 2018. HOBOKEN: WILEY. |
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2018 Journal Article Activation of human CD141+ and CD1c+ dendritic cells in vivo with combined TLR 3 and TLR 7/8 ligationPearson, Frances E., Chang, Karshing, Minoda, Yoshihito, Leal Rojas, Ingrid M., Haigh, Oscar L., Daraj, Ghazal, Tullett, Kirsteen M. and Radford, Kristen J. (2018). Activation of human CD141+ and CD1c+ dendritic cells in vivo with combined TLR 3 and TLR 7/8 ligation. Immunology and Cell Biology, 96 (4), 390-400. doi: 10.1111/imcb.12009 |
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2018 Conference Publication Targeting human CD141(+) DC using CLEC9A antibodies for cancer immunotherapyPearson, F., Masterman, K. A., Tullett, K., Haigh, O., Walpole, C., Daraj, G., Rojas, Leal, Lahoud, M. H. and Radford, K. (2018). Targeting human CD141(+) DC using CLEC9A antibodies for cancer immunotherapy. 15th International Symposium on Dendritic Cells (DC), Aachen Germany, Jun 10-14, 2018. Hoboken, NJ United States: Wiley. |
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2017 Journal Article Human CD141(+) dendritic cell and CD1c(+) dendritic cell undergo concordant early genetic programming after activation in humanized mice in vivoMinoda, Yoshihito, Virshup, Isaac, Rojas, Ingrid Leal, Haigh, Oscar, Wong, Yide, Miles, John J., Wells, Christine A. and Radford, Kristen J. (2017). Human CD141(+) dendritic cell and CD1c(+) dendritic cell undergo concordant early genetic programming after activation in humanized mice in vivo. Frontiers in Immunology, 8 (OCT) 1419, 1419. doi: 10.3389/fimmu.2017.01419 |
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2017 Journal Article Human blood cD1c+ dendritic cells promote Th1 and Th17 effector function in memory cD4+ T cellsRojas, Ingrid M. Leal, Mok, Wai-Hong, Pearson, Frances E., Minoda, Yoshihito, Kenna, Tony J., Barnard, Ross T. and Radford, Kristen J. (2017). Human blood cD1c+ dendritic cells promote Th1 and Th17 effector function in memory cD4+ T cells. Frontiers in Immunology, 8 (AUG) 971, 971. doi: 10.3389/fimmu.2017.00971 |
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2016 Journal Article Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+ T cell recognitionTullett, Kirsteen M., Leal Rojas, Ingrid M., Minoda, Yoshihito, Tan, Peck S., Zhang, Jian-Guo, Smith, Corey, Khanna, Rajiv, Shortman, Ken, Caminschi, Irina, Lahoud, Mireille H. and Radford, Kristen J. (2016). Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+ T cell recognition. JCI Insight, 1 (7) e87102, e87102. doi: 10.1172/jci.insight.87102 |
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2016 Conference Publication Human dendritic cell interactions with P-falciparum provide insight into the development of host immunity to malariaYap, X. Z., Lundie, R. J., Macri, C. F., Rojas, Leal, I, Feng, G., Radford, K. J., Beeson, J. G. and O'Keeffe, M. (2016). Human dendritic cell interactions with P-falciparum provide insight into the development of host immunity to malaria. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Characterising the effects of interferon lambda on dendritic cellsPang, E. S., Macri, C., Pooley, J., Fancke, B., Lundie, R., Hochrein, H., Radford, K. and O'Keeffe, M. (2016). Characterising the effects of interferon lambda on dendritic cells. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Targeting CLEC9A can deliver antigen to human CD141(+) DC for recognition by both CD4(+) and CD8(+) T cellsTullett, K. M., Leal Rojas, I. M., Minoda, Y., Tan, P. S., Zhang, J. -G, Smith, C., Khanna, R., Shortman, K., Caminschi, I, Lahoud, M. H. and Radford, K. J. (2016). Targeting CLEC9A can deliver antigen to human CD141(+) DC for recognition by both CD4(+) and CD8(+) T cells. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August, 2016. Weinheim, Germany: Wiley. |
