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2024 Journal Article Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systemsGillespie, Ellen R., Grice, Laura F., Courtney, Isabel G., Lao, Hong Wa, Jung, Woncheol, Ramkomuth, Sonny, Xie, Jacky, Brown, David A., Walsham, James, Radford, Kristen J., Nguyen, Quan H. and Ruitenberg, Marc J. (2024). Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems. Journal of Neuroinflammation, 21 (1) 63, 1-20. doi: 10.1186/s12974-024-03048-0 |
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2024 Journal Article Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosisTu, Cui, Buckle, Irina, Leal Rojas, Ingrid, Rossi, Gustavo Rodrigues, Sester, David P, Moore, Andrew S, Radford, Kristen, Guillerey, Camille and Souza‐Fonseca‐Guimaraes, Fernando (2024). Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis. Clinical & Translational Immunology, 13 (3) e1501, e1501. doi: 10.1002/cti2.1501 |
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2023 Journal Article Characterization of human engraftment and hemophagocytic lymphohistiocytosis in NSG-SGM3 neonate mice engrafted with purified CD34+ hematopoietic stem cellsLiam, O'Brien, Carina, Walpole, Ingrid, Leal-Rojas, Svetlana, Shatunova, Andrew, Moore, Winkler, Ingrid G, Camille, Guillerey and Radford, Kristen J (2023). Characterization of human engraftment and hemophagocytic lymphohistiocytosis in NSG-SGM3 neonate mice engrafted with purified CD34+ hematopoietic stem cells. Experimental Hematology, 130 104134, 104134. doi: 10.1016/j.exphem.2023.11.008 |
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2023 Journal Article Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetesLeung, Sherman S., Lenchik, Nataliya, Mathews, Clayton, Pugliese, Alberto, McCarthy, Domenica A., Le Bagge, Selena, Ewing, Adam, Harris, Mark, Radford, Kristen J., Borg, Danielle J., Gerling, Ivan and Forbes, Josephine M. (2023). Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Scientific Reports, 13 (1) 12948, 1-15. doi: 10.1038/s41598-023-39243-x |
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2023 Journal Article High dimensional analysis reveals distinct NK cell subsets but conserved response to stimulation in umbilical cord blood and adult peripheral bloodBuckle, Irina, Johnson, Anthony, Rojas, Ingrid Leal, Weinert, Vicky, Sester, David P., Radford, Kristen and Guillerey, Camille (2023). High dimensional analysis reveals distinct NK cell subsets but conserved response to stimulation in umbilical cord blood and adult peripheral blood. European Journal of Immunology, 53 (6) 2250118, 1-13. doi: 10.1002/eji.202250118 |
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2023 Journal Article CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunityGressier, Elise, Schulte-Schrepping, Jonas, Petrov, Lev, Brumhard, Sophia, Stubbemann, Paula, Hiller, Anna, Obermayer, Benedikt, Spitzer, Jasper, Kostevc, Tomislav, Whitney, Paul G., Bachem, Annabell, Odainic, Alexandru, van de Sandt, Carolien, Nguyen, Thi H. O., Ashhurst, Thomas, Wilson, Kayla, Oates, Clare V. L., Gearing, Linden. J., Meischel, Tina, Hochheiser, Katharina, Greyer, Marie, Clarke, Michele, Kreutzenbeck, Maike, Gabriel, Sarah S., Kastenmüller, Wolfgang, Kurts, Christian, Londrigan, Sarah L., Kallies, Axel, Kedzierska, Katherine ... Bedoui, Sammy (2023). CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity. Nature Immunology, 24 (6), 979-990. doi: 10.1038/s41590-023-01517-x |
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2023 Journal Article Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infectionSikder, Md. Al Amin, Rashid, Ridwan B., Ahmed, Tufael, Sebina, Ismail, Howard, Daniel R., Ullah, Md. Ashik, Rahman, Muhammed Mahfuzur, Lynch, Jason P., Curren, Bodie, Werder, Rhiannon B., Simpson, Jennifer, Bissell, Alec, Morrison, Mark, Walpole, Carina, Radford, Kristen J., Kumar, Vinod, Woodruff, Trent M., Ying, Tan Hui, Ali, Ayesha, Kaiko, Gerard E., Upham, John W., Hoelzle, Robert D., Cuív, Páraic Ó., Holt, Patrick G., Dennis, Paul G. and Phipps, Simon (2023). Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection. Immunity, 56 (5), 1098-1114.e10. doi: 10.1016/j.immuni.2023.03.002 |
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2022 Journal Article The Human Dendritic Cell Atlas: An Integrated Transcriptional Tool to Study Human Dendritic Cell BiologyElahi, Zahra, Angel, Paul W., Butcher, Suzanne K., Rajab, Nadia, Choi, Jarny, Deng, Yidi, Mintern, Justine D., Radford, Kristen and Wells, Christine A. (2022). The Human Dendritic Cell Atlas: An Integrated Transcriptional Tool to Study Human Dendritic Cell Biology. Journal of Immunology, 209 (12), 2352-2361. doi: 10.4049/jimmunol.2200366 |
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2022 Journal Article The Human Dendritic Cell Atlas: an integrated transcriptional tool to study human dendritic cell biologyElahi, Zahra, Angel, Paul W., Butcher, Suzanne K., Rajab, Nadia, Choi, Jarny, Deng, Yidi, Mintern, Justine D., Radford, Kristen and Wells, Christine A. (2022). The Human Dendritic Cell Atlas: an integrated transcriptional tool to study human dendritic cell biology. Journal of Immunology, 209 (12), 2352-2361. doi: 10.4049/jimmunol.2200366 |
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2022 Journal Article Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T CellsLeung, Sherman S., Borg, Danielle J., McCarthy, Domenica A., Boursalian, Tamar E., Cracraft, Justen, Zhuang, Aowen, Fotheringham, Amelia K., Flemming, Nicole, Watkins, Thomas, Miles, John J., Groop, Per-Henrik, Scheijen, Jean L., Schalkwijk, Casper G., Steptoe, Raymond J., Radford, Kristen J., Knip, Mikael and Forbes, Josephine M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71 (9), 1994-2008. doi: 10.2337/db22-0177 |
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2022 Journal Article Discordance in STING-induced activation and cell death between mouse and human dendritic cell populationsPang, Ee Shan, Daraj, Ghazal, Balka, Katherine R., De Nardo, Dominic, Macri, Christophe, Hochrein, Hubertus, Masterman, Kelly-Anne, Tan, Peck S., Shoppee, Angus, Magill, Zoe, Jahan, Nazneen, Bafit, Mariam, Zhan, Yifan, Kile, Benjamin T., Lawlor, Kate E., Radford, Kristen J., Wright, Mark D. and O'Keeffe, Meredith (2022). Discordance in STING-induced activation and cell death between mouse and human dendritic cell populations. Frontiers in Immunology, 13 794776. doi: 10.3389/fimmu.2022.794776 |
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2022 Journal Article DROSHA but not DICER is required for human haematopoietic stem cell functionGu, Karen, Walpole, Carina, Gooneratne, Shayarana, Liu, Xin, Haigh, Oscar L., Radford, Kristen J. and Chong, Mark M. W. (2022). DROSHA but not DICER is required for human haematopoietic stem cell function. Clinical and Translational Immunology, 11 (1) e1361, e1361. doi: 10.1002/cti2.1361 |
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2021 Journal Article Conventional Type 1 dendritic cells (cDC1) as cancer therapeutics: challenges and opportunitiesJohnson, Phillip, Rosendahl, Nikita and Radford, Kristen J. (2021). Conventional Type 1 dendritic cells (cDC1) as cancer therapeutics: challenges and opportunities. Expert Opinion on Biological Therapy, 22 (4), 1-8. doi: 10.1080/14712598.2022.1994943 |
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2021 Journal Article Cytokines as a marker of central nervous system autoantibody associated epilepsyGillinder, Lisa, McCombe, Pamela, Powell, Tamara, Hartel, Gunter, Gillis, David, Rojas, Ingrid Leal and Radford, Kristen (2021). Cytokines as a marker of central nervous system autoantibody associated epilepsy. Epilepsy Research, 176 106708, 1-7. doi: 10.1016/j.eplepsyres.2021.106708 |
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2021 Journal Article Elucidating the motif for CpG oligonucleotide binding to the dendritic cell receptor DEC-205 leads to improved adjuvants for liver-resident memoryLi, Jessica, Panetta, Fatma, O’Keeffe, Meredith, Leal Rojas, Ingrid M., Radford, Kristen J., Zhang, Jian-Guo, Fernandez-Ruiz, Daniel, Davey, Gayle M., Gully, Benjamin S., Tullett, Kirsteen M., Rossjohn, Jamie, Berry, Richard, Lee, Chin-Nien, Lahoud, Mireille H., Heath, William R. and Caminschi, Irina (2021). Elucidating the motif for CpG oligonucleotide binding to the dendritic cell receptor DEC-205 leads to improved adjuvants for liver-resident memory. The Journal of Immunology, 207 (7), 1836-1847. doi: 10.4049/jimmunol.2001153 |
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2021 Journal Article T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetesForbes, Josephine M., McCarthy, Domenica A., Kassianos, Andrew J., Baskerville, Tracey, Fotheringham, Amelia J., Giuliani, Kurt T. K., Grivei, Anca, Murphy, Andrew J., Flynn, Michelle C., Sullivan, Mitchell A., Chandrashekar, Preeti, Whiddett, Rani, Radford, Kristen J., Flemming, Nicole, Beard, Sam S., D’Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasdale, Stephanie, Russell, Anthony, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Healy, Helen, Harris, Mark, Donaghue, Kim, Johnson, David W., Cotterill, Andrew, Barrett, Helen L. and O’Moore-Sullivan, Trisha (2021). T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes. Diabetes, 70 (8), 1754-1766. doi: 10.2337/db20-1081 |
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2021 Conference Publication Activation of stimulator of interferon genes in dendritic cells induces interferon-lambda and subset- and species-specific dendritic cell deathPang, Ee Shan, Daraj, Ghazal, Macri, Christophe, Balka, Katherine, de Nardo, Dominic, Hochrein, Hubertus, Masterman, Kelly-Anne, Zhan, Yifan, Kile, Benjamin, Lawlor, Kate, Radford, Kristen, Wright, Mark and O’Keeffe, Meredith (2021). Activation of stimulator of interferon genes in dendritic cells induces interferon-lambda and subset- and species-specific dendritic cell death. Immunology 2021™ Meeting, Online, 10–15 May 2021. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.206.supp.111.28 |
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2021 Journal Article Adhesion to E-selectin primes macrophages for activation through AKT and mTORDavies, Julie M., Radford, Kristen J., Begun, Jakob, Levesque, Jean-Pierre and Winkler, Ingrid G. (2021). Adhesion to E-selectin primes macrophages for activation through AKT and mTOR. Immunology and Cell Biology, 99 (6) imcb.12447, 622-639. doi: 10.1111/imcb.12447 |
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2021 Journal Article Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse modelLee, Yoke Seng, O'Brien, Liam J., Walpole, Carina M., Pearson, Frances E., Leal-Rojas, Ingrid M., Masterman, Kelly-Anne, Atkinson, Victoria, Barbour, Andrew and Radford, Kristen J. (2021). Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model. Journal for ImmunoTherapy of Cancer, 9 (3) e001963, 1-12. doi: 10.1136/jitc-2020-001963 |
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2021 Journal Article Enhancing the immunogenicity of cancer vaccines by harnessing CLEC9ALahoud, M. H. and Radford, K. J. (2021). Enhancing the immunogenicity of cancer vaccines by harnessing CLEC9A. Human Vaccines and Immunotherapeutics, 18 (1) 1873056, 1-5. doi: 10.1080/21645515.2021.1873056 |
