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2021 Journal Article Investigation of receptor heteromers using NanoBRET ligand bindingJohnstone, Elizabeth K. M., See, Heng B., Abhayawardana, Rekhati S., Song, Angela, Rosengren, K. Johan, Hill, Stephen J. and Pfleger, Kevin D. G. (2021). Investigation of receptor heteromers using NanoBRET ligand binding. International Journal of Molecular Sciences, 22 (3) 1082, 1-16. doi: 10.3390/ijms22031082 |
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2021 Journal Article Site-specific modification and segmental isotope labelling of HMGN1 reveals long-range conformational perturbations caused by posttranslational modificationsNiederacher, Gerhard, Urwin, Debra, Dijkwel, Yasmin, Tremethick, David J., Rosengren, K. Johan, Becker, Christian F. W. and Conibear, Anne C. (2021). Site-specific modification and segmental isotope labelling of HMGN1 reveals long-range conformational perturbations caused by posttranslational modifications. RSC Chemical Biology, 2 (2), 537-550. doi: 10.1039/d0cb00175a |
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2021 Journal Article Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor bindingHo, Thao N. T., Lee, Han Siean, Swaminathan, Shilpa, Goodwin, Lewis, Rai, Nishant, Ushay, Brianna, Lewis, Richard J., Rosengren, K. Johan and Conibear, Anne C. (2021). Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. RSC Medicinal Chemistry, 12 (9), 1574-1584. doi: 10.1039/d1md00182e |
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2020 Journal Article Insights into the interaction of LVV-hemorphin-7 with angiotensin II type 1 receptorAli, Amanat, Johnstone, Elizabeth K. M., Baby, Bincy, See, Heng B., Song, Angela, Rosengren, K. Johan, Pfleger, Kevin D. G., Ayoub, Mohammed Akli and Vijayan, Ranjit (2020). Insights into the interaction of LVV-hemorphin-7 with angiotensin II type 1 receptor. International Journal of Molecular Sciences, 22 (1) 209, 209-14. doi: 10.3390/ijms22010209 |
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2020 Journal Article Recifin A, initial example of the Tyr-lock peptide structural family, is a selective allosteric inhibitor of Tyrosyl-DNA phosphodiesterase IKrumpe, Lauren R. H., Wilson, Brice A. P., Marchand, Christophe, Sunassee, Suthananda N., Bermingham, Alun, Wang, Wenjie, Price, Edmund, Guszczynski, Tad, Kelley, James A., Gustafson, Kirk R., Pommier, Yves, Rosengren, K. Johan, Schroeder, Christina I. and O'Keefe, Barry R. (2020). Recifin A, initial example of the Tyr-lock peptide structural family, is a selective allosteric inhibitor of Tyrosyl-DNA phosphodiesterase I. Journal of the American Chemical Society, 142 (50), 21178-21188. doi: 10.1021/jacs.0c10418 |
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2020 Journal Article Defining the familial fold of the vicilin-buried peptide familyPayne, Colton D., Vadlamani, Grishma, Fisher, Mark F., Zhang, Jingjing, Clark, Richard J., Mylne, Joshua S. and Rosengren, K. Johan (2020). Defining the familial fold of the vicilin-buried peptide family. Journal of Natural Products, 83 (10), 3030-3040. doi: 10.1021/acs.jnatprod.0c00594 |
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2020 Journal Article Effects of C-Terminal B-Chain Modifications in a Relaxin 3 Agonist AnaloguePraveen, Praveen, Tailhades, Julien, Rosengren, K. Johan, Liu, Mengjie, Wade, John D., Bathgate, Ross A. D. and Hossain, Mohammed Akhter (2020). Effects of C-Terminal B-Chain Modifications in a Relaxin 3 Agonist Analogue. ACS Medicinal Chemistry Letters, 11 (11) acsmedchemlett.0c00456, 2336-2340. doi: 10.1021/acsmedchemlett.0c00456 |
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2020 Journal Article The genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitidesFisher, Mark F., Payne, Colton D., Chetty, Thaveshini, Crayn, Darren M., Berkowitz, Oliver, Whelan, James, Rosengren, K. Johan and Mylne, Joshua S. (2020). The genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides. Journal of Biological Chemistry, 295 (42), 14510-14521. doi: 10.1074/jbc.ra120.014781 |
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2020 Journal Article Exploring the use of helicogenic amino acids for optimising single chain relaxin-3 peptide agonistsLee, Han Siean, Wang, Shu Hui, Daniel, James T., Hossain, Mohammed Akhter, Clark, Richard J., Bathgate, Ross A. D. and Rosengren, K. Johan (2020). Exploring the use of helicogenic amino acids for optimising single chain relaxin-3 peptide agonists. Biomedicines, 8 (10) 415, 1-16. doi: 10.3390/biomedicines8100415 |
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2020 Journal Article Backbone cyclization and dimerization of LL-37-derived peptides enhance antimicrobial activity and proteolytic stabilityGunasekera, Sunithi, Muhammad, Taj, Strömstedt, Adam A., Rosengren, K. Johan and Göransson, Ulf (2020). Backbone cyclization and dimerization of LL-37-derived peptides enhance antimicrobial activity and proteolytic stability. Frontiers in Microbiology, 11 168, 168. doi: 10.3389/fmicb.2020.00168 |
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2020 Journal Article Development of relaxin-3 agonists and antagonists based on grafted disulfide-stabilized scaffoldsLee, Han Siean, Postan, Michael, Song, Angela, Clark, Richard J., Bathgate, Ross A. D., Haugaard-Kedström, Linda M. and Rosengren, K. Johan (2020). Development of relaxin-3 agonists and antagonists based on grafted disulfide-stabilized scaffolds. Frontiers in Chemistry, 8 87, 87. doi: 10.3389/fchem.2020.00087 |
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2019 Journal Article The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensinsBleackley, Mark R., Dawson, Charlotte S., Payne, Jennifer A.E., Harvey, Peta J., Rosengren, K. Johan, Quimbar, Pedro, Garcia-Ceron, Donovan, Lowe, Rohan, Bulone, Vincent, van der Weerden, Nicole L, Craik, David J. and Anderson, Marilyn A. (2019). The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins. The Cell Surface, 5 100026, 100026. doi: 10.1016/j.tcsw.2019.100026 |
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2019 Journal Article An orbitide from Ratibida columnifera seed containing 16 amino acid residuesFisher, Mark F., Payne, Colton D., Rosengren, K. Johan and Mylne, Joshua S. (2019). An orbitide from Ratibida columnifera seed containing 16 amino acid residues. Journal of Natural Products, 82 (8) acs.jnatprod.9b00111, 2152-2158. doi: 10.1021/acs.jnatprod.9b00111 |
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2019 Journal Article Random coil shifts of posttranslationally modified amino acidsConibear, Anne C., Rosengren, K. Johan, Becker, Christian F. W. and Kaehlig, Hanspeter (2019). Random coil shifts of posttranslationally modified amino acids. Journal of Biomolecular NMR, 73 (10-11), 587-599. doi: 10.1007/s10858-019-00270-4 |
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2019 Journal Article An ancient peptide family buried within vicilin precursorsZhang, Jingjing, Payne, Colton D., Pouvreau, Benjamin, Schaefer, Hanno, Fisher, Mark F., Taylor, Nicolas L., Berkowitz, Oliver, Whelan, James, Rosengren, K. Johan and Mylne, Joshua S. (2019). An ancient peptide family buried within vicilin precursors. ACS Chemical Biology, 14 (5) acschembio.9b00167, 979-993. doi: 10.1021/acschembio.9b00167 |
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2018 Journal Article Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphateMinchin, Rodney F., Rosengren, K. Johan, Burow, Rachel and Butcher, Neville J. (2018). Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate. Biochemical Pharmacology, 158, 153-160. doi: 10.1016/j.bcp.2018.10.013 |
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2018 Journal Article Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptidesSousa, Silmara R., McArthur, Jeffrey R., Brust, Andreas, Bhola, Rebecca F., Rosengren, K. Johan, Ragnarsson, Lotten, Dutertre, Sebastien, Alewood, Paul F., Christie, Macdonald J., Adams, David J., Vetter, Irina and Lewis, Richard J. (2018). Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Scientific Reports, 8 (1) 13397, 13397. doi: 10.1038/s41598-018-31245-4 |
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2018 Journal Article Binding conformation and determinants of a single chain peptide antagonist at the relaxin-3 receptor RXFP3Haugaard-Kedström, Linda M., Lee, Han Siean, Jones, Maryon V., Song, Angela, Rathod, Vishaal, Hossain, Mohammed Akhter, Bathgate, Ross A.D. and Rosengren, K. Johan (2018). Binding conformation and determinants of a single chain peptide antagonist at the relaxin-3 receptor RXFP3. Journal of Biological Chemistry, 293 (41), 15765-15776. doi: 10.1074/jbc.ra118.002611 |
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2018 Journal Article Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptorWong, Lilian L. L., Scott, Daniel James, Hossain, Mohammed Akhter, Kaas, Quentin, Rosengren, K. Johan and Bathgate, Ross A. D. (2018). Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor. Journal of Biological Chemistry, 293 (41), 15777-15789. doi: 10.1074/jbc.ra118.002645 |
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2018 Journal Article Prediction of disulfide dihedral angles using chemical shiftsArmstrong, David A., Kaas, Quentin and Rosengren, K. Johan (2018). Prediction of disulfide dihedral angles using chemical shifts. Chemical Science, 9 (31), 6548-6556. doi: 10.1039/c8sc01423j |
