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2024 Journal Article Novel scorpion toxin ω-Buthitoxin-Hf1a selectively inhibits calcium influx via CaV3.3 and CaV3.2 and alleviates allodynia in a mouse model of acute postsurgical painWang, Dan, Herzig, Volker, Dekan, Zoltan, Rosengren, K. Johan, Payne, Colton D., Hasan, Md. Mahadhi, Zhuang, Jiajie, Bourinet, Emmanuel, Ragnarsson, Lotten, Alewood, Paul F. and Lewis, Richard J. (2024). Novel scorpion toxin ω-Buthitoxin-Hf1a selectively inhibits calcium influx via CaV3.3 and CaV3.2 and alleviates allodynia in a mouse model of acute postsurgical pain. International Journal of Molecular Sciences, 25 (9) 4745. doi: 10.3390/ijms25094745 |
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2024 Journal Article The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisationBudusan, Elena, Payne, Colton D., Gonzalez, Tye I., Obergrussberger, Alison, Becker, Nadine, Clark, Richard J., Rosengren, K. Johan, Rash, Lachlan D. and Cristofori-Armstrong, Ben (2024). The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation. Biochemical Pharmacology, 228 116175, 116175. doi: 10.1016/j.bcp.2024.116175 |
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2024 Journal Article Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analoguesSmallwood, Taylor B., Krumpe, Lauren R. H., Payne, Colton D., Klein, Victoria G., O'Keefe, Barry R., Clark, Richard J., Schroeder, Christina I. and Rosengren, K. Johan (2024). Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analogues. Chemical Science, 15 (33), 13227-13233. doi: 10.1039/d4sc01976h |
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2023 Journal Article Side‐chain dynamics of the α<sub>1B</sub>‐adrenergic receptor determined by NMR via methyl relaxationBaumann, Christian, Chiang, Wan‐Chin, Valsecchi, Renato, Jurt, Simon, Deluigi, Mattia, Schuster, Matthias, Rosengren, Karl Johan, Plückthun, Andreas and Zerbe, Oliver (2023). Side‐chain dynamics of the α1B‐adrenergic receptor determined by NMR via methyl relaxation. Protein Science, 32 (11) e4801, 1-18. doi: 10.1002/pro.4801 |
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2023 Journal Article Noncovalent peptide stapling using alpha-methyl-l-phenylalanine for α-helical peptidomimeticsBathgate, Ross A. D., Praveen, Praveen, Sethi, Ashish, Furuya, Werner I., Dhingra, Rishi R., Kocan, Martina, Ou, Qinghao, Valkovic, Adam L., Gil-Miravet, Isis, Navarro-Sánchez, Mónica, Olucha-Bordonau, Francisco E., Gundlach, Andrew L., Rosengren, K. Johan, Gooley, Paul R., Dutschmann, Mathias and Hossain, Mohammed Akhter (2023). Noncovalent peptide stapling using alpha-methyl-l-phenylalanine for α-helical peptidomimetics. Journal of the American Chemical Society, 145 (37), 20242-20247. doi: 10.1021/jacs.3c02743 |
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2023 Journal Article Stretching peptides to generate small molecule β-strand mimicsAdams, Zoë C., Silvestri, Anthony P., Chiorean, Sorina, Flood, Dillon T., Balo, Brian P., Shi, Yifan, Holcomb, Matthew, Walsh, Shawn I., Maillie, Colleen A., Pierens, Gregory K., Forli, Stefano, Rosengren, K. Johan and Dawson, Philip E. (2023). Stretching peptides to generate small molecule β-strand mimics. ACS Central Science, 9 (4), 648-656. doi: 10.1021/acscentsci.2c01462 |
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2023 Journal Article Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMRKuschert, Sarah, Stroet, Martin, Chin, Yanni Ka-Yan, Conibear, Anne Claire, Jia, Xinying, Lee, Thomas, Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Güntert, Peter, Rosengren, Karl Johan, Mark, Alan Edward and Mobli, Mehdi (2023). Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMR. Magnetic Resonance, 4 (1), 57-72. doi: 10.5194/mr-4-57-2023 |
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2022 Journal Article Engineering peptide inhibitors of the HFE–transferrin receptor 1 complexGoncalves Monteiro, Daniela Goncalves, Rishi, Gautam, Gorman, Declan M., Burnet, Guillaume, Aliyanto, Randy, Rosengren, K. Johan, Frazer, David M., Subramaniam, V. Nathan and Clark, Richard J. (2022). Engineering peptide inhibitors of the HFE–transferrin receptor 1 complex. Molecules, 27 (19) 6581, 1-13. doi: 10.3390/molecules27196581 |
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2022 Journal Article Secondary structure transitions for a family of amyloidogenic, antimicrobial uperin 3 peptides in contact with sodium dodecyl sulfatePrasad, Anup K., Tiwari, Chandni, Ray, Sourav, Holden, Stephanie, Armstrong, David A., Rosengren, K. Johan, Rodger, Alison, Panwar, Ajay S. and Martin, Lisandra L. (2022). Secondary structure transitions for a family of amyloidogenic, antimicrobial uperin 3 peptides in contact with sodium dodecyl sulfate. ChemPlusChem, 87 (1) e202100408, e202100408. doi: 10.1002/cplu.202100408 |
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2021 Journal Article Barrettides: a peptide family specifically produced by the deep-sea sponge Geodia barrettiSteffen, Karin, Laborde, Quentin, Gunasekera, Sunithi, Payne, Colton D., Rosengren, K. Johan, Riesgo, Ana, Göransson, Ulf and Cárdenas, Paco (2021). Barrettides: a peptide family specifically produced by the deep-sea sponge Geodia barretti. Journal of Natural Products, 84 (12) acs.jnatprod.1c00938, 3138-3146. doi: 10.1021/acs.jnatprod.1c00938 |
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2021 Journal Article Heimdallarchaea encodes profilin with eukaryotic-like actin regulation and polyproline bindingSurvery, Sabeen, Hurtig, Fredrik, Haq, Syed Razaul, Eriksson, Jens, Guy, Lionel, Rosengren, K. Johan, Lindås, Ann-Christin and Chi, Celestine N. (2021). Heimdallarchaea encodes profilin with eukaryotic-like actin regulation and polyproline binding. Communications Biology, 4 (1) 1024, 1-14. doi: 10.1038/s42003-021-02543-x |
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2021 Journal Article Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptidesPayne, Colton D., Vadlamani, Grishma, Hajiaghaalipour, Fatemeh, Muhammad, Taj, Fisher, Mark F., Andersson, Håkan S., Göransson, Ulf, Clark, Richard J., Bond, Charles S., Mylne, Joshua S. and Rosengren, K. Johan (2021). Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides. RSC Chemical Biology, 2 (6), 1682-1691. doi: 10.1039/d1cb00155h |
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2021 Journal Article A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4Clark, Richard J., Phan, Thanh Huyen, Song, Angela, Ouellette, André J., Conibear, Anne C. and Rosengren, K. Johan (2021). A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4. Peptide Science, 114 (1) e24250. doi: 10.1002/pep2.24250 |
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2021 Journal Article Development of synthetic human and mouse C5a: application to binding and functional assays in vitro and in vivoGorman, Declan M., Li, Xaria X., Payne, Colton D., Cui, Cedric S., Lee, John D., Rosengren, K. Johan, Woodruff, Trent M. and Clark, Richard J. (2021). Development of synthetic human and mouse C5a: application to binding and functional assays in vitro and in vivo. ACS Pharmacology and Translational Science, 4 (6) acsptsci.1c00199, 1808-1817. doi: 10.1021/acsptsci.1c00199 |
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2021 Journal Article Structural characterization of the PawL-derived peptide family, an ancient subfamily of orbitidesPayne, Colton D., Fisher, Mark F., Mylne, Joshua S. and Rosengren, K. Johan (2021). Structural characterization of the PawL-derived peptide family, an ancient subfamily of orbitides. Journal of Natural Products, 84 (11) acs.jnatprod.1c00672, 2914-2922. doi: 10.1021/acs.jnatprod.1c00672 |
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2021 Journal Article Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivoSmallwood, Taylor B., Navarro, Severine, Cristofori-Armstrong, Ben, Watkins, Thomas S., Tungatt, Katie, Ryan, Rachael Y.M., Haigh, Oscar L., Lutzky, Viviana P., Mulvenna, Jason P., Rosengren, K. Johan, Loukas, Alex, Miles, John J. and Clark, Richard J. (2021). Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo. Journal of Biological Chemistry, 297 (1) 100834, 1-14. doi: 10.1016/j.jbc.2021.100834 |
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2021 Journal Article A chameleonic macrocyclic peptide with drug delivery applicationsPayne, Colton D., Franke, Bastian, Fisher, Mark F., Hajiaghaalipour, Fatemeh, McAleese, Courtney E., Song, Angela, Eliasson, Carl, Zhang, Jingjing, Jayasena, Achala S., Vadlamani, Grishma, Clark, Richard J., Minchin, Rodney F., Mylne, Joshua S. and Rosengren, K. Johan (2021). A chameleonic macrocyclic peptide with drug delivery applications. Chemical Science, 12 (19), 6670-6683. doi: 10.1039/d1sc00692d |
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2021 Conference Publication Structure-function of the spider peptide ProTx-IIIZhao, Tianjiao, Rosengren, Johan K., Cardoso, Fernanda C. and Lewis, Richard J. (2021). Structure-function of the spider peptide ProTx-III. Venom to Drugs, Daydream Island, QLD Australia, 15-19 March 2021. |
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2021 Journal Article Pursuing orally bioavailable hepcidin analogues via cyclic N-methylated mini-hepcidinsGoncalves Monteiro, Daniela, van Dijk, Johannes W. A., Aliyanto, Randy, Fung, Eileen, Nemeth, Elizabeta, Ganz, Tomas, Rosengren, Johan and Clark, Richard J. (2021). Pursuing orally bioavailable hepcidin analogues via cyclic N-methylated mini-hepcidins. Biomedicines, 9 (2) 164, 1-14. doi: 10.3390/biomedicines9020164 |
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2021 Journal Article Chemical synthesis and NMR solution structure of conotoxin GXIA from Conus geographusArmstrong, David A., Jin, Ai-Hua, Braga Emidio, Nayara, Lewis, Richard J., Alewood, Paul F. and Rosengren, K. Johan (2021). Chemical synthesis and NMR solution structure of conotoxin GXIA from Conus geographus. Marine Drugs, 19 (2) 60, 1-14. doi: 10.3390/md19020060 |
