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2016 Journal Article Engineering of a novel simplified human insulin-Like peptide 5 agonistPatil, Nitin A., Hughes, Richard A., Rosengren, K. Johan, Kocan, Martina, Ang, Sheng Yu, Tailhades, Julien, Separovic, Frances, Summers, Roger J., Grosse, Johannes, Wade, John D., Bathgate, Ross A. D. and Hossain, Mohammed Akhter (2016). Engineering of a novel simplified human insulin-Like peptide 5 agonist. Journal of Medicinal Chemistry, 59 (5), 2118-2125. doi: 10.1021/acs.jmedchem.5b01786 |
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2016 Journal Article A tripartite approach identifies the major sunflower seed albuminsJayasena, Achala S., Franke, Bastian, Rosengren, Johan and Mylne,Joshua S. (2016). A tripartite approach identifies the major sunflower seed albumins. Theoretical and Applied Genetics, 129 (3), 613-629. doi: 10.1007/s00122-015-2653-3 |
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2016 Journal Article Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclizationConibear, Anne C., Chaousis, Stephanie, Durek, Thomas, Rosengren, K. Johan, Craik, David J. and Schroeder, Christina I. (2016). Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization. Biopolymers, 106 (1), 89-100. doi: 10.1002/bip.22767 |
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2016 Conference Publication Development of peptide therapeutics for iron disordersGoncalves, Daniela, Rishi, Gautam, Aliyanto, Randy, Rosengren, Johan, Subramaniam, Nathan, Frazer, David and Clark, Richard (2016). Development of peptide therapeutics for iron disorders. 6th Meeting of the International BioIron Society, Zhejiang University, Hangzhou, China, 8-10 September 2015. Hoboken, NJ, United States: John Wiley & Sons. |
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2016 Conference Publication Design, synthesis and biological activity of hydrocarbon stapled single-chain relaxin-3 analogueHojo, K., Hossain, M. A., Rosengren, K. J., Ma, S., Gundlach, A. L., Tsuda, Y., Hidaka, K., Bathgate, R. A. and Wade, J. D. (2016). Design, synthesis and biological activity of hydrocarbon stapled single-chain relaxin-3 analogue. 34th European Peptide Symposium and 8th International Peptide Symposium, Leipzig, Germany, 4-9 September 2016. Oxford, United Kingdom: John Wiley & Sons. |
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2016 Journal Article Natural structural diversity within a conserved cyclic peptide scaffoldElliott, Alysha G., Franke, Bastian, Armstrong, David A., Craik, David J., Mylne, Joshua S. and Rosengren, K. Johan (2016). Natural structural diversity within a conserved cyclic peptide scaffold. Amino Acids, 49 (1), 1-14. doi: 10.1007/s00726-016-2333-x |
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2016 Conference Publication Structural Features of An Unusual Sun-Flower Proalbumin Protein That Gives Rise to a Small Cyclic Peptide and a Seed Storage ProteinFranke, B., James, A., Mobli, M., Mylne, J. S. and Rosengren, K. J. (2016). Structural Features of An Unusual Sun-Flower Proalbumin Protein That Gives Rise to a Small Cyclic Peptide and a Seed Storage Protein. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. HOBOKEN: Wiley. |
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2015 Journal Article Distribution of circular proteins in plants: large-scale mapping of cyclotides in the ViolaceaeBurman, Robert, Yeshak, Mariamawit Y., Larsson, Sonny, Craik, David J., Rosengren, K. Johan and Goeransson, Ulf (2015). Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae. Frontiers in Plant Science, 6 (855) 855, 1-13. doi: 10.3389/fpls.2015.00855 |
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2015 Journal Article Central relaxin-3 receptor (RXFP3) activation reduces elevated, but not basal, anxiety-like behaviour in C57BL/6J miceZhang, Carry, Chua, Berenice E., Yang, Annie, Shabanpoor, Fazel, Hossain, Mohammad Akhter, Wade, John D., Rosengren, K. Johan, Smith, Craig M. and Gundlach A.L. (2015). Central relaxin-3 receptor (RXFP3) activation reduces elevated, but not basal, anxiety-like behaviour in C57BL/6J mice. Behavioural Brain Research, 292, 125-132. doi: 10.1016/j.bbr.2015.06.010 |
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2015 Journal Article Chemically synthesized dicarba H2 relaxin analogues retain strong RXFP1 receptor activity but show an unexpected loss of in vitro serum stabilityHossain, Mohammed Akhter, Haugaard-Kedstrom, Linda M., Rosengren, K. Johan, Bathgate, Ross A. D. and Wade, John D. (2015). Chemically synthesized dicarba H2 relaxin analogues retain strong RXFP1 receptor activity but show an unexpected loss of in vitro serum stability. Organic and Biomolecular Chemistry, 13 (44), 10895-10903. doi: 10.1039/c5ob01539a |
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2015 Journal Article Isolation, characterization, and synthesis of the barrettides: disulfide-containing peptides from the marine sponge Geodia barrettiCarstens, Bodil B., Rosengren, K. Johan, Gunasekera, Sunithi, Schempp, Stefanie, Bohlin, Lars, Dahlstrom, Mia, Clark, Richard J. and Goransson, Ulf (2015). Isolation, characterization, and synthesis of the barrettides: disulfide-containing peptides from the marine sponge Geodia barretti. Journal of Natural Products, 78 (8), 1886-1893. doi: 10.1021/acs.jnatprod.5b00210 |
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2015 Journal Article Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faeciumHimeno, Kohei, Rosengren, K. Johan, Inoue, Tomoko, Perez, Rodney H., Colgrave, Michelle L., Lee, Han Siean, Chan, Lai Y., Henriques, Sonia Troeira, Fujita, Koji, Ishibashi, Naoki, Zendo, Takeshi, Wilaipun, Pongtep, Nakayama, Jiro, Leelawatcharamas, Vichien, Jikuya, Hiroyuki, Craik, David J. and Sonomoto, Kenji (2015). Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium. Biochemistry, 54 (31), 4863-4876. doi: 10.1021/acs.biochem.5b00196 |
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2015 Journal Article Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriensCardoso, Fernanda C., Deka, Zoltan, Rosengren, K. Johan, Erickson, Andelain, Vetter, Irina, Deuis, Jennifer R., Herzig, Volker, Alewood, Paul F., King, Glenn F. and Lewis, Richard J. (2015). Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens. Molecular Pharmacology, 88 (2), 291-303. doi: 10.1124/mol.115.098178 |
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2015 Journal Article Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibitionde Veer, Simon J., Swedberg, Joakim E., Akcan, Muharrem, Rosengren, K. Johan, Brattsand, Maria, Craik, David J. and Harris, Jonathan M. (2015). Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition. Biochemical Journal, 469 (2), 243-253. doi: 10.1042/BJ20150412 |
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2015 Journal Article Synthesis and pharmacological characterization of a europium-labelled single-chain antagonist for binding studies of the relaxin-3 receptor RXFP3Haugaard-Kedstrom, Linda M, Wong, Lillian L. L, Bathgate, Ross A. D and Rosengren, K. Johan (2015). Synthesis and pharmacological characterization of a europium-labelled single-chain antagonist for binding studies of the relaxin-3 receptor RXFP3. Amino Acids, 47 (6) 1961, 1267-1271. doi: 10.1007/s00726-015-1961-x |
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2015 Journal Article A cactus-derived toxin-like cystine knot peptide with selective antimicrobial activityAboye, Teshome L, Stromstedt, Adam A, Gunasekera, Sunithi, Bruhn, Jan G, El-Seedi, Hesham, Rosengren K.J. and Goransson, Ulf (2015). A cactus-derived toxin-like cystine knot peptide with selective antimicrobial activity. ChemBioChem, 16 (7), 1068-1077. doi: 10.1002/cbic.201402704 |
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2015 Journal Article Solution structure, aggregation behavior, and flexibility of human relaxin-2Haugaard-Kedstrom, Linda, Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Rinderknecht, Ernst, Wade, John D., Craik, David J. and Rosengren, Karl Johan (2015). Solution structure, aggregation behavior, and flexibility of human relaxin-2. ACS Chemical Biology, 10 (3), 891-900. doi: 10.1021/cb500918v |
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2015 Journal Article Stabilization of the Cysteine-Rich Conotoxin MrIA by Using a 1,2,3-Triazole as a Disulfide Bond MimeticGori, Alessandro, Wang, Ching-I A., Harvey, Peta J., Rosengren, K. Johan, Bhola, Rebecca F., Gelmi, Maria L., Longhi, Renato, Christie, Macdonald J., Lewis, Richard J., Alewood, Paul F. and Brust, Andreas (2015). Stabilization of the Cysteine-Rich Conotoxin MrIA by Using a 1,2,3-Triazole as a Disulfide Bond Mimetic. Angewandte Chemie - International Edition, 54 (4), 1361-1364. doi: 10.1002/anie.201409678 |
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2015 Book Chapter Structural studies of cyclotidesDaly, Norelle L. and Rosengren, K. Johan (2015). Structural studies of cyclotides. Plant cyclotides. (pp. 155-186) edited by David Craik. Cambridge, MA, United States: Academic Press. doi: 10.1016/bs.abr.2015.09.003 |
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2014 Journal Article Insights into the molecular flexibility of theta-defensins by NMR relaxation analysisConibear, Anne C., Wang, Conan K., Bi, Tao, Rosengren, K. Johan, Camarero, Julio A. and Craik, David J. (2014). Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis. Journal of Physical Chemistry B, 118 (49), 14257-14266. doi: 10.1021/jp507754c |
