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2010

Conference Publication

Characterisation of the human INSL5 solution structure

Haugaard-Kedstrom, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Craik, D. J., Wade, J. D. and Rosengren, K. J. (2010). Characterisation of the human INSL5 solution structure. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1303

Characterisation of the human INSL5 solution structure

2009

Journal Article

How bugs make lassos

Rosengren, K. J. and Craik, D. J. (2009). How bugs make lassos. Chemistry and Biology, 16 (12), 1211-1212. doi: 10.1016/j.chembiol.2009.12.004

How bugs make lassos

2009

Journal Article

Theoretical and computational strategies for rational molecularly imprinted polymer design

Nicholls, Ian A., Andersson, Hakan S., Charlton, Christy, Henschel, Henning, Karlsson, Bjorn C. G., Karlsson, Jesper G., O'Mahony, John, Rosengren, Annika M., Rosengren, K. Johan and Wikman, Susanne (2009). Theoretical and computational strategies for rational molecularly imprinted polymer design. Biosensors & Bioelectronics, 25 (3), 543-552. doi: 10.1016/j.bios.2009.03.038

Theoretical and computational strategies for rational molecularly imprinted polymer design

2009

Journal Article

Discovery, structure and biological activities of cyclotides

Daly, N.L ., Rosengren, K. J. and Craik, D. J. (2009). Discovery, structure and biological activities of cyclotides. Advanced Drug Delivery Reviews, 61 (11), 918-930. doi: 10.1016/j.addr.2009.05.003

Discovery, structure and biological activities of cyclotides

2009

Journal Article

The conserved glu in the cyclotide cycloviolacin O2 has a key structural role

Goransson, Ulf, Herrmann, Anders, Burman, Robert, Haugaard-Jonsson, Linda M. and Rosengren, K. Johan (2009). The conserved glu in the cyclotide cycloviolacin O2 has a key structural role. Chembiochem, 10 (14), 2354-2360. doi: 10.1002/cbic.200900342

The conserved glu in the cyclotide cycloviolacin O2 has a key structural role

2009

Journal Article

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework

Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Craik, David J., Wade, John D. and Rosengren, K. Johan (2009). Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework. Biochemical Journal, 419 (3), 619-627. doi: 10.1042/BJ20082353

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework

2009

Journal Article

Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold

Wang, C. K., Hu, S. H., Martin, J. L., Sjogren, T, Hajdu, J, Bohlin, L, Claeson, P, Goransson, U, Rosengren, K. J., Tang, J, Tan, N. H. and Craik, D. J. (2009). Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. Journal of Biological Chemistry, 284 (16), 10672-10683. doi: 10.1074/jbc.M900021200

Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold

2009

Conference Publication

Retrocyclin-2: A potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif

Daly, Norelle L., Yi, Chen K., Rosengren, K. Johan, Marx, Ute C., Phillips, Martin L., Waring, Alan J., Wang, Wei, Lehrer, Robert I. and Craik, David J. (2009). Retrocyclin-2: A potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif. 20th American Peptide Society Symposium, Montreal, Canada, 26-30 June 2007. New York, United States: Springer New York LLC. doi: 10.1007/978-0-387-73657-0_254

Retrocyclin-2: A potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif

2009

Book Chapter

NMR of peptide toxins

Rosengren, K. Johan, Daly, N. L. and Craik, D. J. (2009). NMR of peptide toxins. Annual reports on NMR Spectroscopy. (pp. 89-147) edited by Graham A. Webb. Oxford England U.K.: Academic Press Elsevier. doi: 10.1016/S0066-4103(09)06802-1

NMR of peptide toxins

2009

Conference Publication

Structural properties of relaxin chimeras: NMR characterization of the R3/I5 relaxin peptide

Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Wade, John D., Craik, David J. and Rosengren, K. Johan (2009). Structural properties of relaxin chimeras: NMR characterization of the R3/I5 relaxin peptide. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, 18-23 May, 2008. New York, U.S.A.: The Academy. doi: 10.1111/j.1749-6632.2008.03805.x

Structural properties of relaxin chimeras: NMR characterization of the R3/I5 relaxin peptide

2009

Journal Article

Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity

Hossain, Mohammed Akhter, Rosengren, K. Johan, Zhang, Suode, Bathgate, Ross A. D., Tregear, Geoffrey W., van Lierop, Bianca J., Robinson, Andrea J. and Wade, John D. (2009). Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity. Organic & Biomolecular Chemistry, 7 (8), 1547-1553. doi: 10.1039/b821882j

Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity

2009

Journal Article

The structural and functional role of the B-chain C-terminal arginine in the relaxin-3 peptide antagonist, R3(BΔ23-27)R/I5

Akhter Hossain, Mohammed, Bathgate, Ross A. D., Rosengren, K. Johan, Shabanpoor, Fazel, Zhang, Suode, Lin, Feng, Tregear, Geoffrey W. and Wade, John D. (2009). The structural and functional role of the B-chain C-terminal arginine in the relaxin-3 peptide antagonist, R3(BΔ23-27)R/I5. Chemical Biology and Drug Design, 73 (1), 46-52. doi: 10.1111/j.1747-0285.2008.00756.x

The structural and functional role of the B-chain C-terminal arginine in the relaxin-3 peptide antagonist, R3(BΔ23-27)R/I5

2009

Conference Publication

Structural insights into the function of relaxins

Rosengren, K. Johan, Bathgate, Ross A. D., Craik, David J., Daly, Norelle L., Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter and Wade, John D. (2009). Structural insights into the function of relaxins. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, 18-23 May, 2008. New York, U.S.A.: The Academy. doi: 10.1111/j.1749-6632.2009.03833.x

Structural insights into the function of relaxins

2009

Journal Article

NMR of Peptide Toxins

Rosengren, K. Johan, Daly, Norelle L. and Craik, David J. (2009). NMR of Peptide Toxins. Annual Reports on NMR Spectroscopy, 68 (C), 89-147. doi: 10.1016/S0066-4103(09)06802-1

NMR of Peptide Toxins

2008

Journal Article

Structure of the R3/I5 chimeric relaxin peptide, a selective GPCR135 and GPCR142 agonist

Haugaard-Jönsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Wade, John D., Craik, David J. and Rosengren, K. Johan (2008). Structure of the R3/I5 chimeric relaxin peptide, a selective GPCR135 and GPCR142 agonist. The Journal of Biological Chemistry, 283 (35), 23811-23818. doi: 10.1074/jbc.M800489200

Structure of the R3/I5 chimeric relaxin peptide, a selective GPCR135 and GPCR142 agonist

2008

Journal Article

Synthesis, conformation, and activity of human insulin-like Peptide 5 (INSL5)

Hossain, Mohammed Akhter, Bathgate, Ross A. D., Kong, Chze K., Shabanpoor, Fazel, Suode Zhang, Haugaard-Jönsson, Linda M., Rosengren, K. Johan, Tregear, Geoffrey W. and Wade, John D. (2008). Synthesis, conformation, and activity of human insulin-like Peptide 5 (INSL5). ChemBioChem, 9 (11), 1816-1822. doi: 10.1002/cbic.200800113

Synthesis, conformation, and activity of human insulin-like Peptide 5 (INSL5)

2008

Journal Article

The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors

Hossain, M. A., Rosengren, K. J., Haugaard-Jonsson, L. M., Zhang, S., Layfield, S., Ferraro, T., Daly, N. L., Tregear, G. W., Wade, J. D. and Bathgate, R. A. D. (2008). The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors. Journal of Biological Chemistry, 283 (25), 17287-17297. doi: 10.1074/jbc.M801911200

The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors

2008

Journal Article

Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity

Simonsen, S. M., Sando, L., Rosengren, K. J., Wang, C. K., Colgrave, M. L., Daly, N. L. and Craik, D. J. (2008). Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity. Journal of Biological Chemistry, 283 (15), 9805-9813. doi: 10.1074/jbc.M709303200

Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity

2008

Journal Article

In vitro assays of molecular motors: Impact of motor-surface interactions

Mansson, Alf, Balaz, Martina, Albet-Torres, Nuria and Rosengren, K Johan (2008). In vitro assays of molecular motors: Impact of motor-surface interactions. Frontiers In Bioscience, 13 (15), 5732-5754. doi: 10.2741/3112

In vitro assays of molecular motors: Impact of motor-surface interactions

2007

Journal Article

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

Daly, Norelle L., Chen, Y, Rosengren, KJ, Marx, UC, Phillips, ML, Waring, AJ, Wang, W, Lehrer, RI and Craik, David J. (2007). Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin. Biochemistry, 46 (35), 9920-9928. doi: 10.1021/bi700720e

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin