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2013 Journal Article Structural insights into the role of the cyclic backbone in a squash trypsin inhibitorDaly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begona, Martin, Jennifer L. and Craik, David J. (2013). Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 (50), 36141-36148. doi: 10.1074/jbc.M113.528240 |
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2013 Journal Article The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactionsRosengren, K. Johan, Daly, Norelle L., Harvey, Peta J. and Craik, David J. (2013). The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions. Peptide Science, Accepted Article (5), 1-16. doi: 10.1002/bip.22269 |
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2013 Journal Article The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activityConibear, Anne C., Rosengren, K. Johan, Daly, Norelle L., Henriques, Sonia Troeira and Craik, David J. (2013). The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. Journal of Biological Chemistry, 288 (15), 10830-10840. doi: 10.1074/jbc.M113.451047 |
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2013 Journal Article Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3Bathgate, Ross A. D., Oh, Maria H. Y., Ling, W. J. Jason, Kaas, Quentin, Hossain, M. Akhter, Gooley, Paul R. and Rosengren, K. Johan (2013). Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3. Frontiers in Endocrinology, 4 (FEB) article 13. doi: 10.3389/fendo.2013.00013 |
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2013 Journal Article Conopeptide p-tia defines a new allosteric site on the extracellular surface of the α1b-adrenoceptorRagnarsson, Lotten, Wang, Ching-I Anderson, Andersson, Asa, Fajarningsih, Dewi, Monks, Thea, Brust, Andreas, Rosengren, K. Johan and Lewis, Richard J. (2013). Conopeptide p-tia defines a new allosteric site on the extracellular surface of the α1b-adrenoceptor. Journal of Biological Chemistry, 288 (3), 1814-1827. doi: 10.1074/jbc.M112.430785 |
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2012 Journal Article Structural characterization of the cyclic cystine ladder motif of θ-defensinsConibear, Anne C., Rosengren, K. Johan, Harvey, Peta J. and Craik, David J. (2012). Structural characterization of the cyclic cystine ladder motif of θ-defensins. Biochemistry, 51 (48), 9718-9726. doi: 10.1021/bi301363a |
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2012 Journal Article The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2Scott, Daniel J., Rosengren, K. Johan and Bathgate, Ross A. D. (2012). The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2. Molecular Endocrinology, 26 (11), 1896-1906. doi: 10.1210/me.2012-1188 |
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2012 Journal Article Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxinChan, Linda J., Rosengren, K. Johan, Layfield, Sharon L., Bathgate, Ross A. D., Separovic, Frances, Samuel, Chrishan S., Hossain, Mohammed A. and Wade, John D. (2012). Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin. Journal of Biological Chemistry, 287 (49), 41152-41164. doi: 10.1074/jbc.M112.409284 |
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2012 Journal Article Circular proteins from plants and fungiGoransson, Ulf, Burman, Robert, Gunasekera, Sunithi, Stromstedt, Adam A. and Rosengren, K. Johan (2012). Circular proteins from plants and fungi. Journal of Biological Chemistry, 287 (32), 27001-27006. doi: 10.1074/jbc.R111.300129 |
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2012 Journal Article Extensive polymorphism in the porcine Toll-like receptor 10 geneBergman, I.-M., Edman, K., Ekdahl, K. N., Rosengren, K. J. and Edfors, I. (2012). Extensive polymorphism in the porcine Toll-like receptor 10 gene. International Journal of Immunogenetics, 39 (1), 68-76. doi: 10.1111/j.1744-313X.2011.01057.x |
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2012 Journal Article The structural determinants of insulin-like peptide 3 activityBathgate, Ross A. D., Zhang, Soude, Hughes, Richard A., Rosengren, K. Johan and Wade, John D. (2012). The structural determinants of insulin-like peptide 3 activity. Frontiers in Endocrinology, 3 (FEB) Article 11, 11.1-11.10. doi: 10.3389/fendo.2012.00011 |
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2012 Conference Publication Novel single-chain ligands for the relaxin-3 receptor RXFP3Rosengren, K. J., Haugaard-Kedstroem, L. M., Jones, M., Clark, R. J. and Bathgate, R. A. D. (2012). Novel single-chain ligands for the relaxin-3 receptor RXFP3. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448 |
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2012 Journal Article The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistanceAndersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3 |
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2012 Conference Publication The allosteric binding site for rho-TIA on the extracellular surface of the alpha 1B-AdrenoceptorRagnarsson, Lotten, Wang, Ching-I. Anderson, Andersson, Åsa, Fajarningsih, Dewi, Monks, Thea, Brust, Andreas, Rosengren, K. Johan and Lewis, Richard J. (2012). The allosteric binding site for rho-TIA on the extracellular surface of the alpha 1B-Adrenoceptor. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, 8-13 July 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.137 |
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2011 Journal Article The minimal active structure of human relaxin-2Hossain, Mohammed Akhter, Rosengren, K. Johan, Samuel, Chrishan S., Shabanpoor, Fazel, Chan, Linda J., Bathgate, Ross A. D. and Wade, John D. (2011). The minimal active structure of human relaxin-2. Journal of Biological Chemistry, 286 (43), 37555-37565. doi: 10.1074/jbc.M111.282194 |
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2011 Journal Article Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activitiesHenriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393 |
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2011 Journal Article The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutantWang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153 |
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2011 Journal Article Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j |
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2011 Journal Article NMR and protein structure in drug design: Application to cyclotides and conotoxinsDaly, Norelle L., Rosengren, K. Johan, Henriques, Sonia Troeira and Craik, David J. (2011). NMR and protein structure in drug design: Application to cyclotides and conotoxins. European Biophysics Journal, 40 (4), 359-370. doi: 10.1007/s00249-011-0672-9 |
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2011 Conference Publication Differences in bactericidal, hemolytic and anti-HIV efficiencies of the cyclotide kalata B1 are explained by distinct cell membrane compositionsHenriques, Sonia Troeira, Huang, Yen-Boa, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Second, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, I. David J. (2011). Differences in bactericidal, hemolytic and anti-HIV efficiencies of the cyclotide kalata B1 are explained by distinct cell membrane compositions. 22nd American Peptide Symposium, San Diego, California, 25-30 June 2011 . Hoboken, NJ, United States: John Wiley & Sons. |
