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2012

Journal Article

Structural characterization of the cyclic cystine ladder motif of θ-defensins

Conibear, Anne C., Rosengren, K. Johan, Harvey, Peta J. and Craik, David J. (2012). Structural characterization of the cyclic cystine ladder motif of θ-defensins. Biochemistry, 51 (48), 9718-9726. doi: 10.1021/bi301363a

Structural characterization of the cyclic cystine ladder motif of θ-defensins

2012

Journal Article

The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2

Scott, Daniel J., Rosengren, K. Johan and Bathgate, Ross A. D. (2012). The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2. Molecular Endocrinology, 26 (11), 1896-1906. doi: 10.1210/me.2012-1188

The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2

2012

Journal Article

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin

Chan, Linda J., Rosengren, K. Johan, Layfield, Sharon L., Bathgate, Ross A. D., Separovic, Frances, Samuel, Chrishan S., Hossain, Mohammed A. and Wade, John D. (2012). Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin. Journal of Biological Chemistry, 287 (49), 41152-41164. doi: 10.1074/jbc.M112.409284

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin

2012

Journal Article

Circular proteins from plants and fungi

Goransson, Ulf, Burman, Robert, Gunasekera, Sunithi, Stromstedt, Adam A. and Rosengren, K. Johan (2012). Circular proteins from plants and fungi. Journal of Biological Chemistry, 287 (32), 27001-27006. doi: 10.1074/jbc.R111.300129

Circular proteins from plants and fungi

2012

Journal Article

Extensive polymorphism in the porcine Toll-like receptor 10 gene

Bergman, I.-M., Edman, K., Ekdahl, K. N., Rosengren, K. J. and Edfors, I. (2012). Extensive polymorphism in the porcine Toll-like receptor 10 gene. International Journal of Immunogenetics, 39 (1), 68-76. doi: 10.1111/j.1744-313X.2011.01057.x

Extensive polymorphism in the porcine Toll-like receptor 10 gene

2012

Journal Article

The structural determinants of insulin-like peptide 3 activity

Bathgate, Ross A. D., Zhang, Soude, Hughes, Richard A., Rosengren, K. Johan and Wade, John D. (2012). The structural determinants of insulin-like peptide 3 activity. Frontiers in Endocrinology, 3 (FEB) Article 11, 11.1-11.10. doi: 10.3389/fendo.2012.00011

The structural determinants of insulin-like peptide 3 activity

2012

Conference Publication

Novel single-chain ligands for the relaxin-3 receptor RXFP3

Rosengren, K. J., Haugaard-Kedstroem, L. M., Jones, M., Clark, R. J. and Bathgate, R. A. D. (2012). Novel single-chain ligands for the relaxin-3 receptor RXFP3. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448

Novel single-chain ligands for the relaxin-3 receptor RXFP3

2012

Journal Article

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

Andersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

2012

Conference Publication

The allosteric binding site for rho-TIA on the extracellular surface of the alpha 1B-Adrenoceptor

Ragnarsson, Lotten, Wang, Ching-I. Anderson, Andersson, Åsa, Fajarningsih, Dewi, Monks, Thea, Brust, Andreas, Rosengren, K. Johan and Lewis, Richard J. (2012). The allosteric binding site for rho-TIA on the extracellular surface of the alpha 1B-Adrenoceptor. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, 8-13 July 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.137

The allosteric binding site for rho-TIA on the extracellular surface of the alpha 1B-Adrenoceptor

2011

Journal Article

The minimal active structure of human relaxin-2

Hossain, Mohammed Akhter, Rosengren, K. Johan, Samuel, Chrishan S., Shabanpoor, Fazel, Chan, Linda J., Bathgate, Ross A. D. and Wade, John D. (2011). The minimal active structure of human relaxin-2. Journal of Biological Chemistry, 286 (43), 37555-37565. doi: 10.1074/jbc.M111.282194

The minimal active structure of human relaxin-2

2011

Journal Article

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Henriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

2011

Journal Article

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

Wang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

2011

Journal Article

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

2011

Journal Article

NMR and protein structure in drug design: Application to cyclotides and conotoxins

Daly, Norelle L., Rosengren, K. Johan, Henriques, Sonia Troeira and Craik, David J. (2011). NMR and protein structure in drug design: Application to cyclotides and conotoxins. European Biophysics Journal, 40 (4), 359-370. doi: 10.1007/s00249-011-0672-9

NMR and protein structure in drug design: Application to cyclotides and conotoxins

2011

Conference Publication

Differences in bactericidal, hemolytic and anti-HIV efficiencies of the cyclotide kalata B1 are explained by distinct cell membrane compositions

Henriques, Sonia Troeira, Huang, Yen-Boa, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Second, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, I. David J. (2011). Differences in bactericidal, hemolytic and anti-HIV efficiencies of the cyclotide kalata B1 are explained by distinct cell membrane compositions. 22nd American Peptide Symposium, San Diego, California, 25-30 June 2011 . Hoboken, NJ, United States: John Wiley & Sons.

Differences in bactericidal, hemolytic and anti-HIV efficiencies of the cyclotide kalata B1 are explained by distinct cell membrane compositions

2010

Journal Article

Peptide rope tricks

Rosengren, K. Johan and Craik, David J. (2010). Peptide rope tricks. Chimica Oggi, 28 (6), 28-32.

Peptide rope tricks

2010

Conference Publication

Structural characterization of the relaxin-3IINSL5 chimera peptide: A selective RXFP3 and RXFP4 agonist

Haugaard-Kedström, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Wade, J. D., Craik, D. J. and Rosengren, K. J. (2010). Structural characterization of the relaxin-3IINSL5 chimera peptide: A selective RXFP3 and RXFP4 agonist. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1301

Structural characterization of the relaxin-3IINSL5 chimera peptide: A selective RXFP3 and RXFP4 agonist

2010

Journal Article

Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis

Plan, Manuel R, Rosengren, K Johan, Sando, Lillian, Daly, Norelle L and Craik, David J (2010). Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis. Biopolymers, 94 (5), 647-658. doi: 10.1002/bip.21409

Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis

2010

Journal Article

European wild boars and domestic pigs display different polymorphic patterns in the Toll-like receptor (TLR) 1, TLR2, and TLR6 genes

Bergman, Ingrid-Maria, Rosengren, Johan K., Edman, Kjell and Edfors, Inger (2010). European wild boars and domestic pigs display different polymorphic patterns in the Toll-like receptor (TLR) 1, TLR2, and TLR6 genes. Immunogenetics, 62 (1), 49-52. doi: 10.1007/s00251-009-0409-4

European wild boars and domestic pigs display different polymorphic patterns in the Toll-like receptor (TLR) 1, TLR2, and TLR6 genes

2010

Conference Publication

Characterisation of the human INSL5 solution structure

Haugaard-Kedstrom, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Craik, D. J., Wade, J. D. and Rosengren, K. J. (2010). Characterisation of the human INSL5 solution structure. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1303

Characterisation of the human INSL5 solution structure