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2012 Journal Article Seventy-five genetic loci influencing the human red blood cellvan der Harst, Pim, Zhang, Weihua, Leach, Irene Mateo, Rendon, Augusto, Verweij, Niek, Sehmi, Joban, Paul, Dirk S., Elling, Ulrich, Allayee, Hooman, Li, Xinzhong, Radhakrishnan, Aparna, Tan, Sian-Tsung, Voss, Katrin, Weichenberger, Christian X., Albers, Cornelis A., Al-Hussani, Abtehale, Asselbergs, Folkert W., Ciullo, Marina, Danjou, Fabrice, Dina, Christian, Esko, Tonu, Evans, David M., Franke, Lude, Goegele, Martin, Hartiala, Jaana, Hersch, Micha, Holm, Hilma, Hottenga, Jouke-Jan, Kanoni, Stavroula ... Chambers, John C. (2012). Seventy-five genetic loci influencing the human red blood cell. Nature, 492 (7429), 369-375. doi: 10.1038/nature11677 |
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2012 Journal Article Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysisTansey, Katherine E., Guipponi, Michel, Perroud, Nader, Bondolfi, Guido, Domenici, Enrico, Evans, David, Hall, Stephanie K., Hauser, Joanna, Henigsberg, Neven, Hu, Xiaolan, Jerman, Borut, Maier, Wolfgang, Mors, Ole, O'Donovan, Michael, Peters, Tim J., Placentino, Anna, Rietschel, Marcella, Souery, Daniel, Aitchison, Katherine J., Craig, Ian, Farmer, Anne, Wendland, Jens R., Malafosse, Alain, Holmans, Peter, Lewis, Glyn, Lewis, Cathryn M., Stensbøl, Tine Bryan, Kapur, Shitij, McGuffin, Peter and Uher, Rudolf (2012). Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis. PLoS Medicine, 9 (10) e1001326, e1001326. doi: 10.1371/journal.pmed.1001326 |
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2012 Journal Article WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture riskZheng, Hou-Feng, Tobias, Jon H., Duncan, Emma, Evans, David M., Eriksson, Joel, Paternoster, Lavinia, Yerges-Armstrong, Laura M., Lehtimaki, Terho, Bergstrom, Ulrica, Kahonen, Mika, Leo, Paul J., Raitakari, Olli, Laaksonen, Marika, Nicholson, Geoffrey C., Viikari, Jorma, Ladouceur, Martin, Lyytikainen, Leo-Pekka, Medina-Gomez, Carolina, Rivadeneira, Fernando, Prince, Richard L., Sievanen, Harri, Leslie, William D., Mellstrom, Dan, Eisman, John A., Moverare-Skrtic, Sofia, Goltzman, David, Hanley, David A., Jones, Graeme, Pourcain, Beate St. ... Lorentzon, Mattias (2012). WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. Plos Genetics, 8 (7) e1002745, e1002745.1-e1002745.13. doi: 10.1371/journal.pgen.1002745 |
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2012 Journal Article Power calculations in genetic studiesEvans, David M. and Purcell, Shaun (2012). Power calculations in genetic studies. Cold Spring Harbor Protocols, 7 (6), 664-674. doi: 10.1101/pdb.top069559 |
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2012 Journal Article Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis?Joshi, Reeti, Reveille, John D., Brown, Matthew A., Weisman, Michael H., Ward, Michael M., Gensler, Lianne S., Wordsworth, B. Paul, Evans, David M. and Assassi, Shervin (2012). Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis?. Arthritis Care and Research, 64 (5), 780-784. doi: 10.1002/acr.21601 |
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2012 Journal Article A genome-wide association meta-analysis identifies new childhood obesity lociBradfield, Jonathan P., Taal, H. Rob, Timpson, Nicholas J., Scherag, André, Lecoeur, Cecile, Warrington, Nicole M., Hypponen, Elina, Holst, Claus, Valcarcel, Beatriz, Thiering, Elisabeth, Salem, Rany M., Schumacher, Fredrick R., Cousminer, Diana L., Sleiman, Patrick M. A., Zhao, Jianhua, Berkowitz, Robert I., Vimaleswaran, Karani S., Jarick, Ivonne, Pennell, Craig E., Evans, David M., St Pourcain, Beate, Berry, Diane J., Mook-Kanamori, Dennis O., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., van Duijn, Cornelia M., van der Valk, Ralf J. P., de Jongste, Johan C. ... Grant, Struan F. A. (2012). A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genetics, 44 (5), 526-531. doi: 10.1038/ng.2247 |
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2012 Journal Article Common variants at 12q15 and 12q24 are associated with infant head circumferenceTaal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Møller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Mònica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bønnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., Kim, Cecilia E., Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Middeldorp, Christel (2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, 44 (5), 532-538. doi: 10.1038/ng.2238 |
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2012 Journal Article Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fractureEstrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma L., Ntzani, Evangelia E., Oei, Ling, Albagha, Omar M. E., Amin, Najaf, Kemp, John P., Koller, Daniel L., Li, Guo, Liu, Ching-Ti, Minster, Ryan L., Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Yerges-Armstrong, Laura M., Zheng, Hou-Feng, Alonso, Nerea, Eriksson, Joel, Kammerer, Candace M., Kaptoge, Stephen K., Leo, Paul J., Thorleifsson, Gudmar, Wilson, Scott G., Wilson, James F., Aalto, Ville ... Rivadeneira, Fernando (2012). Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics, 44 (5), 491-501. doi: 10.1038/ng.2249 |
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2012 Journal Article Patterns of Cis regulatory variation in diverse human populationsStranger, Barbara E., Montgomery, Stephen B., Dimas, Antigone S., Parts, Leopold, Stegle, Oliver, Ingle, Catherine E., Sekowska, Magda, Smith, George Davey, Evans, David, Gutierrez-Arcelus, Maria, Price, Alkes, Raj, Towfique, Nisbett, James, Nica, Alexandra C., Beazley, Claude, Durbin, Richard, Deloukas, Panos and Dermitzakis, Emmanouil T. (2012). Patterns of Cis regulatory variation in diverse human populations. PLoS Genetics, 8 (4) e1002639, e1002639-284. doi: 10.1371/journal.pgen.1002639 |
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2012 Journal Article Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individualsDastani, Zari, Hivert, Marie-France, Timpson, Nicholas, Perry, John R. B., Yuan, Xin, Scott, Robert A., Henneman, Peter, Heid, Iris M., Kizer, Jorge R., Lyytikäinen, Leo-Pekka, Fuchsberger, Christian, Tanaka, Toshiko, Morris, Andrew P., Small, Kerrin, Isaacs, Aaron, Beekman, Marian, Coassin, Stefan, Lohman, Kurt, Qi, Lu, Kanoni, Stavroula, Pankow, James S., Uh, Hae-Won, Wu, Ying, Bidulescu, Aurelian, Rasmussen-Torvik, Laura J., Greenwood, Celia M. T., Ladouceur, Martin, Grimsby, Jonna, Manning, Alisa K. ... MuTHER Consortium (2012). Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals. PloS Genetics, 8 (3) e1002607, e1002607.1-e1002607.23. doi: 10.1371/journal.pgen.1002607 |
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2012 Journal Article Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion positionPaternoster, Lavinia, Zhurov, Alexei I., Toma, Arshed M., Kemp, John P., St. Pourcain, Beate, Timpson, Nicholas J., McMahon, George, McArdle, Wendy, Ring, Susan M., Smith, George Davey, Richmond, Stephen and Evans, David M. (2012). Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position. American Journal of Human Genetics, 90 (3), 478-485. doi: 10.1016/j.ajhg.2011.12.021 |
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2012 Journal Article Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohortsBoraska, Vesna, Day-Williams, Aaron, Franklin, Christopher S., Elliott, Katherine S., Panoutsopoulou, Kalliope, Tachmazidou, Ioanna, Albrecht, Eva, Bandinelli, Stefania, Beilin, Lawrence J., Bochud, Murielle, Cadby, Gemma, Ernst, Florian, Evans, David M., Hayward, Caroline, Hicks, Andrew A., Huffman, Jennifer, Huth, Cornelia, James, Alan L., Klopp, Norman, Kolcic, Ivana, Kutalik, Zoltan, Lawlor, Debbie A., Musk, Arthur W., Pehlic, Marina, Pennell, Craig E., Perry, John R. B., Peters, Annette, Polasek, Ozren, St Pourcain, Beate ... Zeggini, Eleftheria (2012). Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohorts. Plos One, 7 (3) e31369, e31369.1-e31369.10. doi: 10.1371/journal.pone.0031369 |
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2012 Journal Article Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and humanIchimura, Atsuhiko, Hirasawa, Akira, Poulain-Godefroy, Odile, Bonnefond, Amelie, Hara, Takafumi, Yengo, Loic, Kimura, Ikuo, Leloire, Audrey, Liu, Ning, Iida, Keiko, Choquet, Helene, Besnard, Philippe, Lecoeur, Cecile, Vivequin, Sidonie, Ayukawa, Kumiko, Takeuchi, Masato, Ozawa, Kentaro, Tauber, Maithe, Maffeis, Claudio, Morandi, Anita, Buzzetti, Raffaella, Elliott, Paul, Pouta, Anneli, Jarvelin, Marjo-Riitta, Koerner, Antje, Kiess, Wieland, Pigeyre, Marie, Caiazzo, Roberto, Van Hul, Wim ... Froguel, Philippe (2012). Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature, 483 (7389), 350-354. doi: 10.1038/nature10798 |
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2012 Journal Article Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitisPaternoster, Lavinia, Standl, Marie, Chen, Chi-Mei, Ramasamy, Adaikalavan, Bonnelykke, Klaus, Duijts, Liesbeth, Ferreira, Manuel A., Alves, Alexessander C., Thyssen, Jacob P., Albrecht, Eva, Baurecht, Hansjorg, Feenstra, Bjarke, Sleiman, Patrick M. A., Hysi, Piro, Warrington, Nicole M., Curjuric, Ivan, Myhre, Ronny, Curtin, John A., Groen-Blokhuis, Maria M., Kerkhof, Marjan, Saaf, Annika, Franke, Andre, Ellinghaus, David, Folster-Holst, Regina, Dermitzakis, Emmanouil, Montgomery, Stephen B., Prokisch, Holger, Heim, Katharina, Hartikainen, Anna-Lisa ... EArly Genetics Lifecourse Epidemiology (EAGLE) Consortium (2012). Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nature Genetics, 44 (2), 187-192. doi: 10.1038/ng.1017 |
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2012 Journal Article Molecular and population analysis of natural selection on the human haptoglobin duplicationRodriguez, Santiago, Williams, Dylan M., Guthrie, Philip A. I., Mcardle, Wendy L., Smith, George Davey, Evans, David M., Gaunt, Tom R. and Day, Ian N. M. (2012). Molecular and population analysis of natural selection on the human haptoglobin duplication. Annals of Human Genetics, 76 (5), 352-362. doi: 10.1111/j.1469-1809.2012.00716.x |
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2012 Conference Publication A genomewide association study of anterior uveitiClaushuis, Dorith, Cortes, Adrian, Bradbury, Linda A., Martin, Tammy M., Rosenbaum, James T., Reveille, John D., Wordsworth, Paul, Pointon, Jennifer, Evans, David, Leo, Paul, Mukhopadhyay, Pamela and Brown, Matthew A. (2012). A genomewide association study of anterior uveiti. Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), Washington, DC, United States, 9-14 November 2012. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.37735 |
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2012 Conference Publication A Genome-Wide Association Meta-Analysis and a Mouse Gene Deletion Model Identify Wnt16 as a Potential Regulator of Cortical Bone ThicknessTobias, Jonathan, Ohlsson, Claes, Paternoster, Lavinia, Lehtimaki, Terho, Kahonen, Mika, Raitakari, Olli, Laaksonen, Marika, Viikari, Jorma, Mellstrom, Dan, Moverare-Skitric, Sofia, Karlsson, Magnus, Ljunggren, Osten, Kemp, John P., Nethander, Maria, Vandenput, Liesbeth, Brommage, Robert, Liu, Jeff, Evans, David M. and Lorentzon, Mattias (2012). A Genome-Wide Association Meta-Analysis and a Mouse Gene Deletion Model Identify Wnt16 as a Potential Regulator of Cortical Bone Thickness. Osteoporosis and Bone Conference, Manchester England, Jul 01-04, 2012. LONDON: SPRINGER LONDON LTD. |
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2012 Journal Article Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohortSpycher, Ben D., Henderson, John, Granell, Raquel, Evans, David M., Smith, George Davey, Timpson, Nicholas J. and Sterne, Jonathan A. C. (2012). Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort. Journal of Allergy and Clinical Immunology, 130 (2), 503-509.e7. doi: 10.1016/j.jaci.2012.06.002 |
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2012 Conference Publication A genomewide association study of anterior uveitisClaushuis, T., Cortes, A., Bradbury, L. A., Martin, T. M., Rosenbaum, J. T., Reveille, J. D., Pointon, J. J., Wordsworth, B. P., Evans, D. M., Leo, P., Mukhopadhyay, P. and Brown, M. A. (2012). A genomewide association study of anterior uveitis. 8th International Congress on Spondyloarthritis, Granada, Spain, 9-13 May 2012. Ospedaletto, Italy: Pacini Editore SpA. |
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2012 Journal Article Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locusMedina-Gomez, Carolina, Kemp, John P., Estrada, Karol, Eriksson, Joel, Liu, Jeff, Reppe, Sjur, Evans, David M., Heppe, Denise H. M., Vandenput, Liesbeth, Herrera, Lizbeth, Ring, Susan M., Kruithof, Claudia J., Timpson, Nicholas J., Zillikens, M.C., Olstad, Ole K., Zheng, Hou-Feng, Richards, J. Brent, St. Pourcain, Beate, Hofman, Albert, Jaddoe, Vincent W. V., Smith, George Davey, Lorentzon, Mattias, Gautvik, Kaare M., Uitterlinden, Andre G., Brommage, Robert, Ohlsson, Claes, Tobias, Jonathan H. and Rivadeneira, Fernando (2012). Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genetics, 8 (7) e1002718, e1002718.1-e1002718.14. doi: 10.1371/journal.pgen.1002718 |
