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2011 Conference Publication Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activityEstrada, K, Evangelou, E, Hsu, YH, Styrkarsdottir, U, Liu, CT, Moayyeri, A, Kaptoge, S, Duncan, E, Amin, N, Kiel, D, Karasik, D, Albagha, OM, Brown, M, Spector, TD, Zillikens, MC, Ohlsson, C, Thorleifsson, G, Reeve, J, Vandenput, L, Pettersson, U, O'Neill, T, Riancho, JA, Ijunggren, O, Rousseau, F, Leslie, WD, Obermayer-Pietsch, B, Alonso, N, Langdahl, B, Nogues, X ... GENOMOS Consortia (2011). Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity. 3rd Joint Meeting of the European-Calcified-Tissue-Society/International-Bone-and-Mineral-Society, Athens Greece, May 07-11, 2011. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.bone.2011.03.070 |
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2011 Journal Article A genome-wide association study to identify genetic determinants of atopy in subjects from the United KingdomWan, Yize I., Strachan, David P., Evans, David M., Henderson, John, McKeever, Tricia, Holloway, John W., Hall, Ian P. and Sayers, Ian (2011). A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom. Journal of Allergy and Clinical Immunology, 127 (1), 223-231. doi: 10.1016/j.jaci.2010.10.006 |
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2010 Conference Publication The genetic basis of spondyloarthritis: SPARTAN/IGAS 2009Evans, David M., Reveille, John D., Brown, Matthew A., Chandran, Vinod, Gladman, Dafna D., Martin, Tammy M., McGovern, Dermot, Wordsworth, Paul and Inman, Robert D. (2010). The genetic basis of spondyloarthritis: SPARTAN/IGAS 2009. Toronto, ON, Canada: Journal of Rheumatology Publishing. doi: 10.3899/jrheum.100892 |
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2010 Journal Article A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1Strange, Amy, Capon, Francesca, Spencer, Chris C. A., Knight, Jo, Weale, Michael E., Allen, Michael H., Barton, Anne, Band, Gavin, Bellenguez, Céline, Bergboer, Judith G. M., Blackwell, Jenefer M., Bramon, Elvira, Bumpstead, Suzannah J., Casas, Juan P., Cork, Michael J., Corvin, Aiden, Deloukas, Panos, Dilthey, Alexander, Duncanson, Audrey, Edkins, Sarah, Estivill, Xavier, Fitzgerald, Oliver, Freeman, Colin, Giardina, Emiliano, Gray, Emma, Hofer, Angelika, Hüffmeier, Ulrike, Hunt, Sarah E., Irvine, Alan D. ... Trembath, Richard C. (2010). A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nature Genetics, 42 (11), 985-990. doi: 10.1038/ng.694 |
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2010 Journal Article Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP studyNewby, Paul R., Pickles, Oliver J., Mazumdar, Samaresh, Brand, Oliver J., Carr-Smith, Jaqueline D., Pearce, Simon H. S., Franklyn, Jayne A., Wellcome Trust Case Control Consortium, Evans, David M., Simmonds, Matthew J., Gough, Stephen C. L., Brown, Matthew A., Bradbury, Linda and Pointon, Jennifer (2010). Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study. European Journal of Human Genetics, 18 (9), 1021-1026. doi: 10.1038/ejhg.2010.55 |
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2010 Journal Article A variant in LIN28B is Associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposureMedland, Sarah E., Zayats,Tetyana, Glaser, Beate, Nyholt, Dale R., Gordon,Scott D., Wright, Margaret J., Montgomery, Grant W., Campbell, Megan J., Henders, Anjali K., Timpson, Nicholas J., Peltonen, Leena, Wolke, Dieter, Ring, Susan M., Deloukas, Panos, Martin, Nicholas G., Smith, George Davey and Evans, David M. (2010). A variant in LIN28B is Associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. American Journal of Human Genetics, 86 (4), 519-525. doi: 10.1016/j.ajhg.2010.02.017 |
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2010 Journal Article Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controlsCraddock, Nick, Hurles, Matthew E., Cardin, Niall, Pearson, Richard D., Plagnol, Vincent, Robson, Samuel, Vukcevic, Damjan, Barnes, Chris, Brown, Matthew A., Evans, David M. and The Wellcome Trust Case Control Consortium (2010). Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464 (7289), 713-720. doi: 10.1038/nature08979 |
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2010 Journal Article Functional Gene Group Analysis Reveals a Role of Synaptic Heterotrimeric G Proteins in Cognitive AbilityRuano, Dina, Abecasis, Goncalo R., Glaser, Beate, Lips, Esther S., Cornelisse, L. Niels, de Jong, Arthur P. H., Evans, David M., Smith, George Davey, Timpson, Nicolas J., Smit, August B., Heutink, Peter, Verhage, Mathhijs and Posthuma, Danielle (2010). Functional Gene Group Analysis Reveals a Role of Synaptic Heterotrimeric G Proteins in Cognitive Ability. American Journal of Human Genetics, 86 (2), 113-125. doi: 10.1016/j.ajhg.2009.12.006 |
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2010 Journal Article A new highly penetrant form of obesity due to deletions on chromosome 16p11.2Walters, R. G., Jacquemont, S., Valsesia, A., De Smith, A. J., Martinet, D., Andersson, J., Falchi, M., Chen, F., Andrieux, J., Lobbens, S., Delobel, B., Stutzmann, F., El-Sayed Moustafa, J. S., Chevre, J.-C., Lecoeur, C., Vatin, V., Bouquillon, S., Buxton, J. L., Boute, O., Holder-Espinasse, M., Cuisset, J.-M., Lemaitre, M.-P., Ambresin, A.-E., Brioschi, A., Gaillard, M., Giusti, V., Fellmann, F., Ferrarini, A., Hadjikhani, N. ... Beckmann, J. S. (2010). A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature, 463 (7281), 671-675. doi: 10.1038/nature08727 |
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2010 Journal Article Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility lociReveille, John D., Sims, Anne-Marie, Danoy, Patrick, Evans, David M., Leo, Paul, Pointon, Jennifer J., Jin, Rui, Zhou, Xiaodong, Bradbury, Linda A., Appleton, Louise H., Davis, John C., Diekman, Laura, Doan, Tracey, Dowling, Alison, Duan, Ran, Duncan, Emma L., Farrar, Claire, Hadler, Johanna, Harvey, David, Karaderi, Tugce, Mogg, Rebecca, Pomeroy, Emma, Pryce, Karena, Taylor, Jacqueline, Savage, Laurie, Deloukas, Panos, Kumanduri, Vasudev, Peltonen, Leena, Ring, Sue M. ... Brown, Mathew A. (2010). Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nature Genetics, 42 (2), 123-127. doi: 10.1038/ng.513 |
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2010 Journal Article Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune controlFerreira, Mar, Mangino, M, Brumme, CJ, Zhao, ZZ, Medland, SE, Wright, MJ, Nyholt, DR, Gordon, S, Campbell, M, McEvoy, BP, Henders, A, Evans, DM, Lanchbury, JS, Pereyra, F, Walker, BD, Haas, DW, Soranzo, N, Spector, TD, de Bakker, PIW, Frazer, IH, Montgomery, GW, Martin, NG and Int HIV Controllers Study (2010). Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control. American Journal of Human Genetics, 86 (1), 88-92. doi: 10.1016/j.ajhg.2009.12.008 |
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2010 Journal Article Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weightFreathy, Rachel M., Mook-Kanamor, Dennis O., Sovio, Ulla, Prokopenko, Inga, Timpson, Nicholas J., Berry, Diane J., Warrington, Nicole M., Widen, Elisabeth, Hottenga, Jouke Jan, Kaakinen, Marika, Lange, Leslie A., Bradfield, Jonathan P., Kerkhof, Marjan, Marsh, Julie A., Magi, Reedik, Chen, Chih-Mei, Lyon, Helen N., Kirin, Mirna, Adair, Linda S., Aulchenko, Yurii S., Bennett, Amanda J., Borja, Judith B., Bouatia-Naji, Nabila, Charoen, Pimphen, Coin, Lachlan ..J. M., Cousminer, Diana L., De Geus, Eco J. C., Deloukas, Panos, Elliott, Paul ... McCarthy, Mark I. (2010). Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics, 42 (5), 430-435. doi: 10.1038/ng.567 |
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2010 Journal Article OPG and RANK polymorphisms are both associated with cortical bone mineral density: Findings from a metaanalysis of the avon longitudinal study of parents and children and Gothenburg osteoporosis and obesity determinants cohortsPaternoster, L., Ohlsson, C., Sayers, A., Vandenput, L., Lorentzon, M., Evans, D. M. and Tobias, J. H. (2010). OPG and RANK polymorphisms are both associated with cortical bone mineral density: Findings from a metaanalysis of the avon longitudinal study of parents and children and Gothenburg osteoporosis and obesity determinants cohorts. Journal of Clinical Endocrinology and Metabolism, 95 (8), 3940-3948. doi: 10.1210/jc.2010-0025 |
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2010 Journal Article Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential Pleiotropic effects on bonePaternoster, Lavinia, Lorentzon, Mattias, Vandenput, Liesbeth, Karlsson, Magnus K., Ljunggren, Osten, Kindmark, Andreas, Mellstrom, Dan, Kemp, John P., Jarett, Caroline E., Holly, Jeff M. P., Sayers, Adrian, St. Pourcain, Beate, Timpson, Nicholas J., Deloukas, Panos, Smith, George Davey, Ring, Ssusan M., Evans, David M., Tobias, Jon H. and Ohlsson, Claes (2010). Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential Pleiotropic effects on bone. PLoS Genetics, 6 (11) e1001217, e1001217.1-e1001217.12. doi: 10.1371/journal.pgen.1001217 |
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2010 Journal Article Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopyBouzigon, Emmanuelle, Forabosco, Paola, Koppelman, Gerard H., Cookson, William O. C. M., Dizier, Marie-Helene, Duffy, David L., Evans, David M., Ferreira, Manuel A. R., Kere, Juha, Laitinen, Tarja, Malerba, Giovanni, Meyers, Deborah A., Moffatt, Miriam, Martin, Nicholas G, Ng, Mandy Y., Pignatti, Pier Franco, Wjst, Mathias, Kauffmann, Francine, Demenais, Florence and Lewis, Cathryn M. (2010). Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy. European Journal of Human Genetics, 18 (6), 700-706. doi: 10.1038/ejhg.2009.224 |
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2010 Journal Article Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individualsHeid, Iris M., Henneman, Peter, Hicks, Andrew, Coassin, Stefan, Winkler, Thomas, Aulchenko, Yurii S., Fuchsberger, Christian, Song, Kijoung, Hivert, Marie-France, Waterworth, Dawn M., Timpson, Nicholas J., Richards, J. Brent, Perry, John R. B., Tanaka, Toshiko, Amin, Najaf, Kollerits, Barbara, Pichler, Irene, Oostra, Ben A., Thorand, Barbara, Frants, Rune R., Illig, Thomas, Dupuis, Josée, Glaser, Beate, Spector, Tim, Guralnik, Jack, Egan, Josephine M., Florez, Jose C., Evans, David M., Soranzo, Nicole ... van Duijn, Cornelia M. (2010). Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis, 208 (2), 412-420. doi: 10.1016/j.atherosclerosis.2009.11.035 |
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2010 Journal Article Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studiesSarwar, N., Sandhu, M. S., Ricketts, S. L., Butterworth, Adam S., Di Angelantonio, Emanuele, Matthijs Boekholdt, S., Ouwehand, W., Watkins, H., Samani, N. J., Saleheen, D., Lawlor, Debbie, Reilly, Muredach P., Hingorani, A. D., Talmud, P. J., Danesh, J., Braund, P. S., Hall, A. S., Thompson, J., Marz, W., Trip, M., Lawlor, D. A., Casas, J. P., Ebrahim, S., Arsenault, B. J., Boekholdt, S. M., Khaw, K. T., Wareham, N. J., Grallert, H., Illig, T. ... Wood, A. M. (2010). Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studies. The Lancet, 375 (9726), 1634-1639. doi: 10.1016/S0140-6736(10)60545-4 |
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2010 Journal Article Genome-wide association study reveals multiple loci associated with primary tooth development during infancyPillas, Demetris, Hoggart, Clive J., Evans, David M., O'Reilly, Paul F., Sipila, Kirsi, Lahdesmaki, Raija, Millwood, Iona Y., Kaakinen, Marika., Netuveli, Gopalakrishnan, Blane, David, Charoen, Pimphen, Sovio, Ulla, Pouta, Anneli, Freimer, Nelson, Hartikainen, Anna-Lisa., Laitinen, Jaana, Vaara, Sarianna, Glaser, Beate, Crawford, Peter, Timpson, Nicholas J., Ring, Susan M., Deng, Guohong, Zhang, Weihua, McCarthy, Mark I., Deloukas, Panos, Peltonen, Leena, Elliott, Paul, Coin, Lachlan J. M., Smith, George D. and Jarvelin, Marjo-Riita (2010). Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. PLoS Genetics, 6 (2) e1000856, e1000856.1-e1000856.7. doi: 10.1371/journal.pgen.1000856 |
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2009 Journal Article Genome-wide association study identifies five loci associated with lung functionRepapi, E., Sayers, I., Wain, L. V., Burton, P. R., Johnson, T., Obeidat, M., Zhao, J. H., Ramasamy, A., Evans, David M., Wellcome Trust Case Control Consortium, Brown, Matthew A. and Bradbury, Linda (2009). Genome-wide association study identifies five loci associated with lung function. Nature Genetics, 42 (1), 36-45. doi: 10.1038/ng.501 |
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2009 Journal Article Investigating the genetic association between ERAP1 and ankylosing spondylitisHarvey, David, Pointon, Jennifer J., Evans, David M., Karaderi, Tugce, Farrar, Claire, Appleton, Louise H., Sturrock, Roger D., Stone, Millicent A., Oppermann, Udo, Brown, Matthew A. and Wordsworth, B. Paul (2009). Investigating the genetic association between ERAP1 and ankylosing spondylitis. Human Molecular Genetics, 18 (21), 4204-4212. doi: 10.1093/hmg/ddp371 |
