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2009

Journal Article

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Willer, Cristen J., Speliotes, Elizabeth K., Loos, Ruth J. F., Li, Shengxu, Lindgren, Cecilia M., Heid, Iris M., Berndt, Sonja I., Elliot, Amanda L., Jackson, Anne U., Lamina, Claudia, Lettre, Guillaume, Lim, Noha, Lyon, Helen N., McCarroll, Steven N., Papadakis, Konstantinos, Qi, Lu, Randall, Joshua C., Roccasecca, Rosa Maria, Sanna, Serena, Scheet, Paul, Weedon, Michael N., Wheeler, Eleanor, Zhao, Jing Hua, Jacobs, Leonie C., Prokopenko,, Soranzo, Nicole, Tanaka, Toshiko, Timpson, Nicholas J., Almgran, Peter ... GIANT consortium (2009). Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics, 41 (1), 25-34. doi: 10.1038/ng.287

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

2008

Journal Article

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Barrett, Jeffrey C., Wellcome Trust Case Control Consortium, Brown, Matthew A., Bradbury, Linda A., et al. and Evans, David (2008). Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nature Genetics, 40 (8), 955-962. doi: 10.1038/ng.175

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

2008

Journal Article

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Loos, Ruth J. F., Evans, David M., Wellcome Trust Case Control Consortium, Brown, Matthew A. and Bradbury, Linda A. (2008). Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genetics, 40 (6), 768-775. doi: 10.1038/ng.140

Common variants near MC4R are associated with fat mass, weight and risk of obesity

2008

Journal Article

Genome-wide association analysis identifies 20 loci that influence adult height

Weedon, Michael N., Evans, David M., Wellcome Trust Case Control Consortium, Brown, Matthew A. and Bradbury, Linda A. (2008). Genome-wide association analysis identifies 20 loci that influence adult height. Nature Genetics, 40 (5), 575-583. doi: 10.1038/ng.121

Genome-wide association analysis identifies 20 loci that influence adult height

2008

Conference Publication

Genome-wide association study identifies klotho and other novel loci as contributors to BMD variation in postmenopausal women

Duncan, E. L., Rivadeneira, F., Sims, A., Dowling, A., Doan, T., Arp, P. P., Jhamai, M., Moorhouse, M., Evans, D., Eisman, J., Jones, G., Nicholson, G., Prince, R., Seeman, E., Wass, J. A. H., Hofman, A., Pols, H. A., Brown, M. A. and Uitterlinden, A. G. (2008). Genome-wide association study identifies klotho and other novel loci as contributors to BMD variation in postmenopausal women. 35th European Symposium on Calcified Tissues, Barcelona, Spain, 24-28 May 2008. New York, United States: Springer.

Genome-wide association study identifies klotho and other novel loci as contributors to BMD variation in postmenopausal women

2008

Journal Article

A genome-wide scan for Eysenckian personality dimensions in adolescent twin sibships: Psychoticism, Extraversion, Neuroticism, and Lie

Gillespie, Nathan A., Zhu, Gu, Evans, David M., Medland, Sarah E., Wright, Margie J. and Martin, Nick G. (2008). A genome-wide scan for Eysenckian personality dimensions in adolescent twin sibships: Psychoticism, Extraversion, Neuroticism, and Lie. Journal of Personality, 76 (6), 1415-1445. doi: 10.1111/j.1467-6494.2008.00527.x

A genome-wide scan for Eysenckian personality dimensions in adolescent twin sibships: Psychoticism, Extraversion, Neuroticism, and Lie

2008

Journal Article

To what extent do scans of non-synonymous SNPs complement denser genome-wide association studies?

Evans, David M., Barrett, Jeffrey C. and Cardon, Lon R. (2008). To what extent do scans of non-synonymous SNPs complement denser genome-wide association studies?. European Journal of Human Genetics, 16 (6), 718-723. doi: 10.1038/sj.ejhg.5202011

To what extent do scans of non-synonymous SNPs complement denser genome-wide association studies?

2008

Conference Publication

Diagnostic capacity of genetic tests in Ankylosing spondylitis can exceed MRI scanning

Evans, David, Reveille, John D., Weisman, Michael H., Stone, Millicent A., Ward, Michael M., Savage, Laurie, Zhou, Xiaodong, Wordsworth, B. Paul and Brown, Matthew A. (2008). Diagnostic capacity of genetic tests in Ankylosing spondylitis can exceed MRI scanning. 72nd Annual Scientific Meeting of the American-College-of-Rheumatology/43rd Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals, San Francisco Ca, Oct 24-29, 2008. HOBOKEN: WILEY-LISS.

Diagnostic capacity of genetic tests in Ankylosing spondylitis can exceed MRI scanning

2008

Conference Publication

Phased genome-wide association study identifies new gene affecting bone mineral density

Duncan, E. L., Addison, K., Brugmans, M., Irwin, D., Evans, D., Eisman, J., Jones, G., Nicholson, G., Prince, R., Seeman, E., Uitterlinden, A., Wark, J., Ralston, S. and Brown, M. A. (2008). Phased genome-wide association study identifies new gene affecting bone mineral density. American Society for Bone and Mineral Research (ASBMR) 30th Annual Meeting, Montreal,Canada, 12 - 16 September 2008. Malden, MA, United States: Wiley-Blackwell. doi: 10.1002/jbmr.5650231306

Phased genome-wide association study identifies new gene affecting bone mineral density

2007

Journal Article

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

Nejentsev, S., Howson, J. M. M., Walker, N. M., Szeszko, J., Field, S. F., Stevens, H. E., Reynolds, P., Hardy, M., King, E., Masters, J., Hulme, J., Maier, L. M., Smyth, D., Bailey, R., Cooper, J. D., Ribas, G., Campbell, R. D., The Wellcome Trust Case Control Consortium, Bradbury, Linda A., Brown, Matthew A. and Evans, David (2007). Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature, 450 (7171), 887-892. doi: 10.1038/nature06406

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

2007

Journal Article

Rheumatoid arthritis association at 6q23

Thompson, Wendy, Wellcome Trust Case Control Consortium, Brown, Matthew A., Bradbury, Linda A., et al. and Evans, David (2007). Rheumatoid arthritis association at 6q23. Nature Genetics, 39 (12), 1431-1433. doi: 10.1038/ng.2007.32

Rheumatoid arthritis association at 6q23

2007

Journal Article

Association scan of 14,000 nonsynonymous SNP's in four diseases identifies autoimmunity variants

Wellcome Trust Case control Consortium, The Australo-Anglo-American Spondylitis Consortium, Sims, A-M., Bradbury, L. A., Brown, M. A., Doan, T., Dowling, A. and Evans, D. (2007). Association scan of 14,000 nonsynonymous SNP's in four diseases identifies autoimmunity variants. Nature Genetics, 39 (11), 1329-1337. doi: 10.1038/ng.2007.17

Association scan of 14,000 nonsynonymous SNP's in four diseases identifies autoimmunity variants

2007

Journal Article

Genome-wide detection and characterization of positive selection in human populations

Sabeti P.C., Varilly P., Fry B., Lohmueller J., Hostetter E., Cotsapas C., Xie X., Byrne E.H., McCarroll S.A., Gaudet R., Schaffner S.F., Lander E.S., Frazer K.A., Ballinger D.G., Cox D.R., Hinds D.A., Stuve L.L., Gibbs R.A., Belmont J.W., Boudreau A., Hardenbol P., Leal S.M., Pasternak S., Wheeler D.A., Willis T.D., Yu F., Yang H., Zeng C., Gao Y. ... Stewart J. (2007). Genome-wide detection and characterization of positive selection in human populations. Nature, 449 (7164), 913-918. doi: 10.1038/nature06250

Genome-wide detection and characterization of positive selection in human populations

2007

Journal Article

A second generation human haplotype map of over 3.1 million SNPs

Frazer, K.A., Ballinger, D.G., Cox, D.R., Hinds, D.A., Stuve, L.L., Gibbs, R.A., Belmont, J.W., Boudreau, A., Hardenbol, P., Leal, S.M., Pasternak, S., Wheeler, D.A., Willis, T.D., Yu, F., Yang, H., Zeng, C., Gao, Y., Hu, H., Hu, W., Li, C., Lin, W., Liu, S., Pan, H., Tang, X., Wang, J., Wang, W., Yu, J., Zhang, B., Zhang, Q. ... Stewart, J. (2007). A second generation human haplotype map of over 3.1 million SNPs. Nature, 449 (7164), 851-861. doi: 10.1038/nature06258

A second generation human haplotype map of over 3.1 million SNPs

2007

Journal Article

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

The Wellcome Trust Case Control Consortium, Bradbury, L. A., Brown, M. A. and Evans, D. (2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447 (7145), 661-678. doi: 10.1038/nature05911

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

2007

Conference Publication

A Phase 1 Genomewide Association Study in Osteoporosis

Sims, A. M., Duncan, E. L., Dowling, A., Doan, T., Evans, D., Eisman, J., Jones, G., Nicholson, G., Prince, R., Seeman, E., Wass, J. and Brown, M. A. (2007). A Phase 1 Genomewide Association Study in Osteoporosis. GeneMappers 2007 Conference, Brisbane, Queensland, Australia, 29-31 August 2007.

A Phase 1 Genomewide Association Study in Osteoporosis

2007

Conference Publication

A phase 1 Genome-wide association study in Ostoeporosis

Sims, A. M., Duncan, E. L., Dowling, A., Doan, T., Evans, D., Eisman, J., Jones, G., Nicholson, G., Prince, R., Seeman, E., Wass, J. and Brown, M. A. (2007). A phase 1 Genome-wide association study in Ostoeporosis. 17th Annual Meeting of the Australian & New Zealand Bone & Mineral Society, Queenstown, New Zealand,, 9-12 September, 2007.

A phase 1 Genome-wide association study in Ostoeporosis

2007

Journal Article

Genomewide scans of red cell indices suggest linkage on chromosome 6q23

Iliadou, A., Evans, D. M., Zhu, G., Duffy, D. L., Frazer, I. H., Montgomery, G. W. and Martin, N. G. (2007). Genomewide scans of red cell indices suggest linkage on chromosome 6q23. Journal of Medical Genetics, 44 (1), 24-30. doi: 10.1136/jmg.2006.043521

Genomewide scans of red cell indices suggest linkage on chromosome 6q23

2007

Conference Publication

Il-23r is a major determinant of ankylosing spondylitis risk - The tasc study

Reveille, J. D., Zhou, X., Bradbury, L. A., Cardon, L. R., Davis, J. C., Deloukas, P., Evans, D. M., Keniry, A., McGinnis, R., Pointon, J., Ward, M. M., Weisman, M. H., Wordsworth, P. and Brown, M. A. (2007). Il-23r is a major determinant of ankylosing spondylitis risk - The tasc study. Annual European Congress of Rheumatology (EULAR 2007), Barcelona Spain, Jun 13-16, 2007. LONDON: B M J PUBLISHING GROUP.

Il-23r is a major determinant of ankylosing spondylitis risk - The tasc study

2006

Journal Article

Genome-wide association: a promising start to a long race

Evans, David M. and Cardon, Lon R. (2006). Genome-wide association: a promising start to a long race. Trends in Genetics, 22 (7), 350-354. doi: 10.1016/j.tig.2006.05.001

Genome-wide association: a promising start to a long race