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2016

Journal Article

CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer

Wu, Andy C., He, Yaowu, Broomfield, Amy, Paatan, Nicoll J., Harrington, Brittney S., Tseng, Hsu-Wen, Beaven, Elizabeth A., Kiernan, Deirdre M., Swindle, Peter, Clubb, Adrian B., Levesque, Jean-Pierre, Winkler, Ingrid G., Ling, Ming-Tat, Srinivasan, Bhuvana, Hooper, John D. and Pettit, Allison R. (2016). CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer. Journal of Pathology, 239 (2), 218-230. doi: 10.1002/path.4718

CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer

2016

Journal Article

Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer

Harrington, Brittney S., He, Yaowu, Davies, Claire M., Wallace, Sarah J., Adams, Mark N., Beaven, Elizabeth A., Roche, Deborah K., Kennedy, Catherine, Chetty, Naven P., Crandon, Alexander J., Flatley, Christopher, Oliveira, Niara B., Shannon, Catherine M., deFazio, Anna, Tinker, Anna V., Gilks, C. Blake, Gabrielli, Brian, Brennan, Donal J., Coward, Jermaine I., Armes, Jane E., Perrin, Lewis C. and Hooper, John D. (2016). Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer. British Journal of Cancer, 114 (4), 417-426. doi: 10.1038/bjc.2015.471

Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer

2016

Journal Article

New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways

He, Yaowu, Harrington, Brittney S. and Hooper, John D. (2016). New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways. Oncoscience, 3 (1), 5-8. doi: 10.18632/oncoscience.286

New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways

2016

Conference Publication

Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma

Ji, Pengxiang, Genovesi, Laura, He, Yaowu, Hooper, John and Wainwright, Brandon (2016). Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma. 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), Liverpool England, 12-15 June 2016. United States: Oxford University Press.

Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma

2016

Journal Article

Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance

He, Y., Wu, A. C., Harrington, B. S., Davies, C. M., Wallace, S. J., Adams, M. N., Palmer, J. S., Roche, D. K., Hollier, B. G., Westbrook, T. F., Hamidi, H., Konecny, G. E., Winterhoff, B., Chetty, N. P., Crandon, A. J., Oliveira, N. B., Shannon, C. M., Tinker, A. V., Gilks, C. B., Coward, J. I., Lumley, J. W., Perrin, L. C., Armes, J. E. and Hooper, J. D. (2016). Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance. Oncogene, 35 (4), 468-478. doi: 10.1038/onc.2015.101

Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance

2016

Conference Publication

MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target

Sheng, Yong H., He, Yaowu, Hasnain, Sumaira Z., Wang, Ran, Tong, Hui, Clarke, Daniel T., Lourie, Rohan, Oancea, Lulia, Wong, Kuanyau, Lumley, John W., Florin, Timothy H., Sutton, Philip, Hooper, John. D., Mcmillan, Nigel A. and Mcguckin, Michael A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, Los Angeles, 16-20 April 2016 . Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3564

MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target

2016

Conference Publication

The role of cancer stem cells in colorectal cancer metastasis

Kemp, M. C., Pummer, J., He, Y., Hooper, J., Reuter, B., Borgovan, T., Zhang, X., Sullivan, R., Maresh, G., Green, H., Del Valle, L., Margolin, D. and Li, L. (2016). The role of cancer stem cells in colorectal cancer metastasis. Southern Regional Meeting of the American Federation for Medical Research (AFMR), New Orleans, LA, United States, Feb 18-20, 2016. London, United Kingdom: BMJ Group. doi: 10.1136/jim-2015-000035.415

The role of cancer stem cells in colorectal cancer metastasis

2016

Journal Article

Potent small agonists of protease activated receptor 2

Yau, Mei-Kwan, Suen, Jacky Y., Xu, Weijun, Lim, Junxian, Liu, Ligong, Adams, Mark N., He, Yaowu, Hooper, John D., Reid, Robert C. and Fairlie, David P. (2016). Potent small agonists of protease activated receptor 2. ACS Medicinal Chemistry Letters, 7 (1), 105-110. doi: 10.1021/acsmedchemlett.5b00429

Potent small agonists of protease activated receptor 2

2015

Journal Article

Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2

Matsika, Admire, Srinivasan, Bhuvana, Day, Christopher, Mader, Sabina Ann, Kiernan, Deirdre Margaret, Broomfield, Amy, Fu, Jinlin, Hooper, John D., Kench, James G. and Samaratunga, Hemamali (2015). Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2. Pathology, 47 (7), 622-628. doi: 10.1097/PAT.0000000000000325

Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2

2015

Conference Publication

Potent small agonists of protease activated receptor 2

Yau, Mei Kwan, Suen, Jacky, Xu, Weijun, Lim, Junxian, Liu, Ligong, Adams, Mark, He, Yaowu, Hooper, John, Reid, Robert and Fairlie, David (2015). Potent small agonists of protease activated receptor 2. ACS Fall 2015, Boston, MA, United States, 16 - 20 August 2015. Washington, DC, United States: American Chemical Society.

Potent small agonists of protease activated receptor 2

2015

Journal Article

Tissue engineered humanized bone supports human hematopoiesis in vivo

Holzapfel, Boris M., Hutmacher, Dietmar W., Nowlan, Bianca, Barbier, Valerie, Thibaudeau, Laure, Theodoropoulos, Christina, Hooper, John D., Loessner, Daniela, Clements, Judith A., Russell, Pamela J., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2015). Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials, 61, 103-114. doi: 10.1016/j.biomaterials.2015.04.057

Tissue engineered humanized bone supports human hematopoiesis in vivo

2015

Journal Article

Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia

McDonald, Cameron J., Ostini, Lesa, Bennett, Nigel, Subramaniam, Nanthakumar, Hooper, John, Velasco, Gloria, Wallace, Daniel F. and Nathan Subramaniam, V. (2015). Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia. American Journal of Physiology - Cell Physiology, 308 (7), C539-C547. doi: 10.1152/ajpcell.00264.2014

Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia

2015

Journal Article

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

Wallace, Daniel F., Secondes, Eriza S., Rishi, Gautam, Ostini, Lesa, McDonald, Cameron J., Lane, Steven W., Vu, Therese, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2015). A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. British Journal of Haematology, 168 (6), 891-901. doi: 10.1111/bjh.13225

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

2015

Journal Article

Prevalence of osteoporosis in prostate cancer survivors II: a meta-analysis of men not on androgen deprivation therapy

Lassemillante, Annie-Claude M., Doi, Suhail A. R., Hooper, John D., Prins, John B. and Wright, Olivia R. L. (2015). Prevalence of osteoporosis in prostate cancer survivors II: a meta-analysis of men not on androgen deprivation therapy. Endocrine, 50 (2), 344-354. doi: 10.1007/s12020-015-0536-7

Prevalence of osteoporosis in prostate cancer survivors II: a meta-analysis of men not on androgen deprivation therapy

2015

Journal Article

EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface

Adams, M. N., Harrington, B. S., He, Y., Davies, C. M., Wallace, S. J., Chetty, N. P., Crandon, A. J., Oliveira, N. B., Shannon, C. M., Coward, J. I., Lumley, J. W., Perrin, L. C., Armes, J. E. and Hooper, J. D. (2015). EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface. Oncogene, 34 (11), 1375-1383. doi: 10.1038/onc.2014.88

EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface

2015

Conference Publication

EGF-induced recycling of the cancer promoting protein CDCP1

Adams, Mark N., Harrington, Brittney S., He, Yaowu, Davies, Claire M., Wallace, Sarah J., Chetty, Naven P., Crandon, Alexander J., Oliveira, Niara B., Shannon, Catherine M., Coward, Jermaine I., Lumley, John W., Perrin, Lewis C., Armes, Jane E. and Hooper, John D. (2015). EGF-induced recycling of the cancer promoting protein CDCP1. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

EGF-induced recycling of the cancer promoting protein CDCP1

2014

Journal Article

Activation of membrane-bound proteins and receptor systems: a link between tissue kallikrein and the KLK-related peptidases

Dong, Ying, Harrington, Brittney S., Adams, Mark N., Wortmann, Andreas, Stephenson, Sally-Anne, Lisle, Jessica, Herington, Adrian, Hooper, John D. and Clements, Judith A. (2014). Activation of membrane-bound proteins and receptor systems: a link between tissue kallikrein and the KLK-related peptidases. Biological Chemistry, 395 (9), 977-990. doi: 10.1515/hsz-2014-0147

Activation of membrane-bound proteins and receptor systems: a link between tissue kallikrein and the KLK-related peptidases

2014

Journal Article

Prevalence of osteoporosis in prostate cancer survivors: a meta-analysis

Lassemillante, Annie-Claude M., Doi, Suhail A. R, Hooper, John D., Prins, John B. and Wright, Olivia R. L. (2014). Prevalence of osteoporosis in prostate cancer survivors: a meta-analysis. Endocrine, 45 (3), 370-381. doi: 10.1007/s12020-013-0083-z

Prevalence of osteoporosis in prostate cancer survivors: a meta-analysis

2014

Journal Article

Expression profiles and functional associations of endogenous androgen receptor and caveolin-1 in prostate cancer cell lines

Bennett, Nigel C., Hooper, John D., Johnson, David W. and Gobe, Glenda C. (2014). Expression profiles and functional associations of endogenous androgen receptor and caveolin-1 in prostate cancer cell lines. Prostate, 74 (5), 478-487. doi: 10.1002/pros.22767

Expression profiles and functional associations of endogenous androgen receptor and caveolin-1 in prostate cancer cell lines

2014

Conference Publication

Targeting the cell surface protein Cdcp1 in a model of advanced ovarian cancer

Harrington, B., Davies, C. M., Wallace, S. J., He, Y., Armes, J. E., Perrin, L. C. and Hooper, J. D. (2014). Targeting the cell surface protein Cdcp1 in a model of advanced ovarian cancer. London, United Kingdom: B M J Group.

Targeting the cell surface protein Cdcp1 in a model of advanced ovarian cancer