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2020

Other Outputs

Substrate-biased activity-based probes identify the urokinase-plasminogen axis as a master regulator of metastatic signaling by orphan membrane receptor CDCP1

Kryza, Thomas, Khan, Tashbib, Lovell, Scott, Harrington, Brittney S., Yin, Julia, Porazinski, Sean, Pajic, Marina, Koistinen, Hannu, Rantala, Juha, Dreyer, Tobias, Magdolen, Viktor, Reuning, Ute, He, Yaowu, Tate, Edward and Hooper, John David (2020). Substrate-biased activity-based probes identify the urokinase-plasminogen axis as a master regulator of metastatic signaling by orphan membrane receptor CDCP1.

Substrate-biased activity-based probes identify the urokinase-plasminogen axis as a master regulator of metastatic signaling by orphan membrane receptor CDCP1

2020

Other Outputs

Binding proteins to CUB domain-containing protein (CDCP1)

Puttick, S., Kryza, T., Hooper, J. D., He, Y., Harrington, B., Quigley, J. and Deryugina, E. (2020). Binding proteins to CUB domain-containing protein (CDCP1). PCT/AU2020/051216.

Binding proteins to CUB domain-containing protein (CDCP1)

2020

Journal Article

PET imaging quantifying Ga-PSMA-11 uptake in metastatic colorectal cancer

Cuda, Tahleesa J., Riddell, Andrew D., Liu, Cheng, Whitehall, Vicki L., Borowsky, Jennifer, Wyld, David K., Burge, Matthew E., Ahern, Elizabeth, Griffin, Alison, Lyons, Nicholas J. R., Rose, Stephen E., Clark, David A., Stevenson, Andrew R. L., Hooper, John D., Puttick, Simon and Thomas, Paul A. (2020). PET imaging quantifying Ga-PSMA-11 uptake in metastatic colorectal cancer. The Journal of Nuclear Medicine, 61 (11), 1576-1579. doi: 10.2967/jnumed.119.233312

PET imaging quantifying Ga-PSMA-11 uptake in metastatic colorectal cancer

2020

Journal Article

Revisiting Glycogen in Cancer: A Conspicuous and Targetable Enabler of Malignant Transformation

Khan, Tashbib, Sullivan, Mitchell A., Gunter, Jennifer H., Kryza, Thomas, Lyons, Nicholas, He, Yaowu and Hooper, John D. (2020). Revisiting Glycogen in Cancer: A Conspicuous and Targetable Enabler of Malignant Transformation. Frontiers in Oncology, 10 592455, 592455. doi: 10.3389/fonc.2020.592455

Revisiting Glycogen in Cancer: A Conspicuous and Targetable Enabler of Malignant Transformation

2020

Journal Article

HBV induced hepatocellular carcinoma and related potential immunotherapy

Jia, Liyang, Gao, Yanan, He, Yaowu, Hooper, John D. and Yang, Pengyuan (2020). HBV induced hepatocellular carcinoma and related potential immunotherapy. Pharmacological Research, 159 104992, 104992. doi: 10.1016/j.phrs.2020.104992

HBV induced hepatocellular carcinoma and related potential immunotherapy

2020

Journal Article

miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer

Alharbi, Mona, Sharma, Shayna, Guanzon, Dominic, Lai, Andrew, Zuñiga, Felipe, Shiddiky, Muhammad J.A., Yamauchi, Yusuke, Salas-Burgos, Alexis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2020). miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 28 102207, 102207. doi: 10.1016/j.nano.2020.102207

miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer

2020

Journal Article

Disruption of glycogen utilization markedly improves the efficacy of carboplatin against preclinical models of clear cell ovarian carcinoma

Khan, Tashbib, He, Yaowu, Kryza, Thomas, Harrington, Brittney S., Gunter, Jennifer H., Sullivan, Mitchell A., Cuda, Tahleesa, Rogers, Rebecca, Davies, Claire M., Broomfield, Amy, Gough, Madeline, Wu, Andy C., McGann, Thomas, Weroha, S. John, Haluska, Paul, Forbes, Josephine M., Armes, Jane E., Barry, Sinead C., Coward, Jermaine I., Jagasia, Nisha, Chetty, Naven, Snell, Cameron E., Lourie, Rohan, Perrin, Lewis C. and Hooper, John D. (2020). Disruption of glycogen utilization markedly improves the efficacy of carboplatin against preclinical models of clear cell ovarian carcinoma. Cancers, 12 (4) 869, 869. doi: 10.3390/cancers12040869

Disruption of glycogen utilization markedly improves the efficacy of carboplatin against preclinical models of clear cell ovarian carcinoma

2020

Journal Article

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

Harrington, Brittney S., He, Yaowu, Khan, Tashbib, Puttick, Simon, Conroy, Paul J., Kryza, Thomas, Cuda, Tahleesa, Sokolowski, Kamil A., Tse, Brian W.C ., Robbins, Katherine K., Arachchige, Buddhika J., Stehbens, Samantha J., Pollock, Pamela M., Reed, Sarah, Weroha, S. John, Haluska, Paul, Salomon, Carlos, Lourie, Rohan, Perrin, Lewis C., Law, Ruby H. P., Whisstock, James C. and Hooper, John D. (2020). Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer. Theranostics, 10 (5), 2095-2114. doi: 10.7150/thno.30736

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

2020

Conference Publication

Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy

Sheng, Yong H., Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh Y., He, Yaowu, Wu, Andy, Hooper, John, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira Z., McGuckin, Michael, Florin, Timothy H. and Begun, Jakob (2020). Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy. DDW 2020, Online, 2-5 May 2020. Philadelphia, PA United States: Elsevier . doi: 10.1016/s0016-5085(20)30856-8

Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy

2020

Journal Article

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

Kryza, Thomas, Khan, Tashbib, Puttick, Simon, Li, Chao, Sokolowski, Kamil A., Tse, Brian W.C., Cuda, Tahleesa, Lyons, Nicholas, Gough, Madeline, Yin, Julia, Parkin, Ashleigh, Deryugina, Elena I., Quigley, James P., Law, Ruby H.P., Whisstock, James C., Riddell, Andrew D., Barbour, Andrew P., Wyld, David K., Thomas, Paul A., Rose, Stephen, Snell, Cameron E., Pajic, Marina, He, Yaowu and Hooper, John D. (2020). Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma. Theranostics, 10 (9), 4116-4133. doi: 10.7150/thno.43589

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

2019

Conference Publication

Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress

Andrews, Ariel, Kumar, Ramyashree Prasanna, Nazareth, Deborah, Ehmann, Anna, Hooper, John, McMillan, Nigel and Gabrielli, Brian (2019). Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress. AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, MA USA, 26-30 October 2019. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/1535-7163.TARG-19-A060

Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress

2019

Journal Article

The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer

Kryza, Thomas, Bock, Nathalie, Lovell, Scott, Rockstroh, Anja, Lehman, Melanie L., Lesner, Adam, Panchadsaram, Janaththani, Silva, Lakmali Munasinghage, Srinivasan, Srilakshmi, Snell, Cameron E., Williams, Elizabeth D., Fazli, Ladan, Gleave, Martin, Batra, Jyotsna, Nelson, Colleen, Tate, Edward W., Harris, Jonathan, Hooper, John D. and Clements, Judith A. (2019). The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer. Molecular Oncology, 14 (1) 1878-0261.12587, 105-128. doi: 10.1002/1878-0261.12587

The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer

2019

Conference Publication

"Theranostics" - radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer in preclinical cancer models

Cuda, T., Thomas, P., Rose, S., Puttick, S. and Hooper, J. (2019). "Theranostics" - radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer in preclinical cancer models. 32nd Annual Congress of the European-Association-of-Nuclear-Medicine (EANM), Barcelona, Spain, 12-16 October 2019. Heidelberg, Germany: Springer.

"Theranostics" - radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer in preclinical cancer models

2019

Journal Article

CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin

He, Yaowu, Davies, Claire M., Harrington, Brittney S., Hellmers, Linh, Sheng, Yonghua, Broomfield, Amy, McGann, Thomas, Bastick, Kate, Zhong, Laurie, Wu, Andy, Maresh, Grace, McChesney, Shannon, Yau Wong, Kuan, Adams, Mark N., Sullivan, Ryan C., Palmer, James S., Burke, Lez J., Ewing, Adam D., Zhang, Xin, Margolin, David, Li, Li, Lourie, Rohan, Matsika, Admire, Srinivasan, Bhuvana, McGuckin, Michael A., Lumley, John W. and Hooper, John D. (2019). CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin. Oncogene, 39 (1), 219-233. doi: 10.1038/s41388-019-0983-3

CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin

2019

Journal Article

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

2019

Journal Article

Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells

Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Palma, Carlos, Zuñiga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D and Salomon, Carlos (2019). Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells. Clinical Science, 133 (13), CS20190082-1419. doi: 10.1042/cs20190082

Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells

2019

Conference Publication

GALIUM-68-PSMA-617 AS A NOVEL PET-CT MARKER FOR DISEASE STRATIFYING METASTATIC COLORECTAL CANCER: A PROSPECTIVE PILOT STUDY

Cuda, T., Riddell, A., Thomas, P., Puttick, S. and Hooper, J. (2019). GALIUM-68-PSMA-617 AS A NOVEL PET-CT MARKER FOR DISEASE STRATIFYING METASTATIC COLORECTAL CANCER: A PROSPECTIVE PILOT STUDY. HOBOKEN: WILEY.

GALIUM-68-PSMA-617 AS A NOVEL PET-CT MARKER FOR DISEASE STRATIFYING METASTATIC COLORECTAL CANCER: A PROSPECTIVE PILOT STUDY

2019

Conference Publication

Ovarian cancer cell invasiveness regulates their exosomes which induces oncogenic potential and cancer progression in vivo

Alharbi, Mona G., Lai, Andrew, Zuniga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D. and Salomon, Carlos (2019). Ovarian cancer cell invasiveness regulates their exosomes which induces oncogenic potential and cancer progression in vivo. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, March 12-16, 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079

Ovarian cancer cell invasiveness regulates their exosomes which induces oncogenic potential and cancer progression in vivo

2019

Conference Publication

Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression

Sharma, Shayna, Lai, Andrew, Guanzon, Dominic, Morgan, Terry, Perrin, Lewis C., Hooper, John D. and Salomon, Carlos (2019). Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079

Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression

2019

Conference Publication

"Theranostics": radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer

Cuda, T., Hooper, J., Puttick, S., He, Y., Kryza, T. and Khan, T. (2019). "Theranostics": radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer. Australian and New Zealand Society of Nuclear Medicine (ANZSNM) 49th ASM, Adelaide, Australia, 26-28 April 2019. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

"Theranostics": radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer