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2025 Journal Article Antigen presentation potential is variable among human ovarian tumour and syngeneic murine models and dictates pre-clinical outcomes of immunotherapyAlim, Louisa, Adityan, Siddharth, Chen, Rui, Neilson, Trent, Coleborn, Elaina, Wilkinson, Andrew N., He, Yaowu, Irgam, Gowri, Bhavsar, Chintan, Lourie, Rohan, Rogers, Rebecca, Cabraal, Nimithri, Jagasia, Nisha, Chetty, Naven, Perrin, Lewis, Hooper, John D., Steptoe, Raymond and Wu, Sherry Y. (2025). Antigen presentation potential is variable among human ovarian tumour and syngeneic murine models and dictates pre-clinical outcomes of immunotherapy. Biomedicine & Pharmacotherapy, 187 118141, 118141. doi: 10.1016/j.biopha.2025.118141 |
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2025 Journal Article Receptor CDCP1 is a potential target for personalized imaging and treatment of poor outcome HER2+, triple negative and metastatic ER+/HER2- breast cancersGough, Madeline, Kwah, Kayden KX., Khan, Tashbib, Ghosh, Saikat, Sun, Biao, Lee, Catherine YJ., Sokolowski, Kamil A., Tse, Brian WC., Wickramasuriya, Lashith, Ferguson, Kaltin, Rogers, Rebecca, Goh, Justin B., Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J., Bray, Laura J., Liu, Cheng, Pyke, Christopher, Lim, Elgene, Snell, Cameron E., He, Yaowu, Hooper, John D. and Kryza, Thomas (2025). Receptor CDCP1 is a potential target for personalized imaging and treatment of poor outcome HER2+, triple negative and metastatic ER+/HER2- breast cancers. Clinical Cancer Research, 31 (8), 1504-1519. doi: 10.1158/1078-0432.ccr-24-2865 |
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2025 Journal Article Highlights of 2024. Broadening anti‐cancer immunotherapy modalities with antibody–drug conjugates: emerging insights from clinical studiesJose, Jiya, Hooper, John D and Souza‐Fonseca‐Guimaraes, Fernando (2025). Highlights of 2024. Broadening anti‐cancer immunotherapy modalities with antibody–drug conjugates: emerging insights from clinical studies. Immunology and Cell Biology. doi: 10.1111/imcb.70017 |
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2025 Journal Article Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survivalGodbole, Nihar, Lai, Andrew, Carrion, Flavio, Scholz-Romero, Katherin, Ravichandran, Akhilandeshwari, Kalita-de Croft, Priyakshi, McCart Reed, Amy E., Joshi, Vaibhavi, Lakhani, Sunil R., Masud, Mostafa Kamal, Yamauchi, Yusuke, Perrin, Lewis, Hooper, John, Bray, Laura, Guanzon, Dominic and Salomon, Carlos (2025). Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survival. Heliyon, 11 (4) e42188, 1-19. doi: 10.1016/j.heliyon.2025.e42188 |
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2025 Journal Article Development of a novel malignant colorectal polyp prognostic nomogramZammit, Andrew P., Aksoy, Yagiz Alp, Brown, Ian, Hooper, John D., Clark, David A., Fuchs, Talia L., Riddell, Andrew D. and Gill, Anthony J. (2025). Development of a novel malignant colorectal polyp prognostic nomogram. ANZ Journal of Surgery. doi: 10.1111/ans.19384 |
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2025 Journal Article Aurora B inhibition induces hyper-polyploidy and loss of long-term proliferative potential in RB and p53 defective cellsVora, Shivam, Chatterjee, Saptarshi, Andrew, Ariel, Kumar, Ramyashree Prasanna, Proctor, Martina, Zeng, Zhen, Bhatt, Rituparna, Nazareth, Deborah, Fernando, Madushan, Jones, Mathew J. K., He, Yaowu, Hooper, John D., McMillan, Nigel A. J., Urosevic, Jelena, Saeh, Jamal, Travers, Jon, Cimini, Daniela, Chen, Jing and Gabrielli, Brian (2025). Aurora B inhibition induces hyper-polyploidy and loss of long-term proliferative potential in RB and p53 defective cells. Cell Death & Disease, 16 (1) 7, 7-1. doi: 10.1038/s41419-024-07329-7 |
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2024 Journal Article Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibitionVora, Shivam, Andrew, Ariel, Kumar, Ramyashree Prasanna, Nazareth, Deborah, Bonfim-Melo, Alexis, Lim, Yoon, Ong, Xin Yee, Fernando, Madushan, He, Yaowu, Hooper, John D., McMillan, Nigel A. J., Urosevic, Jelena, Travers, Jon, Saeh, Jamal, Kumar, Sharad, Jones, Mathew J. K. and Gabrielli, Brian (2024). Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition. Cell Death & Disease, 15 (11) 810, 810. doi: 10.1038/s41419-024-07204-5 |
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2024 Journal Article Fibroblast activation protein (FAP) is overexpressed on both stromal and epithelial cells prior to pancreatic ductal adenocarcinoma: implications for early diagnosis on 68Ga-FAPI-PET/CTMcGahan, William, Gough, Madeline, Liu, Cheng, Hoyte, Sharon, Gill, Anthony J., Cavallucci, David, Australian Pancreatic Cancer Genome Initiative, Hooper, John D., Thomas, Paul A., Cooper, Caroline, O'Rourke, Thomas, Butler, Nick, Yeung, Shinn, Kryza, Thomas, Gulhane, Brook, Latter, Melissa J., Waddell, Nicola, Samra, Jaswinder S., Simpson, Fiona and Pajic, Marina (2024). Fibroblast activation protein (FAP) is overexpressed on both stromal and epithelial cells prior to pancreatic ductal adenocarcinoma: implications for early diagnosis on 68Ga-FAPI-PET/CT. Gastroenterology, 167 (6), 1217-1220. doi: 10.1053/j.gastro.2024.06.033 |
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2024 Journal Article Identification and characterization of TM4SF1+ tumor self-seeded cellsYang, Haotian, Wang, Haolu, He, Yaowu, Yang, Yang, Thompson, Erik W., Xia, Di, Burke, Leslie J., Cao, Lu, Hooper, John D., Roberts, Michael S., Crawford, Darrell H.G. and Liang, Xiaowen (2024). Identification and characterization of TM4SF1+ tumor self-seeded cells. Cell Reports, 43 (7) 114512, 1-24. doi: 10.1016/j.celrep.2024.114512 |
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2024 Conference Publication O47 FAP expression transforms early in the tumorigenesis of pancreatic ductal adenocarcinoma; and can be detected on FAPI-PET/CTMcGahan, William, Gough, Madeleine, Liu, Cheng, Cavallucci, David, Thomas, Paul and Hooper, John (2024). O47 FAP expression transforms early in the tumorigenesis of pancreatic ductal adenocarcinoma; and can be detected on FAPI-PET/CT. BSG LIVE'24, Birmingham, United Kingdom, 17-20 June 2024. London, United Kingdom: BMJ Group. doi: 10.1136/gutjnl-2024-bsg.47 |
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2024 Journal Article High throughput surface epitope immunoaffinity isolation of extracellular vesicles and downstream analysisKhanabdali, Ramin, Mandrekar, Michelle, Grygiel, Rick, Vo, Phuoc-an, Palma, Carlos, Nikseresht, Sara, Barton, Siena, Shojaee, Mozhgan, Bhuiyan, Sadman, Asari, Kartini, Belzer, Susan, Ansari, Khairul, Coward, Jermaine I., Perrin, Lewis, Hooper, John, Guanzon, Dominic, Lai, Andrew, Salomon, Carlos, Kershner, Kevin, Newton, Christine, Horejsh, Douglas and Rice, Gregory (2024). High throughput surface epitope immunoaffinity isolation of extracellular vesicles and downstream analysis. Biology Methods and Protocols, 9 (1) bpae032, bpae032. doi: 10.1093/biomethods/bpae032 |
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2024 Journal Article Estimation of risk posed by malignant polyps amongst colorectal surgeons in Australia and New ZealandZammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2024). Estimation of risk posed by malignant polyps amongst colorectal surgeons in Australia and New Zealand. Annals of Coloproctology, 40 (1), 114-120. doi: 10.3393/ac.2023.00178.0025 |
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2024 Conference Publication Changes in extracellular vesicle miRNAs from three-dimensional ovarian cancer cell models reflect physiological changes and cancer survivalGodbole, Nihar, Ravichandran, Akhilandeshwari, Guanzon, Dominic, Lai, Andrew, Carrion, Flavio, de Croft, Priyakshi Kalita, Perrin, Lewis, Hooper, John, Bray, Laura and Salomon, Carlos (2024). Changes in extracellular vesicle miRNAs from three-dimensional ovarian cancer cell models reflect physiological changes and cancer survival. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-3386 |
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2024 Journal Article Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cellsShah, Esha T., Molloy, Christopher, Gough, Madeline, Kryza, Thomas, Samuel, Selwin G., Tucker, Amos, Bhatia, Maneet, Ferguson, Genevieve, Heyman, Rebecca, Vora, Shivam, Monkman, James, Bolderson, Emma, Kulasinghe, Arutha, He, Yaowu, Gabrielli, Brian, Hooper, John D., Richard, Derek J., O’Byrne, Kenneth J. and Adams, Mark N. (2024). Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells. British Journal of Cancer, 130 (7), 1196-1205. doi: 10.1038/s41416-024-02584-z |
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2023 Journal Article UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancerHarrington, Brittney S., Kamdar, Rahul, Ning, Franklin, Korrapati, Soumya, Caminear, Michael W., Hernandez, Lidia F., Butcher, Donna, Edmondson, Elijah F., Traficante, Nadia, Hendley, Joy, Gough, Madeline, Rogers, Rebecca, Lourie, Rohan, Shetty, Jyoti, Tran, Bao, Elloumi, Fathi, Abdelmaksoud, Abdalla, Nag, Madhu Lal, Mazan-Mamczarz, Krystyna, House, Carrie D., Hooper, John D. and Annunziata, Christina M. (2023). UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer. Journal of Experimental and Clinical Cancer Research, 42 (1) 270, 270. doi: 10.1186/s13046-023-02820-z |
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2023 Journal Article Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancerGough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Schreiber, Veronika, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron E. (2023). Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer. Histopathology, 83 (4), 647-656. doi: 10.1111/his.15000 |
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2023 Journal Article MUC13 cell surface mucin limits Salmonella Typhimurium infection by protecting the mucosal epithelial barrierMcGuckin, Michael A., Davies, Julie M., Felgner, Pascal, Wong, Kuan Yau, Giri, Rabina, He, Yaowu, Moniruzzaman, Md., Kryza, Thomas, Sajiir, Haressh, Hooper, John D., Florin, Timothy H., Begun, Jakob, Oussalah, Abderrahim, Hasnain, Sumaira Z., Hensel, Michael and Sheng, Yong H. (2023). MUC13 cell surface mucin limits Salmonella Typhimurium infection by protecting the mucosal epithelial barrier. Cellular and Molecular Gastroenterology and Hepatology, 16 (6), 985-1009. doi: 10.1016/j.jcmgh.2023.08.011 |
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2023 Conference Publication Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancersKwah, Kayden, Gu, Weixi, Arachchige, Kasun S. A., He, Yaowu, Landsberg, Michael, Kobe, Bostjan and Hooper, John (2023). Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323084449 |
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2023 Conference Publication HER2 in situ hybridization testing in breast cancer: applying algorithm-assisted assessment to reduce interobserver variability in difficult casesGough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron Edward (2023). HER2 in situ hybridization testing in breast cancer: applying algorithm-assisted assessment to reduce interobserver variability in difficult cases. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.e13561 |
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2023 Conference Publication Development of a CUB domain-containing protein 1 (CDCP1)-targeting antibody-drug conjugate for triple-negative and metastatic breast cancerGough, Madeline, Kwah, Kayden, He, Yaowu, Snell, Cameron Edward, Hooper, John D. and Kryza, Thomas (2023). Development of a CUB domain-containing protein 1 (CDCP1)-targeting antibody-drug conjugate for triple-negative and metastatic breast cancer. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology (ASCO). doi: 10.1200/jco.2023.41.16_suppl.e15012 |
