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2008 Journal Article Mobilization of hematopoietic stem cells: state of the artLevesque, J-P. J. R. and Winkler, I.G. (2008). Mobilization of hematopoietic stem cells: state of the art. Current Opinion in Organ Transplantation, 13 (1), 53-58. doi: 10.1097/MOT.0b013e3282f42473 |
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2008 Journal Article The Use of Experimental Murine Models to Assess Novel Agents of Hematopoietic Stem and Progenitor Cell MobilizationHerbert, K.E., Levesque, J-P., Haylock, D.N. and Prince, M. (2008). The Use of Experimental Murine Models to Assess Novel Agents of Hematopoietic Stem and Progenitor Cell Mobilization. Biology of Blood and Marrow Transplantation, 14 (6), 603-621. doi: 10.1016/j.bbmt.2008.02.003 |
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2007 Journal Article Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cellsHerbert, Kirsten, Walkley, Carl R., Winkler, Ingrid G., Hendy, Jean, Olsen, Gemma Haines, Yuan, Yang-Dar, Chandraratna, Roshantha A., Prince, H. Miles, Lévesque, Jean-Pierre and Purton, Louise E. (2007). Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells. Cell Therapy and Islet Transplantation, 83 (4), 375-384. doi: 10.1097/01.tp.0000251376.75347.b4 |
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2007 Journal Article Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrowLevesque, J. P., Winkler, I. G., Hendy, J., Williams, B., Helwani, F., Barbier, V., Nowlan, B. and Nilsson, S. K. (2007). Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow. Stem Cells, 25 (8), 1954-1965. doi: 10.1634/stemcells.2006-0688 |
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2006 Journal Article Mechanisms of hematopoietic stem cell mobilization: When innate immunity assails the cells that make blood and boneWinkler, IG and Levesque, JP (2006). Mechanisms of hematopoietic stem cell mobilization: When innate immunity assails the cells that make blood and bone. Experimental Hematology, 34 (8), 996-1009. doi: 10.1016/j.exphem.2006.04.005 |
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2005 Journal Article Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilizationWinkler, IG, Hendy, J, Coughlin, P, Horvath, A and Levesque, JP (2005). Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization. Journal of Experimental Medicine, 201 (7), 1077-1088. doi: 10.1084/jem.20042299 |
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2005 Journal Article Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cellsEto, Tetsuya, Winkler, Ingrid, Purton, Louise E. and Levesque, Jean-Pierre (2005). Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells. Experimental Hematology, 33 (2), 232-242. doi: 10.1016/j.exphem.2004.10.018 |
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2005 Journal Article Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesisJorgensen-Tye, B, Levesque, JP, Royle, L, Doyonnas, R, Chan, JYH, Dwek, RA, Rudd, PM, Harvey, DJ, Simmons, PJ and Watt, SM (2005). Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis. Tissue Antigens, 65 (3), 220-239. doi: 10.1111/j.1399-0039.2005.00358.x |
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2005 Journal Article G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrowSemerad, CL, Christopher, MJ, Liu, FL, Short, B, Simmons, PJ, Winkler, I, Levesque, JP, Chappel, J, Ross, FP and Link, DC (2005). G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood, 106 (9), 3020-3027. doi: 10.1182/blood-2004-01-0272 |
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2004 Journal Article Characterization of hematopoietic progenitor mobilization in protease-deficient miceLevesque, JP, Liu, F, Simmons, PJ, Betsuyaku, T, Senior, RM, Pham, C and Link, DC (2004). Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood, 104 (1), 65-72. doi: 10.1182/blood-2003-05-1589 |
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2004 Journal Article Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1Winkler, IG, Snapp, KR, Simmons, PJ and Levesque, JP (2004). Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1. Blood, 103 (5), 1685-1692. doi: 10.1182/blood-2003-06-1921 |
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2003 Journal Article Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cellsLevesque, JP, Hendy, J, Winkler, IG, Takamatsu, Y and Simmons, PJ (2003). Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells. Experimental Hematology, 31 (2), 109-117. doi: 10.1016/S0301-472X(02)01028-7 |
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2003 Journal Article Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamideLevesque, JP, Hendy, J, Takamatsu, Y, Simmons, PJ and Bendall, LJ (2003). Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamide. Journal of Clinical Investigation, 111 (2), 187-196. doi: 10.1172/JCI200315994 |
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2002 Journal Article A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29)Levesque, JP, Takada, Y, Puzon-McLaughlin, W and Simmons, PJ (2002). A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29). Hybridoma and Hybridomics, 21 (4), 253-260. doi: 10.1089/153685902760213868 |
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2002 Journal Article Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environmentLevesque, JP, Hendy, J, Takamatsu, Y, Williams, B, Winkler, IG and Simmons, PJ (2002). Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment. Experimental Hematology, 30 (5), 440-449. doi: 10.1016/S0301-472X(02)00788-9 |
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2001 Journal Article Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factorLevesque, Jean-Pierre, Takamatsu, Yasushi, Nilsson, Yasushi, Haylock, Yasushi and Simmons, Yasushi (2001). Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor. Blood, 98 (5), 1289-1297. doi: 10.1182/blood.V98.5.1289 |
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2001 Journal Article Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cellsSimmons, PJ, Levesque, JP and Haylock, DN (2001). Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells. Hematopoietic Stem Cells 2000 Basic and Clinical Sciences, 938, 196-207. |
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2001 Journal Article Role of integrins and selectins in the development and regulation of the hematopoietic systemLévesque, J. P., Takamatsu, Y., Nilsson, S. K., Haylock, D. N. and Simmons, P. J. (2001). Role of integrins and selectins in the development and regulation of the hematopoietic system. Hematologie, 7 (2), 99-109. |
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2000 Journal Article Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrowLevesque, J. P., Takamatsu, Y., Nilsson, S. K., Haylock, D. N. and Simmons, P. J. (2000). Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrow. Blood, 96 (11 PART I). |
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2000 Journal Article CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptorDoyonnas, R, Chan, JYH, Butler, LH, Rappold, I, Lee-Prudhoe, JE, Zannettino, ACW, Simmons, PJ, Buhring, HJ, Levesque, JP and Watt, SM (2000). CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor. Journal of Immunology, 165 (2), 840-851. doi: 10.4049/jimmunol.165.2.840 |
