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2020

Journal Article

Role of ion-phospholipid interactions in zwitterionic phospholipid bilayer ion permeation

Deplazes, Evelyne, Tafalla, Beatriu Domingo, Cranfield, Charles G. and Garcia, Alvaro (2020). Role of ion-phospholipid interactions in zwitterionic phospholipid bilayer ion permeation. The Journal of Physical Chemistry Letters, 11 (15), 6353-6358. doi: 10.1021/acs.jpclett.0c01479

Role of ion-phospholipid interactions in zwitterionic phospholipid bilayer ion permeation

2020

Journal Article

Label-free, real-time phospholipase-A isoform assay

Garcia, Alvaro, Deplazes, Evelyne, Aili, Samira, Padula, Matthew P., Touchard, Axel, Murphy, Christopher, Lankage, Upeksha Mirissa, Nicholson, Graham M., Cornell, Bruce and Cranfield, Charles G. (2020). Label-free, real-time phospholipase-A isoform assay. ACS Biomaterials Science & Engineering, 6 (8), 4714-4721. doi: 10.1021/acsbiomaterials.0c00632

Label-free, real-time phospholipase-A isoform assay

2020

Journal Article

Molecular dynamics simulation of small molecules interacting with biological membranes

Martinotti, Carlo, Ruiz-Perez, Lanie, Deplazes, Evelyne and Mancera, Ricardo L. (2020). Molecular dynamics simulation of small molecules interacting with biological membranes. ChemPhysChem: a European journal of chemical physics and physical chemistry, 21 (14), 1486-1514. doi: 10.1002/cphc.202000219

Molecular dynamics simulation of small molecules interacting with biological membranes

2020

Journal Article

Revisiting the interaction of melittin with phospholipid bilayers: the effects of concentration and ionic strength

Sabapathy, Thiru, Deplazes, Evelyne and Mancera, Ricardo L. (2020). Revisiting the interaction of melittin with phospholipid bilayers: the effects of concentration and ionic strength. International Journal of Molecular Sciences, 21 (3) 746, 746. doi: 10.3390/ijms21030746

Revisiting the interaction of melittin with phospholipid bilayers: the effects of concentration and ionic strength

2020

Journal Article

Effect of H3O+ on the structure and dynamics of water at the interface with phospholipid bilayers

Deplazes, Evelyne, Sarrami, Farzaneh and Poger, David (2020). Effect of H3O+ on the structure and dynamics of water at the interface with phospholipid bilayers. The Journal of Physical Chemistry B, 124 (8) acs.jpcb.9b10169, 1361-1373. doi: 10.1021/acs.jpcb.9b10169

Effect of H3O+ on the structure and dynamics of water at the interface with phospholipid bilayers

2019

Journal Article

The unusual conformation of cross‐strand disulfide bonds is critical to the stability of β‐hairpin peptides

Deplazes, Evelyne, Chin, Yanni K.‐Y., King, Glenn F. and Mancera, Ricardo L. (2019). The unusual conformation of cross‐strand disulfide bonds is critical to the stability of β‐hairpin peptides. Proteins, 88 (3) prot.25828, 485-502. doi: 10.1002/prot.25828

The unusual conformation of cross‐strand disulfide bonds is critical to the stability of β‐hairpin peptides

2019

Journal Article

Competing for the same space: protons and alkali ions at the interface of phospholipid bilayers

Deplazes, Evelyne, White, Jacqueline, Murphy, Christopher, Cranfield, Charles G. and Garcia, Alvaro (2019). Competing for the same space: protons and alkali ions at the interface of phospholipid bilayers. Biophysical Reviews, 11 (3), 483-490. doi: 10.1007/s12551-019-00541-2

Competing for the same space: protons and alkali ions at the interface of phospholipid bilayers

2018

Journal Article

The effect of H3O+ on the membrane morphology and hydrogen bonding of a phospholipid bilayer

Deplazes, Evelyne, Poger, David, Cornell, Bruce and Cranfield, Charles G. (2018). The effect of H3O+ on the membrane morphology and hydrogen bonding of a phospholipid bilayer. Biophysical Reviews, 10 (5), 1371-1376. doi: 10.1007/s12551-018-0454-z

The effect of H3O+ on the membrane morphology and hydrogen bonding of a phospholipid bilayer

2018

Journal Article

Characterisation of the structure and oligomerisation of Islet Amyloid Polypeptides (IAPP): a review of molecular dynamics simulation studies

Moore, Sandra J., Sonar, Krushna, Bharadwaj, Prashant, Deplazes, Evelyne and Mancera, Ricardo L. (2018). Characterisation of the structure and oligomerisation of Islet Amyloid Polypeptides (IAPP): a review of molecular dynamics simulation studies. Molecules, 23 (9) 2142, 1-37. doi: 10.3390/molecules23092142

Characterisation of the structure and oligomerisation of Islet Amyloid Polypeptides (IAPP): a review of molecular dynamics simulation studies

2018

Journal Article

The Biological and Biophysical Properties of the Spider Peptide Gomesin

Tanner, John D., Deplazes, Evelyne and Mancera, Ricardo L. (2018). The Biological and Biophysical Properties of the Spider Peptide Gomesin. Molecules, 23 (7) 1733, 1-19. doi: 10.3390/molecules23071733

The Biological and Biophysical Properties of the Spider Peptide Gomesin

2018

Journal Article

Molecular simulations of venom peptide-membrane interactions: progress and challenges

Deplazes, Evelyne (2018). Molecular simulations of venom peptide-membrane interactions: progress and challenges. Peptide Science, 110 (3) e24060, e24060. doi: 10.1002/pep2.24060

Molecular simulations of venom peptide-membrane interactions: progress and challenges

2018

Journal Article

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

Fernandez-Rojo, Manuel A., Deplazes, Evelyne, Pineda, Sandy S., Brust, Andreas, Marth, Tano, Wilhelm, Patrick, Martel, Nick, Ramm, Grant A., Mancera, Ricardo L., Alewood, Paul F., Woods, Gregory M., Belov, Katherine, Miles, John J., King, Glenn F. and Ikonomopoulou, Maria P. (2018). Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4 (1) 19, 19. doi: 10.1038/s41420-018-0030-0

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

2018

Conference Publication

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

Schroeder, Christina, Agwa, Akello, Mueller, Alexander, Chow, Chun Yuen, Peigneur, Steve, Lawrence, Nicole, Deplazes, Evelyne, Mark, Alan, Craik, David, Tytgat, Jan, King, Glenn, Vetter, Irina and Henriques, Sonia Troeira (2018). The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

2017

Journal Article

The effect of hydronium ions on the structure of phospholipid membranes

Deplazes, Evelyne, Poger, David, Cornell, Bruce and Cranfield, Charles G. (2017). The effect of hydronium ions on the structure of phospholipid membranes. Physical Chemistry Chemical Physics, 20 (1), 357-366. doi: 10.1039/c7cp06776c

The effect of hydronium ions on the structure of phospholipid membranes

2017

Journal Article

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017)

Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sonia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017). Biochimica Et Biophysica Acta-Biomembranes, 1859 (11), 2277-2277. doi: 10.1016/j.bbamem.2017.08.008

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017)

2017

Journal Article

A potential new, stable state of the E-cadherin strand-swapped dimer in solution

Schumann-Gillett, Alexandra, Mark, Alan E., Deplazes, Evelyne and O'Mara, Megan L. (2017). A potential new, stable state of the E-cadherin strand-swapped dimer in solution. European Biophysics Journal, 47 (1), 59-67. doi: 10.1007/s00249-017-1229-3

A potential new, stable state of the E-cadherin strand-swapped dimer in solution

2017

Journal Article

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7

Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sónia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochimica et Biophysica Acta. Biomembranes, 1859 (5), 835-844. doi: 10.1016/j.bbamem.2017.01.020

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7

2017

Journal Article

Molecular simulations of disulfide-rich venom peptides with ion channels and membranes

Deplazes, Evelyne (2017). Molecular simulations of disulfide-rich venom peptides with ion channels and membranes. Molecules, 22 (3) 362, 362. doi: 10.3390/molecules22030362

Molecular simulations of disulfide-rich venom peptides with ion channels and membranes

2017

Conference Publication

The importance of peptide-membrane interactions in toxin inhibitions of sodium channels

Schroeder, Christina I., Deplazes, Evelyn, Lawrence, Nicole, Agwa, Akello and Henriques, Sonia T. (2017). The importance of peptide-membrane interactions in toxin inhibitions of sodium channels. 58th Annual Meeting of the Biophysical Society, San Francisco, United States, 15-19 February 2014. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2016.11.1247

The importance of peptide-membrane interactions in toxin inhibitions of sodium channels

2016

Journal Article

Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7

Troeira Henriques, Sonia, Deplazes, Evelyne, Lawrence, Nicole, Cheneval, Olivier, Chaousis, Stephanie, Inserra, Marco, Thongyoo, Panumart, King, Glenn F., Mark, Alan E., Vetter, Irina, Craik, David J. and Schroeder, Christina Ingrid (2016). Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7. The Journal of Biological Chemistry, 291 (33), 17049-17065. doi: 10.1074/jbc.M116.729095

Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7