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2017 Journal Article Platform technologies for modern vaccine manufacturingCharlton Hume, Hayley K. and Lua, Linda H. L. (2017). Platform technologies for modern vaccine manufacturing. Vaccine, 35 (35), 4480-4485. doi: 10.1016/j.vaccine.2017.02.069 |
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2017 Journal Article Small-molecule inhibitors of the SOX18 transcription factorFontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A. B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes and Francois, Mathias (2017). Small-molecule inhibitors of the SOX18 transcription factor. Chemistry Chemical Biology, 24 (3), 346-359. doi: 10.1016/j.chembiol.2017.01.003 |
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2017 Journal Article Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?Razaghi, Ali, Tan, Emilyn, Lua, Linda H. L., Owens, Leigh, Karthikeyan, O. P. and Heimann, Kirsten (2017). Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?. Biologicals, 45, 52-60. doi: 10.1016/j.biologicals.2016.09.015 |
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2016 Journal Article Modular virus-like particles for sublingual vaccination against group A streptococcusSeth, Arjun, Kong, Il Gyu, Lee, Su-Hyun, Yang, Jin-Young, Lee, Yong-Soo, Kim, Yeji, Wibowo, Nani, Middelberg, Anton P.J., Lua, Linda H.L. and Kweon, Mi-Na (2016). Modular virus-like particles for sublingual vaccination against group A streptococcus. Vaccine, 34 (51), 6472-6480. doi: 10.1016/j.vaccine.2016.11.008 |
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2016 Journal Article Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccinationWaneesorn, Jarurin, Wibowo, Nani, Bingham, John, Middelberg, Anton P. J. and Lua, Linda H.L. (2016). Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccination. Vaccine, 36 (22), 3064-3071. doi: 10.1016/j.vaccine.2016.11.058 |
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2016 Journal Article Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigenTekewe, Alemu, Fan, Yuanyuan, Tan, Emilyn, Middelberg, Anton P. J. and Lua, Linda H. L. (2016). Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen. Biotechnology and Bioengineering, 114 (2), 397-406. doi: 10.1002/bit.26068 |
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2016 Journal Article Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particleTekewe, Alemu, Connors, Natalie K., Middelberg, Anton P. J. and Lua, Linda H. L. (2016). Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle. Protein Science, 25 (8), 1507-1516. doi: 10.1002/pro.2953 |
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2015 Journal Article Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particleLua, Linda H.L., Fan, Yuanyuan, Chang, Cindy, Connors, Natalie K. and Middelberg, Anton P.J. (2015). Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particle. Vaccine, 33 (44), 5937-5944. doi: 10.1016/j.vaccine.2015.09.017 |
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2015 Journal Article VaccineWibowo, Nani, Lua, Linda Hwee-Lin, Jungbauer, Alois and Ma, Guanghui (2015). Vaccine. Vaccine Engineering, 33 (44), 5889-5889. doi: 10.1016/j.vaccine.2015.10.002 |
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2015 Journal Article Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenzaWibowo, Nani, Wu, Yang, Fan, Yuanyuan, Meers, Joanne, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza. Vaccine, 33 (44), 5960-5965. doi: 10.1016/j.vaccine.2015.08.100 |
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2015 Journal Article Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopesAbidin, R.S., Lua, L.H.L., Middelberg, A.P.J. and Sainsbury, F. (2015). Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes. Protein Science, 24 (11), 1820-1828. doi: 10.1002/pro.2775 |
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2015 Journal Article Biomolecular engineering of virus-like particles aided by computational chemistry methodsZhang, Lin, Lua, Linda H. L., Middelberg, Anton P. J., Sun, Yan and Connors, Natalie K. (2015). Biomolecular engineering of virus-like particles aided by computational chemistry methods. Chemical Society Reviews, 44 (23), 8608-8618. doi: 10.1039/c5cs00526d |
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2015 Journal Article A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidatesTekewe, Alemu, Connors, Natalie K., Sainsbury, Frank, Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidates. Biochemical Engineering Journal, 100, 50-58. doi: 10.1016/j.bej.2015.04.004 |
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2015 Journal Article Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent MannerSeth, Arjun, Ritchie, Fiona K., Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent Manner. PLoS One, 10 (3) 0117203, e0117203-e0117203. doi: 10.1371/journal.pone.0117203 |
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2015 Journal Article Development of picornavirus-like particle vaccinesSomasundaram, Balaji and Lua, Linda H. L. (2015). Development of picornavirus-like particle vaccines. Pharmaceutical Bioprocessing, 3 (1), 45-49. doi: 10.4155/pbp.14.39 |
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2015 Journal Article Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect CellsSomasundaram, Balaji, Chang, Cindy, Fan, Yuan Y., Lim, Pei-Yin, Cardosa, Jane and Lua, Linda (2015). Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect Cells. Methods, 95, 38-45. doi: 10.1016/j.ymeth.2015.09.023 |
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2014 Journal Article The economics of virus-like particle and capsomere vaccinesChuan, Yap P., Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2014). The economics of virus-like particle and capsomere vaccines. Biochemical Engineering Journal, 90, 255-263. doi: 10.1016/j.bej.2014.06.005 |
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2014 Journal Article Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulationsZhang, Lin, Tang, Ronghong, Bai, Shu, Connors, Natalie K., Lua, Linda H. L., Chuan, Yap P., Middelberg, Anton P. J. and Sun, Yan (2014). Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations. PLoS One, 9 (9) e107313, e107313.1-e107313.12. doi: 10.1371/journal.pone.0107313 |
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2014 Journal Article Co-administration of non-carrier nanoparticles boosts antigen immune response without requiring protein conjugationWibowo, Nani, Chuan, Yap P., Seth, Arjun, Cordoba, Yoann, Lua, Linda H. L. and Middelberg, Anton P. J. (2014). Co-administration of non-carrier nanoparticles boosts antigen immune response without requiring protein conjugation. Vaccine, 32 (29), 3664-3669. doi: 10.1016/j.vaccine.2014.04.043 |
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2014 Journal Article Protective efficacy of a bacterially produced modular capsomere presenting M2e from influenza: Extending the potential of broadly cross-protecting epitopesWibowo, Nani, Hughes, Fiona K., Fairmaid, Emily J., Lua, Linda H. L., Brown, Lorena E. and Middelberg, Anton P. J. (2014). Protective efficacy of a bacterially produced modular capsomere presenting M2e from influenza: Extending the potential of broadly cross-protecting epitopes. Vaccine, 32 (29), 3651-3655. doi: 10.1016/j.vaccine.2014.04.062 |
