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2024

Journal Article

Effective Parallel Evaluation of Molecular Design, Expression and Bioactivity of Novel Recombinant Butyrylcholinesterase Medical Countermeasures

Allard, Joanne L., Aguirre, Miguel, Gupta, Ruchi, Chua, Sheena.M.H., Shields, Katherine A. and Lua, Linda.H.L. (2024). Effective Parallel Evaluation of Molecular Design, Expression and Bioactivity of Novel Recombinant Butyrylcholinesterase Medical Countermeasures. Chemico-Biological Interactions, 403 111219, 111219. doi: 10.1016/j.cbi.2024.111219

Effective Parallel Evaluation of Molecular Design, Expression and Bioactivity of Novel Recombinant Butyrylcholinesterase Medical Countermeasures

2022

Journal Article

Design and optimization of membrane chromatography for monoclonal antibody charge variant separation

Nadar, Sathish, Somasundaram, Balaji, Charry, Marcela, Billakanti, Jagan, Shave, Evan, Baker, Kym and Lua, Linda H. L. (2022). Design and optimization of membrane chromatography for monoclonal antibody charge variant separation. Biotechnology Progress, 38 (6) e3288, 1-15. doi: 10.1002/btpr.3288

Design and optimization of membrane chromatography for monoclonal antibody charge variant separation

2022

Journal Article

Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning

Allard, Joanne L., Shields, Katherine A., Munro, Trent P. and Lua, Linda H.L. (2022). Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning. Chemico-Biological Interactions, 363 109996, 109996. doi: 10.1016/j.cbi.2022.109996

Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning

2022

Book Chapter

Protein expression optimization strategies in E. coli: a tailored approach in strain selection and parallelizing expression conditions

Tang, Shyn Ric, Somasundaram, Balaji and Lua, Linda H. L. (2022). Protein expression optimization strategies in E. coli: a tailored approach in strain selection and parallelizing expression conditions. Insoluble proteins: methods and protocols. (pp. 93-111) edited by Elena Garcia Fruitos and Anna Arı´s Giralt. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1859-2_5

Protein expression optimization strategies in E. coli: a tailored approach in strain selection and parallelizing expression conditions

2021

Journal Article

Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases

Yap, Kuok, Du, Junqiao, Rehm, Fabian B. H., Tang, Shyn Ric, Zhou, Yan, Xie, Jing, Wang, Conan K., de Veer, Simon J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2021). Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases. Nature Protocols, 16 (3), 1-23. doi: 10.1038/s41596-020-00483-0

Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases

2021

Journal Article

Ambient temperature stable, scalable COVID-19 polymer particle vaccines induce protective immunity

Chen, Shuxiong, Evert, Benjamin, Adeniyi, Adetayo, Salla-Martret, Mercè, Lua, Linda H.-L., Ozberk, Victoria, Pandey, Manisha, Good, Michael F., Suhrbier, Andreas, Halfmann, Peter, Kawaoka, Yoshihiro and Rehm, Bernd H. A. (2021). Ambient temperature stable, scalable COVID-19 polymer particle vaccines induce protective immunity. Advanced Healthcare Materials, 11 (3) 2102089, 2102089. doi: 10.1002/adhm.202102089

Ambient temperature stable, scalable COVID-19 polymer particle vaccines induce protective immunity

2021

Journal Article

Current status and future challenges in transitioning to continuous bioprocessing of virus-like particles

Mittal, Manya, Banerjee, Manidipa, Lua, Linda H. L. and Rathore, Anurag S. (2021). Current status and future challenges in transitioning to continuous bioprocessing of virus-like particles. Journal of Chemical Technology and Biotechnology, 97 (9) jctb.6821, 2376-2385. doi: 10.1002/jctb.6821

Current status and future challenges in transitioning to continuous bioprocessing of virus-like particles

2020

Journal Article

Intensified downstream processing of monoclonal antibodies using membrane technology

Nadar, Sathish, Shooter, Gary, Somasundaram, Balaji, Shave, Evan, Baker, Kym and Lua, Linda H.L. (2020). Intensified downstream processing of monoclonal antibodies using membrane technology. Biotechnology Journal, 16 (3) 2000309, 1-11. doi: 10.1002/biot.202000309

Intensified downstream processing of monoclonal antibodies using membrane technology

2020

Journal Article

To our readers: Important notice

Poland, Gregory A., van Dijk, Nicolette, Altmann, Danny, Borrow, Ray, Hung, Ivan, Ishii, Ken, Jacobsen, Steve, Krammer, Florian, Larson, Heidi, Lua, Linda, Middelberg, Anton, Nelson, Jennifer, Neuzil, Kathy, Nohynek, Hanna, Reingold, Art, van den Hurk, Sylvia, Kennedy, Rick B. and Sadarangani, Sapna (2020). To our readers: Important notice. Vaccine, 38 (35). doi: 10.1016/j.vaccine.2020.07.001

To our readers: Important notice

2020

Journal Article

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

Yap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

2020

Journal Article

Protein expression in the baculovirus-insect cell expression system

Adeniyi, Adetayo A. and Lua, Linda Hwee-Lin (2020). Protein expression in the baculovirus-insect cell expression system. Methods in Molecular Biology, 2073, 17-37. doi: 10.1007/978-1-4939-9869-2_2

Protein expression in the baculovirus-insect cell expression system

2019

Journal Article

Vaccine Technology VII: beyond the “decade of vaccines”

Kamen, Amine A., Lua, Linda H. L. and Mukhopadhyay, Tarit K. (2019). Vaccine Technology VII: beyond the “decade of vaccines”. Vaccine, 37 (47), 6931-6932. doi: 10.1016/j.vaccine.2019.09.083

Vaccine Technology VII: beyond the “decade of vaccines”

2019

Journal Article

Evaluation of process simulation as a decisional tool for biopharmaceutical contract development and manufacturing organizations

Pleitt, Kristina, Somasundaram, Balaji, Johnson, Bradley, Shave, Evan and Lua, Linda H.L. (2019). Evaluation of process simulation as a decisional tool for biopharmaceutical contract development and manufacturing organizations. Biochemical Engineering Journal, 150 107252, 107252. doi: 10.1016/j.bej.2019.107252

Evaluation of process simulation as a decisional tool for biopharmaceutical contract development and manufacturing organizations

2019

Journal Article

Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses

Pattinson, David J., Apte, Simon H., Wibowo, Nani, Chuan, Yap P., Rivera-Hernandez, Tania, Groves, Penny L., Lua, Linda H., Middelberg, Anton P. J. and Doolan, Denise L. (2019). Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses. Frontiers in Cellular and Infection Microbiology, 9 (JUN) 215, 215. doi: 10.3389/fcimb.2019.00215

Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses

2019

Journal Article

Synthetic biology for bioengineering virus-like particle vaccines

Charlton Hume, Hayley K., Vidigal, João, Carrondo, Manuel J. T., Middelberg, Anton P. J., Roldão, António and Lua, Linda H. L. (2019). Synthetic biology for bioengineering virus-like particle vaccines. Biotechnology and Bioengineering, 116 (4), 919-935. doi: 10.1002/bit.26890

Synthetic biology for bioengineering virus-like particle vaccines

2018

Journal Article

Progression of continuous downstream processing of monoclonal antibodies: current trends and challenges

Somasundaram, Balaji, Pleitt, Kristina, Shave, Evan, Baker, Kym and Lua, Linda H. L. (2018). Progression of continuous downstream processing of monoclonal antibodies: current trends and challenges. Biotechnology and Bioengineering, 115 (12), 2893-2907. doi: 10.1002/bit.26812

Progression of continuous downstream processing of monoclonal antibodies: current trends and challenges

2018

Journal Article

Antibody-binding, antifouling surface coatings based on recombinant expression of zwitterionic EK peptides

Walker, Julia A., Robinson, Kye J., Munro, Christopher, Gengenbach, Thomas, Muller, David A., Young, Paul R., Lua, Linda H. L. and Corrie, Simon R. (2018). Antibody-binding, antifouling surface coatings based on recombinant expression of zwitterionic EK peptides. Langmuir, 35 (5) acs.langmuir.8b00810, 1266-1272. doi: 10.1021/acs.langmuir.8b00810

Antibody-binding, antifouling surface coatings based on recombinant expression of zwitterionic EK peptides

2018

Journal Article

Vaccine Technology VI: innovative and integrated approaches in vaccine development

Palomares, Laura A., Mukhopadhyay, Tarit K., Genzel, Yvonne, Lua, Linda H.L. and Cox, Manon M.J. (2018). Vaccine Technology VI: innovative and integrated approaches in vaccine development. Vaccine, 36 (22), 3061-3063. doi: 10.1016/j.vaccine.2018.03.077

Vaccine Technology VI: innovative and integrated approaches in vaccine development

2018

Journal Article

Baculovirus-driven protein expression in insect cells: a benchmarking study

Stolt-Bergner, Peggy, Benda, Christian, Bergbrede, Tim, Besir, Hüseyin, Celie, Patrick H. N., Chang, Cindy, Drechsel, David, Fischer, Ariane, Geerlof, Arie, Giabbai, Barbara, van den Heuvel, Joop, Huber, Georg, Knecht, Wolfgang, Lehner, Anita, Lemaitre, Regis, Nordén, Kristina, Pardee, Gwynn, Racke, Ines, Remans, Kim, Sander, Astrid, Scholz, Judith, Stadnik, Magda, Storici, Paola, Weinbruch, Daniel, Zaror, Isabel, Lua, Linda H. L. and Suppmann, Sabine (2018). Baculovirus-driven protein expression in insect cells: a benchmarking study. Journal of Structural Biology, 203 (2), 71-80. doi: 10.1016/j.jsb.2018.03.004

Baculovirus-driven protein expression in insect cells: a benchmarking study

2017

Journal Article

Preface: Biosecurity

Lua, Linda H. L. and Fooks, Anthony R. (2017). Preface: Biosecurity. Vaccine, 35 (44), 5947-5948. doi: 10.1016/j.vaccine.2017.08.077

Preface: Biosecurity