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2017

Journal Article

Evaluation of three adjuvants with respect to both adverse effects and the efficacy of antibody production to the Bm86 protein

Petermann, Julie, Bonnefond, Romain, Mermoud, Isabelle, Rantoen, Dewi, Meynard, Laure, Munro, Christopher, Lua, Linda H. L. and Hue, Thomas (2017). Evaluation of three adjuvants with respect to both adverse effects and the efficacy of antibody production to the Bm86 protein. Experimental and Applied Acarology, 72 (3), 303-315. doi: 10.1007/s10493-017-0156-4

Evaluation of three adjuvants with respect to both adverse effects and the efficacy of antibody production to the Bm86 protein

2017

Journal Article

Platform technologies for modern vaccine manufacturing

Charlton Hume, Hayley K. and Lua, Linda H. L. (2017). Platform technologies for modern vaccine manufacturing. Vaccine, 35 (35), 4480-4485. doi: 10.1016/j.vaccine.2017.02.069

Platform technologies for modern vaccine manufacturing

2017

Journal Article

Small-molecule inhibitors of the SOX18 transcription factor

Fontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A. B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes and Francois, Mathias (2017). Small-molecule inhibitors of the SOX18 transcription factor. Chemistry Chemical Biology, 24 (3), 346-359. doi: 10.1016/j.chembiol.2017.01.003

Small-molecule inhibitors of the SOX18 transcription factor

2017

Journal Article

Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?

Razaghi, Ali, Tan, Emilyn, Lua, Linda H. L., Owens, Leigh, Karthikeyan, O. P. and Heimann, Kirsten (2017). Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?. Biologicals, 45, 52-60. doi: 10.1016/j.biologicals.2016.09.015

Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?

2016

Journal Article

Modular virus-like particles for sublingual vaccination against group A streptococcus

Seth, Arjun, Kong, Il Gyu, Lee, Su-Hyun, Yang, Jin-Young, Lee, Yong-Soo, Kim, Yeji, Wibowo, Nani, Middelberg, Anton P.J., Lua, Linda H.L. and Kweon, Mi-Na (2016). Modular virus-like particles for sublingual vaccination against group A streptococcus. Vaccine, 34 (51), 6472-6480. doi: 10.1016/j.vaccine.2016.11.008

Modular virus-like particles for sublingual vaccination against group A streptococcus

2016

Journal Article

Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccination

Waneesorn, Jarurin, Wibowo, Nani, Bingham, John, Middelberg, Anton P. J. and Lua, Linda H.L. (2016). Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccination. Vaccine, 36 (22), 3064-3071. doi: 10.1016/j.vaccine.2016.11.058

Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccination

2016

Journal Article

Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen

Tekewe, Alemu, Fan, Yuanyuan, Tan, Emilyn, Middelberg, Anton P. J. and Lua, Linda H. L. (2016). Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen. Biotechnology and Bioengineering, 114 (2), 397-406. doi: 10.1002/bit.26068

Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen

2016

Journal Article

Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle

Tekewe, Alemu, Connors, Natalie K., Middelberg, Anton P. J. and Lua, Linda H. L. (2016). Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle. Protein Science, 25 (8), 1507-1516. doi: 10.1002/pro.2953

Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle

2016

Conference Publication

Sublingual vaccination with self-adjuvanting virus-like particles against Group A streptococcus elicit protective immunity in systemic and mucosal sites: implication for allergen-specific immunotherapy

Kong, I, Seth, A., Yang, J-Y, Lee, S-H, Lee, Y-S, Kim, Y., Middelberg, A., Wibowo, N., Lua, L. and Kweon, M-N (2016). Sublingual vaccination with self-adjuvanting virus-like particles against Group A streptococcus elicit protective immunity in systemic and mucosal sites: implication for allergen-specific immunotherapy. Meeting of the European Academy of Allergy and Clinical Immunology, Vienna, Austria, Jun 11-15, 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Sublingual vaccination with self-adjuvanting virus-like particles against Group A streptococcus elicit protective immunity in systemic and mucosal sites: implication for allergen-specific immunotherapy

2015

Journal Article

Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particle

Lua, Linda H.L., Fan, Yuanyuan, Chang, Cindy, Connors, Natalie K. and Middelberg, Anton P.J. (2015). Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particle. Vaccine, 33 (44), 5937-5944. doi: 10.1016/j.vaccine.2015.09.017

Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particle

2015

Journal Article

Vaccine

Wibowo, Nani, Lua, Linda Hwee-Lin, Jungbauer, Alois and Ma, Guanghui (2015). Vaccine. Vaccine Engineering, 33 (44), 5889-5889. doi: 10.1016/j.vaccine.2015.10.002

Vaccine

2015

Journal Article

Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza

Wibowo, Nani, Wu, Yang, Fan, Yuanyuan, Meers, Joanne, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza. Vaccine, 33 (44), 5960-5965. doi: 10.1016/j.vaccine.2015.08.100

Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza

2015

Journal Article

Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes

Abidin, R.S., Lua, L.H.L., Middelberg, A.P.J. and Sainsbury, F. (2015). Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes. Protein Science, 24 (11), 1820-1828. doi: 10.1002/pro.2775

Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes

2015

Journal Article

Biomolecular engineering of virus-like particles aided by computational chemistry methods

Zhang, Lin, Lua, Linda H. L., Middelberg, Anton P. J., Sun, Yan and Connors, Natalie K. (2015). Biomolecular engineering of virus-like particles aided by computational chemistry methods. Chemical Society Reviews, 44 (23), 8608-8618. doi: 10.1039/c5cs00526d

Biomolecular engineering of virus-like particles aided by computational chemistry methods

2015

Journal Article

A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidates

Tekewe, Alemu, Connors, Natalie K., Sainsbury, Frank, Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidates. Biochemical Engineering Journal, 100, 50-58. doi: 10.1016/j.bej.2015.04.004

A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidates

2015

Journal Article

Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent Manner

Seth, Arjun, Ritchie, Fiona K., Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent Manner. PLoS One, 10 (3) 0117203, e0117203-e0117203. doi: 10.1371/journal.pone.0117203

Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent Manner

2015

Journal Article

Development of picornavirus-like particle vaccines

Somasundaram, Balaji and Lua, Linda H. L. (2015). Development of picornavirus-like particle vaccines. Pharmaceutical Bioprocessing, 3 (1), 45-49. doi: 10.4155/pbp.14.39

Development of picornavirus-like particle vaccines

2015

Journal Article

Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect Cells

Somasundaram, Balaji, Chang, Cindy, Fan, Yuan Y., Lim, Pei-Yin, Cardosa, Jane and Lua, Linda (2015). Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect Cells. Methods, 95, 38-45. doi: 10.1016/j.ymeth.2015.09.023

Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect Cells

2014

Journal Article

The economics of virus-like particle and capsomere vaccines

Chuan, Yap P., Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2014). The economics of virus-like particle and capsomere vaccines. Biochemical Engineering Journal, 90, 255-263. doi: 10.1016/j.bej.2014.06.005

The economics of virus-like particle and capsomere vaccines

2014

Journal Article

Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations

Zhang, Lin, Tang, Ronghong, Bai, Shu, Connors, Natalie K., Lua, Linda H. L., Chuan, Yap P., Middelberg, Anton P. J. and Sun, Yan (2014). Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations. PLoS One, 9 (9) e107313, e107313.1-e107313.12. doi: 10.1371/journal.pone.0107313

Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations