![Dr Nicholas Clark](/sites/default/files/profiles/15140.jpeg)
Overview
Background
An ecologist by training – I hold a B.Sc. (Hons) in Marine Ecology from the University of North Carolina, Wilmington and a Ph.D. in Ecological Modelling from Griffith University. I am broadly interested in exploring new ways to (1) understand how natural communities are formed and (2) predict how they will change over time. As an Amplify Fellow at UQ, my current research focuses on developing computational tools and adapting techniques from epidemiology and statistical forecasting to study how organisms and ecosystems respond to environmental change. This work is being applied to investigate natural dynamics for a range of natural systems including host-parasite interactions, wildlife populations and veterinary diseases.
I am an active member of the R community and have written and/or maintain several popular R packages. For example, I’m a lead developer on the MRFcov package for multivariate conditional random fields analyses. I also wrote the mvgam R package for fitting dynamic Generalised Additive Models to analyse and forecast multivariate ecological time series, and I regularly provide training seminars and workshops to help researchers learn techniques in ecological data analysis.
I am currently seeking Honours and PhD candidates with interests and/or skills in veterinary epidemiology, spatial / spatiotemporal modeling and quantitative ecology.
Availability
- Dr Nicholas Clark is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Griffith University
Research interests
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Using forecasts to anticipate how ecosystems respond to environmental change
I am leading projects to develop new stastical and machine learning models that aim to advance our ability to predict and forecast ecological change. Expected applications of this work cover many fields where time series are very important, including conservation prioritisation, agriculture, species distribution modeling and biosecurity. Currently seeking both Honours and PhD students who are interested in ecological forecasting.
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The macroecology and biogeography of infectious dieases
This work aims to describe large-scale patterns in the distributions of wildlife and their pathogens to identify processes governing ecological community assembly and the spread of pathogens. I'll be very happy to accept Honours or PhD students who are interested in biogeography, wildlife research and infectious disease epidemiology.
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The epidemiology of animal pathogens across the human-wildlife interface
I am interested in using molecular genetics and epidemiology to improve our understanding of how pathogen infection rates and emergence will change as human encroachment alters natural environments. This work mostly focuses on wildlife and domestic animals, but it can also be used to study human diseases. I'll be very happy to accept Honours or PhD students who are interested in this line of work.
Research impacts
My research is geared towards understanding how ecological communities, pathogen infection rates and pathogen emergence will change as climate change and human encroachment continue to alter natural environments. This work has generated translational benefits by helping to provide insights into factors that can be targeted to reduce the spread of pathogens in our animals and how to build better models for understanding wildlife responses to climate change. Some key media coverage of this body of work includes:
Ecological Forecasting with Dynamic Generalized Additive Models
Detecting how ecological communities respond to temperature changes
Understanding parasite spread through wildlife: the crucial role of statistical models
Adapting statistical network models to identify biotic interactions in changing communities
Using evolutionary models to trace the emergence of harmful viruses in pet dogs
Tracing the spread of fleas from pets to wildlife and vice versa
Works
Search Professor Nicholas Clark’s works on UQ eSpace
2023
Journal Article
Direct and indirect viral associations predict coexistence in wild plant virus communities
Norberg, Anna, Susi, Hanna, Sallinen, Suvi, Baran, Pezhman, Clark, Nicholas J. and Laine, Anna-Liisa (2023). Direct and indirect viral associations predict coexistence in wild plant virus communities. Current Biology, 33 (9), 1665-1676.e4. doi: 10.1016/j.cub.2023.03.022
2023
Journal Article
Using a gradient boosted model for case ascertainment from free-text veterinary records
Kennedy, Uttara, Paterson, Mandy and Clark, Nicholas (2023). Using a gradient boosted model for case ascertainment from free-text veterinary records. Preventive Veterinary Medicine, 212 105850, 1-8. doi: 10.1016/j.prevetmed.2023.105850
2023
Journal Article
Modelling modifiable factors associated with the probability of human rabies deaths among self-reported victims of dog bites in Abuja, Nigeria
Mshelbwala, Philip P., J. Soares Magalhães, Ricardo, Weese, J. Scott, Ahmed, Nasir O., Rupprecht, Charles E. and Clark, Nicholas J. (2023). Modelling modifiable factors associated with the probability of human rabies deaths among self-reported victims of dog bites in Abuja, Nigeria. PLoS Neglected Tropical Diseases, 17 (2) e0011147, 1-20. doi: 10.1371/journal.pntd.0011147
2022
Journal Article
Polymicrobial foot infection patterns are common and associated with treatment failure
Barshes, Neal R., Clark, Nicholas J., Bidare, Deeksha, Dudenhoeffer, J. H., Mindru, Cezarina and Rodriguez-Barradas, Maria C. (2022). Polymicrobial foot infection patterns are common and associated with treatment failure. Open Forum Infectious Diseases, 9 (10) ofac475, 1-6. doi: 10.1093/ofid/ofac475
2022
Journal Article
Profiling risk factors for household and community spatiotemporal clusters of Q fever notifications in Queensland between 2002 and 2017
Proboste, Tatiana, Clark, Nicholas J., Tozer, Sarah, Wood, Caitlin, Lambert, Stephen B. and Soares Magalhães, Ricardo J. (2022). Profiling risk factors for household and community spatiotemporal clusters of Q fever notifications in Queensland between 2002 and 2017. Pathogens, 11 (8) 830, 1-12. doi: 10.3390/pathogens11080830
2022
Journal Article
Spatiotemporal heterogeneity and determinants of canine rabies evidence at Local Government Area Level in Nigeria: implications for rabies prevention and control
Mshelbwala, Philip P., Weese, J. Scott, Clark, Nicholas J., Tekki, Ishaya, Chakma, Shovon, Shamaki, David, Mamun, Abdullah A., Rupprecht, Charles E. and Soares Magalhães, Ricardo J. (2022). Spatiotemporal heterogeneity and determinants of canine rabies evidence at Local Government Area Level in Nigeria: implications for rabies prevention and control. One Health, 14 100378, 1-9. doi: 10.1016/j.onehlt.2022.100378
2022
Journal Article
Haemoprotozoa in wild short‐beaked echidnas (Tachyglossus aculeatus)
Hill, A.G., Boyd, S.P., Clark, N.J. and Proboste, T. (2022). Haemoprotozoa in wild short‐beaked echidnas (Tachyglossus aculeatus). Australian Veterinary Journal, 100 (3), 130-134. doi: 10.1111/avj.13132
2021
Conference Publication
Role of live poultry movement on environmental contamination patterns of avian influenza A viruses circulating in live bird markets, Dhaka, Bangladesh
Chakma, Shovon, Mshelbwala, Philip P., Samad, Mohammed Abdus, Karim, Md Rezaul, Giasuddin, Mohammad, Akwar, Holy, Hasan, Zakiul, Nasrin, Tanzinah, Brum, Eric, Osmani, Muzaffar G., Islam, S.K. Shaheenur, Ibrahim, Nelima, McKenzie, Joanna, Clark, Nicholas J., Islam, Zahir, Sly, Peter and Soares Magalhães, Ricardo J. (2021). Role of live poultry movement on environmental contamination patterns of avian influenza A viruses circulating in live bird markets, Dhaka, Bangladesh. 7th One Health Aotearoa Symposium, Wellington, New Zealand, 7-8 December 2021.
2021
Conference Publication
Spatial patterns of canine rabies evidence at the local government area level in Nigeria: association with socioeconomic and ecological determinants
Mshelbwala, Philip P., Weese, J. Scott, Tekki, Ishaya, Chakma, Shovon, Shamaki, David, Mamun, Abdullah A., Clark, Nicholas J., Rupprecht, Charles E. and Soares Magalhães, Ricardo J. (2021). Spatial patterns of canine rabies evidence at the local government area level in Nigeria: association with socioeconomic and ecological determinants. 7th One Heath Aotearoa Symposium, Wellington, New Zealand, 6-7 December 2021.
2021
Journal Article
Global drivers of avian haemosporidian infections vary across zoogeographical regions
Fecchio, Alan, Clark, Nicholas J., Bell, Jeffrey A., Skeen, Heather R., Lutz, Holly L., De La Torre, Gabriel M., Vaughan, Jefferson A., Tkach, Vasyl V., Schunck, Fabio, Ferreira, Francisco C., Braga, Érika M., Lugarini, Camile, Wamiti, Wanyoike, Dispoto, Janice H., Galen, Spencer C., Kirchgatter, Karin, Sagario, M. Cecilia, Cueto, Victor R., González‐Acuña, Daniel, Inumaru, Mizue, Sato, Yukita, Schumm, Yvonne R., Quillfeldt, Petra, Pellegrino, Irene, Dharmarajan, Guha, Gupta, Pooja, Robin, V. V., Ciloglu, Arif, Yildirim, Alparslan ... Kamath, Pauline (2021). Global drivers of avian haemosporidian infections vary across zoogeographical regions. Global Ecology and Biogeography, 30 (12) geb.13390, 2393-2406. doi: 10.1111/geb.13390
2021
Journal Article
MrIML: Multi‐response interpretable machine learning to model genomic landscapes
Fountain‐Jones, Nicholas M., Kozakiewicz, Christopher P., Forester, Brenna R., Landguth, Erin L., Carver, Scott, Charleston, Michael, Gagne, Roderick B., Greenwell, Brandon, Kraberger, Simona, Trumbo, Daryl R., Mayer, Michael, Clark, Nicholas J. and Machado, Gustavo (2021). MrIML: Multi‐response interpretable machine learning to model genomic landscapes. Molecular Ecology Resources, 21 (8) 1755-0998.13495, 2766-2781. doi: 10.1111/1755-0998.13495
2021
Journal Article
Tick paralysis in Australian birds caused by Ixodes holocyclus
Hill, A. G., Clark, N. J. and Tokonami, F. (2021). Tick paralysis in Australian birds caused by Ixodes holocyclus. Australian Veterinary Journal, 99 (12) avj.13119, 1-7. doi: 10.1111/avj.13119
2021
Journal Article
Perceptions of dog owners towards canine gastrointestinal parasitism and associated human health risk in Southeast Queensland
Nguyen, Tu, Clark, Nicholas, Jones, Malcolm K., Herndon, Aaron, Mallyon, John, Soares Magalhaes, Ricardo J. and Abdullah, Swaid (2021). Perceptions of dog owners towards canine gastrointestinal parasitism and associated human health risk in Southeast Queensland. One Health, 12 100226, 100226. doi: 10.1016/j.onehlt.2021.100226
2021
Journal Article
Coxiella burnetii in the environment: a systematic review and critical appraisal of sampling methods
Abeykoon, A. M. Hasanthi, Clark, Nicholas Joshua, Soares Magalhaes, Ricardo Jorge, Vincent, Gemma Anne, Stevenson, Mark Anthony, Firestone, Simon Matthew and Wiethoelter, Anke Katrin (2021). Coxiella burnetii in the environment: a systematic review and critical appraisal of sampling methods. Zoonoses and Public Health, 68 (3), 165-181. doi: 10.1111/zph.12791
2020
Journal Article
Robust geographical determinants of infection prevalence and a contrasting latitudinal diversity gradient for haemosporidian parasites in Western Palearctic birds
Clark, Nicholas J., Drovetski, Sergei V. and Voelker, Gary (2020). Robust geographical determinants of infection prevalence and a contrasting latitudinal diversity gradient for haemosporidian parasites in Western Palearctic birds. Molecular Ecology, 29 (16) mec.15545, 3131-3143. doi: 10.1111/mec.15545
2020
Journal Article
Genetic analysis of porcine circovirus type 2 (PCV2) in Queensland, Australia
Mone, N.K., Clark, N.J., Kyaw‐Tanner, M., Turni, C., Barnes, T.S., Parke, C.R., Alawneh, JA, Blackall, P.J. and Meers, J. (2020). Genetic analysis of porcine circovirus type 2 (PCV2) in Queensland, Australia. Australian Veterinary Journal, 98 (8) avj.12952, 388-395. doi: 10.1111/avj.12952
2020
Journal Article
Unravelling animal exposure profiles of human Q fever cases in Queensland, Australia, using natural language processing
Clark, Nicholas J., Tozer, Sarah, Wood, Caitlin, Firestone, Simon M., Stevenson, Mark, Caraguel, Charles, Chaber, Anne‐Lise, Heller, Jane and Soares Magalhães, Ricardo J. (2020). Unravelling animal exposure profiles of human Q fever cases in Queensland, Australia, using natural language processing. Transboundary and Emerging Diseases, 67 (5) tbed.13565, 2133-2145. doi: 10.1111/tbed.13565
2020
Journal Article
Parasite associations predict infection risk: incorporating co-infections in predictive models for neglected tropical diseases
Clark, Nicholas J., Owada, Kei, Ruberanziza, Eugene, Ortu, Giuseppina, Umulisa, Irenee, Bayisenge, Ursin, Mbonigaba, Jean Bosco, Mucaca, Jean Bosco, Lancaster, Warren, Fenwick, Alan, Soares Magalhães, Ricardo J. and Mbituyumuremyi, Aimable (2020). Parasite associations predict infection risk: incorporating co-infections in predictive models for neglected tropical diseases. Parasites and Vectors, 13 (1) 138, 138. doi: 10.1186/s13071-020-04016-2
2019
Journal Article
Mapping Schistosoma mansoni endemicity in Rwanda: a critical assessment of geographical disparities arising from circulating cathodic antigen versus Kato-Katz diagnostics
Clark, Nicholas J., Umulisa, Irenee, Ruberanziza, Eugene, Owada, Kei, Colley, Daniel G., Ortu, Giuseppina, Campbell, Carl H., Ruzindana, Emmanuel, Lancaster, Warren, Mbonigaba, Jean Bosco, Mbituyumuremyi, Aimable, Fenwick, Alan, Soares Magalhaes, Ricardo J. and Turate, Innocent (2019). Mapping Schistosoma mansoni endemicity in Rwanda: a critical assessment of geographical disparities arising from circulating cathodic antigen versus Kato-Katz diagnostics. PLoS Neglected Tropical Diseases, 13 (9) e0007723, e0007723. doi: 10.1371/journal.pntd.0007723
2019
Journal Article
An inverse latitudinal gradient in infection probability and phylogenetic diversity for Leucocytozoon blood parasites in New World birds
Fecchio, Alan, Bell, Jeffrey A., Bosholn, Mariane, Vaughan, Jefferson A., Tkach, Vasyl V., Lutz, Holly L., Cueto, Victor R., Gorosito, Cristian A., González‐Acuña, Daniel, Stromlund, Chad, Kvasager, Danielle, Comiche, Kiba J. M., Kirchgatter, Karin, Pinho, João B., Berv, Jacob, Anciães, Marina, Fontana, Carla S., Zyskowski, Kristof, Sampaio, Sidnei, Dispoto, Janice H., Galen, Spencer C., Weckstein, Jason D. and Clark, Nicholas J. (2019). An inverse latitudinal gradient in infection probability and phylogenetic diversity for Leucocytozoon blood parasites in New World birds. Journal of Animal Ecology, 89 (2) 1365-2656.13117, 423-435. doi: 10.1111/1365-2656.13117
Funding
Past funding
Supervision
Availability
- Dr Nicholas Clark is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Forecasting ecosystem responses to environmental change
There is a growing consensus that using models to anticipate the future is vital to mitigate the impacts of environmental change on ecosystems. Yet most ecological models are one-off attempts to predict what ecosystems might be like in many years or decades. This makes it hard for decision-makers to use these models. It also favours models that are not easily scrutinised and improved. This research will use an iterative cycle to 1) forecast how species occurrences and abundances will change over short timescales; 2) use predictions to inspect model failures and 3) improve models so that we can continue to learn. This represents a new way of thinking in ecology that, like weather forecasting, has the power to advance our understanding of ecological processes.
I am looking for students who want to work within a vibrant team of quantitative ecologists and spatio-temporal modellers to tackle interesting questions in ecological modeling and forecasting. This project will help develop the candidate’s skills in critical thinking, project management, data management and analysis, writing and communication. Expected applications of the project are incredibly diverse, meaning the student will be well prepared for a future career in research or with government and non-government land management, biosecurity or conservation agencies.
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How is global change impacting ecological communities?
Global change is heavily impacting natural ecosystems thorough climate change, landscape alterations, invasive species and many other processes. We are offering projects investigating time series from around the world to ask key questions such as:
Do ensemble forecasts outperform forecasts from individual models in ecological settings?
How are wildlife populations from different groups (insects, mammals, birds) responding?
How does climate variablity affect population dynamics?
How does population variance and stability change over time and in relation to climate variation?
How are Australia's marine ecosystem responding to climate change?
We are looking for students interested in understanding how globally pressing changes are impacting our wildlife communities. Ideal candidates will have demonstrated skills in statistical modelling, coding experience (in any programming language), and strong written and communication skills. You do not need to have experience in wildlife ecology, but you must have a keen interest to learn.
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Developing new statistical methods to advance near-term forecasting
What will nature look like in the future? This question is difficult to answer because ecology, and ecosystem dynamics, are very complex. The abundances of species, for example, fluctuate for many reasons. Food and shelter availability limit survival. Biotic interactions affect colonization and vital rates. Severe weather events and climate variation alter habitat suitability. Current changes in abundance can have carry-on effects on future abundance, irrespective of local conditions. These sources of variation make it difficult to understand, let alone predict, ecosystem change. Another problem when trying to understand these effects is that common statistical methods for analysing time series are not suitable for dealing with most ecological data (which can have many zeros, missing values and are often represented as multivariate count data).
This project aims to develop new modeling tools that will allow researchers around the globe to better analyse their data. Work will centre around the development of Bayesian dynamic models for time series and forecasting purposes. Ideal candidates should be interested in software development and statistical programming, so candidates with backgrounds in computer science or some othe field that provides skills in programming will be well placed to make an impact here. It is not necessary that you have strong skills in time series analysis or forecasting, but you should be keen to learn about these fields.
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Modeling and forecasting paralysis tick infestation rates in Australia
Tick paralysis, caused by neurotoxins contained in the saliva of paralysis ticks, is a life-threatening condition for dogs and cats requiring immediate medical attention. In Australia tick paralysis is a leading cause of emergency admissions, with tens of thousands of tick paralysis cases admitted to veterinary emergency services each year. While preventative treatments and avoidance of tick-prone areas during periods of heightened risk are effective reduction measures, surveillance systems are inadequate to provide timely information to clinicians and pet owners located in areas most at-risk.
Working as part of a vibrant research team involving a diversity of collaborators, students will benefit in the following ways:
(1) Experience in data mining and generating critical summaries for time series data
(2) Quantitative analysis of multistructure datasets
(3) Contributing to the planning, writing and submission of peer-reviewed publications
We are looking for students who are interested in the health of pets and in using data to inform disease management. Ideal candidates will have demonstrated skills in statistical modeling, coding experience (in any programming language), and strong written and communication skills. You do not need to have experience in veterinary epidemiology, but you must have a keen interest to learn.
Supervision history
Current supervision
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Doctor Philosophy
Towards explainable multi-response models for predicting pathogen infection risks
Principal Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Forecasting ecosystem responses to environmental change
Principal Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Epidemiology of feline upper respiratory tract infections in shelter cats in Australia
Principal Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Epidemiology of feline upper respiratory tract infections in shelter cats at RSPCA Queensland
Principal Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Towards explainable multi-response models for predicting pathogen infection risks
Principal Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Spatial epidemiological approach to target health education and promotion interventions to eliminate paediatric rabies in Guangxi, China
Associate Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Evaluation of Integrated Surveillance of Antimicrobial Resistance in South and South East Asian Countries
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Professor Peter Sly, Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Spatial epidemiological approaches to support local One Health strategies to achieve rabies infection control and elimination
Associate Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka¿s metropolitan area, Bangladesh
Associate Advisor
Other advisors: Professor Peter Sly, Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Prevalence of ticks and tick-borne diseases and other parasitic diseases in wild and free roaming canids in Queensland, Australia.
Associate Advisor
Other advisors: Dr Justine Gibson, Dr Swaid Abdullah
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Doctor Philosophy
Australian Wet Tropics vertebrate responses to multiple threats
Associate Advisor
Other advisors: Dr Andrew Letten, Associate Professor Matthew Luskin
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Doctor Philosophy
Investigations into the importance of antimicrobial residues in the surveillance of antimicrobial resistance in peri-urban dairy farms of Nepal
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Professor Peter Sly, Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka¿s metropolitan area, Bangladesh
Associate Advisor
Other advisors: Professor Peter Sly, Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Evolutionary pathways and molecular characterization of Influenza Viruses at high-risk human-poultry interfaces in Bangladesh
Associate Advisor
Other advisors: Professor Ricardo Soares Magalhaes
Completed supervision
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2023
Doctor Philosophy
Epidemiology of canine-mediated rabies in Nigeria
Principal Advisor
Other advisors: Professor Joanne Meers
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2020
Doctor Philosophy
Genetic analysis tools to investigate the role of wildlife in disease transmission in modified environments
Associate Advisor
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2020
Doctor Philosophy
Ecological genetics of dugongs (Dugong dugon) in Queensland
Associate Advisor
Other advisors: Dr Justine Gibson, Dr Janet Lanyon
Media
Enquiries
Contact Dr Nicholas Clark directly for media enquiries about:
- Community ecology
- Disease ecology
- Ecological modeling
- Forecasting
- Host-parasite interactions
Need help?
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