Dr

Tom Schultz

Email: 
Phone: 
+61 7 344 36970

Background

Dr Tom Schultz is a molecular immunologist and early career researcher at the UQ Frazer Institute who studies the molecular and cellular biology of innate immune receptors. His research primarily focuses on molecular mechanisms of Toll-like receptor (TLR) signalling in the context of mycobacterial and Gram-negative bacterial infection of macrophages.

Availability

Dr Tom Schultz is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Immunology Innate immunity

Qualifications

  • Bachelor (Honours) of Biomedical Science, The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Tom Schultz’s works on UQ eSpace

10 works between 2014 and 2024
All (10) Journal Article (7) Conference Publication (2) Other Outputs (1)

1 - 10 of 10 works

2024

Journal Article

Myddosomes in Toll-like receptor signaling-one to bind and rule them all

Mathmann, Carmen D., Schultz, Thomas E., Cadena, Leslie C. Dominguez and Blumenthal, Antje (2024). Myddosomes in Toll-like receptor signaling-one to bind and rule them all. Immunology and Cell Biology, 102 (9), 752-756. doi: 10.1111/imcb.12816

Myddosomes in Toll-like receptor signaling-one to bind and rule them all

2023

Conference Publication

SPATIOTEMPORAL REGULATION OF RP105 SUBCELLULAR LOCALIZATION SHAPES ENDOSOMAL TLR4 SIGNALING

Mathmann, Carmen, Schultz, Thomas, Ongtengco, Cherica Felize J., Dalton, Emma, Domínguez Cadena, Leslie C., Zamoshnikova, Alina, Stow, Jennifer L. and Blumenthal, Antje (2023). SPATIOTEMPORAL REGULATION OF RP105 SUBCELLULAR LOCALIZATION SHAPES ENDOSOMAL TLR4 SIGNALING. IMMUNOLOGY 2023 Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.160.06

SPATIOTEMPORAL REGULATION OF RP105 SUBCELLULAR LOCALIZATION SHAPES ENDOSOMAL TLR4 SIGNALING

2022

Journal Article

Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis

Donovan, Meg L., Bielefeldt‐Ohmann, Helle, Rollo, Rachel F., McPherson, Stephen, Schultz, Thomas E., Mori, Giorgia, Kling, Jessica C. and Blumenthal, Antje (2022). Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis. Immunology, 169 (1), 13-26. doi: 10.1111/imm.13606

Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis

2021

Journal Article

Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection

Domínguez Cadena, Leslie C., Schultz, Thomas E., Zamoshnikova, Alina, Donovan, Meg L., Mathmann, Carmen D., Yu, Chien-Hsiung, Mori, Giorgia, Stow, Jennifer L and Blumenthal, Antje (2021). Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection. Immunology and Cell Biology, 99 (10), 1067-1076. doi: 10.1111/imcb.12503

Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection

2018

Other Outputs

Characterisation of the molecular mechanisms of RP105-dependent macrophage activation

Schultz, Thomas E. (2018). Characterisation of the molecular mechanisms of RP105-dependent macrophage activation. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2019.95

Characterisation of the molecular mechanisms of RP105-dependent macrophage activation

2018

Journal Article

The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties

Schultz, Thomas E., Wiesmüller, Karl-Heinz, Lucas, Megan, Dobos, Karen M., Baxter, Alan G. and Blumenthal, Antje (2018). The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties. Journal of Leukocyte Biology, 103 (2), 311-319. doi: 10.1002/JLB.2MA0517-190RR

The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties

2017

Journal Article

Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences

Donovan, Meg L., Schultz, Thomas E., Duke, Taylor J. and Blumenthal, Antje (2017). Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences. Frontiers in Immunology, 8 (NOV) 1633, 1-16. doi: 10.3389/fimmu.2017.01633

Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences

2017

Journal Article

The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications

Schultz, Thomas E. and Blumenthal, Antje (2017). The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications. Journal of Leukocyte Biology, 101 (1), 183-192. doi: 10.1189/jlb.2VMR1215-582R

The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications

2015

Journal Article

RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection

Yu, Chien-Hsiung, Micaroni, Massimo, Puyskens, Andreas, Schultz, Thomas E., Yeo, Jeremy Changyu, Stanley, Amanda C., Lucas, Megan, Kurihara, Jade, Dobos, Karen M., Stow, Jennifer L. and Blumenthal, Antje (2015). RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection. Journal of Immunology, 195 (8), 3890-3900. doi: 10.4049/jimmunol.1500017

RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection

2014

Conference Publication

Interference with Wnt pathway improves host control of Listeria monocytogenes in vivo

Gatica-Andrades, M. D., Nguyen, T. T. K., Schultz, T. E., Wyer, O. J. K., Melo-Bolivar, J., Walker, M. J., Frazer, I. H., Barnett, T. C. and Blumenthal, A. (2014). Interference with Wnt pathway improves host control of Listeria monocytogenes in vivo. British Society for Immunology Annual Congress 2014, Brighton, United Kingdom, 1-4 December 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/imm.12406

Interference with Wnt pathway improves host control of Listeria monocytogenes in vivo

Current funding

  • 2023 - 2025
    Longitudinal profiling of TLR4 endocytosis and cellular reactivation in a Gram-negative sepsis cohort
    TRI Leading Innovations through New Collaborations Scheme
    Open grant

Availability

Dr Tom Schultz is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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