Overview
Background
Dr Tom Schultz is a molecular immunologist and early career researcher at the UQ Frazer Institute who studies the molecular and cellular biology of innate immune receptors. His research primarily focuses on molecular mechanisms of Toll-like receptor (TLR) signalling in the context of mycobacterial and Gram-negative bacterial infection of macrophages.
Availability
- Dr Tom Schultz is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Biomedical Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Tom Schultz’s works on UQ eSpace
2024
Journal Article
Myddosomes in Toll-like receptor signaling-one to bind and rule them all
Mathmann, Carmen D., Schultz, Thomas E., Cadena, Leslie C. Dominguez and Blumenthal, Antje (2024). Myddosomes in Toll-like receptor signaling-one to bind and rule them all. Immunology and Cell Biology, 102 (9), 752-756. doi: 10.1111/imcb.12816
2023
Conference Publication
SPATIOTEMPORAL REGULATION OF RP105 SUBCELLULAR LOCALIZATION SHAPES ENDOSOMAL TLR4 SIGNALING
Mathmann, Carmen, Schultz, Thomas, Ongtengco, Cherica Felize J., Dalton, Emma, Domínguez Cadena, Leslie C., Zamoshnikova, Alina, Stow, Jennifer L. and Blumenthal, Antje (2023). SPATIOTEMPORAL REGULATION OF RP105 SUBCELLULAR LOCALIZATION SHAPES ENDOSOMAL TLR4 SIGNALING. IMMUNOLOGY 2023 Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.160.06
2022
Journal Article
Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis
Donovan, Meg L., Bielefeldt‐Ohmann, Helle, Rollo, Rachel F., McPherson, Stephen, Schultz, Thomas E., Mori, Giorgia, Kling, Jessica C. and Blumenthal, Antje (2022). Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis. Immunology, 169 (1), 13-26. doi: 10.1111/imm.13606
2021
Journal Article
Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection
Domínguez Cadena, Leslie C., Schultz, Thomas E., Zamoshnikova, Alina, Donovan, Meg L., Mathmann, Carmen D., Yu, Chien-Hsiung, Mori, Giorgia, Stow, Jennifer L and Blumenthal, Antje (2021). Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection. Immunology and Cell Biology, 99 (10), 1067-1076. doi: 10.1111/imcb.12503
2018
Other Outputs
Characterisation of the molecular mechanisms of RP105-dependent macrophage activation
Schultz, Thomas E. (2018). Characterisation of the molecular mechanisms of RP105-dependent macrophage activation. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2019.95
2018
Journal Article
The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties
Schultz, Thomas E., Wiesmüller, Karl-Heinz, Lucas, Megan, Dobos, Karen M., Baxter, Alan G. and Blumenthal, Antje (2018). The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties. Journal of Leukocyte Biology, 103 (2), 311-319. doi: 10.1002/JLB.2MA0517-190RR
2017
Journal Article
Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences
Donovan, Meg L., Schultz, Thomas E., Duke, Taylor J. and Blumenthal, Antje (2017). Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences. Frontiers in Immunology, 8 (NOV) 1633, 1-16. doi: 10.3389/fimmu.2017.01633
2017
Journal Article
The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications
Schultz, Thomas E. and Blumenthal, Antje (2017). The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications. Journal of Leukocyte Biology, 101 (1), 183-192. doi: 10.1189/jlb.2VMR1215-582R
2015
Journal Article
RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection
Yu, Chien-Hsiung, Micaroni, Massimo, Puyskens, Andreas, Schultz, Thomas E., Yeo, Jeremy Changyu, Stanley, Amanda C., Lucas, Megan, Kurihara, Jade, Dobos, Karen M., Stow, Jennifer L. and Blumenthal, Antje (2015). RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection. Journal of Immunology, 195 (8), 3890-3900. doi: 10.4049/jimmunol.1500017
2014
Conference Publication
Interference with Wnt pathway improves host control of Listeria monocytogenes in vivo
Gatica-Andrades, M. D., Nguyen, T. T. K., Schultz, T. E., Wyer, O. J. K., Melo-Bolivar, J., Walker, M. J., Frazer, I. H., Barnett, T. C. and Blumenthal, A. (2014). Interference with Wnt pathway improves host control of Listeria monocytogenes in vivo. British Society for Immunology Annual Congress 2014, Brighton, United Kingdom, 1-4 December 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/imm.12406
Funding
Current funding
Supervision
Availability
- Dr Tom Schultz is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Investigating molecular mechanisms of RP105-dependent macrophage activation during mycobacterial infection
Associate Advisor
Other advisors: Professor Matt Sweet, Professor Antje Blumenthal
Media
Enquiries
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