
Overview
Background
Dr. Sherman Leung is the Head of Research Operations at Wesley Research Institute - the research partner of UnitingCare. UnitingCare is the largest private employer in Queensland, encompassing four hospitals (The Wesley Hospital, St. Andrew's War Memorial Hospital, Buderim Private Hospital and St. Stephen's Hospital), as well as significant community-based offerings through Lifeline, Blue Care, Family and Disability Services, and ARRCS.
Dr. Leung is a PhD trained scientist, conducting his research training at Mater Research Institute, The University of Queensland, during which his research was published in highly regarded peer-reviewed journals, including in 'Diabetes', receiving the Cover Image, an 'In This Issue' feature, and shared across the Australian-wide 7 Network news.
He has extensive experience in clinical trials, having worked at Microba Life Sciences, an ASX-listed biotechnology start-up, and Nucleus Network, Australia’s largest early phase clinical trial site having overseen the conduct of several high-profile COVID-19 projects including Nuvaxovid by Novavax that has been granted emergency authorisation in 40 countries including by the TGA, EMEA & FDA.
He contributes his spare time to the greater good through numerous initiatives in the industry including being a Board Director of the Australian Clinical Trials Alliance (ACTA), Editorial Board for 'Trials' – a BMC journal promoting all aspects of trials including methods, processes and non-significant outcomes for transparency in the field – being a former member of the Metro North Human Research Ethics Committee (HREC), and offering regular guest classrooms on clinical trials, informed consent and ethics at The University of Queensland.
Availability
- Dr Sherman Leung is:
- Not available for supervision
Works
Search Professor Sherman Leung’s works on UQ eSpace
2023
Journal Article
Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes
Leung, Sherman S., Lenchik, Nataliya, Mathews, Clayton, Pugliese, Alberto, McCarthy, Domenica A., Le Bagge, Selena, Ewing, Adam, Harris, Mark, Radford, Kristen J., Borg, Danielle J., Gerling, Ivan and Forbes, Josephine M. (2023). Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Scientific Reports, 13 (1) 12948, 1-15. doi: 10.1038/s41598-023-39243-x
2022
Journal Article
Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells
Leung, Sherman S., Borg, Danielle J., McCarthy, Domenica A., Boursalian, Tamar E., Cracraft, Justen, Zhuang, Aowen, Fotheringham, Amelia K., Flemming, Nicole, Watkins, Thomas, Miles, John J., Groop, Per-Henrik, Scheijen, Jean L., Schalkwijk, Casper G., Steptoe, Raymond J., Radford, Kristen J., Knip, Mikael and Forbes, Josephine M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71 (9), 1994-2008. doi: 10.2337/db22-0177
2021
Journal Article
Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model
Borg, Danielle J., Faridi, Pouya, Giam, Kai Lin, Reeves, Peta, Fotheringham, Amelia K., McCarthy, Domenica A., Leung, Sherman, Ward, Micheal S., Harcourt, Brooke E., Ayala, Rochelle, Scheijen, Jean L., Briskey, David, Dudek, Nadine L., Schalkwijk, Casper G., Steptoe, Raymond, Purcell, Anthony W. and Forbes, Josephine M. (2021). Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model. Metabolites, 11 (7) 426, 1-21. doi: 10.3390/metabo11070426
2021
Journal Article
Advanced glycation end products as predictors of renal function in youth with type 1 diabetes
Forbes, Josephine M., Le Bagge, Selena, Righi, Samuel, Fotheringham, Amelia K., Gallo, Linda A., McCarthy, Domenica A., Leung, Sherman, Baskerville, Tracey, Nisbett, Janelle, Morton, Adam, Teasdale, Stephanie, D'Silva, Neisha, Barrett, Helen, Jones, Timothy, Couper, Jennifer, Donaghue, Kim, Isbel, Nicole, Johnson, David W., Donnellan, Leigh, Deo, Permal, Akison, Lisa K., Moritz, Karen M. and O'Moore-Sullivan, Trisha (2021). Advanced glycation end products as predictors of renal function in youth with type 1 diabetes. Scientific Reports, 11 (1) 9422, 9422. doi: 10.1038/s41598-021-88786-4
2021
Journal Article
The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)
Zhuang, Aowen, Yap, Felicia Y. T., Borg, Danielle J., McCarthy, Domenica, Fotheringham, Amelia, Leung, Sherman, Penfold, Sally A., Sourris, Karly C., Coughlan, Melinda T., Schulz, Benjamin L. and Forbes, Josephine M. (2021). The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition). Endocrinology, Diabetes and Metabolism, 4 (3) e00278, e00278. doi: 10.1002/edm2.278
2020
Other Outputs
The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes
Leung, Sherman Shu-Yan (2020). The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/2383da0
2020
Journal Article
Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes
Le Bagge, Selena, Fotheringham, Amelia K., Leung, Sherman S. and Forbes, Josephine M. (2020). Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes. Medicinal Research Reviews, 40 (4) med.21654, 1200-1219. doi: 10.1002/med.21654
2016
Journal Article
Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis
Leung, Sherman S., Forbes, Josephine M. and Borg, Danielle J. (2016). Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis. Current Diabetes Reports, 16 (10) 100, 100. doi: 10.1007/s11892-016-0782-y
2015
Conference Publication
Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse
Leung, S. S.-Y., Borg, D. J., McCarthy, D., Zhuang, A., Fotheringham, A., Di Trapani, G., Groop, P.-H., Knip, M. and Forbes, J. (2015). Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse. Joint Annual Conference of the International Society for Pediatric and Adolescent Diabetes and Australasian Paediatric Endocrine Group (ISPAD+APEG 2015), Brisbane, QLD Australia, 7-10 October 2015. Hoboken, NJ USA: Wiley-Blackwell Publishing. doi: 10.1111/pedi.12309
2015
Conference Publication
Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes
Leung, Sherman S., Borg, Danielle J., Paul, Moumita, Sharland, Alexandra F. and Forbes, Josephine M. (2015). Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes. 9th Biennial Meeting of the Australasian-Gene-and-Cell-Therapy-Society (AGCTS), Parkville, VIC Australia, 29 April - 1 May 2015. Hoboken, NJ United States: Wiley-Blackwell.
2015
Conference Publication
Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model
Leung, Sherman, Borg, Danielle J., McCarthy, Domenica, Zhuang, Aowen, Forbes, Josephine and Ward, Micheal (2015). Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model. 75th Scientific Sessions of the American-Diabetes-Association, Boston, MA United States, 5-9 June 2015. Alexandria, VA United States: American Diabetes Association.
2015
Conference Publication
Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model
Borg, D. J., Leung, S., Zhuang, A., Fotheringham, A., McCarthy, D., Di Trapani, J., Groop, P. -H., Knip, M. and Forbes, J. (2015). Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model. 51st Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Stockholm, Sweden, 14-18 September 2015. Heidelberg, Germany: Springer. doi: 10.1007/s00125-015-3687-4
Funding
Past funding
Supervision
Availability
- Dr Sherman Leung is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
The receptor for advanced glycation end products and its role in Type 1 diabetes development
Associate Advisor
Other advisors: Dr Amelia Fotheringham, Professor Emma Hamilton-Williams, Dr Irina Buckle, Honorary Professor Josephine Forbes
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Doctor Philosophy
sRAGE as a preventative therapy for T1D and potential biomarker of pregnancy complications
Associate Advisor
Other advisors: Dr Amelia Fotheringham, Professor Emma Hamilton-Williams, Dr Irina Buckle, Honorary Professor Josephine Forbes
Media
Enquiries
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