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Dr Sherman Leung
Dr

Sherman Leung

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Overview

Background

Dr. Sherman Leung is the Head of Research Operations at Wesley Research Institute - the research partner of UnitingCare. UnitingCare is the largest private employer in Queensland, encompassing four hospitals (The Wesley Hospital, St. Andrew's War Memorial Hospital, Buderim Private Hospital and St. Stephen's Hospital), as well as significant community-based offerings through Lifeline, Blue Care, Family and Disability Services, and ARRCS.

Dr. Leung is a PhD trained scientist, conducting his research training at Mater Research Institute, The University of Queensland, during which his research was published in highly regarded peer-reviewed journals, including in 'Diabetes', receiving the Cover Image, an 'In This Issue' feature, and shared across the Australian-wide 7 Network news.

He has extensive experience in clinical trials, having worked at Microba Life Sciences, an ASX-listed biotechnology start-up, and Nucleus Network, Australia’s largest early phase clinical trial site having overseen the conduct of several high-profile COVID-19 projects including Nuvaxovid by Novavax that has been granted emergency authorisation in 40 countries including by the TGA, EMEA & FDA.

He contributes his spare time to the greater good through numerous initiatives in the industry including being a Board Director of the Australian Clinical Trials Alliance (ACTA), Editorial Board for 'Trials' – a BMC journal promoting all aspects of trials including methods, processes and non-significant outcomes for transparency in the field – being a former member of the Metro North Human Research Ethics Committee (HREC), and offering regular guest classrooms on clinical trials, informed consent and ethics at The University of Queensland.

Availability

Dr Sherman Leung is:
Not available for supervision

Works

Search Professor Sherman Leung’s works on UQ eSpace

12 works between 2015 and 2023

1 - 12 of 12 works

2023

Journal Article

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

Leung, Sherman S., Lenchik, Nataliya, Mathews, Clayton, Pugliese, Alberto, McCarthy, Domenica A., Le Bagge, Selena, Ewing, Adam, Harris, Mark, Radford, Kristen J., Borg, Danielle J., Gerling, Ivan and Forbes, Josephine M. (2023). Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Scientific Reports, 13 (1) 12948, 1-15. doi: 10.1038/s41598-023-39243-x

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

2022

Journal Article

Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells

Leung, Sherman S., Borg, Danielle J., McCarthy, Domenica A., Boursalian, Tamar E., Cracraft, Justen, Zhuang, Aowen, Fotheringham, Amelia K., Flemming, Nicole, Watkins, Thomas, Miles, John J., Groop, Per-Henrik, Scheijen, Jean L., Schalkwijk, Casper G., Steptoe, Raymond J., Radford, Kristen J., Knip, Mikael and Forbes, Josephine M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71 (9), 1994-2008. doi: 10.2337/db22-0177

Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells

2021

Journal Article

Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model

Borg, Danielle J., Faridi, Pouya, Giam, Kai Lin, Reeves, Peta, Fotheringham, Amelia K., McCarthy, Domenica A., Leung, Sherman, Ward, Micheal S., Harcourt, Brooke E., Ayala, Rochelle, Scheijen, Jean L., Briskey, David, Dudek, Nadine L., Schalkwijk, Casper G., Steptoe, Raymond, Purcell, Anthony W. and Forbes, Josephine M. (2021). Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model. Metabolites, 11 (7) 426, 1-21. doi: 10.3390/metabo11070426

Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model

2021

Journal Article

Advanced glycation end products as predictors of renal function in youth with type 1 diabetes

Forbes, Josephine M., Le Bagge, Selena, Righi, Samuel, Fotheringham, Amelia K., Gallo, Linda A., McCarthy, Domenica A., Leung, Sherman, Baskerville, Tracey, Nisbett, Janelle, Morton, Adam, Teasdale, Stephanie, D'Silva, Neisha, Barrett, Helen, Jones, Timothy, Couper, Jennifer, Donaghue, Kim, Isbel, Nicole, Johnson, David W., Donnellan, Leigh, Deo, Permal, Akison, Lisa K., Moritz, Karen M. and O'Moore-Sullivan, Trisha (2021). Advanced glycation end products as predictors of renal function in youth with type 1 diabetes. Scientific Reports, 11 (1) 9422, 9422. doi: 10.1038/s41598-021-88786-4

Advanced glycation end products as predictors of renal function in youth with type 1 diabetes

2021

Journal Article

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Zhuang, Aowen, Yap, Felicia Y. T., Borg, Danielle J., McCarthy, Domenica, Fotheringham, Amelia, Leung, Sherman, Penfold, Sally A., Sourris, Karly C., Coughlan, Melinda T., Schulz, Benjamin L. and Forbes, Josephine M. (2021). The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition). Endocrinology, Diabetes and Metabolism, 4 (3) e00278, e00278. doi: 10.1002/edm2.278

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

2020

Other Outputs

The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes

Leung, Sherman Shu-Yan (2020). The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/2383da0

The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes

2020

Journal Article

Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes

Le Bagge, Selena, Fotheringham, Amelia K., Leung, Sherman S. and Forbes, Josephine M. (2020). Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes. Medicinal Research Reviews, 40 (4) med.21654, 1200-1219. doi: 10.1002/med.21654

Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes

2016

Journal Article

Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis

Leung, Sherman S., Forbes, Josephine M. and Borg, Danielle J. (2016). Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis. Current Diabetes Reports, 16 (10) 100, 100. doi: 10.1007/s11892-016-0782-y

Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis

2015

Conference Publication

Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse

Leung, S. S.-Y., Borg, D. J., McCarthy, D., Zhuang, A., Fotheringham, A., Di Trapani, G., Groop, P.-H., Knip, M. and Forbes, J. (2015). Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse. Joint Annual Conference of the International Society for Pediatric and Adolescent Diabetes and Australasian Paediatric Endocrine Group (ISPAD+APEG 2015), Brisbane, QLD Australia, 7-10 October 2015. Hoboken, NJ USA: Wiley-Blackwell Publishing. doi: 10.1111/pedi.12309

Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse

2015

Conference Publication

Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes

Leung, Sherman S., Borg, Danielle J., Paul, Moumita, Sharland, Alexandra F. and Forbes, Josephine M. (2015). Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes. 9th Biennial Meeting of the Australasian-Gene-and-Cell-Therapy-Society (AGCTS), Parkville, VIC Australia, 29 April - 1 May 2015. Hoboken, NJ United States: Wiley-Blackwell.

Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes

2015

Conference Publication

Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model

Leung, Sherman, Borg, Danielle J., McCarthy, Domenica, Zhuang, Aowen, Forbes, Josephine and Ward, Micheal (2015). Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model. 75th Scientific Sessions of the American-Diabetes-Association, Boston, MA United States, 5-9 June 2015. Alexandria, VA United States: American Diabetes Association.

Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model

2015

Conference Publication

Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model

Borg, D. J., Leung, S., Zhuang, A., Fotheringham, A., McCarthy, D., Di Trapani, J., Groop, P. -H., Knip, M. and Forbes, J. (2015). Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model. 51st Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Stockholm, Sweden, 14-18 September 2015. Heidelberg, Germany: Springer. doi: 10.1007/s00125-015-3687-4

Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model

Funding

Past funding

  • 2016 - 2018
    Advanced Glycation in the development of T1D (Helmsley Charitable Trust - George Eisenbath nPOD award for team science) - Administered by the University of Miami
    University of Miami
    Open grant

Supervision

Availability

Dr Sherman Leung is:
Not available for supervision

Supervision history

Current supervision

Media

Enquiries

For media enquiries about Dr Sherman Leung's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au