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Dr Sherman Leung
Dr

Sherman Leung

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Overview

Background

Dr. Sherman Leung is the Head of Research Operations at Wesley Research Institute - the official research partner for UnitingCare encompassing the four UnitingCare hospitals in Queensland as well as Lifeline, Blue Care, and Family and Disability Services. He is a PhD trained scientist, conducting his research training at The University of Queensland.

His research is published in highly regarded peer-reviewed journals, including recently in 'Diabetes', receiving the Cover Image, an 'In This Issue' feature, and shared across the Australian-wide 7 Network news. He has extensive experience in clinical trials, having worked at Microba Life Sciences, an ASX-listed biotechnology start-up, and Nucleus Network, Australia’s largest early phase clinical trial site having overseen the conduct of several high-profile COVID-19 projects including that of Nuvaxovid by Novavax that is now authorised for use by the TGA, EMEA & FDA across many jurisdictions worldwide.

At Wesley Research Institute, he is responsible for the Clinical Trials Centre, Biobank, Research Office and all research programs across the health and medical sciences. He contributes his time to numerous initiatives in the industry including being on the Editorial Board for 'Trials', being a former member of the Metro North Human Research Ethics Committee (HREC), and classrooms on clinical trials, informed consent and ethics to medical and postgraduate students at The University of Queensland.

Availability

Dr Sherman Leung is:
Available for supervision

Works

Search Professor Sherman Leung’s works on UQ eSpace

11 works between 2015 and 2023

1 - 11 of 11 works

2023

Journal Article

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

Leung, Sherman S., Lenchik, Nataliya, Mathews, Clayton, Pugliese, Alberto, McCarthy, Domenica A., Le Bagge, Selena, Ewing, Adam, Harris, Mark, Radford, Kristen J., Borg, Danielle J., Gerling, Ivan and Forbes, Josephine M. (2023). Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Scientific Reports, 13 (1) 12948, 1-15. doi: 10.1038/s41598-023-39243-x

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

2022

Journal Article

Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells

Leung, Sherman S., Borg, Danielle J., McCarthy, Domenica A., Boursalian, Tamar E., Cracraft, Justen, Zhuang, Aowen, Fotheringham, Amelia K., Flemming, Nicole, Watkins, Thomas, Miles, John J., Groop, Per-Henrik, Scheijen, Jean L., Schalkwijk, Casper G., Steptoe, Raymond J., Radford, Kristen J., Knip, Mikael and Forbes, Josephine M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71 (9), 1994-2008. doi: 10.2337/db22-0177

Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells

2021

Journal Article

Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model

Borg, Danielle J., Faridi, Pouya, Giam, Kai Lin, Reeves, Peta, Fotheringham, Amelia K., McCarthy, Domenica A., Leung, Sherman, Ward, Micheal S., Harcourt, Brooke E., Ayala, Rochelle, Scheijen, Jean L., Briskey, David, Dudek, Nadine L., Schalkwijk, Casper G., Steptoe, Raymond, Purcell, Anthony W. and Forbes, Josephine M. (2021). Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model. Metabolites, 11 (7) 426, 1-21. doi: 10.3390/metabo11070426

Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model

2021

Journal Article

Advanced glycation end products as predictors of renal function in youth with type 1 diabetes

Forbes, Josephine M., Le Bagge, Selena, Righi, Samuel, Fotheringham, Amelia K., Gallo, Linda A., McCarthy, Domenica A., Leung, Sherman, Baskerville, Tracey, Nisbett, Janelle, Morton, Adam, Teasdale, Stephanie, D'Silva, Neisha, Barrett, Helen, Jones, Timothy, Couper, Jennifer, Donaghue, Kim, Isbel, Nicole, Johnson, David W., Donnellan, Leigh, Deo, Permal, Akison, Lisa K., Moritz, Karen M. and O'Moore-Sullivan, Trisha (2021). Advanced glycation end products as predictors of renal function in youth with type 1 diabetes. Scientific Reports, 11 (1) 9422, 9422. doi: 10.1038/s41598-021-88786-4

Advanced glycation end products as predictors of renal function in youth with type 1 diabetes

2021

Journal Article

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Zhuang, Aowen, Yap, Felicia Y. T., Borg, Danielle J., McCarthy, Domenica, Fotheringham, Amelia, Leung, Sherman, Penfold, Sally A., Sourris, Karly C., Coughlan, Melinda T., Schulz, Benjamin L. and Forbes, Josephine M. (2021). The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition). Endocrinology, Diabetes and Metabolism, 4 (3) e00278, e00278. doi: 10.1002/edm2.278

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

2020

Journal Article

Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes

Le Bagge, Selena, Fotheringham, Amelia K., Leung, Sherman S. and Forbes, Josephine M. (2020). Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes. Medicinal Research Reviews, 40 (4) med.21654, 1200-1219. doi: 10.1002/med.21654

Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes

2016

Journal Article

Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis

Leung, Sherman S., Forbes, Josephine M. and Borg, Danielle J. (2016). Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis. Current Diabetes Reports, 16 (10) 100, 100. doi: 10.1007/s11892-016-0782-y

Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis

2015

Conference Publication

Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse

Leung, S. S.-Y., Borg, D. J., McCarthy, D., Zhuang, A., Fotheringham, A., Di Trapani, G., Groop, P.-H., Knip, M. and Forbes, J. (2015). Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse. Joint Annual Conference of the International Society for Pediatric and Adolescent Diabetes and Australasian Paediatric Endocrine Group (ISPAD+APEG 2015), Brisbane, QLD Australia, 7-10 October 2015. Hoboken, NJ USA: Wiley-Blackwell Publishing. doi: 10.1111/pedi.12309

Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse

2015

Conference Publication

Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes

Leung, Sherman S., Borg, Danielle J., Paul, Moumita, Sharland, Alexandra F. and Forbes, Josephine M. (2015). Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes. 9th Biennial Meeting of the Australasian-Gene-and-Cell-Therapy-Society (AGCTS), Parkville, VIC Australia, 29 April - 1 May 2015. Hoboken, NJ United States: Wiley-Blackwell.

Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes

2015

Conference Publication

Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model

Leung, Sherman, Borg, Danielle J., McCarthy, Domenica, Zhuang, Aowen, Forbes, Josephine and Ward, Micheal (2015). Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model. 75th Scientific Sessions of the American-Diabetes-Association, Boston, MA USA, 5-9 June 2015. Alexandria, VA USA: American Diabetes Association.

Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model

2015

Conference Publication

Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model

Borg, D. J., Leung, S., Zhuang, A., Fotheringham, A., McCarthy, D., Di Trapani, J., Groop, P. -H., Knip, M. and Forbes, J. (2015). Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model. 51st Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Stockholm, Sweden, 14-18 September 2015. Heidelberg, Germany: Springer. doi: 10.1007/s00125-015-3687-4

Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model

Funding

Past funding

  • 2016 - 2018
    Advanced Glycation in the development of T1D (Helmsley Charitable Trust - George Eisenbath nPOD award for team science) - Administered by the University of Miami
    University of Miami
    Open grant

Supervision

Availability

Dr Sherman Leung is:
Available for supervision

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Supervision history

Current supervision

Media

Enquiries

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