Overview
Availability
- Dr Irina Buckle is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Research interests
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Immunology, Autoimmunity, Type 1 Diabetes, Immunotherapy, Humanised Mouse Models, Multi-parameter Flow Cytometry
Works
Search Professor Irina Buckle’s works on UQ eSpace
2024
Journal Article
Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis
Tu, Cui, Buckle, Irina, Leal Rojas, Ingrid, Rossi, Gustavo Rodrigues, Sester, David P, Moore, Andrew S, Radford, Kristen, Guillerey, Camille and Souza‐Fonseca‐Guimaraes, Fernando (2024). Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis. Clinical & Translational Immunology, 13 (3) e1501, e1501. doi: 10.1002/cti2.1501
2023
Conference Publication
Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial dna profiles
Sullivan, Mitchell, Pham, Uyen, McCarthy, Domenica, Flemming, Nicole, Fotheringham, Amelia, Chandrashekar, Preeti, Whiddett, Rani, Buckle, Irina, Summers, Kim, Hodson, Mark, de Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasedale, Stephanie, Doomun, Sheik, de Souza, David, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Coughlan, Melinda, Johnson, David, O'Moore-Sullivan, Trisha, Barret, Helen, Marcovecchio, M. Loredana, Donaghue, Kim and Forbes, Josephine (2023). Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial dna profiles. 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4-6 September 2023. Richmond, VIC Australia: John Wiley & Sons.
2023
Journal Article
High dimensional analysis reveals distinct NK cell subsets but conserved response to stimulation in umbilical cord blood and adult peripheral blood
Buckle, Irina, Johnson, Anthony, Rojas, Ingrid Leal, Weinert, Vicky, Sester, David P., Radford, Kristen and Guillerey, Camille (2023). High dimensional analysis reveals distinct NK cell subsets but conserved response to stimulation in umbilical cord blood and adult peripheral blood. European Journal of Immunology, 53 (6) 2250118, 1-13. doi: 10.1002/eji.202250118
2022
Book Chapter
The role of the receptor for advanced glycation endproducts (RAGE) in type 1 diabetes: an immune cell perspective
Buckle, Irina and Forbes, Josephine M. (2022). The role of the receptor for advanced glycation endproducts (RAGE) in type 1 diabetes: an immune cell perspective. Type 1 diabetes in 2023 - from real practice to open questions. (pp. 1-20) edited by Rudolf Chlup. London, United Kingdom: IntechOpen. doi: 10.5772/intechopen.108528
2022
Journal Article
Advanced glycation end products and inflammation in type 1 diabetes development
Du, Chenping, Whiddett, Rani O., Buckle, Irina, Chen, Chen, Forbes, Josephine M. and Fotheringham, Amelia K. (2022). Advanced glycation end products and inflammation in type 1 diabetes development. Cells, 11 (21) 3503, 1-18. doi: 10.3390/cells11213503
2022
Journal Article
Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope
Buckle, Irina, Loaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Zhang, Vivian, Talekar, Meghna, Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2022). Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope. Immunology and Cell Biology, 100 (1), 33-48. doi: 10.1111/imcb.12506
2021
Journal Article
Inhibitory receptors and immune checkpoints regulating natural killer cell responses to cancer
Buckle, Irina and Guillerey, Camille (2021). Inhibitory receptors and immune checkpoints regulating natural killer cell responses to cancer. Cancers, 13 (17) 4263, 4263. doi: 10.3390/cancers13174263
2020
Journal Article
A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 Diabetes
Loaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Buckle, Irina and Hamilton-Williams, Emma E. (2020). A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 Diabetes. Current Diabetes Reports, 20 (12) 70, 70. doi: 10.1007/s11892-020-01363-3
2020
Journal Article
Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetes
Bergot, Anne-Sophie, Buckle, Irina, Cikaluru, Sumana, Naranjo, Jennifer Loaiza, Wright, Casey Maree, Zheng, Guoliang, Talekar, Meghna, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2020). Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetes. Journal of Immunology, 204 (7), ji1901128-1797. doi: 10.4049/jimmunol.1901128
2019
Other Outputs
Antigen-specific peptide immunotherapy for treatment and prevention of type 1 diabetes
Buckle, Irina (2019). Antigen-specific peptide immunotherapy for treatment and prevention of type 1 diabetes. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2019.562
2016
Journal Article
Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice
James, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7
2016
Conference Publication
Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice
Buckle, I, Steptoe, R. J., Thomas, R. and Hamilton-Williams, E. E. (2016). Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.
Funding
Current funding
Supervision
Availability
- Dr Irina Buckle is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The Characterisation of Immune Cells in Response To RAGE Antagonism Therapy in Mouse Models of Type 1 Diabetes
Principal Advisor
Other advisors: Professor Benjamin Schulz, Dr Amelia Fotheringham, Honorary Professor Josephine Forbes
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Doctor Philosophy
The receptor for advanced glycation end products and its role in Type 1 diabetes development
Associate Advisor
Other advisors: Dr Amelia Fotheringham, Associate Professor Emma Hamilton-Williams, Dr Sherman Leung, Honorary Professor Josephine Forbes
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Doctor Philosophy
Early mitochondrial dysfunction in diabetic kidney
Associate Advisor
Other advisors: Dr Amelia Fotheringham, Honorary Professor Josephine Forbes
Media
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