Overview
Availability
- Honorary Professor Josephine Forbes is:
- Available for supervision
Qualifications
- Bachelor, University of Melbourne
- Doctor of Philosophy, University of Melbourne
Works
Search Professor Josephine Forbes’s works on UQ eSpace
2024
Journal Article
Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation
Sourris, Karly C., Ding, Yi, Maxwell, Scott S., Al-sharea, Annas, Kantharidis, Phillip, Mohan, Muthukumar, Rosado, Carlos J., Penfold, Sally A., Haase, Claus, Xu, Yangsong, Forbes, Josephine M., Crawford, Simon, Ramm, Georg, Harcourt, Brooke E., Jandeleit-Dahm, Karin, Advani, Andrew, Murphy, Andrew J., Timmermann, Daniel B., Karihaloo, Anil, Knudsen, Lotte Bjerre, El-Osta, Assam, Drucker, Daniel J., Cooper, Mark E. and Coughlan, Melinda T. (2024). Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation. Kidney International, 105 (1), 132-149. doi: 10.1016/j.kint.2023.09.029
2023
Journal Article
Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes
Leung, Sherman S., Lenchik, Nataliya, Mathews, Clayton, Pugliese, Alberto, McCarthy, Domenica A., Le Bagge, Selena, Ewing, Adam, Harris, Mark, Radford, Kristen J., Borg, Danielle J., Gerling, Ivan and Forbes, Josephine M. (2023). Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Scientific Reports, 13 (1) 12948, 1-15. doi: 10.1038/s41598-023-39243-x
2023
Conference Publication
Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial dna profiles
Sullivan, Mitchell, Pham, Uyen, McCarthy, Domenica, Flemming, Nicole, Fotheringham, Amelia, Chandrashekar, Preeti, Whiddett, Rani, Buckle, Irina, Summers, Kim, Hodson, Mark, de Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasedale, Stephanie, Doomun, Sheik, de Souza, David, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Coughlan, Melinda, Johnson, David, O'Moore-Sullivan, Trisha, Barret, Helen, Marcovecchio, M. Loredana, Donaghue, Kim and Forbes, Josephine (2023). Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial dna profiles. 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4-6 September 2023. Richmond, VIC Australia: John Wiley & Sons.
2023
Conference Publication
Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC)
Kassianos, Andrew J., Giuliani, Kurt, Nag, Purba, Hong, Seokchan, Wang, Xiangju, Johnston, Rebecca L., Adams, Benjamin, Grivei, Anca, Ho, Kenneth, Ng, Monica, Waddell, Nicola, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2023). Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC). 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4-6 September 2023. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14216
2022
Journal Article
RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice
Joshi, Aditi A., Wu, Ying, Deng, Songyan, Preston-Hurlburt, Paula, Forbes, Josephine M. and Herold, Kevan C. (2022). RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice. Clinical Immunology, 245 109165, 1-6. doi: 10.1016/j.clim.2022.109165
2022
Book Chapter
The role of the receptor for advanced glycation endproducts (RAGE) in type 1 diabetes: an immune cell perspective
Buckle, Irina and Forbes, Josephine M. (2022). The role of the receptor for advanced glycation endproducts (RAGE) in type 1 diabetes: an immune cell perspective. Type 1 diabetes in 2023 - from real practice to open questions. (pp. 1-20) edited by Rudolf Chlup. London, United Kingdom: IntechOpen. doi: 10.5772/intechopen.108528
2022
Journal Article
Advanced glycation end products and inflammation in type 1 diabetes development
Du, Chenping, Whiddett, Rani O., Buckle, Irina, Chen, Chen, Forbes, Josephine M. and Fotheringham, Amelia K. (2022). Advanced glycation end products and inflammation in type 1 diabetes development. Cells, 11 (21) 3503, 1-18. doi: 10.3390/cells11213503
2022
Conference Publication
Mitochondrial dysfunction aligns with risk for diabetic kidney disease in youth with type 1 diabetes
Sullivan, Mitchell, McCarthy, Domenica, Flemming, Nicole, Chandrashekar, Preeti, Hodson, Mark, Fotheringham, Amelia, Whiddett, Rani, De Silva, Neisha, Nisbet, Jinelle, Morton, Adam, Teasdale, Stephanie, Isbel, Nicole, Jones, Timothy, Couper, Jennier, Thorburn, David, Johnson, David, Cotterill, Andrew, Barrett, Helen, O'Moore-Sullivan, Trisha, Donaghue, Kim and Forbes, Josephine (2022). Mitochondrial dysfunction aligns with risk for diabetic kidney disease in youth with type 1 diabetes. 57th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, NSW, Australia, 17–19 October 2022. Richmond, VIC, Australia: John Wiley & Sons.
2022
Journal Article
Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells
Giuliani, Kurt T. K., Grivei, Anca, Nag, Purba, Wang, Xiangju, Rist, Melissa, Kildey, Katrina, Law, Becker, Ng, Monica S., Wilkinson, Ray, Ungerer, Jacobus, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2022). Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells. Cell Death and Disease, 13 (8) 739, 1-13. doi: 10.1038/s41419-022-05191-z
2022
Journal Article
Mitochondrial dysfunction in individuals with diabetic kidney disease: a systematic review
Flemming, Nicole, Pernoud, Laura, Forbes, Josephine and Gallo, Linda (2022). Mitochondrial dysfunction in individuals with diabetic kidney disease: a systematic review. Cells, 11 (16) 2481, 1-24. doi: 10.3390/cells11162481
2022
Journal Article
Advanced glycation end products (AGEs) and chronic kidney disease: does the modern diet AGE the kidney?
Fotheringham, Amelia K., Gallo, Linda A., Borg, Danielle J. and Forbes, Josephine M. (2022). Advanced glycation end products (AGEs) and chronic kidney disease: does the modern diet AGE the kidney?. Nutrients, 14 (13) 2675, 1-28. doi: 10.3390/nu14132675
2022
Journal Article
Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells
Leung, Sherman S., Borg, Danielle J., McCarthy, Domenica A., Boursalian, Tamar E., Cracraft, Justen, Zhuang, Aowen, Fotheringham, Amelia K., Flemming, Nicole, Watkins, Thomas, Miles, John J., Groop, Per-Henrik, Scheijen, Jean L., Schalkwijk, Casper G., Steptoe, Raymond J., Radford, Kristen J., Knip, Mikael and Forbes, Josephine M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71 (9), 1994-2008. doi: 10.2337/db22-0177
2022
Journal Article
The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: a nested mechanistic sub-study
Doola, Ra'eesa, Deane, Adam M., Barrett, Helen L., Okano, Satomi, Tolcher, Debbie M., Gregory, Kye, Coombes, Jeff S., Schalkwijk, Casper, Todd, Alwyn S., Forbes, Josephine M. and Sturgess, David J. (2022). The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: a nested mechanistic sub-study. Journal of Human Nutrition and Dietetics, 35 (3), 455-465. doi: 10.1111/jhn.12959
2021
Journal Article
Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure
Fotheringham, Amelia K., Solon-Biet, Samantha M., Bielefeldt-Ohmann, Helle, McCarthy, Domenica A., McMahon, Aisling C., Ruohonen, Kari, Li, Isaac, Sullivan, Mitchell A., Whiddett, Rani O., Borg, Danielle J., Cogger, Victoria C., Ballard, William O., Turner, Nigel, Melvin, Richard G., Raubenheimer, David, Le Couteur, David G., Simpson, Stephen J. and Forbes, Josephine M. (2021). Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure. iScience, 24 (11) 103308, 103308. doi: 10.1016/j.isci.2021.103308
2021
Journal Article
T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes
Forbes, Josephine M., McCarthy, Domenica A., Kassianos, Andrew J., Baskerville, Tracey, Fotheringham, Amelia J., Giuliani, Kurt T. K., Grivei, Anca, Murphy, Andrew J., Flynn, Michelle C., Sullivan, Mitchell A., Chandrashekar, Preeti, Whiddett, Rani, Radford, Kristen J., Flemming, Nicole, Beard, Sam S., D’Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasdale, Stephanie, Russell, Anthony, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Healy, Helen, Harris, Mark, Donaghue, Kim, Johnson, David W., Cotterill, Andrew, Barrett, Helen L. and O’Moore-Sullivan, Trisha (2021). T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes. Diabetes, 70 (8), 1754-1766. doi: 10.2337/db20-1081
2021
Journal Article
Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model
Borg, Danielle J., Faridi, Pouya, Giam, Kai Lin, Reeves, Peta, Fotheringham, Amelia K., McCarthy, Domenica A., Leung, Sherman, Ward, Micheal S., Harcourt, Brooke E., Ayala, Rochelle, Scheijen, Jean L., Briskey, David, Dudek, Nadine L., Schalkwijk, Casper G., Steptoe, Raymond, Purcell, Anthony W. and Forbes, Josephine M. (2021). Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model. Metabolites, 11 (7) 426, 1-21. doi: 10.3390/metabo11070426
2021
Journal Article
Advanced glycation end products as predictors of renal function in youth with type 1 diabetes
Forbes, Josephine M., Le Bagge, Selena, Righi, Samuel, Fotheringham, Amelia K., Gallo, Linda A., McCarthy, Domenica A., Leung, Sherman, Baskerville, Tracey, Nisbett, Janelle, Morton, Adam, Teasdale, Stephanie, D'Silva, Neisha, Barrett, Helen, Jones, Timothy, Couper, Jennifer, Donaghue, Kim, Isbel, Nicole, Johnson, David W., Donnellan, Leigh, Deo, Permal, Akison, Lisa K., Moritz, Karen M. and O'Moore-Sullivan, Trisha (2021). Advanced glycation end products as predictors of renal function in youth with type 1 diabetes. Scientific Reports, 11 (1) 9422, 9422. doi: 10.1038/s41598-021-88786-4
2021
Journal Article
Long term high protein diet feeding alters the microbiome and increases intestinal permeability, systemic inflammation and kidney injury in mice
Snelson, Matthew, Clarke, Rachel Elise, Nguyen, Tuong-Vi, Penfold, Sally Anne, Forbes, Josephine Maree, Tan, Sih Min and Coughlan, Melinda Therese (2021). Long term high protein diet feeding alters the microbiome and increases intestinal permeability, systemic inflammation and kidney injury in mice. Molecular Nutrition and Food Research, 65 (8) 2000851, 1-12. doi: 10.1002/mnfr.202000851
2021
Journal Article
Processed foods drive intestinal barrier permeability and microvascular diseases
Snelson, Matthew, Tan, Sih Min, Clarke, Rachel E., De Pasquale, Cassandra, Thallas-Bonke, Vicki, Nguyen, Tuong-Vi, Penfold, Sally A., Harcourt, Brooke E., Sourris, Karly C., Lindblom, Runa S., Ziemann, Mark, Steer, David, El-Osta, Assam, Davies, Michael J., Donnellan, Leigh, Deo, Permal, Kellow, Nicole J., Cooper, Mark E., Woodruff, Trent M., Mackay, Charles R., Forbes, Josephine M. and Coughlan, Melinda T. (2021). Processed foods drive intestinal barrier permeability and microvascular diseases. Science Advances, 7 (14) eabe4841, 1-16. doi: 10.1126/sciadv.abe4841
2021
Journal Article
Impact of dietary carbohydrate type and protein–carbohydrate interaction on metabolic health
Wali, Jibran A., Milner, Annabelle J., Luk, Alison W. S., Pulpitel, Tamara J., Dodgson, Tim, Facey, Harrison J. W., Wahl, Devin, Kebede, Melkam A., Senior, Alistair M., Sullivan, Mitchell A., Brandon, Amanda E., Yau, Belinda, Lockwood, Glen P., Koay, Yen Chin, Ribeiro, Rosilene, Solon-Biet, Samantha M., Bell-Anderson, Kim S., O’Sullivan, John F., Macia, Laurence, Forbes, Josephine M., Cooney, Gregory J., Cogger, Victoria C., Holmes, Andrew, Raubenheimer, David, Le Couteur, David G. and Simpson, Stephen J. (2021). Impact of dietary carbohydrate type and protein–carbohydrate interaction on metabolic health. Nature Metabolism, 3 (6), 810-828. doi: 10.1038/s42255-021-00393-9
Funding
Current funding
Supervision
Availability
- Honorary Professor Josephine Forbes is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
New insights into molecular pathways involved in the development of diabetic kidney disease: Towards earlier disease detection and identification of novel therapeutic targets
Principal Advisor
Other advisors: Associate Professor Ross Francis
-
Doctor Philosophy
Early mitochondrial dysfunction in diabetic kidney
Principal Advisor
Other advisors: Dr Amelia Fotheringham, Dr Irina Buckle
-
Doctor Philosophy
The receptor for advanced glycation end products and its role in Type 1 diabetes development
Principal Advisor
Other advisors: Dr Amelia Fotheringham, Associate Professor Emma Hamilton-Williams, Dr Irina Buckle, Dr Sherman Leung
-
Doctor Philosophy
Unravelling the role of abnormal glycogen accumulation in diabetic kidney disease
Associate Advisor
Other advisors: Dr Mitchell Sullivan
-
Doctor Philosophy
The Characterisation of Immune Cells in Response To RAGE Antagonism Therapy in Mouse Models of Type 1 Diabetes
Associate Advisor
Other advisors: Professor Benjamin Schulz, Dr Amelia Fotheringham, Dr Irina Buckle
Completed supervision
-
2021
Doctor Philosophy
Mitochondrial dysfunction as a pathological mediator in diabetic kidney disease
Principal Advisor
Other advisors: Dr Linda Gallo
-
2020
Doctor Philosophy
The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes
Principal Advisor
Other advisors: Honorary Professor Kristen Radford
-
2020
Doctor Philosophy
Novel dietary factors in diabetic and non-diabetic kidney disease
Principal Advisor
-
2018
Doctor Philosophy
Novel role of AGE-R1/OST48 in the metabolome and proteome promoting ER stress in the kidney and liver
Principal Advisor
Other advisors: Professor Benjamin Schulz, Dr Linda Gallo
-
2023
Doctor Philosophy
Kidneys on fire: The role of inflammasome signalling in human chronic kidney disease
Associate Advisor
Other advisors: Dr Andrew Kassianos
-
2019
Doctor Philosophy
Nutritional management of hyperglycaemia in intensive care medicine
Associate Advisor
Other advisors: Associate Professor David Sturgess
Media
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