Overview
Background
Dominic Guanzon is a research fellow at the University of Queensland within the Salomon Lab, and supported by the Lions Medical Research Foundation. His expertise lies in the fascinating realm of extracellular vesicles where he is the genomics leader. Dominic’s research involves developing nucleic acid blood tests to diagnose disease. His primary research focus is on predicting chemotherapy response in women diagnosed with ovarian cancer, specifically distinguishing between individuals who respond positively to chemotherapy and those resistant to it (chemoresistance).
Availability
- Dr Dominic Guanzon is:
- Available for supervision
Works
Search Professor Dominic Guanzon’s works on UQ eSpace
2019
Conference Publication
Exosomal MiRNA profile in exosomes isolated from adipose tissue explants from normal and gestational diabetes mellitus pregnancies
Jayabalan, Nanthini, Guanzon, Dominic, McIntyre, David, Lappas, Martha and Salomon, Carlos (2019). Exosomal MiRNA profile in exosomes isolated from adipose tissue explants from normal and gestational diabetes mellitus pregnancies. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI) , Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.
2019
Journal Article
Quantitative proteomics by SWATH-MS suggest an association between circulating exosomes and maternal metabolic changes in gestational diabetes mellitus
Jayabalan, Nanthini, Lai, Andrew, Nair, Soumyalekshmi, Guanzon, Dominic, Scholz-Romero, Katherin, Palma, Carlos, McIntyre, Harold David, Lappas, Martha and Salomon, Carlos (2019). Quantitative proteomics by SWATH-MS suggest an association between circulating exosomes and maternal metabolic changes in gestational diabetes mellitus. Proteomics, 19 (1-2) 1800164, e1800164. doi: 10.1002/pmic.201800164
2019
Conference Publication
Exosomal protein and miRNA analysis in cervico-vaginal fluid at early gestation from term and preterm pregnancies
Tribe, Rachel M., Jenkins, Holly, Palma, Carlos, Lai, Andrew, Guanzon, Dominic, Hezelgrave, Natasha L., Shennan, Andrew H. and Salomon, Carlos (2019). Exosomal protein and miRNA analysis in cervico-vaginal fluid at early gestation from term and preterm pregnancies. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12 - 16 March 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079
2019
Conference Publication
Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression
Sharma, Shayna, Lai, Andrew, Guanzon, Dominic, Morgan, Terry, Perrin, Lewis C., Hooper, John D. and Salomon, Carlos (2019). Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079
2018
Journal Article
Adipose tissue exosomal proteomic profile reveals a role on placenta glucose metabolism in gestational diabetes mellitus
Jayabalan, Nanthini, Lai, Andrew, Ormazabal, Valeska, Adam, Stefanie, Guanzon, Dominic, Palma, Carlos, Scholz-Romero, Katherin, Lim, Ratana, Jansson, Thomas, McIntyre, Harold David, Lappas, Martha and Salomon, Carlos (2018). Adipose tissue exosomal proteomic profile reveals a role on placenta glucose metabolism in gestational diabetes mellitus. The Journal of Clinical Endocrinology & Metabolism, 104 (5) jcem-201801599, 1735-1752. doi: 10.1210/jc.2018-01599
2018
Journal Article
The potential role of miRNAs and exosomes in chemotherapy in ovarian cancer
Alharbi, Mona, Zuñiga, Felipe, Elfeky, Omar, Guanzon, Dominic, Lai, Andrew, Rice, Gregory E., Perrin, Lewis, Hooper, John and Salomon, Carlos (2018). The potential role of miRNAs and exosomes in chemotherapy in ovarian cancer. Endocrine-Related Cancer, 25 (12), R663-R685. doi: 10.1530/erc-18-0019
2018
Journal Article
Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity
Nair, Soumyalekshmi, Jayabalan, Nanthini, Guanzon, Dominic, Palma, Carlos, Scholz-Romero, Katherin, Elfeky, Omar, Zuñiga, Felipe, Ormazabal, Valeska, Diaz, Emilio, Rice, Gregory E., Duncombe, Gregory, Jansson, Thomas, McIntyre, Harold David, Lappas, Martha and Salomon, Carlos (2018). Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity. Clinical Science, 132 (22), 2451-2467. doi: 10.1042/cs20180487
2018
Journal Article
Circulating exosomal miRNA profile during term and preterm birth pregnancies - a longitudinal study
Menon, Ramkumar, Debnath, Chirantan, Lai, Andrew, Guanzon, Dominic, Bhatnagar, Shinjini, Pallavi, S. K., Sheller-Miller, Samantha, The Garbhini Study team and Salomon, Carlos (2018). Circulating exosomal miRNA profile during term and preterm birth pregnancies - a longitudinal study. Endocrinology, 160 (2), 249-275. doi: 10.1210/en.2018-00836
2018
Journal Article
Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large b-cell lymphoma
Cui, Qingyan, Vari, Frank, Cristino, Alexandre S., Salomon, Carlos, Rice, Gregory E., Sabdia, Muhammed B., Guanzon, Dominic, Palma, Carlos, Mathew, Marina, Talaulikar, Dipti, Jain, Sanjiv, Han, Erica, Hertzberg, Mark S., Gould, Clare, Crooks, Pauline, Thillaiyampalam, Gayathri, Keane, Colm and Gandhi, Maher K. (2018). Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large b-cell lymphoma. Oncotarget, 9 (78), 34644-34657. doi: 10.18632/oncotarget.26141
2018
Journal Article
Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migration
Sharma, Shayna, Alharbi, Mona, Kobayashi, Miharu, Lai, Andrew, Guanzon, Dominic, Zuñiga, Felipe, Ormazabal, Valeska, Palma, Carlos, Scholz-Romero, Katherin, Rice, Gregory E., Hooper, John D. and Salomon, Carlos (2018). Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migration. Clinical Science, 132 (18), 2029-2044. doi: 10.1042/CS20180425
2018
Journal Article
Differential expression of keratinocyte-derived extracellular vesicle mirnas discriminate exosomes from apoptotic bodies and microvesicles
Than, Uyen T. T., Guanzon, Dominic, Broadbent, James A., Leavesley, David, Salomon, Carlos and Parker, Tony J. (2018). Differential expression of keratinocyte-derived extracellular vesicle mirnas discriminate exosomes from apoptotic bodies and microvesicles. Frontiers in Endocrinology, 9 (SEP) 535, 1-15. doi: 10.3389/fendo.2018.00535
2018
Journal Article
Amniotic fluid exosome proteomic profile exhibits unique pathways of term and preterm labor
Dixon, C. Luke, Sheller-Miller, Samantha, Saade, George R., Fortunato, Stephen J., Lai, Andrew, Palma, Carlos, Guazon, Dominic, Salomon, Carlos and Menon, Ramkumar (2018). Amniotic fluid exosome proteomic profile exhibits unique pathways of term and preterm labor. Endocrinology, 159 (5), 2229-2240. doi: 10.1210/en.2018-00073
2018
Conference Publication
Interactions between placental exosomes and skeletal muscle implication in cell metabolism in gestational diabetes mellitus
Nair, Soumyalekshmi, Jayabalan, Nanthini, Guanzon, Dominic, Lai, Andrew, Scholz-Romero, Katherin, Elfeky, Omar, Zuniga, Felipe, Diaz, Emilio, McIntyre, David, Rice, Gregory E., Lappas, Martha and Salomon, Carlos (2018). Interactions between placental exosomes and skeletal muscle implication in cell metabolism in gestational diabetes mellitus. 65th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), San Diego, CA, United States, 6-10 March 2018. Thousand Oaks, CA, United States: Sage. doi: 10.1177/1933719118759999
2018
Conference Publication
Profiling of exosomes from amnion cells exposed to infection and oxidative stress reveal pathways of adverse pregnancy outcomes
Dixon, Christopher L., Kinhal, Vyjayanthi, Urrabaz-Garza, Rheanna, Guanzon, Dominic, Salomon, Carlos and Menon, Ramkumar (2018). Profiling of exosomes from amnion cells exposed to infection and oxidative stress reveal pathways of adverse pregnancy outcomes. 38th Annual Meeting and Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine, Dallas, TX United States, 29 January - 3 February 2018. New York, NY United States: Elsevier.
2018
Conference Publication
Integrative Analysis of Multi-Omics Exosomal Data for Identifying Multi-Markers for Susceptibility to Chemotherapy in Ovarian Cancer
Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Sharma, Shayna, Palma, Carlos, Zuniga, Felipe, Rice, Gregory E., Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2018). Integrative Analysis of Multi-Omics Exosomal Data for Identifying Multi-Markers for Susceptibility to Chemotherapy in Ovarian Cancer. 65th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), San Diego Ca United States, 6-10 March 2018. Thousand Oaks, CA United States: Sage.
2017
Journal Article
Placental Exosomes as Early Biomarker of Preeclampsia: Potential Role of Exosomal MicroRNAs Across Gestation
Salomon, Carlos, Guanzon, Dominic, Scholz-Romero, Katherin, Longo, Sherri, Correa, Paula, Illanes, Sebastian E. and Rice, Gregory E. (2017). Placental Exosomes as Early Biomarker of Preeclampsia: Potential Role of Exosomal MicroRNAs Across Gestation. Journal of Clinical Endocrinology & Metabolism, 102 (9), 3182-3194. doi: 10.1210/jc.2017-00672
2017
Journal Article
Bio-compartmentalization of microRNAs in exosomes during gestational diabetes mellitus
Iljas, Juvita D., Guanzon, Dominic, Elfeky, Omar, Rice, Gregory E. and Salomon, Carlos (2017). Bio-compartmentalization of microRNAs in exosomes during gestational diabetes mellitus. Placenta, 54, 76-82. doi: 10.1016/j.placenta.2016.12.002
2017
Journal Article
Association of Extracellular Membrane Vesicles with Cutaneous Wound Healing
Than, Uyen Thi Trang, Guanzon, Dominic, Leavesley, David and Parker, Tony (2017). Association of Extracellular Membrane Vesicles with Cutaneous Wound Healing. International Journal of Molecular Sciences, 18 (5) 956, 1-20. doi: 10.3390/ijms18050956
2017
Journal Article
Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells-liquid biopsies for monitoring complications of pregnancy
Truong, Grace, Guanzon, Dominic, Kinhal, Vyjayanthi, Elfeky, Omar, Lai, Andrew, Longo, Sherri, Nuzhat, Zarin, Palma, Carlos, Scholz-Romero, Katherin, Menon, Ramkumar, Mol, Ben W., Rice, Gregory E. and Salomon, Carlos (2017). Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells-liquid biopsies for monitoring complications of pregnancy. PLoS ONE, 12 (3) e0174514, e0174514. doi: 10.1371/journal.pone.0174514
2017
Conference Publication
Exosomal content in the plasma of patients with ovarian cancer reflect tumor state and induce the epithelial to mesenchymal transition in target cells
Sharma, Shayna, Scholz-Romero, Katherin, Kline, Richard, Wade, Katrina, Estes, Jacob, Palma, Carlos, Guanzon, Dominic, Lai, Andrew, Hooper, John, Rice, Gregory E. and Salomon, Carlos (2017). Exosomal content in the plasma of patients with ovarian cancer reflect tumor state and induce the epithelial to mesenchymal transition in target cells. 64th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Orlando, FL, United States, 15-18 March 2017. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719117699773
Funding
Current funding
Supervision
Availability
- Dr Dominic Guanzon is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Characterisation of EV-associated lipids in the progression of ovarian cancer
Associate Advisor
Other advisors: Honorary Professor John Hooper, Professor Carlos Salomon Gallo, Dr Andrew Lai
Media
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