Overview
Background
He is a Research Fellow with the Microbial Biology and Metagenomics group within the Immunology Program of the University of Queensland Frazer Institute and an honorary fellowship with The Commonwealth Scientific and Industrial Research Organisation (CSIRO, 2019-2021). His PhD research involved designing and applying DNA transfer systems for heterologous protein expression in Lactobacillus spp. He moved to The Ohio State University, USA to conduct postdoctoral research in gut microbiology, focusing on fibre-degrading bacteria and their production of multi-protein complexes supporting this process. He was recruited to join CSIRO (Brisbane) to undertake collaborative research projects for the “Colorectal Cancer and Gut Health” Theme of their Preventative Health Flagship Research Program. His contributions during this time were to develop further and use the DNA microarray technology he had pioneered to examine the stool and mucosa-associated microbiota communities in Crohn’s disease with French and Australian collaborators. These efforts led to several highly cited and high-impact publications in key medical journals, recognised for providing some of the first insights into the critical bacterial taxa that underpin the microbial “dysbiosis” now considered a hallmark of Crohn’s disease. In early 2019, he accepted a position with professor Morrison’s group as part of my ongoing collaborations with Melbourne University in Crohn’s disease research supported via the Helmsley Charitable Trust. He is providing leadership in using a novel ex-vivo combination of gut microbe culture and metagenomic sequencing for the first deep functional characterisation of the Crohn’s disease mucosa-associated microbiota. His development and implementation of innovative molecular biology and “omics” approach help better understand complex microbial gut systems relevant to human health.
Availability
- Dr Seungha Kang is:
- Available for supervision
Qualifications
- Doctor of Philosophy, Seoul National University
Works
Search Professor Seungha Kang’s works on UQ eSpace
2024
Journal Article
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?
Lim, Yenkai, Kang, Seungha, Shah, Ayesha, Holtmann, Gerald and Morrison, Mark (2024). Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?. Gut gutjnl-2024-334069, gutjnl-2024. doi: 10.1136/gutjnl-2024-334069
2024
Journal Article
The biogeography of the mucosa-associated microbiome in health and disease
Sternes, Peter R., Shah, Ayesha, Ayala Pintos, Camila, Fairlie, Thomas, Koloski, Natasha, Kang, Seungha, Tousignant, Kaylyn D., McIlroy, Simon J., Morrison, Mark, Tyson, Gene W. and Holtmann, Gerald J. (2024). The biogeography of the mucosa-associated microbiome in health and disease. Frontiers in Microbiology, 15 1454910, 1-14. doi: 10.3389/fmicb.2024.1454910
2024
Conference Publication
The biogeography of the mucosa-associated microbiota is associated with the presence and symptom severity of inflammatory bowel disease, proton pump inhibitor usage, and visceral sensitivity
Sternes, Peter, Shah, Ayesha, Pintos, Camila Ayela, Fairlie, Thomas, Koloski, Natasha, Kang, Seungha, Mcilroy, Simon, Morrison, Mark, Tyson, Gene and Holtmann, Gerald (2024). The biogeography of the mucosa-associated microbiota is associated with the presence and symptom severity of inflammatory bowel disease, proton pump inhibitor usage, and visceral sensitivity. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.
2024
Conference Publication
The Role Of Proteus Mirabilis And Its Derived Metabolite Cadaverine In Altering Bacterial Composition And Metabolite Profile In Crohn's Disease
Zhang, Jingwan, Sun, Qianru, Hao, Fangjia, Teh, Jing Jie, Kang, Seungha, Hamilton, Amy L., O'Brien, Amy Wilson, Ching, Jessica Y., Sun, Yang, Miao, Yinglei, Sung, Joseph J.Y., Yu, Jun, Morrison, Mark, Kamm, Michael A. and Ng, Siew C. (2024). The Role Of Proteus Mirabilis And Its Derived Metabolite Cadaverine In Altering Bacterial Composition And Metabolite Profile In Crohn's Disease. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)01743-8
2024
Conference Publication
Metagenomic Analysis Of Intra-household Transmission Patterns Of The Gut Microbiome In Crohn's Disease Across Populations
Zhang, Jingwan, Zheng, Jiaying, Sun, Qianru, Teh, Jing Jie, Kang, Seungha, Hamilton, Amy L., Brien, Amy Wilson O’, Ching, Jessica Y., Sun, Yang, Miao, Yinglei, Sung, Joseph J.Y., Yu, Jun, Morrison, Mark, Kamm, Michael A. and Ng, Siew C. (2024). Metagenomic Analysis Of Intra-household Transmission Patterns Of The Gut Microbiome In Crohn's Disease Across Populations. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)00569-9
2024
Conference Publication
Quantifying Artificial Sweeteners And Emulsifiers In Crohn's Disease And Their Relationship With Disease With Disease Activity. The ENIGMA Study
Hu, Jielun, Zhang, Jingwan, Ruan, Yanjiao, Trakman, Gina L., Hamilton, Amy L., Lin, Winnie Y., Sun, Yang, Ching, Jessica Y., Teh, Jing Jie, Kang, Seungha, O’Brien, Amy Wilson, Stanley, Annalise, Sung, Joseph J.Y., Yu, Jun, Miao, Yinglei, Morrison, Mark, Kamm, Michael A. and Ng, Siew C. (2024). Quantifying Artificial Sweeteners And Emulsifiers In Crohn's Disease And Their Relationship With Disease With Disease Activity. The ENIGMA Study. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)03360-2
2024
Conference Publication
The Duodenal Mucosa-associated Microbiota Of Patients With A Disorder Of Gut-brain Interaction Can Be Differentiated By Rome IV Criteria
Schooth, Lauren F., Kang, Seungha, Fairlie, Thomas, Lim, Yenkai, Teh, Jing Jie, Hoedt, Emily C., Keely, Simon, Shah, Ayesha, Holtmann, Gerald J. and Morrison, Mark (2024). The Duodenal Mucosa-associated Microbiota Of Patients With A Disorder Of Gut-brain Interaction Can Be Differentiated By Rome IV Criteria. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)02266-2
2024
Conference Publication
The Key Anti-inflammatory Bacterium Faecalibacterium Prausnitzii Is More Complex And Diverse Than Previously Recognised: Anatomic, Geographic, And Genomic Differences In The East And West And In Health And Crohn's Disease. The ENIGMA Study
Teh, Jing Jie, Kang, Seungha, Leonard, Alarna, Zhang, Jingwan, Zheng, Jiaying, Hu, Jielun, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Stanley, Annalise, Ching, Jessica Y., Lin, Winnie Y., Sung, Joseph J.Y., Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2024). The Key Anti-inflammatory Bacterium Faecalibacterium Prausnitzii Is More Complex And Diverse Than Previously Recognised: Anatomic, Geographic, And Genomic Differences In The East And West And In Health And Crohn's Disease. The ENIGMA Study. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)01742-6
2024
Conference Publication
Crohn's Disease Mucosal Microbiota Virulence Factor Gene Analysis Identifies Antibiotic Resistant Enterococcus Faecalis Linked To Immune Activation. The ENIGMA Study
Teh, Jing Jie, Kang, Seungha, Zhang, Jingwan, Hu, Jielun, Zheng, Jiaying, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Stanley, Annalise, Ching, Jessica Y., Lin, Winnie Y., Sung, Joseph JY, Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2024). Crohn's Disease Mucosal Microbiota Virulence Factor Gene Analysis Identifies Antibiotic Resistant Enterococcus Faecalis Linked To Immune Activation. The ENIGMA Study. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)01741-4
2024
Journal Article
Identification of the mechanism for dehalorespiration of monofluoroacetate in the phylum Synergistota
Leong, Lex E. X., Denman, Stuart E., Kang, Seungha, Mondot, Stanislas, Hugenholtz, Philip and McSweeney, Chris S. (2024). Identification of the mechanism for dehalorespiration of monofluoroacetate in the phylum Synergistota. Animal Bioscience, 37 (2), 396-403. doi: 10.5713/ab.23.0351
2023
Journal Article
Effects of different feeding systems on ruminal fermentation, digestibility, methane emissions, and microbiota of Hanwoo steers
Lee, Seul, Kim, Jungeun, Baek, Youlchang, Seong, Pilnam, Song, Jaeyong, Kim, Minseok and Kang, Seungha (2023). Effects of different feeding systems on ruminal fermentation, digestibility, methane emissions, and microbiota of Hanwoo steers. Journal of Animal Science and Technology, 65 (6), 1270-1289. doi: 10.5187/jast.2023.e82
2023
Conference Publication
The Secretomes Of Colonic Mucosa-associated Microbiota In Crohn's Disease And Health Identify Key Bacteria Driving Pro- And Anti-inflammatory Responses. The Enigma Study
Teh, Jing Jie, Kang, Seungha, Zhang, Jingwan, Hu, Jielun, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Lin, Winnie Y., Ching, Jessica Y., Sung, Joseph JY, Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2023). The Secretomes Of Colonic Mucosa-associated Microbiota In Crohn's Disease And Health Identify Key Bacteria Driving Pro- And Anti-inflammatory Responses. The Enigma Study. Digestive Disease Week (DDW) 2023, Chicago, IL United States, 6-9 May 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(23)03117-7
2023
Conference Publication
CHARACTERIZATION OF THE COLONIC MUCOSA-ASSOCIATED METAGENOME REVEALS NOVEL MICROBES AND GEOGRAPHICALLY DISTINCT COMMUNITIES IN HEALTH AND CROHN'S DISEASE. THE ENIGMA STUDY
Kang, Seungha, Teh, Jing Jie, Zhang, Jingwan, Hu, Jielun, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Lin, Winnie Y., Ching, Jessica Y., Sung, Joseph J. Y., Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2023). CHARACTERIZATION OF THE COLONIC MUCOSA-ASSOCIATED METAGENOME REVEALS NOVEL MICROBES AND GEOGRAPHICALLY DISTINCT COMMUNITIES IN HEALTH AND CROHN'S DISEASE. THE ENIGMA STUDY. Digestive Disease Week (DDW), Chicago Il, May 06-09, 2023. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2023
Conference Publication
Characterization Of The Colonic Mucosa-associated Metagenome Reveals Novel Microbes And Geographically Distinct Communities In Health And Crohn's Disease. The Enigma Study
Kang, Seungha, Teh, Jing Jie, Zhang, Jingwan, Hu, Jielun, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Lin, Winnie Y., Ching, Jessica Y., Sung, Joseph JY, Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2023). Characterization Of The Colonic Mucosa-associated Metagenome Reveals Novel Microbes And Geographically Distinct Communities In Health And Crohn's Disease. The Enigma Study. Digestive Disease Week (DDW) 2023, Chicago, IL United States, 6-9 May 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(23)03125-6
2023
Conference Publication
IMPACT OF EPIDEMIOLOGIC EVOLUTION, DIET AND EARLY LIFE PROCESSED FOOD INTAKE ON MICROBIOME VARIANCE IN CROHN'S DISEASE. THE INTERNATIONAL ENIGMA STUDY
Zhang, Jingwan, Sun, Qianru, Teh, Jing Jie, Kang, Seungha, Hu, Jielun, Lin, Winnie Y., Trakman, Gina L., Sun, Yang, Hamilton, Amy L., Brien, Amy Wilson O', Ching, Jessica Y., Miao, Yinglei, Sung, Joseph J. Y., Yu, Jun, Morrison, Mark, Kamm, Michael A. and Ng, Siew C. (2023). IMPACT OF EPIDEMIOLOGIC EVOLUTION, DIET AND EARLY LIFE PROCESSED FOOD INTAKE ON MICROBIOME VARIANCE IN CROHN'S DISEASE. THE INTERNATIONAL ENIGMA STUDY. Digestive Disease Week (DDW), Chicago Il, May 06-09, 2023. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2023
Conference Publication
Variations Of The Mucosa Associated Microbiome In Patients With Primary Sclerosing Cholangitis, Ulcerative Colitis And Asymptomatic Controls Along The Gastrointestinal Tract
Shah, Ayesha, Kang, Seungha, Fairlie, Thomas, Morrison, Mark and Holtmann, Gerald J. (2023). Variations Of The Mucosa Associated Microbiome In Patients With Primary Sclerosing Cholangitis, Ulcerative Colitis And Asymptomatic Controls Along The Gastrointestinal Tract. Digestive Disease Week (DDW) 2023, Chicago, IL United States, 6-9 May 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(23)01543-3
2023
Conference Publication
Density of the mucosal bacterial colonization along the gastrointestinal tract in health and disease
Shah, Ayesha, Sternes, Peter R., Kang, Seungha, Pintos, Camila Ayala, Fairlie, Thomas, Tyson, Gene W., Morrison, Mark and Holtmann, Gerald J. (2023). Density of the mucosal bacterial colonization along the gastrointestinal tract in health and disease. Digestive Disease Week (DDW), Chicago, IL, United States, 6-9 May 2023. Philadelphia, PA, United States: Elsevier. doi: 10.1016/S0016-5085(23)03108-6
2023
Conference Publication
Characterization Of The Key Anti-inflammatory Bacterium Faecalibacterium Prausnitzii Internationally In Health And Crohn's Disease. The Enigma Study
Teh, Jing Jie, Kang, Seungha, Leonard, Alarna, Zhang, Jingwan, Hu, Jielun, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Lin, Winnie Y., Ching, Jessica Y., Sung, Joseph JY, Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2023). Characterization Of The Key Anti-inflammatory Bacterium Faecalibacterium Prausnitzii Internationally In Health And Crohn's Disease. The Enigma Study. Digestive Disease Week (DDW) 2023, Chicago, IL United States, 6-9 May 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(23)03121-9
2023
Conference Publication
CHARACTERIZATION OF THE KEY ANTI-INFLAMMATORY BACTERIUM FAECALIBACTERIUM PRAUSNITZII INTERNATIONALLY IN HEALTH AND CROHN'S DISEASE. THE ENIGMA STUDY
Teh, Jing Jie, Kang, Seungha, Leonard, Alarna, Zhang, Jingwan, Hu, Jielun, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Lin, Winnie Y., Ching, Jessica Y., Sung, Joseph Jy, Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2023). CHARACTERIZATION OF THE KEY ANTI-INFLAMMATORY BACTERIUM FAECALIBACTERIUM PRAUSNITZII INTERNATIONALLY IN HEALTH AND CROHN'S DISEASE. THE ENIGMA STUDY. Digestive Disease Week (DDW), Chicago Il, May 06-09, 2023. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2023
Journal Article
Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia
Shanahan, Erin R., Kang, Seungha, Staudacher, Heidi, Shah, Ayesha, Do, Anh, Burns, Grace, Chachay, Veronique S., Koloski, Natasha A., Keely, Simon, Walker, Marjorie M., Talley, Nicholas J., Morrison, Mark and Holtmann, Gerald J. (2023). Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia. Gut, 72 (5) 326158, 929-938. doi: 10.1136/gutjnl-2021-326158
Funding
Current funding
Supervision
Availability
- Dr Seungha Kang is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Media
Enquiries
For media enquiries about Dr Seungha Kang's areas of expertise, story ideas and help finding experts, contact our Media team: