Overview
Background
My current appointment is Director of Kidney Services at Redland Hospitals in Metro South, Brisbane, where I practice as a senior consultant nephrologist.
My research interests are varied and include post-transplant anaemia and iron metabolism, and novel measures of iron status such as hepcidin; improving dialysis outcomes though the implementation of evidence-based guidelines; kidney disease due to thrombotic microangiopathy (particularly aHUS) and the role of inhibitors of the complement system in kidney disease; and the use of honey to prevent infections in dialysis patients.
I am committed to teaching medical students and young nephrologists, and am actively involved in medical education at all levels.
Availability
- Professor David Mudge is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine, of Surgery and of Obstetrics, The University of Queensland
- Doctoral (Research) of Medicine, The University of Queensland
Research impacts
The impact of my research in peritoneal dialysis has been a significant improvement in PD-related infection rates in Australia, which until a few years ago were worse than many other countries in the world. Through a variety of initiatives including a project aiming to improve the use of evidence-based guidelines in clinical practice, we have seen a significant improvement in PD-related infections (particularly peritonitis but also exit-site infections), one of the most significant contributors to peritoneal dialysis technique failure.
In kidney transplantation my research has helped to clarify the role of immune suppressing medications on iron availability and anaemia and has looked at novel ways of measuring iron status in patients with kidney disease as well as better ways of enhancing iron stores in these patients.
Works
Search Professor David Mudge’s works on UQ eSpace
2006
Conference Publication
Effectiveness of a cardiovascular risk factor modification program in insulin-resistant renal transplant recipients
Armstrong, K., Johnson, D., De Silva, N., Pidcock, R., Orazio, L., Prins, J., Campbell, S., Hawley, C., Mudge, D., Marwick, T. and Isbel, N. (2006). Effectiveness of a cardiovascular risk factor modification program in insulin-resistant renal transplant recipients. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand, The Australian Academy of Science Canberra, ACT, Australia, 29–31 March 2006. Basingstoke, U. K.: Transplantation Society of Australia and New Zealand. doi: 10.1111/j.1440-1711.2006.01450.x
2006
Conference Publication
Outcomes of kidney transplant recipients on Warfarin at time of transplant
Wong, J. S., Campbell, S. B., Hawley, C. M., Johnson, D. W., Mudge, D. W. and Isbel, N. M. (2006). Outcomes of kidney transplant recipients on Warfarin at time of transplant. 42nd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, Australia, 14–18 August 2006. Hoboken, NJ United States: Wiley-Blackwell.
2006
Conference Publication
Estimated donor GFR is the most important donor characteristic predicting graft function in recipients of live donor kidneys
Mudge, D. W., Hawley, C. M., Johnson, D., Isbel, N. M., Campbell, S. B., Griffin, A., Preston, J. and Nicol, D. (2006). Estimated donor GFR is the most important donor characteristic predicting graft function in recipients of live donor kidneys. 42nd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, Australia, 14–18 August 2006. Hoboken, NJ United States: Wiley-Blackwell.
2006
Journal Article
Estimated donor glomerular filtration rate is the most important donor characteristic predicting graft function in recipients of kidneys from live donors
Hawley, Carmel M., Kearsley, Jamie, Campbell, Scott B., Mudge, David, Isbel, Nicole M., Johnson, David W., May, Kylie, Preston, John, Griffin, Anthony, Wall, Daryl, Burke, John, McTaggart, Steven J., Frohloff, Gayle and Nicol, David (2006). Estimated donor glomerular filtration rate is the most important donor characteristic predicting graft function in recipients of kidneys from live donors. Transplant International, 20 (1), 64-72. doi: 10.1111/j.1432-2277.2006.00400.x
2006
Journal Article
Effect of previously failed kidney transplantation on peritoneal dialysis outcomes in the Australian and New Zealand patient populations
Badve, Sunil V., Hawley, Carmel M., McDonald, Stephen P., Mudge, David W., Rosman, Johan B., Brown, Fiona G., Johnson, David W. and ANZDATA Registry PD Working Comm (2006). Effect of previously failed kidney transplantation on peritoneal dialysis outcomes in the Australian and New Zealand patient populations. Nephrology Dialysis Transplantation, 21 (3), 776-783. doi: 10.1093/ndt/gfi248
2006
Conference Publication
Bone histology in alternate nightly home haemodialysis
van Eps, Carolyn, Jeffries, Janine, Diamond, Terrence, Anderson, John, Johnson, David, Campbell, Scott, Isbel, Nicole, Mudge, David and Hawley, Carmel (2006). Bone histology in alternate nightly home haemodialysis. 43rd ERA-EDTA Congress, Glasgow, Scotland, 15-18 July 2006 . Oxford, United Kingdom: Oxford University Press.
2006
Journal Article
Deceased donor renal transplantation - does side matter?
Johnson, David W., Mudge, David W., Kaisar, Mohammed O., Campbell, Scott B., Hawley, Carmel M., Isbel, Nicole M., Wall, Daryl, Griffin, Anthony, Preston, John and Nicol, David L. (2006). Deceased donor renal transplantation - does side matter?. Nephrology Dialysis Transplantation, 21 (9), 2583-2588. doi: 10.1093/ndt/gfl268
2006
Conference Publication
A randomized, controlled trial of coiled versus straight swan neck tenckhoff catheters in peritoneal dialysis patients
Wong, J. S., Wiggins, K. J., Campbell, S. B., Isbel, N. M., Mudge, D. W., Hawley, C. M. and Johnson, D. W. (2006). A randomized, controlled trial of coiled versus straight swan neck tenckhoff catheters in peritoneal dialysis patients. 42nd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, Australia, 14–18 August 2006. Hoboken, NJ United States: Wiley-Blackwell.
2006
Conference Publication
Effectiveness of a cardiovascular risk factor modification program in insulin-resistant renal transplant recipients
Armstrong, K., Johnson, D., De Silva, N., Pidcock, R., Orazio, L., Prins, J., Campbell, S., Hawley, C., Mudge, D., Marwick, T. and Isbel, N. (2006). Effectiveness of a cardiovascular risk factor modification program in insulin-resistant renal transplant recipients. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand, Canberra, Australia, 29–31 March 2006. Oxford, United Kingdom: John Wiley & Sons.
2005
Journal Article
Hepatic vein stenting for recurrent ascites in polycystic liver and kidney disease
Mudge, DW, Taylor, J and Bannister, KM (2005). Hepatic vein stenting for recurrent ascites in polycystic liver and kidney disease. Nephrology Dialysis Transplantation, 20 (11), 2566-2568. doi: 10.1093/ndt/gfi051
2005
Journal Article
Pharmacokinetics and normal scintigraphic appearance of 99mTc aprotinin
Sojan, SM, Smyth, DR, Tsopelas, C, Mudge, D, Collins, PJ and Chatterton, BE (2005). Pharmacokinetics and normal scintigraphic appearance of 99mTc aprotinin. Nuclear Medicine Communications, 26 (6), 535-539. doi: 10.1097/00006231-200506000-00009
2005
Journal Article
Obliterative bronchiotitis or opportunistic infection? A diagnostic challenge in a renal transplant patient (Letter to the Editor)
Mudge, David W., Johnson, David W., Isbel, Nicole M., Campbell, Scott B., Nicol, David L. and Hawley, Carmel M. (2005). Obliterative bronchiotitis or opportunistic infection? A diagnostic challenge in a renal transplant patient (Letter to the Editor). Nephrology Dialysis Transplantation, 20 (1), 246-247. doi: 10.1093/ndt/gfh580
2005
Journal Article
Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus Mupirocin for the prevention of catheter-associated infections in hemodialysis patients
Johnson, David Wayne, van Eps, Carolyn, Mudge, David William, Wiggins, Kathryn Joan, Armstrong, Kirsty, Hawley, Carmel Mary, Campbell, Scott Bryan, Isbel, Nicole Maree, Nimmo, Graeme Robert and Gibbs, Harry (2005). Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus Mupirocin for the prevention of catheter-associated infections in hemodialysis patients. Journal of The American Society of Nephrology, 16 (5), 1456-1462. doi: 10.1681/ASN.2004110997
2005
Journal Article
Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant
Atcheson, Bronwyn A., Taylor, Paul J., Mudge, David W., Johnson, David W., Hawley, Carmel M., Campbell, Scott B., Isbel, Nicole M., Pillans, Peter I. and Tett, Susan E. (2005). Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant. British Journal of Clinical Pharmacology, 59 (3), 271-280. doi: 10.1111/j.1365-2125.2004.02235.x
2005
Journal Article
Randomized trial of FX high flux vs standard high flux dialysis for homocysteine clearance
Mudge, David W., Rogers, Robyn, Hollett, Peter, Law, Belinda, Reiger, Kylie, Petrie, James J. B., Price, Lee, Johnson, David W., Campbell, Scott B., Isbel, Nicole M., Sullivan, Matthew and Hawley, Carmel M. (2005). Randomized trial of FX high flux vs standard high flux dialysis for homocysteine clearance. Nephrology Dialysis Transplantation, 20 (10), 2178-2185. doi: 10.1093/ndt/gfh987
2004
Journal Article
Response: Iron Therapy in Renal Transplant Recipients
Johnson, David W., Mudge, David W., Atcheson, Bronwyn, Taylor, Paul J., Sturtevant, Joanna M., Hawley, Carmel M., Campbell, Scott B., Isbel, Nicole M., Nicol, David L. and Pillans, Peter (2004). Response: Iron Therapy in Renal Transplant Recipients. Transplantation, 78 (8), 1240-1240. doi: 10.1097/01.TP.0000137102.92992.5F
2004
Journal Article
Coca-Cola and kangaroos (Case report)
Mudge, David W. and Johnson, David W. (2004). Coca-Cola and kangaroos (Case report). Lancet, 364 (9440), 1190-1190. doi: 10.1016/S0140-6736(04)17111-0
2004
Journal Article
Severe Toxicity Associated with a Markedly Elevated Mycophenolic Acid Free Fraction in a Renal Transplant Recipient
Mudge, David, Atcheson, Bronwyn, Taylor, Paul, Pillans, Peter and Johnson, David (2004). Severe Toxicity Associated with a Markedly Elevated Mycophenolic Acid Free Fraction in a Renal Transplant Recipient. Therapeutic Drug Monitoring, 26 (4), 453-455. doi: 10.1097/00007691-200408000-00017
2004
Journal Article
Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia
Atcheson, Bronwyn A., Taylor, Paul J., Kirkpatrick, Carl M. J., Duffull, Stephen B., Mudge, David W., Pillans, Peter I., Johnson, David W. and Tett, Susan E. (2004). Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia. Therapeutic Drug Monitoring, 26 (3), 284-286. doi: 10.1097/00007691-200406000-00011
2004
Journal Article
The effect of oral iron administration on mycophenolate mofetil absorption in renal transplant recipients: a randomized, controlled trial
Mudge, David W., Taylor, Paul J., Atcheson, Bronwyn A., Sturtevant, Joanna M., Hawley, Carmel M., Campbell, Scott B., Isbel, Nicole M., Nicol, David L., Pillans, Peter I. and Johnson, David W. (2004). The effect of oral iron administration on mycophenolate mofetil absorption in renal transplant recipients: a randomized, controlled trial. Transplantation, 77 (2), 206-209. doi: 10.1097/01.TP.0000100446.44001.00
Funding
Past funding
Supervision
Availability
- Professor David Mudge is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Master Philosophy
Very early acute rejection in an Australian and New Zealand kidney transplant population
Principal Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley, Associate Professor Yeoung Jee Cho, Associate Professor Ross Francis
-
2015
Doctor Philosophy
Inflammation in Peritoneal Dialysis: Investigating the Roles of Biocompatible Solutions and Biological Markers
Associate Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley
Media
Enquiries
Contact Professor David Mudge directly for media enquiries about:
- Anaemia
- Chronic kidney disease
- Iron regulation
- Kidney disease
- Kidney transplantation
- Organ transplant - kidney
- Transplant - kidney
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