
Overview
Background
My current appointment is Director of Kidney Services at Redland Hospitals in Metro South, Brisbane, where I practice as a senior consultant nephrologist.
My research interests are varied and include post-transplant anaemia and iron metabolism, and novel measures of iron status such as hepcidin; improving dialysis outcomes though the implementation of evidence-based guidelines; kidney disease due to thrombotic microangiopathy (particularly aHUS) and the role of inhibitors of the complement system in kidney disease; and the use of honey to prevent infections in dialysis patients.
I am committed to teaching medical students and young nephrologists, and am actively involved in medical education at all levels.
Availability
- Professor David Mudge is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine, of Surgery and of Obstetrics, The University of Queensland
- Doctoral (Research) of Medicine, The University of Queensland
Research impacts
The impact of my research in peritoneal dialysis has been a significant improvement in PD-related infection rates in Australia, which until a few years ago were worse than many other countries in the world. Through a variety of initiatives including a project aiming to improve the use of evidence-based guidelines in clinical practice, we have seen a significant improvement in PD-related infections (particularly peritonitis but also exit-site infections), one of the most significant contributors to peritoneal dialysis technique failure.
In kidney transplantation my research has helped to clarify the role of immune suppressing medications on iron availability and anaemia and has looked at novel ways of measuring iron status in patients with kidney disease as well as better ways of enhancing iron stores in these patients.
Works
Search Professor David Mudge’s works on UQ eSpace
2009
Journal Article
Adiponectin is associated with cardiovascular disease in male renal transplant recipients: baseline results from the LANDMARK 2 study
Kaisar, Mohd, Armstrong, Kirsten, Hawley, Carmel, Campbell, Scott, Mudge, David, Johnson, David W., Prins, John B. and Isbel, Nicole M. (2009). Adiponectin is associated with cardiovascular disease in male renal transplant recipients: baseline results from the LANDMARK 2 study. BMC Nephrology, 10 (29) 29, xxx-xxx. doi: 10.1186/1471-2369-10-29
2009
Journal Article
Rationale and design of the HEALTHY-CATH trial: A randomised controlled trial of Heparin versus EthAnol Lock THerapY for the prevention of catheter associated infecTion in haemodialysis patients
Broom, Jennifer, O'Shea, Stacey, Govindarajula, Sridevi, Playford, Geoffrey, Hawley, Carmel M., Isbel, Nicole M., Campbell, Scott, Mudge, David, Carpenter, Sally, Johnson, Barbara, Underwood, Neil and Johnson, David W. (2009). Rationale and design of the HEALTHY-CATH trial: A randomised controlled trial of Heparin versus EthAnol Lock THerapY for the prevention of catheter associated infecTion in haemodialysis patients. BMC Nephrology, 10 (23) 23, xxx-xxx. doi: 10.1186/1471-2369-10-23
2009
Journal Article
Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal dialysis patients (HEMATOCRIT trial)
Barraclough, Katherine A., Noble, Euan, Leary, Diane, Brown, Fiona, Hawley, Carmel M., Campbell, Scott B., Isbel, Nicole M., Mudge, David, van Eps, Carolyn L., Sturtevant, Joanna M. and Johnson, David W. (2009). Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal dialysis patients (HEMATOCRIT trial). BMC Nephrology, 10 (1) 20, 20-1-20-7. doi: 10.1186/1471-2369-10-20
2009
Journal Article
Intradermal versus intramuscular hepatitis B vaccination in hemodialysis patients: A prospective open-label randomized controlled trial in nonresponders to primary vaccination
Barraclough, Katherine A., Wiggins, Kathryn J, Hawley, Carmel M., van Eps, Carolyn L., Mudge, David W., Johnson, David W., Whitby, Michael, Carpenter, Sally and Playford, E. Geoffrey (2009). Intradermal versus intramuscular hepatitis B vaccination in hemodialysis patients: A prospective open-label randomized controlled trial in nonresponders to primary vaccination. American Journal of Kidney Diseases, 54 (1), 95-103. doi: 10.1053/j.ajkd.2009.03.010
2009
Journal Article
Intravenous versus oral iron supplementation for correction of post-transplant anaemia in renal transplant patients
Mudge, David, Tan, Ken-Soon, Miles, Rhianna, Johnson, David W., Campbell, Scott, Hawley, Carmel M., Isbel, Nicole M., Van Eps, Carolyn and Nicol, David L. (2009). Intravenous versus oral iron supplementation for correction of post-transplant anaemia in renal transplant patients. BMC Nephrology, 10 (1) 14, 14.1-14.3. doi: 10.1186/1471-2369-10-14
2009
Journal Article
Life-threatening adenovirus infection in a kidney transplant recipient
Barraclough, Katherine, Oliver, Kimberley, Playford, Elliot Geoffrey, Preston, John, Campbell, Scott, Johnson, David W., Hawley, Carmel, Mudge, David, van Eps, Carolyn and Isbel, Nicole (2009). Life-threatening adenovirus infection in a kidney transplant recipient. NDT Plus, 2 (3), 250-253. doi: 10.1093/ndtplus/sfp003
2009
Journal Article
Effect of FX dialysers on systemic inflammation and quality of life in chronic haemodialysis patients
Boudville, Neil, Horner, Marilyn, McEwan, Elizabeth, Lim, Wai H., Mudge, David W. and Markus, Hadley E. (2009). Effect of FX dialysers on systemic inflammation and quality of life in chronic haemodialysis patients. Blood Purification, 27 (2), 187-193. doi: 10.1159/000190786
2009
Conference Publication
Aminoglycosides in haemodialysis patients: Should we be dosing pre-dialysis rather then post-dialysis?
O'Shea, S., Duffull, S., Johnson, D. W. and Mudge, D. (2009). Aminoglycosides in haemodialysis patients: Should we be dosing pre-dialysis rather then post-dialysis?. 45th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Hobart, TAS, Australia, 7–9 September 2009. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2009.01176.x
2009
Conference Publication
NO IMPROVEMENT IN CARDIAC STRUCTURE AND FUNCTION IN ALTERNATE NIGHTLY HAEMODIALYSIS
Van Eps, CL, Jeffries, L, Haluska, B, Hawley, CM, Jeffries, J, Johnson, DW, Campbell, SB, Isbel, NM, Mudge, DW and Marwick, TH (2009). NO IMPROVEMENT IN CARDIAC STRUCTURE AND FUNCTION IN ALTERNATE NIGHTLY HAEMODIALYSIS. 45th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Hobart, Australia, 7–9 September 2009. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.
2009
Conference Publication
Oxidative stress markers in alternate nightly noctural haemodialysis
Van Eps, CL, Coombes, JS, Matsumoto, A, Jeffries, JK, Johnson, DW, Campbell, SB, Isbel, NM, Mudge, DW and Hawley, CM (2009). Oxidative stress markers in alternate nightly noctural haemodialysis. 45th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrolog, Hobart, Tasmania, Australia, 7–9 September 2009. Carlton, Vic., Australia: Blackwell Science. doi: 10.1111/j.1440-1797.2009.001176.x
2009
Conference Publication
Renal transplantation for antiphospholipid syndrome without reversal of warfarin
Baer, R., Mudge, D. W., Campbell, S. B. and Ray, M. (2009). Renal transplantation for antiphospholipid syndrome without reversal of warfarin. 45th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Hobart, Tasmania, Australia, 7–9 September 2009. Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2009.01176.x
2009
Conference Publication
Vascular structure and function in alternate nightly nocturnal haemodialysis
Van Eps, C. L., Jeffries, L., Haluska, B., Hawley, C. M., Jeffries, J., Johnson, D. W., Campbell, S. B., Isbel, N. M., Mudge, D. W. and Marwick, T. H. (2009). Vascular structure and function in alternate nightly nocturnal haemodialysis. 45th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology , Hobart, Tasmania, Australia, 7–9 September 2009. Hoboken, NJ United States: Wiley-Blackwell.
2009
Conference Publication
Body mass index is independently associated with inflammatory burden in patients with chronic kidney disease
Petchey, WG, Campbell, S, Van Eps, C, Mudge, D, Johnson, D, Hawley, C and Isbel, N (2009). Body mass index is independently associated with inflammatory burden in patients with chronic kidney disease. 45th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Hobart, Australia, 7 - 9 September, 2009. Carlton, Australia: Wiley InterScience. doi: 10.1111/j.1440-1797.2009.01176.x
2009
Conference Publication
Anaemia prevalence among new referrals to nephrology outpatients in South East Queensland
Noble, E. P., Gray, N. A., Johnson, D. W., Hollett, P. R., Hawley, C. M., Campbell, S. B., Mudge, D. W. and Isbel, N. M. (2009). Anaemia prevalence among new referrals to nephrology outpatients in South East Queensland. 45th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Tasmania, Australia, 7–9 September 2009. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1797.2009.01176.x
2008
Conference Publication
Previous treatment modality of patients entering a contemporary home haemodialysis program: a minority transfer from peritoneal dialysis
Miles, R., Van Eps, C., Jeffries, J., Johnson, D., Campbell, S., Isbel, N., Mudge, D., Burke, J. and Hawley, C. (2008). Previous treatment modality of patients entering a contemporary home haemodialysis program: a minority transfer from peritoneal dialysis. 44th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Sydney, NSW Australia, 6–10 September 2008. Richmond, VIC Australia: John Wiley and Sons.
2008
Conference Publication
Chronic kidney disease following orthotopic liver transplantion
Frazier, J., Lipka, G., Johnson, D., Hawley, C., Campbell, S., Mudge, D., Van Eps, C., Isbel, N. and Macdonald, G. (2008). Chronic kidney disease following orthotopic liver transplantion. Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Newcastle, Australia, 6–10 September 2008. Richmond, VIC, Australia: Wiley-Blackwell.
2008
Conference Publication
PAINFUL LEFT BREAST IN A PATIENT WITH ESKD: A DIAGNOSTIC PROBLEM
Govindarajulu, S., Frazier, J., Van Eps, C., Isbel, N., Campbell, S., Johnson, D., Mudge, D. and Hawley, C. (2008). PAINFUL LEFT BREAST IN A PATIENT WITH ESKD: A DIAGNOSTIC PROBLEM. HOBOKEN: WILEY-BLACKWELL.
2008
Journal Article
Induction and maintenance therapy in ANCA-associated systemic vasculitis
Menahem, Solomon, Hiremagalur, Balaji, Mudge, David, Toussaint, Nigel and Walters, Giles (2008). Induction and maintenance therapy in ANCA-associated systemic vasculitis. Nephrology, 13 (Supp. 2), S24-S36. doi: 10.1111/j.1440-1797.2008.00995.x
2008
Journal Article
Automated and continuous ambulatory peritoneal dialysis have similar outcomes
Badve, S., Hawley, C. M., McDonald, S., Mudge, D., Rosman, J., Brown, F. and Johnson, D. W. (2008). Automated and continuous ambulatory peritoneal dialysis have similar outcomes. Kidney International, 73 (4), 480-488. doi: 10.1038/sj.ki.5002705
2008
Journal Article
The impact of automated eGFR reporting and education on nephrology service referrals
Noble, E, Johnson, DW, Gray, N, Hollett, P, Hawley, CM, Campbell, SB, Mudge, DW and Isbel, NM (2008). The impact of automated eGFR reporting and education on nephrology service referrals. Nephrology, Dialysis, Transplantation, 23 (12), 3845-3850. doi: 10.1093/ndt/gfn385
Funding
Past funding
Supervision
Availability
- Professor David Mudge is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Master Philosophy
Very early acute rejection in an Australian and New Zealand kidney transplant population
Principal Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley, Associate Professor Yeoung Jee Cho, Associate Professor Ross Francis
-
2015
Doctor Philosophy
Inflammation in Peritoneal Dialysis: Investigating the Roles of Biocompatible Solutions and Biological Markers
Associate Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley
Media
Enquiries
Contact Professor David Mudge directly for media enquiries about:
- Anaemia
- Chronic kidney disease
- Iron regulation
- Kidney disease
- Kidney transplantation
- Organ transplant - kidney
- Transplant - kidney
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