Overview
Background
My current appointment is Director of Kidney Services at Redland Hospitals in Metro South, Brisbane, where I practice as a senior consultant nephrologist.
My research interests are varied and include post-transplant anaemia and iron metabolism, and novel measures of iron status such as hepcidin; improving dialysis outcomes though the implementation of evidence-based guidelines; kidney disease due to thrombotic microangiopathy (particularly aHUS) and the role of inhibitors of the complement system in kidney disease; and the use of honey to prevent infections in dialysis patients.
I am committed to teaching medical students and young nephrologists, and am actively involved in medical education at all levels.
Availability
- Professor David Mudge is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine, of Surgery and of Obstetrics, The University of Queensland
- Doctoral (Research) of Medicine, The University of Queensland
Research impacts
The impact of my research in peritoneal dialysis has been a significant improvement in PD-related infection rates in Australia, which until a few years ago were worse than many other countries in the world. Through a variety of initiatives including a project aiming to improve the use of evidence-based guidelines in clinical practice, we have seen a significant improvement in PD-related infections (particularly peritonitis but also exit-site infections), one of the most significant contributors to peritoneal dialysis technique failure.
In kidney transplantation my research has helped to clarify the role of immune suppressing medications on iron availability and anaemia and has looked at novel ways of measuring iron status in patients with kidney disease as well as better ways of enhancing iron stores in these patients.
Works
Search Professor David Mudge’s works on UQ eSpace
2012
Journal Article
Changes in serum prolactin, sex hormones and thyroid function with alternate nightly nocturnal home haemodialysis
Van Eps, Carolyn, Hawley, Carmel, Jeffries, Janine, Johnson, David W., Campbell, Scott, Isbel, Nicole, Mudge, David W. and Prins, Johannes (2012). Changes in serum prolactin, sex hormones and thyroid function with alternate nightly nocturnal home haemodialysis. Nephrology, 17 (1), 42-47. doi: 10.1111/j.1440-1797.2011.01520.x
2012
Journal Article
Achieving salt restriction in chronic kidney disease
McMahon, Emma J., Campbell, Katrina L., Mudge, David W. and Bauer, Judith D. (2012). Achieving salt restriction in chronic kidney disease. International Journal of Nephrology, 2012 720429, 720429.1-720429.10. doi: 10.1155/2012/720429
2012
Conference Publication
Two cases of atypical haemolytic uremic syndrome treated with Eculizumab
Bose, B., Mallett, A., Badve, S. V., Johnson, D. W., Hawley, C., Mudge, D., Van Eps, C., Campbell, S. and Isbel, N. (2012). Two cases of atypical haemolytic uremic syndrome treated with Eculizumab. 48th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Auckland, New Zealand, 27‐29 August 2012. Hoboken, NJ United States: Wiley-Blackwell.
2012
Conference Publication
NXSTAGE Queensland health pilot program the early Australian NXSTAGE experience: is NXSTAGE really the next stage in home haemodialysis?
Lee, A., Killen, J-P., Hawley, C., Jeffries, J., Equinox, K., Johnson, D., Campbell, S., Isbel, N., Mudge, D., Badve, S. and Van Eps, C. (2012). NXSTAGE Queensland health pilot program the early Australian NXSTAGE experience: is NXSTAGE really the next stage in home haemodialysis?. 48th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Auckland, New Zealand, 27‐29 August 2012. Hoboken, NJ United States: Wiley-Blackwell Publishing.
2011
Journal Article
Cardiac and vascular structure and function parameters do not improve with alternate nightly home hemodialysis: An interventional cohort study
van Eps, Carolyn L., Jeffriess, Leanne, Haluska, Brian, Hawley, Carmel M., Coombes, Jeffrey, Matsumoto, Aya, Janine K Jeffries, Johnson, David W., Campbell, Scott B., Isbel, Nicole M. and Mudge, David W. (2011). Cardiac and vascular structure and function parameters do not improve with alternate nightly home hemodialysis: An interventional cohort study. BMC Nephrology, 12 (51) 51, 1-15. doi: 10.1186/1471-2369-12-51
2011
Conference Publication
NURSE PRACTITIONER EXPANDED PRACTICE AND PATIENT SAFETY WITH REMOVAL OF CENTRAL VENOUS DIALYSIS CATHETERS
Mills, K. A. and Mudge, D. W. (2011). NURSE PRACTITIONER EXPANDED PRACTICE AND PATIENT SAFETY WITH REMOVAL OF CENTRAL VENOUS DIALYSIS CATHETERS. MALDEN: WILEY-BLACKWELL.
2011
Journal Article
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): A randomised placebo-controlled trial
Baigent, Colin, Landray, Martin J., Reith, Christina, Emberson, Jonathan, Wheeler, David C., Tomson, Charles, Wanner, Christoph, Krane, Vera, Cass, Alan, Craig, Jonathan, Neal, Bruce, Jiang, Neal, Lixin, Hooi, Lai Seong, Levin, Adeera, Agodoa, Lawrence, Gaziano, Mike, Kasiske, Bertram, Walker, Robert, Massy, Ziad A., Feldt-Rasmussen, Bo, Krairittichai, Udon, Ophascharoensuk, Vuddidhej, Fellstrom, Bengt, Holdaas, Hallvard, Tesar, Viadimir, Wiecek, Andrzej, Grobbee, Diederick, de Zeeuw, Dick, Gronhagen-Riska, Carola ... Mudge, D. (2011). The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): A randomised placebo-controlled trial. Lancet, 377 (9784), 2181-2192. doi: 10.1016/S0140-6736(11)60739-3
2011
Journal Article
Do aluminium-based phosphate binders continue to have a role in contemporary nephrology practice?
Mudge, David W., Johnson, David W., Hawley, Carmel M., Campbell, Scott B., Isbel, Nicole M., van Eps, Carolyn L. and Petrie, James J. B. (2011). Do aluminium-based phosphate binders continue to have a role in contemporary nephrology practice?. BMC Nephrology, 12 (1) 20, 20.1-20.8. doi: 10.1186/1471-2369-12-20
2011
Book Chapter
Post-transplant anaemia
Bose, Bhadran and Mudge, David (2011). Post-transplant anaemia. After the kidney transplant - The patients and their allograft. (pp. 195-204) edited by Jorge Ortiz and Jason Andre. Croatia: Intech Open Access.
2011
Journal Article
Peritoneal dialysis practice in Australia and New Zealand: A call to action
Jose, M.D., Johnson, D.W., Mudge, D.W., Tranaeus, A., Voss, D., Walker, R. and Bannister, K.M. (2011). Peritoneal dialysis practice in Australia and New Zealand: A call to action. Nephrology, 16 (1), 19-29. doi: 10.1111/j.1440-1797.2010.01390.x
2010
Journal Article
Study of Heart and Renal Protection (SHARP): Randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease
Baigent, C., Landray, M., Reith, C., Dasgupta, T., Emberson, J., Herrington, W., Lewis, D., Mafham, M., Collins, R., Bray, C., Chen, Y., Baxter, A., Young, A., Hill, M., Knott, C., Cass, A., Feldt-Rasmussen, B., Fellström, B., Grobbee, R., Grönhagen-Riska, C., Haas, M., Holdaas, H., Hooi, L. S., Jiang, L., Kasiske, B., Krairittichai, U., Levin, A., Massy, Z., Tesar, V. ... Schenck, J. (2010). Study of Heart and Renal Protection (SHARP): Randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease. American Heart Journal, 160 (5), 785-794.e10. doi: 10.1016/j.ahj.2010.08.012
2010
Journal Article
The impact of extended-hours home hemodialysis and buttonhole cannulation technique on hospitalization rates for septic events related to dialysis access
Van Eps, CL, Jones, M, Ng, T, Johnson, DW, Campbell, SB, Isbel, NM, Mudge, DW, Beller, E and Hawley, CM (2010). The impact of extended-hours home hemodialysis and buttonhole cannulation technique on hospitalization rates for septic events related to dialysis access. Hemodialysis International, 14 (4), 451-463. doi: 10.1111/j.1542-4758.2010.00463.x
2010
Conference Publication
IMPROVED SEROCONVERSION WITH INTRADERMAL HEPATITIS B VACCINATION IN HAEMODIALYSIS PATIENTS NONRESPONSIVE TO INTRAMUSCULAR VACCINATION
Thirugnanasambanthan, T., Mills, K. and Mudge, D. (2010). IMPROVED SEROCONVERSION WITH INTRADERMAL HEPATITIS B VACCINATION IN HAEMODIALYSIS PATIENTS NONRESPONSIVE TO INTRAMUSCULAR VACCINATION. HOBOKEN: WILEY-BLACKWELL.
2010
Conference Publication
Dabigatran may not be an adequate anticoagulant for haemodialysis
Cho, Y., Mills, K., Sturtevant, J., Pillans, P. and Mudge, D. (2010). Dabigatran may not be an adequate anticoagulant for haemodialysis. 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA Australia, 12‐15 September 2010. Hoboken, NJ United States: Wiley-Blackwell.
2010
Journal Article
Dabigatran may not be an effective anticoagulant for haemodialysis
Cho, Y, Mills, K, Sturtevant, JM, Pillans, PI and Mudge, DW (2010). Dabigatran may not be an effective anticoagulant for haemodialysis. Nephrology, 15 (5), 594-595. doi: 10.1111/j.1440-1797.2010.01347.x
2010
Journal Article
Kidney transplantation without reversal of warfarin
Mudge, David W., Campbell, Scott B. and Ray, Mark (2010). Kidney transplantation without reversal of warfarin. Nephrology, Dialysis and Transplantation Plus, 3 (2), 170-171. doi: 10.1093/ndtplus/sfp150
2010
Conference Publication
Peritoneal dialysis practice in Australia and New Zealand: a call to action
Mudge, D., Jose, M., Johnson, D., Tranaeus, A., Voss, D., Walker, R. and Bannister, K. (2010). Peritoneal dialysis practice in Australia and New Zealand: a call to action. 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, Western Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell.
2010
Journal Article
Probable tacrolimus toxicity from tibolone co-administration in a woman: A case report
Clark, Carolyn J., Hawley, Carmel M. and Mudge, David W. (2010). Probable tacrolimus toxicity from tibolone co-administration in a woman: A case report. Journal of Medical Case Reports, 4 (1) 276, 276-1-276-4. doi: 10.1186/1752-1947-4-276
2010
Conference Publication
Outcome of Merkel cell carcinoma in renal transplant recipients
Sammartino, C., Edey, M., Barraclough, K., Bialasiewicz, S., Rockett, R., Sloots, T., Oliver, K., Strutton, G., Griffin, A., Campell, S., Mudge, D., Johnson, D. and Isbel, N. (2010). Outcome of Merkel cell carcinoma in renal transplant recipients. 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, Western Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell.
2010
Journal Article
Quality of life and alternate nightly nocturnal home hemodialysis
van Eps, Carolyn L., Jeffries, Janine K., Johnson, David W., Campbell, Scott B., Isbel, Nicole M., Mudge, David W. and Hawley, Carmel M. (2010). Quality of life and alternate nightly nocturnal home hemodialysis. Hemodialysis International, 14 (1), 29-38. doi: 10.1111/j.1542-4758.2009.00419.x
Funding
Past funding
Supervision
Availability
- Professor David Mudge is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Master Philosophy
Very early acute rejection in an Australian and New Zealand kidney transplant population
Principal Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley, Associate Professor Yeoung Jee Cho, Associate Professor Ross Francis
-
2015
Doctor Philosophy
Inflammation in Peritoneal Dialysis: Investigating the Roles of Biocompatible Solutions and Biological Markers
Associate Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley
Media
Enquiries
Contact Professor David Mudge directly for media enquiries about:
- Anaemia
- Chronic kidney disease
- Iron regulation
- Kidney disease
- Kidney transplantation
- Organ transplant - kidney
- Transplant - kidney
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