Overview
Background
My current appointment is Director of Kidney Services at Redland Hospitals in Metro South, Brisbane, where I practice as a senior consultant nephrologist.
My research interests are varied and include post-transplant anaemia and iron metabolism, and novel measures of iron status such as hepcidin; improving dialysis outcomes though the implementation of evidence-based guidelines; kidney disease due to thrombotic microangiopathy (particularly aHUS) and the role of inhibitors of the complement system in kidney disease; and the use of honey to prevent infections in dialysis patients.
I am committed to teaching medical students and young nephrologists, and am actively involved in medical education at all levels.
Availability
- Professor David Mudge is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine, of Surgery and of Obstetrics, The University of Queensland
- Doctoral (Research) of Medicine, The University of Queensland
Research impacts
The impact of my research in peritoneal dialysis has been a significant improvement in PD-related infection rates in Australia, which until a few years ago were worse than many other countries in the world. Through a variety of initiatives including a project aiming to improve the use of evidence-based guidelines in clinical practice, we have seen a significant improvement in PD-related infections (particularly peritonitis but also exit-site infections), one of the most significant contributors to peritoneal dialysis technique failure.
In kidney transplantation my research has helped to clarify the role of immune suppressing medications on iron availability and anaemia and has looked at novel ways of measuring iron status in patients with kidney disease as well as better ways of enhancing iron stores in these patients.
Works
Search Professor David Mudge’s works on UQ eSpace
2015
Journal Article
Pancreatic and biliary obstruction years after retention of a swallowed coin in a duodenal diverticulum: A case report
Ismail, Ibrahim and Mudge, David W (2015). Pancreatic and biliary obstruction years after retention of a swallowed coin in a duodenal diverticulum: A case report. Journal of Medical Case Reports, 9 (144) 144, 144. doi: 10.1186/s13256-015-0608-6
2015
Journal Article
The role of monitoring vancomycin levels in patients with peritoneal dialysis-associated peritonitis
Stevenson, Sarah, Tang, Wen, Cho, Yeoungjee, Mudge, David W., Hawley, Carmel M., Badve, Sunil V. and Johnson, David W. (2015). The role of monitoring vancomycin levels in patients with peritoneal dialysis-associated peritonitis. Peritoneal Dialysis International, 35 (2), 222-228. doi: 10.3747/pdi.2013.00156
2015
Journal Article
Altered dietary salt intake for people with chronic kidney disease (Review)
McMahon, Emma J., Campbell, Katrina L., Bauer, Judith D. and Mudge, David W. (2015). Altered dietary salt intake for people with chronic kidney disease (Review). Cochrane Database of Systematic Reviews, 2 (Art. No.: CD010070) CD010070. doi: 10.1002/14651858.CD010070.pub2
2015
Conference Publication
Chronic kidney disease is associated with progressive increase in arterial stiffness and bone-muscle loss over 1 year
Krishnasamy, R., Isbel, N. M., Johnson, D. W., Stanton, T., Fiumara, F., Bolwell, J., Vaneps, C., Mudge, D. W., Campbell, S., Tan, S. J., Toussaint, N. D. and Hawley, C. M. (2015). Chronic kidney disease is associated with progressive increase in arterial stiffness and bone-muscle loss over 1 year. 51st Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Canberra, Australia, 7-9 September 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12543
2014
Journal Article
A consensus statement on the renal monitoring of Australian patients receiving tenofovir based antiviral therapy for HIV/HBV infection
Holt, Stephen G., Gracey, David M., Levy, Miriam T., Mudge, David W., Irish, Ashley B., Walker, Rowan G., Baer, Richard, Sevastos, Jacob, Abbas, Riaz and Boyd, Mark A. (2014). A consensus statement on the renal monitoring of Australian patients receiving tenofovir based antiviral therapy for HIV/HBV infection. AIDS Research and Therapy, 11 (1) 35, 1-10. doi: 10.1186/1742-6405-11-35
2014
Conference Publication
RENAL FUNCTION TESTING IN PATIENTS ON TENOFOVIR ANTIVIRAL THERAPY
Holt, S. G., Gracey, D. M., Mudge, D. W., Irish, A. B., Sevastos, J., Walker, R. G., Baer, R. A., Levy, M. T. and Boyd, M. A. (2014). RENAL FUNCTION TESTING IN PATIENTS ON TENOFOVIR ANTIVIRAL THERAPY. HOBOKEN: WILEY-BLACKWELL.
2014
Journal Article
KHA-CARI guideline: Peritonitis treatment and prophylaxis
Walker, Amanda, Bannister, Kym, George, Charles, Mudge, David, Yehia, Maha, Lonergan, Maureen and Chow, Josephine (2014). KHA-CARI guideline: Peritonitis treatment and prophylaxis. Nephrology, 19 (2), 69-71. doi: 10.1111/nep.12152
2014
Conference Publication
Assessment of Current Practice and Barriers to Antimicrobial Prophylaxis in Peritoneal Dialysis Patients
Campbell, D. J., Brown, F., Craig, J., Gallagher, M., Johnson, D. W., Kirkland, G., Kumar, S. K., Lim, W. H., Ranganathan, D., Saweirs, W., Sud, K., Toussaint, N. D., Walker, R. G., Yehia, M. and Mudge, D. W. (2014). Assessment of Current Practice and Barriers to Antimicrobial Prophylaxis in Peritoneal Dialysis Patients. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, VIC Australia, 25 - 27 August 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301
2014
Journal Article
Erythropoiesis-stimulating agents for anaemia in chronic kidney disease: are they all the same?
Mudge, David W. and Webster, Angela C. (2014). Erythropoiesis-stimulating agents for anaemia in chronic kidney disease: are they all the same?. Cochrane Database of Systematic Reviews, 12 (12). doi: 10.1002/14651858.ED000093
2014
Book Chapter
Anaemia: prevalence, risk factors and management with a focus on chronic kidney disease
Abdul Razak, K., Mudge, D. W. and Johnson, D. W. (2014). Anaemia: prevalence, risk factors and management with a focus on chronic kidney disease. Anemia: prevalence, risk factors and management strategies. (pp. 123-146) Hauppauge, NY United States: Nova Science Publishers.
2014
Conference Publication
Volumetric bone mineral density (vBMD) and functional bone-muscle unit assessment with peripheral quantitative computed tomography(pQCT) in patients with chronic kidney disease (CKD) state 4 and 5
Krisnasamy, R., Isbel, N. M., Johnson, D. W., Campbell, S. B., Mudge, D. W., Van Eps, C. L., Fiumara, F., Bolwell, J., Stanton, T. and Hawley, C. M. (2014). Volumetric bone mineral density (vBMD) and functional bone-muscle unit assessment with peripheral quantitative computed tomography(pQCT) in patients with chronic kidney disease (CKD) state 4 and 5. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourme, VIC Australia, 25-27 August 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301
2013
Journal Article
Hydralazine-induced anti-neutrophil cytoplasmic antibody-positive renal vasculitis presenting with a vasculitic syndrome, acute nephritis and a puzzling skin rash: a case report
Keasberry, Justin K., Frazier, Jeremy, Isbel, Nicole M., van Eps, Carolyn L., Oliver, Kimberley and Mudge, David W. (2013). Hydralazine-induced anti-neutrophil cytoplasmic antibody-positive renal vasculitis presenting with a vasculitic syndrome, acute nephritis and a puzzling skin rash: a case report. Journal of Medical Case Reports, 7 (1) 20, 20.1-20.5. doi: 10.1186/1752-1947-7-20
2013
Book Chapter
Advances in antibody-mediated rejection
Sharma, Siddharth, Oliver, Kimberley and Mudge, David W. (2013). Advances in antibody-mediated rejection. Current issues and future direction in kidney transplantation. (pp. 445-462) edited by Thomas Rath. Rijeka, Croatia: InTech Open. doi: 10.5772/54855
2013
Conference Publication
Utility of "back up" arterio-venous fistulas in patients on peritoneal dialysis and use of central lines: A comparison between two Australian centres
Rao, N., Borlace, M., Taylor, R., Matthew, Y., Jaffrey, L., Johnson, D., Mudge, D. and Bannister, K. (2013). Utility of "back up" arterio-venous fistulas in patients on peritoneal dialysis and use of central lines: A comparison between two Australian centres. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell.
2013
Journal Article
Human SLC26A1 gene variants: a pilot study
Dawson, Paul A., Sim, Pearl, Mudge, David W. and Cowley, David (2013). Human SLC26A1 gene variants: a pilot study. Scientific World Journal, 2013 (1) 541710, 1-7. doi: 10.1155/2013/541710
2013
Conference Publication
Introducing Nxstage haemodialysis in the Australian home
Van Eps, C., Jeffires, J., Hawley, C., Johnson, D., Campbell, S., Isbel, N. and Mudge, D. (2013). Introducing Nxstage haemodialysis in the Australian home. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane Convention and Exhibition Centre, Brisbane, Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121
2012
Journal Article
A randomized controlled trial of oral heme iron polypeptide versus oral iron supplementation for the treatment of anaemia in peritoneal dialysis patients: HEMATOCRIT trial
Barraclough, Katherine A., Brown, Fiona, Hawley, Carmel M., Leary, Diana, Noble, Euan, Campbell, Scott B., Isbel, Nicole M., Mudge, David W., van Eps, Carolyn L. and Johnson, David W. (2012). A randomized controlled trial of oral heme iron polypeptide versus oral iron supplementation for the treatment of anaemia in peritoneal dialysis patients: HEMATOCRIT trial. Nephrology, Dialysis, Transplantation, 27 (11), 4146-4153. doi: 10.1093/ndt/gfs372
2012
Journal Article
[Withdrawn Publication] Interventions for post-transplant anaemia in kidney transplant recipients
Bose, Bhadran and Mudge, David W (2012). [Withdrawn Publication] Interventions for post-transplant anaemia in kidney transplant recipients. Cochrane Database of Systematic Reviews, 2020 (7) CD01011. doi: 10.1002/14651858.cd010113
2012
Journal Article
Altered dietary salt intake for chronic kidney disease (Protocol)
McMahon, Emma J., Campbell, Katrina L., Bauer, Judith D. and Mudge, David W. (2012). Altered dietary salt intake for chronic kidney disease (Protocol). Cochrane Database of Systematic Reviews (9 ). doi: 10.1002/14651858.CD010070
2012
Journal Article
A randomized controlled trial of intravenous or oral iron for posttransplant anemia in kidney transplantation
Mudge, David W., Tan, Ken-Soon, Miles, Rhianna, Johnson, David W., Badve, Sunil V., Campbell, Scott B., Isbel, Nicole M., van Eps, Carolyn L. and Hawley, Carmel M. (2012). A randomized controlled trial of intravenous or oral iron for posttransplant anemia in kidney transplantation. Transplantation, 93 (8), 822-826. doi: 10.1097/TP.0b013e318248375a
Funding
Past funding
Supervision
Availability
- Professor David Mudge is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Completed supervision
-
2019
Master Philosophy
Very early acute rejection in an Australian and New Zealand kidney transplant population
Principal Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley, Associate Professor Yeoung Jee Cho, Associate Professor Ross Francis
-
2015
Doctor Philosophy
Inflammation in Peritoneal Dialysis: Investigating the Roles of Biocompatible Solutions and Biological Markers
Associate Advisor
Other advisors: Professor David Johnson, Professor Carmel Hawley
Media
Enquiries
Contact Professor David Mudge directly for media enquiries about:
- Anaemia
- Chronic kidney disease
- Iron regulation
- Kidney disease
- Kidney transplantation
- Organ transplant - kidney
- Transplant - kidney
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: