Overview
Availability
- Dr Paul Clark is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, The University of Queensland
- Masters (Coursework) of Public Health and Tropical Medicine, James Cook University
- Doctor of Philosophy, University of New South Wales
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Works
Search Professor Paul Clark’s works on UQ eSpace
2014
Book Chapter
Hepatitis C Virus
Thompson, A. J., Clark, P. and Aghemo, A. (2014). Hepatitis C Virus. Handbook of Pharmacogenomics and Stratified Medicine. (pp. 859-877) edited by Sandosh Padmanabhan . London, UK: Academic Press. doi: 10.1016/B978-0-12-386882-4.00037-2
2013
Journal Article
Predictors of consent to pharmacogenomics testing in the IDEAL study
Jazwinski, Alison B., Clark, Paul J., Thompson, Alexander J., Gordon, Stuart C., Lawitz, Eric J., Noviello, Stephanie, Brass, Clifford A., Pedicone, Lisa D., Albrecht, Janice K., Sulkowski, Mark S. and Muir, Andrew J. (2013). Predictors of consent to pharmacogenomics testing in the IDEAL study. Pharmacogenetics and Genomics, 23 (11), 619-623. doi: 10.1097/FPC.0000000000000002
2013
Conference Publication
ITPA genotype predicts the development of on-treatment anaemia after 4 weeks of protease inhibitor therapy irrespective of fibrosis stage and past treatment experience status: A multi-centre real-life experience
Holmes, J. A., Mangia, A., Clark, P. J., Iser, D. M., Nguyen, T., Bell, S. J., Ryan, M., Bonanzinga, S., Desmond, P. V., Petruzzellis, D., Bowden, D. S. and Thompson, A. J. (2013). ITPA genotype predicts the development of on-treatment anaemia after 4 weeks of protease inhibitor therapy irrespective of fibrosis stage and past treatment experience status: A multi-centre real-life experience. HOBOKEN: WILEY-BLACKWELL.
2013
Conference Publication
ITPA ACTIVITY PREDICTS Hb DECLINE AFTER FOUR WEEKS OF PI TRIPLE THERAPY, REGARDLESS OF PREVIOUS TREATMENT OR NAIVE STATUS AND FIBROSIS: A MULTICENTER REAL-LIFE EXPERIENCE
Mangia, A., Clark, P. J., Piazzolla, V., Santoro, R., Holmes, J. A., Mottola, L., Ripoli, M., Iser, D., Nguyen, T., Bell, S. J., Desmond, P. V., Petruzzellis, D., Patel, K., Muir, A. J. and Thompson, A. J. (2013). ITPA ACTIVITY PREDICTS Hb DECLINE AFTER FOUR WEEKS OF PI TRIPLE THERAPY, REGARDLESS OF PREVIOUS TREATMENT OR NAIVE STATUS AND FIBROSIS: A MULTICENTER REAL-LIFE EXPERIENCE. International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Amsterdam Netherlands, Apr 24-28, 2013. AMSTERDAM: ELSEVIER SCIENCE BV.
2013
Journal Article
Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy
Clark, P. J., Aghemo, A., Degasperi, E., Galmozzi, E., Urban, T. J., Vock, D. M., Patel, K., Thompson, A. J., Rumi, M. G., D'Ambrosio, R., Muir, A. J. and Colombo, M. (2013). Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy. Journal of Viral Hepatitis, 20 (12), 858-866. doi: 10.1111/jvh.12113
2012
Journal Article
Search for anomalous production of prompt like-sign lepton pairs at √<i>s</i>=7 TeV with the ATLAS detector
Aad, G., Abajyan, T., Abbott, B., Abdallah, J., Khalek, S. Abdel, Abdelalim, A. A., Abdinov, O., Aben, R., Abi, B., Abolins, M., AbouZeid, O. S., Abramowicz, H., Abreu, H., Acerbi, E., Acharya, B. S., Adamczyk, L., Adams, D. L., Addy, T. N., Adelman, J., Adomeit, S., Adragna, P., Adye, T., Aefsky, S., Aguilar-Saavedra, J. A., Agustoni, M., Aharrouche, M., Ahlen, S. P., Ahles, F., Ahmad, A. ... Zwalinski, L. (2012). Search for anomalous production of prompt like-sign lepton pairs at √s=7 TeV with the ATLAS detector. Journal of High Energy Physics, 2012 (12) 007. doi: 10.1007/JHEP12(2012)007
2012
Journal Article
Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response
Naggie, Susanna, Osinusi, Anu, Katsounas, Antonios, Lempicki, Richard, Herrmann, Eva, Thompson, Alexander J., Clark, Paul J., Patel, Keyur, Muir, Andrew J., McHutchison, John G., Schlaak, Joerg F., Trippler, Martin, Shivakumar, Bhavana, Masur, Henry, Polis, Michael A. and Kottilil, Shyam (2012). Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response. Hepatology, 56 (2), 444-454. doi: 10.1002/hep.25647
2012
Journal Article
The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection (vol 57, pg 2213, 2012)
Clark, Paul J., Thompson, Alexander J., Zhu, Qianqian, Vock, David M., Zhu, Mingfu, Patel, Keyur, Harrison, Stephen A., Naggie, Susanna, Ge, Dongliang, Tillmann, Hans L., Urban, Thomas J., Shianna, Kevin, Fellay, Jacques, Goodman, Zachary, Noviello, Stephanie, Pedicone, Lisa D., Afdhal, Nezam, Sulkowski, Mark, Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection (vol 57, pg 2213, 2012). Digestive Diseases and Sciences, 57 (9), 2479-2479. doi: 10.1007/s10620-012-2309-y
2012
Journal Article
Overcoming Barriers to Care for Hepatitis C
Clark, Paul J. and Muir, Andrew J. (2012). Overcoming Barriers to Care for Hepatitis C. New England Journal of Medicine, 366 (26), 2436-2438. doi: 10.1056/NEJMp1202608
2012
Journal Article
Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response
Clark, P. J., Thompson, A. J., Zhu, M., Vock, D. M., Zhu, Q., Ge, D., Patel, K., Harrison, S. A., Urban, T. J., Naggie, S., Fellay, J., Tillmann, H. L., Shianna, K., Noviello, S., Pedicone, L. D., Esteban, R., Kwo, P., Sulkowski, M. S., Afdhal, N., Albrecht, J. K., Goldstein, D. B., McHutchison, J. G. and Muir, A. J. (2012). Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. Journal of Viral Hepatitis, 19 (5), 332-340. doi: 10.1111/j.1365-2893.2011.01553.x
2012
Conference Publication
Association of Serum Adipocytokines With IL28B and SVR in Chronic Hepatitis C
Clark, Paul J., Thompson, Alexander J., Jazwinski, Alison, Tillmann, Hans L., Naggie, Susanna, Muir, Andrew J. and Patel, Keyur (2012). Association of Serum Adipocytokines With IL28B and SVR in Chronic Hepatitis C. Digestive Disease Week (DDW), San Diego Ca, May 19-22, 2012. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2012
Journal Article
Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis
Jazwinski, A. B., Thompson, A. J., Clark, P. J., Naggie, S., Tillmann, H. L. and Patel, K. (2012). Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis. Journal of Viral Hepatitis, 19 (4), 278-282. doi: 10.1111/j.1365-2893.2011.01546.x
2012
Journal Article
Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?"
Thompson, A. J., Clark, P. J., Muir, A. J. and Sulkowski, M. S. (2012). Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?". Journal of Hepatology, 56 (3), 742-743. doi: 10.1016/j.jhep.2011.08.011
2012
Journal Article
Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients
Thompson, Alexander J., Clark, Paul J., Singh, Abanish, Ge, Dongliang, Fellay, Jacques, Zhu, Mingfu, Zhu, Qianqian, Urban, Thomas J., Patel, Keyur, Tillmann, Hans L., Naggie, Susanna, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric J., McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg W., King, John W., Kwo, Paul Y., Shianna, Kevin V., Noviello, Stephanie, Pedicone, Lisa D., Brass, Clifford A., Albrecht, Janice K., Sulkowski, Mark S., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. Journal of Hepatology, 56 (2), 313-319. doi: 10.1016/j.jhep.2011.04.021
2012
Journal Article
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes
Naggie, Susanna, Rallon, Norma I., Benito, Jose M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin V., Vispo, Eugenia, McHutchison, John G., Goldstein, David B. and Soriano, Vincent (2012). Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes. Journal of Infectious Diseases, 205 (3), 376-383. doi: 10.1093/infdis/jir754
2012
Journal Article
The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection
Clark, Paul J., Thompson, Alexander J., Zhu, Qianqian, Vock, David M., Zhu, Mingfu, Patel, Keyur, Harrison, Stephen A., Naggie, Susanna, Ge, Dongliang, Tillmann, Hans L., Urban, Thomas J., Shianna, Kevin, Fellay, Jacques, Goodman, Zachary, Noviello, Stephanie, Pedicone, Lisa D., Afdhal, Nezam, Sulkowski, Mark, Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection. Digestive Diseases and Sciences, 57 (8), 2213-2221. doi: 10.1007/s10620-012-2171-y
2012
Conference Publication
Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis C
Clark, Paul J., Santoro, Rosanna, Piazzolla, Valeria, Mottola, Leonardo, Bacca, D., Dello Iacono, N., Grimaldi, Salvatore, Quarta, Antonella, Urban, Thomas J., Naggie, Susanna, Patel, Keyur, Thompson, Alexander J., Muir, Andrew J. and Mangia, Alessandra (2012). Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis C. 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Ma, Nov 09-13, 2012. HOBOKEN: WILEY-BLACKWELL.
2012
Journal Article
Systemic thrombolysis for acute, severe Budd-Chiari syndrome
Clark, P.J., Slaughter, R.E. and Radford, D.J. (2012). Systemic thrombolysis for acute, severe Budd-Chiari syndrome. Journal of Thrombosis and Thrombolysis, 34 (3), 410-415. doi: 10.1007/s11239-012-0760-4
2012
Journal Article
Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner
Clark, Paul J., Thompson, Alexander J., Vock, David M., Kratz, Lisa E., Tolun, Adviye A., Muir, Andrew J., Mchutchison, John G., Subramanian, Mani, Millington, David M., Kelley, Richard I. and Patel, Keyur (2012). Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. Hepatology, 56 (1), 49-56. doi: 10.1002/hep.25631
2012
Conference Publication
Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin Support
Clark, P. J., Aghemo, A., Degasperi, E., Galmozzi, E., Thompson, A. J., Patel, K., Rumi, M. Grazia, Prati, G. M., Muir, A. J. and Colombo, M. (2012). Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin Support. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)61111-8
Funding
Current funding
Supervision
Availability
- Dr Paul Clark is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
-
Approaches to evaluating fibrosis and treating viral hepatitis remotely in regional Queensland
Supervision history
Current supervision
-
Doctor Philosophy
The role of the gut microbiome in alcohol related liver disease
Principal Advisor
Other advisors: Professor Jason Connor, Professor Gerald Holtmann
Completed supervision
-
2022
Doctor Philosophy
Epidemiology of viral hepatitis and liver diseases in migrant communities in Australia
Principal Advisor
Media
Enquiries
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