
Overview
Background
Prof Holtmann is a Clinical Academic in the field of Gastroenterology & Hepatology and Director of Clinical Innovation. He is also Director of the Department of Gastroenterology & Hepatology at the Princess Alexandra Hospital in Queensland and serves on the Board of Directors of the West Moreton Hospital and Health Service and UQ Healthcare. He is a Fellow of Royal Australian Collge of Physicians (RACP, Sydney), the Royal College of Physicians (RCP, London) and Fellow of the Australian Academy of Health and Medical Sciences (AAHMS, Canberra). Besides his Medical Qualifications he also obtained a Master of Business Administration. After completing the clinical training in Medicine and Gastroenterology at the University of Essen in Germany and the Mayo Clinic in Rochester, Minnesota in the United States, he has gained substantial leadership and managerial experience within the health care setting as Director of large Gastroenterology Departments, CEO and General Manager of a University Hospital and Health Care Facilities and has served on the Board of the University Hospital Essen in Germany. His research is in the field of Neurogastroenterology has resulted in peer reviewed publications in key journal including the NEJM, Lancet, Gastroenterology and Gut. More recently his rersearch focus is on the role of the gut microbiome, mucosal and systemic inflammation and brain-gut interactions.
Availability
- Professor Gerald Holtmann is:
- Available for supervision
- Media expert
Works
Search Professor Gerald Holtmann’s works on UQ eSpace
2025
Journal Article
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?
Lim, Yenkai, Kang, Seungha, Shah, Ayesha, Holtmann, Gerald and Morrison, Mark (2025). Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?. Gut, 74 (4), 692-693. doi: 10.1136/gutjnl-2024-334069
2025
Journal Article
Decoding the Gut-Brain Axis: A Journey Towards Targeted Interventions for Disorders-of-Gut-Brain Interaction
Holtmann, Gerald, Moniruzzaman, M D and Shah, Ayesha (2025). Decoding the Gut-Brain Axis: A Journey Towards Targeted Interventions for Disorders-of-Gut-Brain Interaction. Digestive diseases (Basel, Switzerland), 1-14. doi: 10.1159/000543845
2025
Journal Article
Small intestinal bacterial overgrowth in chronic liver disease: an updated systematic review and meta-analysis of case-control studies
Shah, Ayesha, Spannenburg, Liam, Thite, Parag, Morrison, Mark, Fairlie, Thomas, Koloski, Natasha, Kashyap, Purna C., Pimentel, Mark, Rezaie, Ali, Gores, Gregory J., Jones, Michael P. and Holtmann, Gerald (2025). Small intestinal bacterial overgrowth in chronic liver disease: an updated systematic review and meta-analysis of case-control studies. eClinicalMedicine, 80 103024, 103024-80. doi: 10.1016/j.eclinm.2024.103024
2025
Journal Article
Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies
Rubin, David T., Allegretti, Jessica R, Panés, Julián, Shipitofsky, Nicole, Yarandi, Shadi S, Huang, Kuan-Hsiang Gary, Germinaro, Matthew, Wilson, Rebbecca, Zhang, Hongyan, Johanns, Jewel, Feagan, Brian G, Hisamatsu, Tadakazu, Lichtenstein, Gary R, Bressler, Brian, Peyrin-Biroulet, Laurent, Sands, Bruce E, Dignass, Axel, Abrahamovych, Orest, Abu-Farsakh, Niazy, Afanasieva, Halyna, Akpinar, Hale, Kharrat, Houssam Al, Altintas, Engin, Altwegg, Romain, Andreev, Pavel, Aomatsu, Kazuki, Araki, Hiroshi, Argollo, Marjorie, Ariel, Federico ... Zureikat, Firas (2025). Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies. The Lancet, 405 (10472), 33-49. doi: 10.1016/S0140-6736(24)01927-5
2025
Journal Article
Economic evaluations of non-pharmacological interventions for treating disorders of gut-brain interaction: a scoping review
Pak, Anton, O'Grady, Madeline, Holtmann, Gerald, Shah, Ayesha and Tuffaha, Haitham (2025). Economic evaluations of non-pharmacological interventions for treating disorders of gut-brain interaction: a scoping review. PharmacoEconomics, 43 (3) e14578, 249-269. doi: 10.1007/s40273-024-01455-y
2024
Journal Article
A pathophysiologic framework for the overlap of disorders of gut-brain interaction and the role of the gut microbiome
Shah, Ayesha, Lee, Yeong Yeh, Suzuki, Hidekazu, Tan-Loh, Joash, Siah, Kewin Tien Ho, Gwee, Kok-Ann, Fairlie, Thomas, Talley, Nicholas J., Ghoshal, Uday C, Wang, Yen-Po, Kim, Yong Sung and Holtmann, Gerald (2024). A pathophysiologic framework for the overlap of disorders of gut-brain interaction and the role of the gut microbiome. Gut Microbes, 16 (1) 2413367, 1-16. doi: 10.1080/19490976.2024.2413367
2024
Journal Article
Post‐colonoscopy upper gastrointestinal malignancies in positive immunochemical fecal occult blood test patients: an Australian data linkage study
Pakneshan, Sahar, Moy, Naomi, Shah, Ayesha, Koloski, Natasha, Jones, Mike P., Talley, Nicholas J. and Holtmann, Gerald (2024). Post‐colonoscopy upper gastrointestinal malignancies in positive immunochemical fecal occult blood test patients: an Australian data linkage study. Journal of Gastroenterology and Hepatology, 39 (12), 2811-2816. doi: 10.1111/jgh.16799
2024
Conference Publication
Small intestinal bacterial overgrowth as assessed by breath testing: a prospective evaluation against the 'gold standard' small bowel aspirate and culture
Hansen, Teressa, Shah, Ayesha, Fairlie, Tom, Koloski, Natasha, Jones, Michael, Morrion, Mark and Holtmann, Gerald (2024). Small intestinal bacterial overgrowth as assessed by breath testing: a prospective evaluation against the 'gold standard' small bowel aspirate and culture. 5th Meeting of the Federation of Neurogastroenterology and Motility (FNM 2024), Bangkok, Thailand, 6 - 8 November 2024. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.
2024
Conference Publication
Oral contraceptives are strongly associated with an increased risk of irritable bowel syndrome but not functional dyspepsia among women in primary care
Koloski, Natasha, Jones, Michael, Shah, Ayesha, Holtmann, Gerald and Talley, Nicholas (2024). Oral contraceptives are strongly associated with an increased risk of irritable bowel syndrome but not functional dyspepsia among women in primary care. 5th Meeting of the Federation of Neurogastroenterology and Motility (FNM 2024), Bangkok, Thailand, 6 - 8 November 2024. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/nmo.14902
2024
Journal Article
Costs and benefits of a formal quality framework for colonoscopy: economic evaluation
Pakneshan, Sahar, Moy, Naomi, O'Connor, Sam, Hourigan, Luke, Messmann, Helmut, Shah, Ayesha, Dulleck, Uwe and Holtmann, G.J. (2024). Costs and benefits of a formal quality framework for colonoscopy: economic evaluation. Endoscopy International Open, 12 (11), E1334-E1341. doi: 10.1055/a-2444-6292
2024
Conference Publication
Psychological distress does not explain the association between some disorders of gut brain interaction and eating disorders among primary care patients
Koloski, Natasha, Jones, Michael, Shah, Ayesha, Holtmann, Gerald and Talley, Nicholas (2024). Psychological distress does not explain the association between some disorders of gut brain interaction and eating disorders among primary care patients. 5th Meeting of the Federation of Neurogastroenterology and Motility (FNM 2024), Bangkok, Thailand, 6 - 8 November 2024. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.
2024
Journal Article
Diagnostic classification systems for disorders of gut‐brain interaction should include psychological symptoms
Jones, Michael P., Holtmann, Gerald J., Tack, Jan, Carbonne, Florencia, Chey, William, Koloski, Natasha, Shah, Ayesha, Bangdiwala, Shrikant I., Sperber, Ami D., Palsson, Olafur S. and Talley, Nicholas J. (2024). Diagnostic classification systems for disorders of gut‐brain interaction should include psychological symptoms. Neurogastroenterology & Motility, 36 (12) e14940. doi: 10.1111/nmo.14940
2024
Journal Article
The biogeography of the mucosa-associated microbiome in health and disease
Sternes, Peter R., Shah, Ayesha, Ayala Pintos, Camila, Fairlie, Thomas, Koloski, Natasha, Kang, Seungha, Tousignant, Kaylyn D., McIlroy, Simon J., Morrison, Mark, Tyson, Gene W. and Holtmann, Gerald J. (2024). The biogeography of the mucosa-associated microbiome in health and disease. Frontiers in Microbiology, 15 1454910, 1-14. doi: 10.3389/fmicb.2024.1454910
2024
Conference Publication
Small intestinal bacterial overgrowth as assessed by breath testing: a prospective evaluation to the gold standard aspirate
Shah, Ayesha, Hansen, Teressa, Fairlie, Thomas, Koloski, Natasha, Jones, Mike and Holtmann, Gerald (2024). Small intestinal bacterial overgrowth as assessed by breath testing: a prospective evaluation to the gold standard aspirate. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.
2024
Conference Publication
Value based assessment of same day upper and lower endoscopy for patients referred for colonoscopy with a positive immunochemical feacal occult blood test
Shah, Ayesha, Moy, Naomi, Whaley, Amanda, Hansen, Teressa, Virgo, Kate, Dulleck, Uwe, Koloski, Natasha, Jones, Mike and Holtmann, Gerald (2024). Value based assessment of same day upper and lower endoscopy for patients referred for colonoscopy with a positive immunochemical feacal occult blood test. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.
2024
Conference Publication
Simethicone suppresses the growth of microbes cultured from the human duodenal mucosa
Fairlie, Thomas, Shah, Ayesha, Lim, Yenkai, Teh, Jing-Jie, Schooth, Lauren, Morrison, Mark and Holtmann, Gerald (2024). Simethicone suppresses the growth of microbes cultured from the human duodenal mucosa. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.
2024
Conference Publication
The duodenal mucosa-associated microbiota differs in patients based on their Rome IV classification, and has variable effects on duodenal spheroid barrier function subjects
Schooth, Lauren, Burns, Grace, Minahan, Kyra, Teh, Jing-Jie, Fairlie, Tom, Shah, Ayesha, Holtmann, Gerald and Morrison, Mark (2024). The duodenal mucosa-associated microbiota differs in patients based on their Rome IV classification, and has variable effects on duodenal spheroid barrier function subjects. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.
2024
Journal Article
A multifaceted ecological approach to explore links between environmental factors and the epidemiology of disorders of gut–brain interaction
Fairlie, Thomas, Shah, Ayesha, Wong, Reuben K., Fang, Xiucai, Ghoshal, Uday C., Kashyap, Purna C., Mulak, Agata, Lee, Yeong Yeh, Sperber, Ami D., Koloski, Natasha, Moy, Naomi, Talley, Nicholas J., Jones, Michael P. and Holtmann, Gerald (2024). A multifaceted ecological approach to explore links between environmental factors and the epidemiology of disorders of gut–brain interaction. Neurogastroenterology and Motility, 36 (9) e14866, 1-13. doi: 10.1111/nmo.14866
2024
Conference Publication
Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis
Khoo, Emi, Amiss, Anna, Lindsay, Niamh, Fernandes, Richard, Gilmore, Robert, Ding, John Nik, Connor, Susan J., Bryant, Robert, White, Lauren, Mohsen, Waled, Leong, Rupert, Ardalan, Zaid, Croft, Anthony, De Cruz, Peter, Lynch, Kate, An, Yoon-Kyo, Holtmann, Gerald and Begun, Jakob (2024). Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.
2024
Conference Publication
The biogeography of the mucosa-associated microbiota is associated with the presence and symptom severity of inflammatory bowel disease, proton pump inhibitor usage, and visceral sensitivity
Sternes, Peter, Shah, Ayesha, Pintos, Camila Ayela, Fairlie, Thomas, Koloski, Natasha, Kang, Seungha, Mcilroy, Simon, Morrison, Mark, Tyson, Gene and Holtmann, Gerald (2024). The biogeography of the mucosa-associated microbiota is associated with the presence and symptom severity of inflammatory bowel disease, proton pump inhibitor usage, and visceral sensitivity. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2024, Adelaide, SA Australia, 14-16 September 2024. Richmond, VIC Australia: John Wiley & Sons.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Gerald Holtmann is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective
Principal Advisor
Other advisors: Dr Ayesha Shah
-
Doctor Philosophy
IBD and mental health tools: a holistic approach to discovery and appropriate tool.
Principal Advisor
Other advisors: Dr Ayesha Shah
-
Doctor Philosophy
Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions
Principal Advisor
Other advisors: Dr Ayesha Shah
-
Doctor Philosophy
Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions
Principal Advisor
Other advisors: Dr Ayesha Shah
-
Doctor Philosophy
Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective.
Principal Advisor
Other advisors: Dr Ayesha Shah
-
Doctor Philosophy
Equitability and Accessibility of Faecal Occult Blood Test Based Colorectal Cancer Screening for Disadvantaged Communities.
Principal Advisor
-
Doctor Philosophy
The role of the gut microbiome in alcohol related liver disease
Associate Advisor
Other advisors: Professor Jason Connor, Dr Paul Clark
-
Doctor Philosophy
Study of TOfacitinib for the treatment of chronic Pouchitis
Associate Advisor
Other advisors: Associate Professor Jakob Begun
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Doctor Philosophy
Study of TOfacitinib for the treatment of chronic Pouchitis
Associate Advisor
Other advisors: Associate Professor Jakob Begun
-
Doctor Philosophy
Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.
Associate Advisor
Other advisors: Professor Jeff Coombes
Completed supervision
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2020
Doctor Philosophy
Characterization of the Human Duodenal Microbiome in Health and Disease
Principal Advisor
Other advisors: Associate Professor Graeme Macdonald
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2019
Doctor Philosophy
Mechanisms of action of the duodenal-jejunal bypass sleeve
Principal Advisor
Other advisors: Associate Professor Graeme Macdonald
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2023
Doctor Philosophy
Structure-function relationships of the mucosa-associated microbiota in Crohn's disease
Associate Advisor
Other advisors: Associate Professor Jakob Begun, Professor Mark Morrison
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2022
Doctor Philosophy
Genomic- and culture-enabled analyses of host-associated methanogenic archaea
Associate Advisor
Other advisors: Professor Mark Morrison
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2022
Doctor Philosophy
Multi-omics data offer systemic insights into autism
Associate Advisor
Other advisors: Professor Naomi Wray, Honorary Professor Jake Gratten
-
Doctor Philosophy
The role of small intestinal permeability and gut microbiota in chronic liver disease
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
Media
Enquiries
Contact Professor Gerald Holtmann directly for media enquiries about:
- colon cancer screening
- Gastroenterology
- Gut Health
- Microbiome
- Neurogastroenterology
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