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Professor Gerald Holtmann
Professor

Gerald Holtmann

Email: 
Phone: 
+61 7 3176 7792

Overview

Background

Prof Holtmann is a Clinical Academic in the field of Gastroenterology & Hepatology and Director of Clinical Innovation. He is also Director of the Department of Gastroenterology & Hepatology at the Princess Alexandra Hospital in Queensland and serves on the Board of Directors of the West Moreton Hospital and Health Service and UQ Healthcare. He is a Fellow of Royal Australian Collge of Physicians (RACP, Sydney), the Royal College of Physicians (RCP, London) and Fellow of the Australian Academy of Health and Medical Sciences (AAHMS, Canberra). Besides his Medical Qualifications he also obtained a Master of Business Administration. After completing the clinical training in Medicine and Gastroenterology at the University of Essen in Germany and the Mayo Clinic in Rochester, Minnesota in the United States, he has gained substantial leadership and managerial experience within the health care setting as Director of large Gastroenterology Departments, CEO and General Manager of a University Hospital and Health Care Facilities and has served on the Board of the University Hospital Essen in Germany. His research is in the field of Neurogastroenterology has resulted in peer reviewed publications in key journal including the NEJM, Lancet, Gastroenterology and Gut. More recently his rersearch focus is on the role of the gut microbiome, mucosal and systemic inflammation and brain-gut interactions.

Availability

Professor Gerald Holtmann is:
Available for supervision
Media expert

Works

Search Professor Gerald Holtmann’s works on UQ eSpace

518 works between 1986 and 2024

21 - 40 of 518 works

2024

Conference Publication

Small Intestinal Bacterial Overgrowth In Chronic Liver Disease: An Updated Systematic Review And Meta-analysis Of Case-control Studies

Shah, Ayesha, Spannenburg, Liam, Thite, Parag, Fairlie, Thomas, Koloski, Natasha A., Morrison, Mark, Jones, Michael P. and Holtmann, Gerald J. (2024). Small Intestinal Bacterial Overgrowth In Chronic Liver Disease: An Updated Systematic Review And Meta-analysis Of Case-control Studies. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)02706-9

Small Intestinal Bacterial Overgrowth In Chronic Liver Disease: An Updated Systematic Review And Meta-analysis Of Case-control Studies

2024

Conference Publication

Diagnostic Classification Systems For Disorders Of Gut-brain Interaction Should Include Psychological Symptoms

Jones, Michael P., Holtmann, Gerald J., Tack, Jan F., Carbone, Florencia, Chey, William D., Koloski, Natasha A., Shah, Ayesha, Bangdiwala, Shrikant I., Sperber, Ami D., Palsson, Olafur S. and Talley, Nicholas J. (2024). Diagnostic Classification Systems For Disorders Of Gut-brain Interaction Should Include Psychological Symptoms. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)01601-9

Diagnostic Classification Systems For Disorders Of Gut-brain Interaction Should Include Psychological Symptoms

2024

Conference Publication

The Duodenal Mucosa-associated Microbiota Of Patients With A Disorder Of Gut-brain Interaction Can Be Differentiated By Rome IV Criteria

Schooth, Lauren F., Kang, Seungha, Fairlie, Thomas, Lim, Yenkai, Teh, Jing Jie, Hoedt, Emily C., Keely, Simon, Shah, Ayesha, Holtmann, Gerald J. and Morrison, Mark (2024). The Duodenal Mucosa-associated Microbiota Of Patients With A Disorder Of Gut-brain Interaction Can Be Differentiated By Rome IV Criteria. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)02266-2

The Duodenal Mucosa-associated Microbiota Of Patients With A Disorder Of Gut-brain Interaction Can Be Differentiated By Rome IV Criteria

2024

Journal Article

Double‐blind, randomized, 8‐week multicenter study of the efficacy and safety of <scp>STW 5‐II</scp><i>versus</i> placebo in functional dyspepsia

Vinson, Bettina, Fink, Careen, Wargenau, Manfred, Talley, Nicholas J and Holtmann, Gerald (2024). Double‐blind, randomized, 8‐week multicenter study of the efficacy and safety of STW 5‐IIversus placebo in functional dyspepsia. JGH Open, 8 (5) e13054, e13054. doi: 10.1002/jgh3.13054

Double‐blind, randomized, 8‐week multicenter study of the efficacy and safety of <scp>STW 5‐II</scp><i>versus</i> placebo in functional dyspepsia

2024

Conference Publication

A Multifaceted Ecological Approach To Explore Links Between Environmental Factors And The Epidemiology Of Disorders Of Gut-brain Interaction

Fairlie, Thomas, Shah, Ayesha, Koloski, Natasha A., Moy, Naomi, Wong, Reuben K., Fang, Xiucai, Ghoshal, Uday C., Kashyap, Purna, Mulak, Agata, Lee, Yeong Yeh, Sperber, Ami D., Jones, Michael P. and Holtmann, Gerald J. (2024). A Multifaceted Ecological Approach To Explore Links Between Environmental Factors And The Epidemiology Of Disorders Of Gut-brain Interaction. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)03274-8

A Multifaceted Ecological Approach To Explore Links Between Environmental Factors And The Epidemiology Of Disorders Of Gut-brain Interaction

2024

Conference Publication

A Minority With Childhood Disorders Of Gut-brain Interactions Continue In Adulthood, But Mood Disorders Increase The Odds Of Childhood Gastrointestinal Symptoms Persisting Into Adulthood

Jones, Michael P., Koloski, Natasha A., Walker, Marjorie M., Holtmann, Gerald J., Shah, Ayesha, Eslick, Guy D. and Talley, Nicholas J. (2024). A Minority With Childhood Disorders Of Gut-brain Interactions Continue In Adulthood, But Mood Disorders Increase The Odds Of Childhood Gastrointestinal Symptoms Persisting Into Adulthood. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)01049-7

A Minority With Childhood Disorders Of Gut-brain Interactions Continue In Adulthood, But Mood Disorders Increase The Odds Of Childhood Gastrointestinal Symptoms Persisting Into Adulthood

2024

Conference Publication

A Novel Isolate Of Streptococcus Salivarius, AGIRA0003, Disrupts Tight Junctions Ex Vivo In Functional Dyspepsia

Burns, Grace L., Wark, Jasmine A., Hoedt, Emily C., Minahan, Kyra, Sherwin, Simonne, Bruce, Jessica K., Lim, Yenkai, Teh, Jing Jie, Jamaluddin, M. Fairuz, Soh, Wai Sinn, Caban, Shandelle, Almazi, Juhura, Woldu, Ameha S., Dun, Matthew D., Potter, Michael D., Shanahan, Erin R., Holtmann, Gerald J., Walker, Marjorie M., Morrison, Mark, Talley, Nicholas J. and Keely, Simon (2024). A Novel Isolate Of Streptococcus Salivarius, AGIRA0003, Disrupts Tight Junctions Ex Vivo In Functional Dyspepsia. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)02260-1

A Novel Isolate Of Streptococcus Salivarius, AGIRA0003, Disrupts Tight Junctions Ex Vivo In Functional Dyspepsia

2024

Journal Article

Editorial: Is it time to include oral vancomycin in therapeutic guidelines for primary sclerosing cholangitis‐associated inflammatory bowel disease?

Shah, Ayesha and Holtmann, Gerald (2024). Editorial: Is it time to include oral vancomycin in therapeutic guidelines for primary sclerosing cholangitis‐associated inflammatory bowel disease?. Alimentary Pharmacology & Therapeutics, 59 (10), 1290-1291. doi: 10.1111/apt.17990

Editorial: Is it time to include oral vancomycin in therapeutic guidelines for primary sclerosing cholangitis‐associated inflammatory bowel disease?

2024

Journal Article

A Minority of Childhood Disorders of Gut-Brain Interaction Persist Into Adulthood: A Risk-Factor Analysis

Jones, Michael P., Koloski, Natasha A., Walker, Marjorie M., Holtmann, Gerald J., Shah, Ayesha, Eslick, Guy D. and Talley, Nicholas J. (2024). A Minority of Childhood Disorders of Gut-Brain Interaction Persist Into Adulthood: A Risk-Factor Analysis. American Journal of Gastroenterology, 119 (9), 1-7. doi: 10.14309/ajg.0000000000002751

A Minority of Childhood Disorders of Gut-Brain Interaction Persist Into Adulthood: A Risk-Factor Analysis

2024

Journal Article

What impact has the Centre of Research Excellence in Digestive Health made in the field of gastrointestinal health in Australia and internationally? Study protocol for impact evaluation using the FAIT framework

Koloski, Natasha, Duncanson, Kerith, Ramanathan, Shanthi Ann, Rao, Melanie, Holtmann, Gerald and Talley, Nicholas J (2024). What impact has the Centre of Research Excellence in Digestive Health made in the field of gastrointestinal health in Australia and internationally? Study protocol for impact evaluation using the FAIT framework. BMJ Open, 14 (3) e076839, 1-8. doi: 10.1136/bmjopen-2023-076839

What impact has the Centre of Research Excellence in Digestive Health made in the field of gastrointestinal health in Australia and internationally? Study protocol for impact evaluation using the FAIT framework

2024

Journal Article

Healthcare Utilization Patterns: Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Gastroesophageal Reflux Disease

Koloski, Natasha, Shah, Ayesha, Kaan, Iain, Ben Jacob, Ronen, Talley, Nicholas J., Jones, Michael P. and Holtmann, Gerald (2024). Healthcare Utilization Patterns: Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Gastroesophageal Reflux Disease. Digestive Diseases and Sciences, 69 (5), 1626-1635. doi: 10.1007/s10620-024-08297-w

Healthcare Utilization Patterns: Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Gastroesophageal Reflux Disease

2024

Journal Article

Cost-effectiveness of taurolidine-citrate in a cohort of patients with intestinal failure receiving home parenteral nutrition

Williams, Thomas J., Moy, Naomi, Kaazan, Patricia, Callaghan, Gavin, Holtmann, Gerald and Martin, Neal (2024). Cost-effectiveness of taurolidine-citrate in a cohort of patients with intestinal failure receiving home parenteral nutrition. Journal of Parenteral and Enteral Nutrition, 48 (2), 165-173. doi: 10.1002/jpen.2589

Cost-effectiveness of taurolidine-citrate in a cohort of patients with intestinal failure receiving home parenteral nutrition

2024

Journal Article

Efficacy and Safety of STW 5-II for Functional Dyspepsia Treatment: A Patient Data-Based Meta-Analysis

Andresen, Viola, Shah, Ayesha, Fink, Careen, Rabini, Sabine, Wargenau, Manfred and Holtmann, Gerald (2024). Efficacy and Safety of STW 5-II for Functional Dyspepsia Treatment: A Patient Data-Based Meta-Analysis. Digestion, 105 (3), 166-174. doi: 10.1159/000535672

Efficacy and Safety of STW 5-II for Functional Dyspepsia Treatment: A Patient Data-Based Meta-Analysis

2024

Journal Article

Erratum: Autism-related dietary preferences mediate autism-gut microbiome associations (Cell (2021) 184(24) (5916–5931.e17), (S0092867421012319), (10.1016/j.cell.2021.10.015))

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2024). Erratum: Autism-related dietary preferences mediate autism-gut microbiome associations (Cell (2021) 184(24) (5916–5931.e17), (S0092867421012319), (10.1016/j.cell.2021.10.015)). Cell, 187 (2), 495-510. doi: 10.1016/j.cell.2023.12.001

Erratum: Autism-related dietary preferences mediate autism-gut microbiome associations (Cell (2021) 184(24) (5916–5931.e17), (S0092867421012319), (10.1016/j.cell.2021.10.015))

2024

Conference Publication

Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis

Khoo, E., Amiss, A., Ding, J. N., Bryant, R., Mohsen, W., Connor, S., Leung, R., Croft, A., Lynch, K., Sparrow, M., De Cruz, P., An, Y. K., Holtmann, G. and Begun, J. (2024). Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis. 19th Congress of ECCO, Stockholm, Sweden, 21-24 February 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjad212.0984

Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis

2024

Journal Article

Preinjection With Ligation-Assisted Endoscopic Mucosal Resection for Barrett's Dysplasia and Early Esophageal Adenocarcinoma: Characteristic Histological Features of the Depth of Resection

Williams, Thomas J., Hlaing, Phyu, Maher, Adrian M., Walker, Neal, Kendall, Bradley J., Holtmann, Gerald and Hourigan, Luke F. (2024). Preinjection With Ligation-Assisted Endoscopic Mucosal Resection for Barrett's Dysplasia and Early Esophageal Adenocarcinoma: Characteristic Histological Features of the Depth of Resection. Journal of Clinical Gastroenterology 2026. doi: 10.1097/MCG.0000000000002026

Preinjection With Ligation-Assisted Endoscopic Mucosal Resection for Barrett's Dysplasia and Early Esophageal Adenocarcinoma: Characteristic Histological Features of the Depth of Resection

2024

Journal Article

Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis

Shah, Ayesha, Jones, Michael P., Callaghan, Gavin, Fairlie, Thomas, Ma, Xiaomin, Culver, Emma L., Stuart, Katherine, De Cruz, Peter, O’Beirne, James, Tabibian, James H., Dignass, Axel, Canbay, Ali, Gores, Gregory J. and Holtmann, Gerald J. (2024). Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis. Hepatology Communications, 8 (1) e0347. doi: 10.1097/hc9.0000000000000347

Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis

2024

Conference Publication

Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis

Khoo, E., Amiss, A., Ding, J. N., Bryant, R., Mohsen, W., Connor, S., Leung, R., Croft, A., Lynch, K., Sparrow, M., De Cruz, P., An, Y. K., Holtmann, G. and Begun, J. (2024). Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis. 19th Congress of ECCO, Stockholm, Sweden, 21-24 February 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjad212.0984

Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis

2023

Journal Article

TRAV26-2 T cell receptor expression is associated with mucosal lymphocyte response to wheat proteins in functional dyspepsia patients

Burns, Grace L., Potter, Michael, Mathe, Andrea, Bruce, Jessica, Minahan, Kyra, Barnes, Jessica L., Pryor, Jennifer, Nieva, Cheenie, Sherwin, Simonne, Cuskelly, Annalisa, Fairlie, Thomas, Cameron, Raquel, Bollipo, Steven, Irani, Mudar Zand, Foster, Robert, Gan, Lay T., Shah, Ayesha, Koloski, Natasha, Foster, Paul S., Horvat, Jay C., Walker, Marjorie M., Powell, Nick, Veysey, Martin, Duncanson, Kerith, Holtmann, Gerald, Talley, Nicholas J. and Keely, Simon (2023). TRAV26-2 T cell receptor expression is associated with mucosal lymphocyte response to wheat proteins in functional dyspepsia patients. Clinical and Translational Gastroenterology, 14 (12) e00638, e00638. doi: 10.14309/ctg.0000000000000638

TRAV26-2 T cell receptor expression is associated with mucosal lymphocyte response to wheat proteins in functional dyspepsia patients

2023

Conference Publication

Small intestinal bacterial overgrowth in chronic liver disease: a systematic review and meta-analysis of case-control studies

Spannenburg, L., Shah, A., Thite, P., Fairlie, T., Moniruzzaman, M., Stuart, K. A., Koloski, N. A., Morrison, M., Jones, M. P. and Holtmann, G. J. (2023). Small intestinal bacterial overgrowth in chronic liver disease: a systematic review and meta-analysis of case-control studies. 31st United European Gastroenterology Week 2023, Copenhagen, Denmark, 14-17 October 2023. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/ueg2.1246

Small intestinal bacterial overgrowth in chronic liver disease: a systematic review and meta-analysis of case-control studies

Funding

Current funding

  • 2022 - 2026
    ARC Training Centre for Behavioural Insights for Technology Adoption (BITA) (ARC Industrial Transformation Training Centre Administered by QUT)
    Queensland University of Technology
    Open grant
  • 2021 - 2025
    A practice change for patients with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled intervention to assess efficacy and cost-effectiveness
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2025
    Targeting the gut microbiome as a treatment for Primary Sclerosing Cholangitis: The Queensland Clinical Network Study
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant

Past funding

  • 2020 - 2024
    Modulation of the Gastrointestinal Microbiome with probiotics and subsequent Methane production as a novel approach to treat constipation: A Proof of Principle Study (TRI Sport Grant led by PAH)
    Metro South Hospital and Health Service
    Open grant
  • 2019 - 2024
    Centre for Research Excellence in Digestive Health (NHMRC CRE administered by University of Newcastle)
    University of Newcastle
    Open grant
  • 2016
    Establishing a gnotobiotic germ-free mouse facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    The Australian human microbiota project-microbe isolation facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Pathophysiology of functional dyspepsia: Integration of upper gut function, inflammation and a systems biology approach.
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy (NHMRC Project Grant administered by the University of Newcastle)
    University of Newcastle
    Open grant

Supervision

Availability

Professor Gerald Holtmann is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Equitability and Accessibility of Faecal Occult Blood Test Based Colorectal Cancer Screening for Disadvantaged Communities.

    Principal Advisor

  • Doctor Philosophy

    Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective

    Principal Advisor

  • Doctor Philosophy

    Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.

    Associate Advisor

    Other advisors: Professor Jeff Coombes

  • Doctor Philosophy

    The role of the gut microbiome in alcohol related liver disease

    Associate Advisor

    Other advisors: Professor Jason Connor, Dr Paul Clark

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

Completed supervision

Media

Enquiries

Contact Professor Gerald Holtmann directly for media enquiries about:

  • colon cancer screening
  • Gastroenterology
  • Gut Health
  • Microbiome
  • Neurogastroenterology

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au