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Professor Gerald Holtmann
Professor

Gerald Holtmann

Email: 
Phone: 
+61 7 3176 7792

Overview

Background

Prof Holtmann is a Clinical Academic in the field of Gastroenterology & Hepatology and Director of Clinical Innovation. He is also Director of the Department of Gastroenterology & Hepatology at the Princess Alexandra Hospital in Queensland and serves on the Board of Directors of the West Moreton Hospital and Health Service and UQ Healthcare. He is a Fellow of Royal Australian Collge of Physicians (RACP, Sydney), the Royal College of Physicians (RCP, London) and Fellow of the Australian Academy of Health and Medical Sciences (AAHMS, Canberra). Besides his Medical Qualifications he also obtained a Master of Business Administration. After completing the clinical training in Medicine and Gastroenterology at the University of Essen in Germany and the Mayo Clinic in Rochester, Minnesota in the United States, he has gained substantial leadership and managerial experience within the health care setting as Director of large Gastroenterology Departments, CEO and General Manager of a University Hospital and Health Care Facilities and has served on the Board of the University Hospital Essen in Germany. His research is in the field of Neurogastroenterology has resulted in peer reviewed publications in key journal including the NEJM, Lancet, Gastroenterology and Gut. More recently his rersearch focus is on the role of the gut microbiome, mucosal and systemic inflammation and brain-gut interactions.

Availability

Professor Gerald Holtmann is:
Available for supervision
Media expert

Works

Search Professor Gerald Holtmann’s works on UQ eSpace

531 works between 1986 and 2025

81 - 100 of 531 works

2023

Journal Article

Small intestinal bacterial overgrowth complicating gastrointestinal manifestations of systemic sclerosis: a systematic review and meta-analysis

Shah, Ayesha, Pakeerathan, Veenaa, Jones, Michael P., Kashyap, Purna C., Virgo, Kate, Fairlie, Thomas, Morrison, Mark, Ghoshal, Uday C. and Holtmann, Gerald J. (2023). Small intestinal bacterial overgrowth complicating gastrointestinal manifestations of systemic sclerosis: a systematic review and meta-analysis. Journal of Neurogastroenterology and Motility, 29 (2), 132-144. doi: 10.5056/jnm22168

Small intestinal bacterial overgrowth complicating gastrointestinal manifestations of systemic sclerosis: a systematic review and meta-analysis

2023

Journal Article

Evaluation of small intestinal bacterial overgrowth

Ghoshal, Uday C, Ghoshal, Ujjala, Shah, Ayesha and Holtmann, Gerald (2023). Evaluation of small intestinal bacterial overgrowth. Expert Review of Gastroenterology and Hepatology, 17 (5), 461-467. doi: 10.1080/17474124.2023.2207008

Evaluation of small intestinal bacterial overgrowth

2023

Journal Article

Social determinants and participation in fecal occult blood test based colorectal cancer screening: A qualitative systematic review and meta-synthesis

Marinucci, Nicole, Moy, Naomi, Koloski, Natasha, Shah, Ayesha, Austin, Glenn, Russell‐Bennett, Rebekah, McGraw, Jacquie, Dulleck, Uwe and Holtmann, Gerald (2023). Social determinants and participation in fecal occult blood test based colorectal cancer screening: A qualitative systematic review and meta-synthesis. Health Promotion Journal of Australia, 35 (1), 9-36. doi: 10.1002/hpja.732

Social determinants and participation in fecal occult blood test based colorectal cancer screening: A qualitative systematic review and meta-synthesis

2023

Journal Article

Asia‐Pacific Guidelines for Managing Functional Dyspepsia Overlapping with Other Gastrointestinal Symptoms

Gwee, Kok‐Ann, Lee, Yeong Yeh, Suzuki, Hidekazu, Ghoshal, Uday Chand, Holtmann, Gerald, Bai, Tao, Barbara, Giovanni, Chen, Min‐hu, Chua, Andrew Seng Boon, Gibson, Peter R., Hou, Xiaohua, Liu, Jinsong, Nakajima, Atsushi, Pratap, Nitesh, Sachdeva, Sanjeev, Siah, Kewin Tien Ho, Soh, Alex Yu Sen, Sugano, Kentaro, Tack, Jan, Tan, Victoria Ping Yi, Tang, Xudong, Walker, Marjorie, Wu, Deng‐Chyang, Xiao, Ying‐Lian, Zulkifli, Khairil Khuzaini and Toh, Clarissa (2023). Asia‐Pacific Guidelines for Managing Functional Dyspepsia Overlapping with Other Gastrointestinal Symptoms. Journal of Gastroenterology and Hepatology, 38 (2), 197-209. doi: 10.1111/jgh.16046

Asia‐Pacific Guidelines for Managing Functional Dyspepsia Overlapping with Other Gastrointestinal Symptoms

2023

Journal Article

Placebo effects in functional dyspepsia: causes and implications for clinical trials

Jones, Michael P. and Holtmann, Gerald (2023). Placebo effects in functional dyspepsia: causes and implications for clinical trials. Neurogastroenterology and Motility, 35 (2) e14527, 1-6. doi: 10.1111/nmo.14527

Placebo effects in functional dyspepsia: causes and implications for clinical trials

2023

Journal Article

Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide

Ryder, Robert E.J., Laubner, Katharina, Benes, Marek, Haluzik, Martin, Munro, Lynne, Frydenberg, Harry, Teare, Julian P., Ruban, Aruchana, Fishman, Sigal, Santo, Erwin, Stengel, Rainer, De Jonge, Charlotte, Greve, Jan W., Cohen, Ricardo V., Aboud, Cristina M., Holtmann, Gerald J., Rich, Graeme, McMaster, Jess J., Battelino, Tadej, Kotnik, Primoz, Byrne, James P., Mason, John C., Bessell, Justin, Bascomb, Jeanine, Kow, Lillian, Collins, Janes, Chisholm, Jacob, Pferschy, Peter N., Sourij, Harald ... Seufert, Jochen (2023). Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide. Diabetes Care, 46 (4), e89-e91. doi: 10.2337/dc22-1952

Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide

2023

Journal Article

Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia

Burns, Grace L., Bruce, Jessica K., Minahan, Kyra, Mathe, Andrea, Fairlie, Thomas, Cameron, Raquel, Naudin, Crystal, Nair, Prema M., Potter, Michael D. E., Irani, Mudar Zand, Bollipo, Steven, Foster, Robert, Gan, Lay T., Shah, Ayesha, Koloski, Natasha A., Foster, Paul S., Horvat, Jay C., Veysey, Martin, Holtmann, Gerald, Powell, Nick, Walker, Marjorie M., Talley, Nicholas J. and Keely, Simon (2023). Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia. Frontiers in Immunology, 13 1051632, 1-14. doi: 10.3389/fimmu.2022.1051632

Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia

2022

Journal Article

Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity

Sternes, P. R., Brett, L., Phipps, J., Ciccia, F., Kenna, T., de Guzman, E., Zimmermann, K., Morrison, M., Holtmann, G., Klingberg, E., Mauro, D., McIvor, C., Forsblad-d’Elia, H. and Brown, M. A. (2022). Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity. Arthritis Research and Therapy, 24 (1) 163, 1-10. doi: 10.1186/s13075-022-02853-3

Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity

2022

Journal Article

Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial

Xiao, Mengli, Zhong, Linda L. D., Lam, Wai Ching, Zhao, Yingpan, Gwee, Kok-Ann, Holtmann, Gerald, Tack, Jan, Suzuki, Hidekazu, Chen, Min-Hu, Xiao, Yinglian, Hou, Xiaohua, Liu, Jinsong, Li, Yang, Tang, Xu-Dong and Lu, Fang (2022). Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial. Trials, 23 (1) 454, 1-10. doi: 10.1186/s13063-022-06396-5

Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial

2022

Journal Article

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

Frankel, Adam, Thomson, Iain, Shah, Ayesha, Chen, Chen, Zahir, Syeda Farah, Barbour, Andrew, Holtmann, Gerald and Mark Smithers, B (2022). Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial. BJS Open, 6 (6) zrac132. doi: 10.1093/bjsopen/zrac132

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

2022

Journal Article

Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics

Moy, Naomi, Dulleck, Uwe, Shah, Ayesha, Messmann, Helmut, Thrift, Aaron P., Talley, Nicholas J. and Holtmann, Gerald J. (2022). Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics. Gastrointestinal Endoscopy, 96 (5), 735-742.e3. doi: 10.1016/j.gie.2022.05.023

Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics

2022

Journal Article

The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity

Shah, Ayesha, Kang, Seungha, Talley, Nicholas J., Do, Anh, Walker, Marjorie M., Shanahan, Erin R., Koloski, Natasha A., Jones, Michael P., Keely, Simon, Morrison, Mark and Holtmann, Gerald J. (2022). The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity. Gut Microbes, 14 (1) 2132078, 1-21. doi: 10.1080/19490976.2022.2132078

The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity

2022

Journal Article

How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?

Shah, Ayesha, Pakneeshan, Sahar, Jones, Michael P., Koloski, Natasha, Callaghan, Gavin, Morrison, Mark and Holtmann, Gerald (2022). How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?. Indian Journal of Gastroenterology, 41 (5), 519-524. doi: 10.1007/s12664-022-01286-9

How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?

2022

Journal Article

Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association

Ghoshal, Uday C., Sachdeva, Sanjeev, Ghoshal, Ujjala, Misra, Asha, Puri, Amarender Singh, Pratap, Nitesh, Shah, Ayesha, Rahman, M. Masudur, Gwee, Kok Ann, Tan, Victoria P Y, Ahmed, Tahmeed, Lee, Yeong Yeh, Ramakrishna, B. S., Talukdar, Rupjyoti, Rana, S. V., Sinha, Saroj K, Chen, Minhu, Kim, Nayoung and Holtmann, Gerald (2022). Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association. Indian Journal of Gastroenterology, 41 (5), 483-507. doi: 10.1007/s12664-022-01292-x

Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association

2022

Journal Article

Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies

Koloski, Natasha A., Jones, Michael, Walker, Marjorie M., Horowitz, Michael, Holtmann, Gerald and Talley, Nicholas J. (2022). Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies. Neurogastroenterology and Motility, 35 (1) e14471, 1-11. doi: 10.1111/nmo.14471

Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies

2022

Conference Publication

Diversity of Veillonella in cultures of the duodenal mucosa-associated microbiota suggests species-level differences between people with and without functional gastrointestinal symptoms

Schooth, L., Sid-Ahmed, A., Kang, S., Lim, Y., Fairlie, T., Shah, A., Holtmann, G. and Morrison, M. (2022). Diversity of Veillonella in cultures of the duodenal mucosa-associated microbiota suggests species-level differences between people with and without functional gastrointestinal symptoms. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2022, Sydney, NSW Australia, 9–11 September 2022. Richmond, VIC Australia: John Wiley & Sons.

Diversity of Veillonella in cultures of the duodenal mucosa-associated microbiota suggests species-level differences between people with and without functional gastrointestinal symptoms

2022

Journal Article

Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis

Shah, Ayesha, Thite, Parag, Hansen, Teressa, Kendall, Bradley J., Sanders, David S., Morrison, Mark, Jones, Michael P. and Holtmann, Gerald (2022). Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis. Journal of Gastroenterology and Hepatology, 37 (10), 1844-1852. doi: 10.1111/jgh.15920

Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis

2022

Journal Article

Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS)

Karpe, Avinash V., Liu, Jian-Wei, Shah, Ayesha, Koloski, Natasha, Holtmann, Gerald and Beale, David J. (2022). Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS). Metabolomics, 18 (6) 38, 1-11. doi: 10.1007/s11306-022-01900-z

Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS)

2022

Journal Article

Evidence-based and emerging diet recommendations for small bowel disorders

Rej, Anupam, Potter, Michael D. E., Talley, Nicholas J., Shah, Ayesha, Holtmann, Gerald and Sanders, David Surendran (2022). Evidence-based and emerging diet recommendations for small bowel disorders. American Journal of Gastroenterology, 117 (6), 958-964. doi: 10.14309/ajg.0000000000001764

Evidence-based and emerging diet recommendations for small bowel disorders

2022

Journal Article

Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia

Shah, Ayesha, Talley, Nicholas J. and Holtmann, Gerald (2022). Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia. Frontiers in Neuroscience, 16 830356, 1-12. doi: 10.3389/fnins.2022.830356

Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia

Funding

Current funding

  • 2022 - 2026
    ARC Training Centre for Behavioural Insights for Technology Adoption (BITA) (ARC Industrial Transformation Training Centre Administered by QUT)
    Queensland University of Technology
    Open grant
  • 2021 - 2025
    A practice change for patients with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled intervention to assess efficacy and cost-effectiveness
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2025
    Targeting the gut microbiome as a treatment for Primary Sclerosing Cholangitis: The Queensland Clinical Network Study
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant

Past funding

  • 2020 - 2024
    Modulation of the Gastrointestinal Microbiome with probiotics and subsequent Methane production as a novel approach to treat constipation: A Proof of Principle Study (TRI Sport Grant led by PAH)
    Metro South Hospital and Health Service
    Open grant
  • 2019 - 2024
    Centre for Research Excellence in Digestive Health (NHMRC CRE administered by University of Newcastle)
    University of Newcastle
    Open grant
  • 2016
    Establishing a gnotobiotic germ-free mouse facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    The Australian human microbiota project-microbe isolation facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Pathophysiology of functional dyspepsia: Integration of upper gut function, inflammation and a systems biology approach.
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy (NHMRC Project Grant administered by the University of Newcastle)
    University of Newcastle
    Open grant

Supervision

Availability

Professor Gerald Holtmann is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective.

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Equitability and Accessibility of Faecal Occult Blood Test Based Colorectal Cancer Screening for Disadvantaged Communities.

    Principal Advisor

  • Doctor Philosophy

    Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    IBD and mental health tools: a holistic approach to discovery and appropriate tool.

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.

    Associate Advisor

    Other advisors: Professor Jeff Coombes

  • Doctor Philosophy

    The role of the gut microbiome in alcohol related liver disease

    Associate Advisor

    Other advisors: Professor Jason Connor, Dr Paul Clark

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

Completed supervision

Media

Enquiries

Contact Professor Gerald Holtmann directly for media enquiries about:

  • colon cancer screening
  • Gastroenterology
  • Gut Health
  • Microbiome
  • Neurogastroenterology

Need help?

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