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Professor Gerald Holtmann
Professor

Gerald Holtmann

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Overview

Background

Prof Holtmann is a Clinical Academic in the field of Gastroenterology & Hepatology and Director of Clinical Innovation. He is also Director of the Department of Gastroenterology & Hepatology at the Princess Alexandra Hospital in Queensland and serves on the Board of Directors of the West Moreton Hospital and Health Service and UQ Healthcare. He is a Fellow of Royal Australian Collge of Physicians (RACP, Sydney), the Royal College of Physicians (RCP, London) and Fellow of the Australian Academy of Health and Medical Sciences (AAHMS, Canberra). Besides his Medical Qualifications he also obtained a Master of Business Administration. After completing the clinical training in Medicine and Gastroenterology at the University of Essen in Germany and the Mayo Clinic in Rochester, Minnesota in the United States, he has gained substantial leadership and managerial experience within the health care setting as Director of large Gastroenterology Departments, CEO and General Manager of a University Hospital and Health Care Facilities and has served on the Board of the University Hospital Essen in Germany. His research is in the field of Neurogastroenterology has resulted in peer reviewed publications in key journal including the NEJM, Lancet, Gastroenterology and Gut. More recently his rersearch focus is on the role of the gut microbiome, mucosal and systemic inflammation and brain-gut interactions.

Availability

Professor Gerald Holtmann is:
Available for supervision
Media expert

Works

Search Professor Gerald Holtmann’s works on UQ eSpace

669 works between 1937 and 2026

101 - 120 of 669 works

2024

Journal Article

Double‐blind, randomized, 8‐week multicenter study of the efficacy and safety of STW 5‐IIversus placebo in functional dyspepsia

Vinson, Bettina, Fink, Careen, Wargenau, Manfred, Talley, Nicholas J and Holtmann, Gerald (2024). Double‐blind, randomized, 8‐week multicenter study of the efficacy and safety of STW 5‐IIversus placebo in functional dyspepsia. JGH Open, 8 (5) e13054, 1-9. doi: 10.1002/jgh3.13054

Double‐blind, randomized, 8‐week multicenter study of the efficacy and safety of STW 5‐IIversus placebo in functional dyspepsia

2024

Conference Publication

A Multifaceted Ecological Approach To Explore Links Between Environmental Factors And The Epidemiology Of Disorders Of Gut-brain Interaction

Fairlie, Thomas, Shah, Ayesha, Koloski, Natasha A., Moy, Naomi, Wong, Reuben K., Fang, Xiucai, Ghoshal, Uday C., Kashyap, Purna, Mulak, Agata, Lee, Yeong Yeh, Sperber, Ami D., Jones, Michael P. and Holtmann, Gerald J. (2024). A Multifaceted Ecological Approach To Explore Links Between Environmental Factors And The Epidemiology Of Disorders Of Gut-brain Interaction. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)03274-8

A Multifaceted Ecological Approach To Explore Links Between Environmental Factors And The Epidemiology Of Disorders Of Gut-brain Interaction

2024

Conference Publication

Exercise Training Improves Gastrointestinal Symptoms In People With A Disorder Of The Gut Brain Interaction (DGBI): Systemic Review And Meta-analysis

Bell, Katherine, Ferstera, Naomi, Durney, Jacinta, Nicol, Jennifer, Holtmann, Gerald and Coombes, Jeff (2024). Exercise Training Improves Gastrointestinal Symptoms In People With A Disorder Of The Gut Brain Interaction (DGBI): Systemic Review And Meta-analysis. Research to Practice 2024, Sydney, NSW Australia, 2-4 May 2024. Clinical Exercise Physiology Association. doi: 10.31189/2165-7629-13-s2.491

Exercise Training Improves Gastrointestinal Symptoms In People With A Disorder Of The Gut Brain Interaction (DGBI): Systemic Review And Meta-analysis

2024

Conference Publication

TOFACITINIB DEMONSTRATES PRELIMINARY EFFICACY IN INDUCTION OF REMISSION IN CHRONIC POUCHITIS

Khoo, Emi, Amiss, Anna, Ding, Nik S., Bryant, Robert V., Mohsen, Waled, Connor, Susan J., Leong, Rupert, Croft, Anthony, Lynch, Kate D., Sparrow, Miles, De Cruz, Peter, An, Yoon-Kyo, Holtmann, Gerald J. and Begun, Jakob (2024). TOFACITINIB DEMONSTRATES PRELIMINARY EFFICACY IN INDUCTION OF REMISSION IN CHRONIC POUCHITIS. Digestive Disease Week (DDW), Washington Dc, May 18-21, 2024. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.

TOFACITINIB DEMONSTRATES PRELIMINARY EFFICACY IN INDUCTION OF REMISSION IN CHRONIC POUCHITIS

2024

Conference Publication

A Minority With Childhood Disorders Of Gut-brain Interactions Continue In Adulthood, But Mood Disorders Increase The Odds Of Childhood Gastrointestinal Symptoms Persisting Into Adulthood

Jones, Michael P., Koloski, Natasha A., Walker, Marjorie M., Holtmann, Gerald J., Shah, Ayesha, Eslick, Guy D. and Talley, Nicholas J. (2024). A Minority With Childhood Disorders Of Gut-brain Interactions Continue In Adulthood, But Mood Disorders Increase The Odds Of Childhood Gastrointestinal Symptoms Persisting Into Adulthood. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)01049-7

A Minority With Childhood Disorders Of Gut-brain Interactions Continue In Adulthood, But Mood Disorders Increase The Odds Of Childhood Gastrointestinal Symptoms Persisting Into Adulthood

2024

Conference Publication

A Novel Isolate Of Streptococcus Salivarius, AGIRA0003, Disrupts Tight Junctions Ex Vivo In Functional Dyspepsia

Burns, Grace L., Wark, Jasmine A., Hoedt, Emily C., Minahan, Kyra, Sherwin, Simonne, Bruce, Jessica K., Lim, Yenkai, Teh, Jing Jie, Jamaluddin, M. Fairuz, Soh, Wai Sinn, Caban, Shandelle, Almazi, Juhura, Woldu, Ameha S., Dun, Matthew D., Potter, Michael D., Shanahan, Erin R., Holtmann, Gerald J., Walker, Marjorie M., Morrison, Mark, Talley, Nicholas J. and Keely, Simon (2024). A Novel Isolate Of Streptococcus Salivarius, AGIRA0003, Disrupts Tight Junctions Ex Vivo In Functional Dyspepsia. Digestive Disease Week (DDW) 2024, Chicago, IL United States, 18-21 May 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(24)02260-1

A Novel Isolate Of Streptococcus Salivarius, AGIRA0003, Disrupts Tight Junctions Ex Vivo In Functional Dyspepsia

2024

Journal Article

A Minority of Childhood Disorders of Gut-Brain Interaction Persist Into Adulthood: A Risk-Factor Analysis

Jones, Michael P., Koloski, Natasha A., Walker, Marjorie M., Holtmann, Gerald J., Shah, Ayesha, Eslick, Guy D. and Talley, Nicholas J. (2024). A Minority of Childhood Disorders of Gut-Brain Interaction Persist Into Adulthood: A Risk-Factor Analysis. American Journal of Gastroenterology, 119 (9), 1894-1900. doi: 10.14309/ajg.0000000000002751

A Minority of Childhood Disorders of Gut-Brain Interaction Persist Into Adulthood: A Risk-Factor Analysis

2024

Journal Article

What impact has the Centre of Research Excellence in Digestive Health made in the field of gastrointestinal health in Australia and internationally? Study protocol for impact evaluation using the FAIT framework

Koloski, Natasha, Duncanson, Kerith, Ramanathan, Shanthi Ann, Rao, Melanie, Holtmann, Gerald and Talley, Nicholas J (2024). What impact has the Centre of Research Excellence in Digestive Health made in the field of gastrointestinal health in Australia and internationally? Study protocol for impact evaluation using the FAIT framework. BMJ Open, 14 (3) e076839, 1-8. doi: 10.1136/bmjopen-2023-076839

What impact has the Centre of Research Excellence in Digestive Health made in the field of gastrointestinal health in Australia and internationally? Study protocol for impact evaluation using the FAIT framework

2024

Journal Article

Healthcare utilization patterns: irritable bowel syndrome, inflammatory bowel disease, and gastroesophageal reflux disease

Koloski, Natasha, Shah, Ayesha, Kaan, Iain, Ben Jacob, Ronen, Talley, Nicholas J., Jones, Michael P. and Holtmann, Gerald (2024). Healthcare utilization patterns: irritable bowel syndrome, inflammatory bowel disease, and gastroesophageal reflux disease. Digestive Diseases and Sciences, 69 (5), 1626-1635. doi: 10.1007/s10620-024-08297-w

Healthcare utilization patterns: irritable bowel syndrome, inflammatory bowel disease, and gastroesophageal reflux disease

2024

Journal Article

Cost-effectiveness of taurolidine-citrate in a cohort of patients with intestinal failure receiving home parenteral nutrition

Williams, Thomas J., Moy, Naomi, Kaazan, Patricia, Callaghan, Gavin, Holtmann, Gerald and Martin, Neal (2024). Cost-effectiveness of taurolidine-citrate in a cohort of patients with intestinal failure receiving home parenteral nutrition. Journal of Parenteral and Enteral Nutrition, 48 (2), 165-173. doi: 10.1002/jpen.2589

Cost-effectiveness of taurolidine-citrate in a cohort of patients with intestinal failure receiving home parenteral nutrition

2024

Journal Article

Efficacy and Safety of STW 5-II for Functional Dyspepsia Treatment: A Patient Data-Based Meta-Analysis

Andresen, Viola, Shah, Ayesha, Fink, Careen, Rabini, Sabine, Wargenau, Manfred and Holtmann, Gerald (2024). Efficacy and Safety of STW 5-II for Functional Dyspepsia Treatment: A Patient Data-Based Meta-Analysis. Digestion, 105 (3), 166-174. doi: 10.1159/000535672

Efficacy and Safety of STW 5-II for Functional Dyspepsia Treatment: A Patient Data-Based Meta-Analysis

2024

Journal Article

Erratum: autism-related dietary preferences mediate autism-gut microbiome associations

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2024). Erratum: autism-related dietary preferences mediate autism-gut microbiome associations. Cell, 187 (2), 495-510. doi: 10.1016/j.cell.2023.12.001

Erratum: autism-related dietary preferences mediate autism-gut microbiome associations

2024

Book Chapter

Rolle des gastrointestinalen Mikrobioms bei Erkrankungen der Darm-Hirn-Achse

Holtmann, Gerald, Shah, Ayesha and Morrison, Mark (2024). Rolle des gastrointestinalen Mikrobioms bei Erkrankungen der Darm-Hirn-Achse. Gastrointestinales Mikrobiom. (pp. 105-116) Heidelberg, Germany: Springer. doi: 10.1007/978-3-662-68455-9_9

Rolle des gastrointestinalen Mikrobioms bei Erkrankungen der Darm-Hirn-Achse

2024

Journal Article

Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis

Shah, Ayesha, Jones, Michael P., Callaghan, Gavin, Fairlie, Thomas, Ma, Xiaomin, Culver, Emma L., Stuart, Katherine, De Cruz, Peter, O’Beirne, James, Tabibian, James H., Dignass, Axel, Canbay, Ali, Gores, Gregory J. and Holtmann, Gerald J. (2024). Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis. Hepatology Communications, 8 (1) e0347. doi: 10.1097/hc9.0000000000000347

Efficacy and safety of biologics in primary sclerosing cholangitis with inflammatory bowel disease: A systematic review and meta-analysis

2024

Conference Publication

Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis

Khoo, E., Amiss, A., Ding, J. N., Bryant, R., Mohsen, W., Connor, S., Leung, R., Croft, A., Lynch, K., Sparrow, M., De Cruz, P., An, Y. K., Holtmann, G. and Begun, J. (2024). Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis. 19th Congress of ECCO, Stockholm, Sweden, 21-24 February 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjad212.0984

Tofacitinib demonstrates preliminary efficacy in induction of remission in chronic pouchitis

2023

Journal Article

TRAV26-2 T cell receptor expression is associated with mucosal lymphocyte response to wheat proteins in functional dyspepsia patients

Burns, Grace L., Potter, Michael, Mathe, Andrea, Bruce, Jessica, Minahan, Kyra, Barnes, Jessica L., Pryor, Jennifer, Nieva, Cheenie, Sherwin, Simonne, Cuskelly, Annalisa, Fairlie, Thomas, Cameron, Raquel, Bollipo, Steven, Irani, Mudar Zand, Foster, Robert, Gan, Lay T., Shah, Ayesha, Koloski, Natasha, Foster, Paul S., Horvat, Jay C., Walker, Marjorie M., Powell, Nick, Veysey, Martin, Duncanson, Kerith, Holtmann, Gerald, Talley, Nicholas J. and Keely, Simon (2023). TRAV26-2 T cell receptor expression is associated with mucosal lymphocyte response to wheat proteins in functional dyspepsia patients. Clinical and Translational Gastroenterology, 14 (12) e00638, e00638. doi: 10.14309/ctg.0000000000000638

TRAV26-2 T cell receptor expression is associated with mucosal lymphocyte response to wheat proteins in functional dyspepsia patients

2023

Conference Publication

Small intestinal bacterial overgrowth in chronic liver disease: a systematic review and meta-analysis of case-control studies

Spannenburg, L., Shah, A., Thite, P., Fairlie, T., Moniruzzaman, M., Stuart, K. A., Koloski, N. A., Morrison, M., Jones, M. P. and Holtmann, G. J. (2023). Small intestinal bacterial overgrowth in chronic liver disease: a systematic review and meta-analysis of case-control studies. 31st United European Gastroenterology Week 2023, Copenhagen, Denmark, 14-17 October 2023. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/ueg2.1246

Small intestinal bacterial overgrowth in chronic liver disease: a systematic review and meta-analysis of case-control studies

2023

Conference Publication

Small intestinal bacterial overgrowth in patients with intestinal failure: A systematic review and meta-analysis

Ma, X., Shah, A., Fairlie, T., Martin, N., Jones, M., Koloski, N., Morrison, M. and Holtmann, G. (2023). Small intestinal bacterial overgrowth in patients with intestinal failure: A systematic review and meta-analysis. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2023, Brisbane, QLD Australia, 2-5 September 2023. Richmond, VIC Australia: John Wiley & Sons.

Small intestinal bacterial overgrowth in patients with intestinal failure: A systematic review and meta-analysis

2023

Conference Publication

Small intestinal bacterial overgrowth in chronic liver disease: A systematic review and meta-analysis of case-control studies

Spannenburg, L., Shah, A., Thite, P., Fairlie, T., Koloski, N., Moniruzzaman, M., Morrison, M., Jones, M. and Holtmann, G. (2023). Small intestinal bacterial overgrowth in chronic liver disease: A systematic review and meta-analysis of case-control studies. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2023, Brisbane, QLD Australia, 2-5 September 2023. Richmond, VIC Australia: John Wiley & Sons.

Small intestinal bacterial overgrowth in chronic liver disease: A systematic review and meta-analysis of case-control studies

2023

Conference Publication

Alcohol dependence and alcohol-related liver disease after bariatric surgery

Williams, T., Palmer, A., Connor, J., Holtmann, G. and Clark, P. (2023). Alcohol dependence and alcohol-related liver disease after bariatric surgery. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2023, Brisbane, QLD, Australia, 2—5 September 2023. Richmond, VIC Australia: John Wiley & Sons.

Alcohol dependence and alcohol-related liver disease after bariatric surgery

Funding

Past funding

  • 2022 - 2026
    ARC Training Centre for Behavioural Insights for Technology Adoption (BITA) (ARC Industrial Transformation Training Centre Administered by QUT)
    Queensland University of Technology
    Open grant
  • 2021 - 2025
    A practice change for patients with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled intervention to assess efficacy and cost-effectiveness
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2024
    Modulation of the Gastrointestinal Microbiome with probiotics and subsequent Methane production as a novel approach to treat constipation: A Proof of Principle Study (TRI Sport Grant led by PAH)
    Metro South Hospital and Health Service
    Open grant
  • 2020 - 2025
    Targeting the gut microbiome as a treatment for Primary Sclerosing Cholangitis: The Queensland Clinical Network Study
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2019 - 2024
    Centre for Research Excellence in Digestive Health (NHMRC CRE administered by University of Newcastle)
    University of Newcastle
    Open grant
  • 2016
    Establishing a gnotobiotic germ-free mouse facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    The Australian human microbiota project-microbe isolation facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Pathophysiology of functional dyspepsia: Integration of upper gut function, inflammation and a systems biology approach.
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy (NHMRC Project Grant administered by the University of Newcastle)
    University of Newcastle
    Open grant

Supervision

Availability

Professor Gerald Holtmann is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    IBD and mental health tools: a holistic approach to discovery and appropriate tool.

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Gastrointestinal symptoms and Disorders of Gut-Brain Interaction: clinical manifestations and treatment response

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Targeting the gastrointestinal mucosa associated microbiome to improve clinical outcomes

    Associate Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

  • Doctor Philosophy

    The role of the gut microbiome in alcohol related liver disease

    Associate Advisor

    Other advisors: Professor Jason Connor, Honorary Professor Paul Clark

Completed supervision

Media

Enquiries

Contact Professor Gerald Holtmann directly for media enquiries about:

  • colon cancer screening
  • Gastroenterology
  • Gut Health
  • Microbiome
  • Neurogastroenterology

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au