Professor Gerald Holtmann
Professor

Gerald Holtmann

Email: 
Phone: 
+61 7 3176 7792

Background

Prof Holtmann is a Clinical Academic in the field of Gastroenterology & Hepatology and Director of Clinical Innovation. He is also Director of the Department of Gastroenterology & Hepatology at the Princess Alexandra Hospital in Queensland and serves on the Board of Directors of the West Moreton Hospital and Health Service and UQ Healthcare. He is a Fellow of Royal Australian Collge of Physicians (RACP, Sydney), the Royal College of Physicians (RCP, London) and Fellow of the Australian Academy of Health and Medical Sciences (AAHMS, Canberra). Besides his Medical Qualifications he also obtained a Master of Business Administration. After completing the clinical training in Medicine and Gastroenterology at the University of Essen in Germany and the Mayo Clinic in Rochester, Minnesota in the United States, he has gained substantial leadership and managerial experience within the health care setting as Director of large Gastroenterology Departments, CEO and General Manager of a University Hospital and Health Care Facilities and has served on the Board of the University Hospital Essen in Germany. His research is in the field of Neurogastroenterology has resulted in peer reviewed publications in key journal including the NEJM, Lancet, Gastroenterology and Gut. More recently his rersearch focus is on the role of the gut microbiome, mucosal and systemic inflammation and brain-gut interactions.

Availability

Professor Gerald Holtmann is:
Available for supervision
Media expert

Search Professor Gerald Holtmann’s works on UQ eSpace

539 works between 1986 and 2025
All (539) Journal Article (403) Book Chapter (4) Conference Publication (132)

121 - 140 of 539 works

2022

Journal Article

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials

Rubin, David T, Dotan, Iris, DuVall, Aaron, Bouhnik, Yoram, Radford-Smith, Graham, Higgins, Peter D R, Mishkin, Daniel S, Arrisi, Pablo, Scalori, Astrid, Oh, Young S, Tole, Swati, Chai, Akiko, Chamberlain-James, Kirsten, Lacey, Stuart, McBride, Jacqueline, Panés, Julian, Abdulkhakov, Rustem, Abu Bakar, Norasiah, Aguilar, Humberto, Aizenberg, Diego, Akpinar, Hale, Akriviadis, Evangelos, Alexeeva, Olga, Alikhanov, Bagdadi, Alvarisqueta, Andres, Ananthakrishnan, Ashwin, Andrews, Jane, Arlukowicz, Tomasz, Atkinson, Nathan ... on behalf of the HIBISCUS Study Group (2022). Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials. The Lancet Gastroenterology and Hepatology, 7 (1), 17-27. doi: 10.1016/S2468-1253(21)00338-1

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials

2021

Journal Article

The role of mood state and emotion regulation in the discrepancy between gastrointestinal symptom burden recorded prospectively and via recall questionnaire

Jones, Michael P., Yun, Grace, Wass, Fiona, Rixon, Hayley, Shah, Ayesha, Walker, Marjorie M., Koloski, Natasha A., Holtmann, Gerald, Talley, Nicholas J. and Beath, Alissa P. (2021). The role of mood state and emotion regulation in the discrepancy between gastrointestinal symptom burden recorded prospectively and via recall questionnaire. Neurogastroenterology and Motility, 34 (7) e14304, 1-8. doi: 10.1111/nmo.14304

The role of mood state and emotion regulation in the discrepancy between gastrointestinal symptom burden recorded prospectively and via recall questionnaire

2021

Journal Article

Clusters of community-dwelling individuals empirically derived from stool diaries correspond with clinically meaningful outcomes

Jones, Michael P., Walter, Susanna, Talley, Nicholas J., Walker, Marjorie M., Holtmann, Gerald J., Shah, Ayesha, D'Amato, Mauro, Agréus, Lars and Andreasson, Anna (2021). Clusters of community-dwelling individuals empirically derived from stool diaries correspond with clinically meaningful outcomes. European Journal of Gastroenterology and Hepatology, 33 (S1), e740-e745. doi: 10.1097/MEG.0000000000002236

Clusters of community-dwelling individuals empirically derived from stool diaries correspond with clinically meaningful outcomes

2021

Journal Article

S3 guideline update on irritable bowel syndrome: Definition, pathophysiology, diagnosis and treatment. Joint guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021/016 Update S3-leitlinie reizdarmsyndrom: Definition, pathophysiologie, diagnostik und therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für neurogastroenterologie und Motilität (DGNM) Juni 2021 - AWMF-registriernummer: 021/016

Layer, Peter, Andresen, Viola, Allescher, H., Bischoff, S. C., Claßen, M., Elsenbruch, S., Freitag, M., Frieling, T., Gebhard, M., Goebel-Stengel, M., Häuser, W., Holtmann, G., Keller, J., Kreis, M. E., Kruis, W., Langhorst, J., Jansen, P. Lynen, Madisch, A., Mönnikes, H., Müller-Lissner, S., Niesler, B., Pehl, C., Pohl, D., Raithel, M., Röhrig-Herzog, G., Schemann, M., Schmiedel, S., Schwille-Kiuntke, J., Storr, M. ... Wedel, T. (2021). S3 guideline update on irritable bowel syndrome: Definition, pathophysiology, diagnosis and treatment. Joint guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021/016 Update S3-leitlinie reizdarmsyndrom: Definition, pathophysiologie, diagnostik und therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für neurogastroenterologie und Motilität (DGNM) Juni 2021 - AWMF-registriernummer: 021/016. Zeitschrift fur Gastroenterologie, 59 (12), 1323-1415. doi: 10.1055/a-1591-4794

S3 guideline update on irritable bowel syndrome: Definition, pathophysiology, diagnosis and treatment. Joint guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021/016 Update S3-leitlinie reizdarmsyndrom: Definition, pathophysiologie, diagnostik und therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für neurogastroenterologie und Motilität (DGNM) Juni 2021 - AWMF-registriernummer: 021/016

2021

Journal Article

Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study

Ejova, Anastasia, Badcock, Nicholas A., McKerchar, Sarah, Beath, Alissa P., Swift, Claire, Talley, Nicholas J., Holtmann, Gerald, Walker, Marjorie M. and Jones, Michael P. (2021). Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study. International Journal of Psychophysiology, 170, 30-42. doi: 10.1016/j.ijpsycho.2021.09.006

Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study

2021

Journal Article

Autism-related dietary preferences mediate autism-gut microbiome associations

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2021). Autism-related dietary preferences mediate autism-gut microbiome associations. Cell, 184 (24), 5916-5931.e17. doi: 10.1016/j.cell.2021.10.015

Autism-related dietary preferences mediate autism-gut microbiome associations

2021

Journal Article

Antibiotic use but not gastrointestinal infection frequently precedes first diagnosis of functional gastrointestinal disorders

Jones, Michael P., Shah, Ayesha, Walker, Marjorie M., Koloski, Natasha A., Holtmann, Gerald and Talley, Nicholas J. (2021). Antibiotic use but not gastrointestinal infection frequently precedes first diagnosis of functional gastrointestinal disorders. United European Gastroenterology Journal, 9 (9), 1074-1080. doi: 10.1002/ueg2.12164

Antibiotic use but not gastrointestinal infection frequently precedes first diagnosis of functional gastrointestinal disorders

2021

Journal Article

Physician perceptions on the use of antibiotics and probiotics in adults: an international survey in the Asia-Pacific area

Ghoshal, Uday C., Gwee, Kok-Ann, Holtmann, Gerald, Li, Yanmei, Park, Soo Jung, Simadibrata, Marcellus, Sugano, Kentaro, Cohen, Henry and Quigley, Eamonn M. M. (2021). Physician perceptions on the use of antibiotics and probiotics in adults: an international survey in the Asia-Pacific area. Frontiers in Cellular and Infection Microbiology, 11 722700, 722700. doi: 10.3389/fcimb.2021.722700

Physician perceptions on the use of antibiotics and probiotics in adults: an international survey in the Asia-Pacific area

2021

Journal Article

Draft genome sequence of streptococcus salivarius AGIRA0003, isolated from functional gastrointestinal disorder duodenal tissue

Hoedt, Emily C., Shanahan, Erin R., Keely, Simon, Shah, Ayesha, Burns, Grace L., Holtmann, Gerald J., Talley, Nicholas J. and Morrison, Mark (2021). Draft genome sequence of streptococcus salivarius AGIRA0003, isolated from functional gastrointestinal disorder duodenal tissue. Microbiology Resource Announcements, 10 (39) e00758, e0075821. doi: 10.1128/MRA.00758-21

Draft genome sequence of streptococcus salivarius AGIRA0003, isolated from functional gastrointestinal disorder duodenal tissue

2021

Journal Article

Sleep disturbances in the irritable bowel syndrome and functional dyspepsia are independent of psychological distress: a population-based study of 1322 Australians

Koloski, Natasha A., Jones, Michael, Walker, Marjorie M., Keely, Simon, Holtmann, Gerald and Talley, Nicholas J. (2021). Sleep disturbances in the irritable bowel syndrome and functional dyspepsia are independent of psychological distress: a population-based study of 1322 Australians. Alimentary Pharmacology and Therapeutics, 54 (5) apt.16500, 627-636. doi: 10.1111/apt.16500

Sleep disturbances in the irritable bowel syndrome and functional dyspepsia are independent of psychological distress: a population-based study of 1322 Australians

2021

Conference Publication

Differentiation and capture of the human duodenal mucosa-associated microbiota by a novel ex vivo combination of microbe culture and metagenomic sequencing

Schooth, L., Kang, S., Lim, Y., Shah, A., Fairlie, T., Jimenez-Loayza, J., Teh, J.-J., Holtmann, G. and Morrison, M. (2021). Differentiation and capture of the human duodenal mucosa-associated microbiota by a novel ex vivo combination of microbe culture and metagenomic sequencing. GESA AGW 2021, Online, 4-12 September 2021. Richmond, VIC Australia: Wiley-Blackwell.

Differentiation and capture of the human duodenal mucosa-associated microbiota by a novel ex vivo combination of microbe culture and metagenomic sequencing

2021

Journal Article

Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis

Johnson, Kevin M., Fischer, Ryan T., Holtmann, Gerald J., Shah, Ayesha, Alrabadi, Leina and Lewindon, Peter (2021). Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis. Hepatology, 74 (3), 1716-1717. doi: 10.1002/hep.31764

Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis

2021

Journal Article

Concomitant irritable bowel syndrome does not influence the response to antimicrobial therapy in patients with functional dyspepsia

Shah, Ayesha, Gurusamy, Saravana Ruban, Hansen, Teressa, Callaghan, Gavin, Talley, Nicholas J., Koloski, Natasha, Walker, Marjorie M., Jones, Michael P., Morrison, Mark and Holtmann, Gerald J. (2021). Concomitant irritable bowel syndrome does not influence the response to antimicrobial therapy in patients with functional dyspepsia. Digestive Diseases and Sciences, 67 (6), 2299-2309. doi: 10.1007/s10620-021-07149-1

Concomitant irritable bowel syndrome does not influence the response to antimicrobial therapy in patients with functional dyspepsia

2021

Journal Article

Routine assessment of gastrointestinal symptom using a validated questionnaire in the clinical setting to assess the probability of organic or functional gastrointestinal diseases

Jones, Michael P., Shah, Ayesha, Ben-Jacob, Ronen, Talley, Nicholas J., Hansen, Teressa, Walker, Marjorie M., Gray, Marcus, Koloski, Natasha A. and Holtmann, Gerald (2021). Routine assessment of gastrointestinal symptom using a validated questionnaire in the clinical setting to assess the probability of organic or functional gastrointestinal diseases. Neurogastroenterology and Motility, 33 (8) e14091, e14091. doi: 10.1111/nmo.14091

Routine assessment of gastrointestinal symptom using a validated questionnaire in the clinical setting to assess the probability of organic or functional gastrointestinal diseases

2021

Conference Publication

Development and validation of the comprehensive endoscopy satisfaction tool (CEST)

McMaster, Jessica J., Kutyla, Marguerite J., Haig, Adam, Koloski, Natasha, Hourigan, Luke F., Meeusen, Vera, Shah, Ayesha, Talley, Nicholas J., Jones, Michael P. and Holtmann, Gerald J. (2021). Development and validation of the comprehensive endoscopy satisfaction tool (CEST). Asia Pacific Digestive Week (APDW), Kuala Lumpur, Malaysia, 19–22 August 2021. Richmond, VIC Australia: John Wiley & Sons. doi: 10.1111/jgh.15607

Development and validation of the comprehensive endoscopy satisfaction tool (CEST)

2021

Journal Article

Letter: budesonide for functional dyspepsia with duodenal eosinophilia—randomised, double-blind, placebo-controlled parallel-group trial

Talley, N. J., Walker, M. M., Jones, M., Keely, S., Koloski, N., Cameron, R., Fairlie, T., Burns, G., Shah, A., Hansen, T., Harris, G. and Holtmann, G. (2021). Letter: budesonide for functional dyspepsia with duodenal eosinophilia—randomised, double-blind, placebo-controlled parallel-group trial. Alimentary Pharmacology and Therapeutics, 53 (12), 1332-1333. doi: 10.1111/apt.16396

Letter: budesonide for functional dyspepsia with duodenal eosinophilia—randomised, double-blind, placebo-controlled parallel-group trial

2021

Journal Article

Patient positioning guidelines for gastrointestinal endoscopic procedures

Meeusen, Vera, Kim, Nick, Elson, Jerome, Ma, Regan, Newman, Fiona, Bendeich, Jess and Holtmann, Gerald (2021). Patient positioning guidelines for gastrointestinal endoscopic procedures. Gastroenterology Nursing, 44 (3), 185-191. doi: 10.1097/SGA.0000000000000534

Patient positioning guidelines for gastrointestinal endoscopic procedures

2021

Journal Article

Small intestinal bacterial overgrowth in functional dyspepsia: a systematic review and meta-analysis

Gurusamy, Saravana Ruban, Shah, Ayesha, Talley, Nicholas J., Koloski, Natasha, Jones, Michael P., Walker, Marjorie M., Morrison, Mark and Holtmann, Gerald (2021). Small intestinal bacterial overgrowth in functional dyspepsia: a systematic review and meta-analysis. The American Journal of Gastroenterology, 116 (5), 935-942. doi: 10.14309/ajg.0000000000001197

Small intestinal bacterial overgrowth in functional dyspepsia: a systematic review and meta-analysis

2021

Journal Article

Epigastric symptom response to low FODMAP dietary advice compared with standard dietetic advice in individuals with functional dyspepsia

Staudacher, Heidi M., Nevin, Amy N., Duff, Christopher, Kendall, Bradley J. and Holtmann, Gerald J. (2021). Epigastric symptom response to low FODMAP dietary advice compared with standard dietetic advice in individuals with functional dyspepsia. Neurogastroenterology and Motility, 33 (11) e14148, e14148. doi: 10.1111/nmo.14148

Epigastric symptom response to low FODMAP dietary advice compared with standard dietetic advice in individuals with functional dyspepsia

2021

Journal Article

From trash to gold: Gastrointestinal microbiome research in patients with functional gastrointestinal disorders

Holtmann, Gerald, Shah, Ayesha and Morrison, Mark (2021). From trash to gold: Gastrointestinal microbiome research in patients with functional gastrointestinal disorders. Journal of Investigative Medicine, 69 (4), 793-795. doi: 10.1136/jim-2021-001903

From trash to gold: Gastrointestinal microbiome research in patients with functional gastrointestinal disorders

Current funding

  • 2022 - 2026
    ARC Training Centre for Behavioural Insights for Technology Adoption (BITA) (ARC Industrial Transformation Training Centre Administered by QUT)
    Queensland University of Technology
    Open grant
  • 2021 - 2025
    A practice change for patients with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled intervention to assess efficacy and cost-effectiveness
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2024
    Modulation of the Gastrointestinal Microbiome with probiotics and subsequent Methane production as a novel approach to treat constipation: A Proof of Principle Study (TRI Sport Grant led by PAH)
    Metro South Hospital and Health Service
    Open grant
  • 2020 - 2025
    Targeting the gut microbiome as a treatment for Primary Sclerosing Cholangitis: The Queensland Clinical Network Study
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2019 - 2024
    Centre for Research Excellence in Digestive Health (NHMRC CRE administered by University of Newcastle)
    University of Newcastle
    Open grant
  • 2016
    Establishing a gnotobiotic germ-free mouse facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    The Australian human microbiota project-microbe isolation facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Pathophysiology of functional dyspepsia: Integration of upper gut function, inflammation and a systems biology approach.
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy (NHMRC Project Grant administered by the University of Newcastle)
    University of Newcastle
    Open grant

Availability

Professor Gerald Holtmann is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    IBD and mental health tools: a holistic approach to discovery and appropriate tool.

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective.

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    The role of the gut microbiome in alcohol related liver disease

    Associate Advisor

    Other advisors: Professor Jason Connor, Dr Paul Clark

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

  • Doctor Philosophy

    Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.

    Associate Advisor

    Other advisors: Professor Jeff Coombes

Completed supervision

Enquiries

Contact Professor Gerald Holtmann directly for media enquiries about:

  • colon cancer screening
  • Gastroenterology
  • Gut Health
  • Microbiome
  • Neurogastroenterology

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