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Professor Gerald Holtmann
Professor

Gerald Holtmann

Email: 
Phone: 
+61 7 3176 7792

Overview

Background

Prof Holtmann is a Clinical Academic in the field of Gastroenterology & Hepatology and Director of Clinical Innovation. He is also Director of the Department of Gastroenterology & Hepatology at the Princess Alexandra Hospital in Queensland and serves on the Board of Directors of the West Moreton Hospital and Health Service and UQ Healthcare. He is a Fellow of Royal Australian Collge of Physicians (RACP, Sydney), the Royal College of Physicians (RCP, London) and Fellow of the Australian Academy of Health and Medical Sciences (AAHMS, Canberra). Besides his Medical Qualifications he also obtained a Master of Business Administration. After completing the clinical training in Medicine and Gastroenterology at the University of Essen in Germany and the Mayo Clinic in Rochester, Minnesota in the United States, he has gained substantial leadership and managerial experience within the health care setting as Director of large Gastroenterology Departments, CEO and General Manager of a University Hospital and Health Care Facilities and has served on the Board of the University Hospital Essen in Germany. His research is in the field of Neurogastroenterology has resulted in peer reviewed publications in key journal including the NEJM, Lancet, Gastroenterology and Gut. More recently his rersearch focus is on the role of the gut microbiome, mucosal and systemic inflammation and brain-gut interactions.

Availability

Professor Gerald Holtmann is:
Available for supervision
Media expert

Works

Search Professor Gerald Holtmann’s works on UQ eSpace

531 works between 1986 and 2025

181 - 200 of 531 works

2019

Journal Article

Effects of antibiotic therapy in primary sclerosing cholangitis with and without inflammatory bowel disease: a systematic review and meta-analysis

Shah, Ayesha, Crawford, Darrel, Burger, Daniel, Martin, Neal, Walker, Marjorie, Talley, Nicholas J., Tallis, Caroline, Jones, Michael, Stuart, Katherine, Keely, Simon, Lewindon, Peter, MacDonald, Graeme A., Morrison, Mark and Holtmann, Gerald J. (2019). Effects of antibiotic therapy in primary sclerosing cholangitis with and without inflammatory bowel disease: a systematic review and meta-analysis. Seminars in Liver Disease, 39 (4), 432-441. doi: 10.1055/s-0039-1688501

Effects of antibiotic therapy in primary sclerosing cholangitis with and without inflammatory bowel disease: a systematic review and meta-analysis

2019

Conference Publication

Factorial analysis-based assessment of the Mucosa Associated Microbiome

Holtmann, Gerald, Morrison, Mark, Talley, Nicholas, Koloski, Natasha, Shah, Ayesha and Jones, Michael (2019). Factorial analysis-based assessment of the Mucosa Associated Microbiome. Asia Pacific Digestive Week, Kolkata, India, 12–15 December 2019. Hoboken, NJ United States: Wiley.

Factorial analysis-based assessment of the Mucosa Associated Microbiome

2019

Conference Publication

Tu1618 – Patients with Functional Gastrointestinal Disorders (FGIDS) Benefit from a Multidisciplinary Integrated Treatment Approach to Reduce Anxiety and Depressive Symptoms

Bray, Nicola, Koloski, Natasha A., Jones, Michael P., Do, Anh, Talley, Nicholas J., Billin, Abi, Bettens, Gemma, McAllister, Sarah, Pang, Siong, Arthur, Leela, Campos, Jane, Chao, Che-Yung, Catague, Rachel, Whaley, Amanda, Macdonald, Graeme A. and Holtmann, Gerald (2019). Tu1618 – Patients with Functional Gastrointestinal Disorders (FGIDS) Benefit from a Multidisciplinary Integrated Treatment Approach to Reduce Anxiety and Depressive Symptoms. Digestive Disease Week, San Diego, CA, United States, 18-21 May, 2019. PHILADELPHIA: Elsevier BV. doi: 10.1016/s0016-5085(19)39623-4

Tu1618 – Patients with Functional Gastrointestinal Disorders (FGIDS) Benefit from a Multidisciplinary Integrated Treatment Approach to Reduce Anxiety and Depressive Symptoms

2019

Book Chapter

Clinical conditions associated with bacterial overgrowth

Shah, Ayesha and Holtmann, Gerald (2019). Clinical conditions associated with bacterial overgrowth. Gastrointestinal diseases and their associated infections. (pp. 67-83) edited by Guy D. Eslick. St. Louis, MO, United States: Elsevier. doi: 10.1016/B978-0-323-54843-4.00006-4

Clinical conditions associated with bacterial overgrowth

2019

Journal Article

Immune activation in functional gastrointestinal disorders

Burns, Grace, Pryor, Jennifer, Holtmann, Gerald, Walker, Marjorie M., Talley, Nicholas J. and Keely, Simon (2019). Immune activation in functional gastrointestinal disorders. Gastroenterology and Hepatology, 15 (10), 539-548.

Immune activation in functional gastrointestinal disorders

2018

Journal Article

Gastroduodenal "Dysbiosis": a new clinical entity

Shah, Ayesha, Morrison, Mark and Holtmann, Gerald J. (2018). Gastroduodenal "Dysbiosis": a new clinical entity. Current Treatment Options in Gastroenterology, 16 (4), 591-604. doi: 10.1007/s11938-018-0207-x

Gastroduodenal "Dysbiosis": a new clinical entity

2018

Conference Publication

Systematic review and meta-analysis: Prevalence of small intestinal bacterial overgrowth in irritable bowel syndrome

Shah, Ayesha, Talley, Nicholas J., Rich, Justin, Ghasemi, Pegah, Jones, Mike, Kendall, Bradley J., Burger, Daniel, Koloski, Natasha, Walker, Marjorie, Morrison, Mark and Holtmann, Gerald (2018). Systematic review and meta-analysis: Prevalence of small intestinal bacterial overgrowth in irritable bowel syndrome. Asian Pacific Digestive Week (APDW), Seoul, Korea, 15–18 November 2018. Hoboken, NJ, United States: Wiley-Blackwell.

Systematic review and meta-analysis: Prevalence of small intestinal bacterial overgrowth in irritable bowel syndrome

2018

Conference Publication

Systematic review of the use of oral antibiotic therapy in primary sclerosing cholangitis and inflammatory bowel disease

Shah, Ayesha, Burger, Daniel, Stuart, Katherine, Martin, Neal, Walker, Marjorie, Tallis, Caroline, Jones, Mike, Macdonald, Graeme, Talley, Nicholas, Morrison, Mark and Holtmann, Gerald (2018). Systematic review of the use of oral antibiotic therapy in primary sclerosing cholangitis and inflammatory bowel disease. Asian Pacific Digestive Week (APDW). Connecting Excellence on Gastroenterology and Hepatology in Asia-Pacific, Seoul, Korea, 15–18 November 2018. Richmond, VIC, Australia: Wiley-Blackwell.

Systematic review of the use of oral antibiotic therapy in primary sclerosing cholangitis and inflammatory bowel disease

2018

Conference Publication

Quantitative PCR as a novel approach to determine influence of density of bacterial colonization on health and disease

Shah, Ayesha, Shanahan, Erin, Berendsen, Erwin, Macdonald, Graeme, Rich, Justin, Ghasemi, Pegah, Hansen, Teressa, Koloski, Natasha, Burger, Daniel, Keeley, Simon, Walker, Marjorie, Talley, Nicholas, Morrison, Mark and Holtmann, Gerald (2018). Quantitative PCR as a novel approach to determine influence of density of bacterial colonization on health and disease. Asian Pacific Digestive Week (APDW). Connecting Excellence on Gastroenterology and Hepatology in Asia-Pacific, Seoul, Korea, 15–18 November 2018. Richmond, VIC, Australia: Wiley-Blackwell.

Quantitative PCR as a novel approach to determine influence of density of bacterial colonization on health and disease

2018

Conference Publication

Zonulin as a Biomarker to Identify the Irritable Bowel Syndrome (IBS), Functional Dyspepsia (FD), and Non-Celiac Wheat Sensitivity (NCWS)

Talley, Nicholas J., Holtmann, Gerald, Walker, Marjorie M., Jones, Michael, Koloski, Natasha A. and Keely, Simon (2018). Zonulin as a Biomarker to Identify the Irritable Bowel Syndrome (IBS), Functional Dyspepsia (FD), and Non-Celiac Wheat Sensitivity (NCWS). Annual Scientific Meeting of the American-College-of-Gastroenterology (ACG), Philadelphia, PA, United States, 5-10 October 2018. Philadelphia, PA, United States: Wolters Kluwer Health.

Zonulin as a Biomarker to Identify the Irritable Bowel Syndrome (IBS), Functional Dyspepsia (FD), and Non-Celiac Wheat Sensitivity (NCWS)

2018

Conference Publication

Anti-Cytolethal Distending Toxin B Antibody (Anti-CdtB) Differentiates Functional Dyspepsia From Healthy Controls

Talley, Nicholas J., Holtmann, Gerald, Walker, Marjorie M., Jones, Michael, Koloski, Natasha A. and Keely, Simon (2018). Anti-Cytolethal Distending Toxin B Antibody (Anti-CdtB) Differentiates Functional Dyspepsia From Healthy Controls. Annual Scientific Meeting of the American-College-of-Gastroenterology (ACG), Philadelphia, PA, United States, 5-10 October 2018. Philadelphia, PA, United States: Wolters Kluwer Health.

Anti-Cytolethal Distending Toxin B Antibody (Anti-CdtB) Differentiates Functional Dyspepsia From Healthy Controls

2018

Conference Publication

Quantitative polymerase chain reaction as a novel approach to determine influence of density of bacterial colonization on health and disease

Shah, A., Shanahan, E., Berendsen, E., Macdonald, G., Rich, J., Ghasemi, P., Hansen, T., Koloski, N., Burger, D., Keely, S., Walker, M., Talley, N. J., Morrison, M. and Holtmann, G. (2018). Quantitative polymerase chain reaction as a novel approach to determine influence of density of bacterial colonization on health and disease. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD Australia, 8-10 September 2018. Richmond, VIC Australia: John Wiley & Sons.

Quantitative polymerase chain reaction as a novel approach to determine influence of density of bacterial colonization on health and disease

2018

Journal Article

A novel treatment for patients with constipation: dawn of a new age for translational microbiome research?

Shah, Ayesha, Morrison, Mark and Holtmann, Gerald (2018). A novel treatment for patients with constipation: dawn of a new age for translational microbiome research?. Indian Journal of Gastroenterology, 37 (5), 388-391. doi: 10.1007/s12664-018-0912-3

A novel treatment for patients with constipation: dawn of a new age for translational microbiome research?

2018

Conference Publication

Perturbation of the gut-brain axis as the mechanism of action for weight reduction in patients treated with a duodenal-jejunal bypass sleeve

Mcmaster, J. J., Rich, G. G., Shanahan, E. R., Do, A. T., Fletcher, L. M., Kutyla, M. J., Tallis, C., Macdonald, G. A., Chachay, V. S., Morrison, M. and Holtmann, G. J. (2018). Perturbation of the gut-brain axis as the mechanism of action for weight reduction in patients treated with a duodenal-jejunal bypass sleeve. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD Australia, 8-10 September 2018. Richmond, VIC Australia: John Wiley & Sons.

Perturbation of the gut-brain axis as the mechanism of action for weight reduction in patients treated with a duodenal-jejunal bypass sleeve

2018

Journal Article

Influence of cigarette smoking on the human duodenal mucosa-associated microbiota

Shanahan, Erin R., Shah, Ayesha, Koloski, Natasha, Walker, Marjorie M., Talley, Nicholas J., Morrison, Mark and Holtmann, Gerald J. (2018). Influence of cigarette smoking on the human duodenal mucosa-associated microbiota. Microbiome, 6 (1) 150, 150. doi: 10.1186/s40168-018-0531-3

Influence of cigarette smoking on the human duodenal mucosa-associated microbiota

2018

Journal Article

Influence of simethicone added to the rinse water during colonoscopies on polyp detection rates: results of an unintended cohort study

Kutyla, Marguerite, O'Connor, Sam, Gurusamy, Saravana Ruban, Gururatsakul, Montri, Gould, Kelly, Whaley, Amanda, Kendall, Bradley J., Hourigan, Luke and Holtmann, Gerald J. (2018). Influence of simethicone added to the rinse water during colonoscopies on polyp detection rates: results of an unintended cohort study. Digestion, 98 (4), 217-221. doi: 10.1159/000489304

Influence of simethicone added to the rinse water during colonoscopies on polyp detection rates: results of an unintended cohort study

2018

Journal Article

Inconsistent symptom clusters for functional gastrointestinal disorders in Asia: is Rome burning?

Holtmann, Gerald J. and Talley, Nicholas J. (2018). Inconsistent symptom clusters for functional gastrointestinal disorders in Asia: is Rome burning?. Gut, 67 (11), 1911-1915. doi: 10.1136/gutjnl-2017-314775

Inconsistent symptom clusters for functional gastrointestinal disorders in Asia: is Rome burning?

2018

Journal Article

Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis

So, Daniel, Whelan, Kevin, Rossi, Megan, Morrison, Mark, Holtmann, Gerald, Kelly, Jaimon T., Shanahan, Erin R., Staudacher, Heidi M. and Campbell, Katrina L. (2018). Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis. The American Journal of Clinical Nutrition, 107 (6), 965-983. doi: 10.1093/ajcn/nqy041

Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis

2018

Conference Publication

Standardised oropharynx, hypopharynx and larynx assessment during 1000 consecutive elective oesophagogastroduodenosocopies - a prospective multicentre feasibility trial

Huelsen, Alexander, St John, Andrew T., Vokes, David, Hourigan, Luke F., Holtmann, Gerald and Walmsley, Russell S. (2018). Standardised oropharynx, hypopharynx and larynx assessment during 1000 consecutive elective oesophagogastroduodenosocopies - a prospective multicentre feasibility trial. Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week, Washington, DC, United States, 2-5 June 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.gie.2018.04.1864

Standardised oropharynx, hypopharynx and larynx assessment during 1000 consecutive elective oesophagogastroduodenosocopies - a prospective multicentre feasibility trial

2018

Journal Article

Opportunities of twin research in gastroenterology

Goebel-Stengel, Miriam, Holtmann, Gerald and Enck, Paul (2018). Opportunities of twin research in gastroenterology. Nature Reviews Gastroenterology and Hepatology, 15 (6), 325-326. doi: 10.1038/s41575-018-0002-0

Opportunities of twin research in gastroenterology

Funding

Current funding

  • 2022 - 2026
    ARC Training Centre for Behavioural Insights for Technology Adoption (BITA) (ARC Industrial Transformation Training Centre Administered by QUT)
    Queensland University of Technology
    Open grant
  • 2021 - 2025
    A practice change for patients with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled intervention to assess efficacy and cost-effectiveness
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2025
    Targeting the gut microbiome as a treatment for Primary Sclerosing Cholangitis: The Queensland Clinical Network Study
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant

Past funding

  • 2020 - 2024
    Modulation of the Gastrointestinal Microbiome with probiotics and subsequent Methane production as a novel approach to treat constipation: A Proof of Principle Study (TRI Sport Grant led by PAH)
    Metro South Hospital and Health Service
    Open grant
  • 2019 - 2024
    Centre for Research Excellence in Digestive Health (NHMRC CRE administered by University of Newcastle)
    University of Newcastle
    Open grant
  • 2016
    Establishing a gnotobiotic germ-free mouse facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    The Australian human microbiota project-microbe isolation facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Pathophysiology of functional dyspepsia: Integration of upper gut function, inflammation and a systems biology approach.
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy (NHMRC Project Grant administered by the University of Newcastle)
    University of Newcastle
    Open grant

Supervision

Availability

Professor Gerald Holtmann is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective.

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Equitability and Accessibility of Faecal Occult Blood Test Based Colorectal Cancer Screening for Disadvantaged Communities.

    Principal Advisor

  • Doctor Philosophy

    Reimagining Health Equity and Access in Colorectal Cancer Screening. A population perspective

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    IBD and mental health tools: a holistic approach to discovery and appropriate tool.

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Effects the COVID-19 pandemic on the outcome and management of highly prevalent gastrointestinal conditions

    Principal Advisor

    Other advisors: Dr Ayesha Shah

  • Doctor Philosophy

    Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.

    Associate Advisor

    Other advisors: Professor Jeff Coombes

  • Doctor Philosophy

    The role of the gut microbiome in alcohol related liver disease

    Associate Advisor

    Other advisors: Professor Jason Connor, Dr Paul Clark

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

  • Doctor Philosophy

    Study of TOfacitinib for the treatment of chronic Pouchitis

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun

Completed supervision

Media

Enquiries

Contact Professor Gerald Holtmann directly for media enquiries about:

  • colon cancer screening
  • Gastroenterology
  • Gut Health
  • Microbiome
  • Neurogastroenterology

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au