Overview
Availability
- Dr Paul Clark is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, The University of Queensland
- Masters (Coursework) of Public Health and Tropical Medicine, James Cook University
- Doctor of Philosophy, University of New South Wales
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Works
Search Professor Paul Clark’s works on UQ eSpace
2012
Conference Publication
Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis C
Clark, Paul J., Santoro, Rosanna, Piazzolla, Valeria, Mottola, Leonardo, Bacca, D., Dello Iacono, N., Grimaldi, Salvatore, Quarta, Antonella, Urban, Thomas J., Naggie, Susanna, Patel, Keyur, Thompson, Alexander J., Muir, Andrew J. and Mangia, Alessandra (2012). Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis C. 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Ma, Nov 09-13, 2012. HOBOKEN: WILEY-BLACKWELL.
2012
Journal Article
Systemic thrombolysis for acute, severe Budd-Chiari syndrome
Clark, P.J., Slaughter, R.E. and Radford, D.J. (2012). Systemic thrombolysis for acute, severe Budd-Chiari syndrome. Journal of Thrombosis and Thrombolysis, 34 (3), 410-415. doi: 10.1007/s11239-012-0760-4
2012
Journal Article
Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner
Clark, Paul J., Thompson, Alexander J., Vock, David M., Kratz, Lisa E., Tolun, Adviye A., Muir, Andrew J., Mchutchison, John G., Subramanian, Mani, Millington, David M., Kelley, Richard I. and Patel, Keyur (2012). Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. Hepatology, 56 (1), 49-56. doi: 10.1002/hep.25631
2012
Conference Publication
Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin Support
Clark, P. J., Aghemo, A., Degasperi, E., Galmozzi, E., Thompson, A. J., Patel, K., Rumi, M. Grazia, Prati, G. M., Muir, A. J. and Colombo, M. (2012). Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin Support. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)61111-8
2012
Conference Publication
Targeted proteomics signature identifies corticosteroid binding globulin peptides as highly predictive of treatment response in IL28B unfavorable genotype patients
Naggie, Susanna, Osinusi, Anu, Himmel, Tiffany, Lucas, Joseph, Thompson, J. W., Dubois, Laura G., Moseley, Martin A., Clark, Paul J., Kottilil, Shyam and Patel, Keyur (2012). Targeted proteomics signature identifies corticosteroid binding globulin peptides as highly predictive of treatment response in IL28B unfavorable genotype patients. 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Ma, Nov 09-13, 2012. HOBOKEN: WILEY-BLACKWELL.
2012
Journal Article
Lost in translation? IL28B's discovery and the journey back to the patient
Clark, Paul J. and Muir, Andrew J. (2012). Lost in translation? IL28B's discovery and the journey back to the patient. Hepatology, 56 (1), 5-8. doi: 10.1002/hep.25796
2012
Conference Publication
Inosine Triphosphastase (ITPA) Variants Predict Treatment-Induced Anemia, Ribavirin Dose-Reduction and Need for Erythropoietin Support During Peginterferon/Ribavirin Therapy for Chronic HCV
Clark, Paul J., Aghemo, Alessio, Degasperi, Elisabetta, Galmozzi, Enrico, Thompson, Alexander J., Patel, Keyur, Rumi, Maria Grazia, Prati, G. and Colombo, Massimo (2012). Inosine Triphosphastase (ITPA) Variants Predict Treatment-Induced Anemia, Ribavirin Dose-Reduction and Need for Erythropoietin Support During Peginterferon/Ribavirin Therapy for Chronic HCV. Digestive Disease Week (DDW), San Diego Ca, May 19-22, 2012. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2011
Journal Article
Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C
Tillmann, Hans L., Patel, Keyur, Muir, Andrew J., Guy, Cynthia D., Li, Josephine H., Lao, Xiang Qian, Thompson, Alexander, Clark, Paul J., Gardner, Stephen D., McHutchison, John G. and McCarthy, Jeanette J. (2011). Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. Journal of Hepatology, 55 (6), 1195-1200. doi: 10.1016/j.jhep.2011.03.015
2011
Journal Article
Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C
Golden-Mason, Lucy, Bambha, Kiran M., Cheng, Linling, Howell, Charles D., Taylor, Milton W., Clark, Paul J., Afdhal, Nezam and Rosen, Hugo R. (2011). Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C. Hepatology, 54 (5), 1559-1569. doi: 10.1002/hep.24556
2011
Conference Publication
PREDICTORS OF CONSENT TO PHARMACOGENOMICS TESTING IN THE IDEAL STUDY
Jazwinski, Alison, Clark, Paul J., Thompson, Alexander J., Gordon, Stuart C., Lawitz, Eric, McCone, Jonathan, Noviello, Stephanie, Brass, Clifford A., Pedicone, Lisa, Albrecht, Janice K., Sulkowski, Mark S., Muir, Andrew J. and Jazwinski, Alison (2011). PREDICTORS OF CONSENT TO PHARMACOGENOMICS TESTING IN THE IDEAL STUDY. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Journal Article
Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C
Cyr, Derek D., Lucas, Joseph E., Thompson, J. Will, Patel, Keyur, Clark, Paul J., Thompson, Alexander, Tillmann, Hans L., McHutchison, John G., Moseley, M. Arthur and McCarthy, Jeanette J. (2011). Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C. PLoS One, 6 (7) e21854, 1-6. doi: 10.1371/journal.pone.0021854
2011
Journal Article
Insulin resistance is independently associated with significant hepatic fibrosis in Asian chronic hepatitis C genotype 2 or 3 patients
Patel, Keyur, Thompson, Alexander J., Chuang, Wan-Long, Lee, Chuan-Mo, Peng, Chen-Yuan, Shanmuganathan, Ganesananthan, Thongsawat, Satawat, Tanwandee, Tawesak, Mahachai, Varocha, Pramoolsinsap, Chutima, Cho, Mong, Han, Kwang Hyup, Shah, Samir R., Foster, Graham R., Clark, Paul J., Pulkstenis, Erik, Subramanian, G. Mani and McHutchison, John G. (2011). Insulin resistance is independently associated with significant hepatic fibrosis in Asian chronic hepatitis C genotype 2 or 3 patients. Journal of Gastroenterology and Hepatology (Australia), 26 (7), 1182-1188. doi: 10.1111/j.1440-1746.2011.06722.x
2011
Conference Publication
Phosphodiesterase Polymorphisms May Be Associated with Baseline Thyroid Stimulating Hormone (Tsh) and Peginterferon Treatment Induced Hypothyroidism in Patients with Chronic Hepatitis C
Clark, P. J., Thompson, A. J., Zhu, M., Ge, D., Shianna, K., Tillmann, H. L., Patel, K., Urban, T., Singh, A., Sulkowski, M., Afdhal, N., Jacobson, I., Esteban, R., Poordad, F., Lawitz, E., McCone, J., Shiffman, M. L., Galler, G., Lee, W. M., Reindollar, R., King, J., Kwo, P., Ghalib, R., Freilich, B., Nyberg, L., Noviello, S., Bopari, N., Koury, K., Pedicone, L. D. ... Muir, A. J. (2011). Phosphodiesterase Polymorphisms May Be Associated with Baseline Thyroid Stimulating Hormone (Tsh) and Peginterferon Treatment Induced Hypothyroidism in Patients with Chronic Hepatitis C. 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Berlin Germany, 2011. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(11)60129-3
2011
Conference Publication
Metabolomic Analysis Demonstrates Hepatitis C Virus Genotypes G2/3 Selectively Perturb Distal Steps in Cholesterol Biosynthesis
Clark, Paul J., Thompson, Alexander J., Vock, David M., Kratz, Lisa E., Tolun, Adviye A., Zhang, Hao Yue, Muir, Andrew J., Subramanian, Mani, McHutchison, John G., Millington, David S., Kelley, Richard I. and Patel, Keyur (2011). Metabolomic Analysis Demonstrates Hepatitis C Virus Genotypes G2/3 Selectively Perturb Distal Steps in Cholesterol Biosynthesis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Vitamin D and Treatment Response in African American Patients with Hcv Genotype 1
Jazwinski, Alison, Clark, Paul J., Tillmann, Hans L., Muir, Andrew J. and Jazwinski, Alison (2011). Vitamin D and Treatment Response in African American Patients with Hcv Genotype 1. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Pnpla3 Genotype Rather Than Race May Explain the Lower Prevalence of Hepatic Steatosis Despite Worse Metabolic Risk Factors in African American Patients with Chronic Hepatitis C (Chc)
Clark, Paul J., Thompson, Alexander J., Urban, Thomas J., Patel, Keyur, Vock, David M., Zhu, Qianqian, Jazwinski, Alison, Naggie, Susanna, Tillmann, Hans L., McKenzie, Alexander, Conjeevaram, Hari S., Shianna, Kevin, Goldstein, David B., Afdhal, Nezam H. and Muir, Andrew J. (2011). Pnpla3 Genotype Rather Than Race May Explain the Lower Prevalence of Hepatic Steatosis Despite Worse Metabolic Risk Factors in African American Patients with Chronic Hepatitis C (Chc). 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Il28B C/c Genotype Is Predictive of >= 1 Log10 Iu/ml Reduction in Plasma Hcv Rna After 4 Weeks of Peginterferon (Pegifn) and Ribavirin (Rbv) Therapy: Implications for the Use of the Lead-In Strategy for Direct-Acting Antiviral-Based Treatment Regimens
Thompson, Alexander J., Clark, Paul J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Poordad, F. Fred, Lawitz, Eric, Bacon, Bruce R., Vierling, John M., Noviello, Stephanie, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G., Sulkowski, Mark S. and Muir, Andrew J. (2011). Il28B C/c Genotype Is Predictive of >= 1 Log10 Iu/ml Reduction in Plasma Hcv Rna After 4 Weeks of Peginterferon (Pegifn) and Ribavirin (Rbv) Therapy: Implications for the Use of the Lead-In Strategy for Direct-Acting Antiviral-Based Treatment Regimens. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
The Relationship Between Hepatic Steatosis and Il28B Response in Patients with Chronic Hepatitis C
Tillmann, H. L., Patel, K., Muir, A., Guy, C., Li, J. H., Lao, X. Q., Thompson, A. J., Clark, P. J., Gardner, S. D., McHutchison, J. G. and McCarthy, J. J. (2011). The Relationship Between Hepatic Steatosis and Il28B Response in Patients with Chronic Hepatitis C. 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Berlin Germany, 2011. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(11)61348-2
2011
Journal Article
Noninvasive tools to assess liver disease
Clark, Paul J. and Patel, Keyur (2011). Noninvasive tools to assess liver disease. Current Opinion in Gastroenterology, 27 (3), 210-216. doi: 10.1097/MOG.0b013e328343e9a3
2011
Journal Article
IL28B polymorphisms and treatment of hepatitis C
Clark, Paul J., Thompson, Alexander J. V. and Muir, Andrew J. (2011). IL28B polymorphisms and treatment of hepatitis C. Current Hepatitis Reports, 10 (1), 70-78. doi: 10.1007/s11901-010-0061-3
Funding
Current funding
Supervision
Availability
- Dr Paul Clark is:
- Available for supervision
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Available projects
-
Approaches to evaluating fibrosis and treating viral hepatitis remotely in regional Queensland
Supervision history
Current supervision
-
Doctor Philosophy
The role of the gut microbiome in alcohol related liver disease
Principal Advisor
Other advisors: Professor Jason Connor, Professor Gerald Holtmann
Completed supervision
-
2022
Doctor Philosophy
Epidemiology of viral hepatitis and liver diseases in migrant communities in Australia
Principal Advisor
Media
Enquiries
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