Overview
Availability
- Honorary Professor Paul Clark is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, The University of Queensland
- Masters (Coursework) of Public Health and Tropical Medicine, James Cook University
- Doctor of Philosophy, University of New South Wales
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Works
Search Professor Paul Clark’s works on UQ eSpace
2012
Journal Article
Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response
Clark, P. J., Thompson, A. J., Zhu, M., Vock, D. M., Zhu, Q., Ge, D., Patel, K., Harrison, S. A., Urban, T. J., Naggie, S., Fellay, J., Tillmann, H. L., Shianna, K., Noviello, S., Pedicone, L. D., Esteban, R., Kwo, P., Sulkowski, M. S., Afdhal, N., Albrecht, J. K., Goldstein, D. B., McHutchison, J. G. and Muir, A. J. (2012). Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. Journal of Viral Hepatitis, 19 (5), 332-340. doi: 10.1111/j.1365-2893.2011.01553.x
2012
Conference Publication
Association of Serum Adipocytokines With IL28B and SVR in Chronic Hepatitis C
Clark, Paul J., Thompson, Alexander J., Jazwinski, Alison, Tillmann, Hans L., Naggie, Susanna, Muir, Andrew J. and Patel, Keyur (2012). Association of Serum Adipocytokines With IL28B and SVR in Chronic Hepatitis C. Digestive Disease Week (DDW), San Diego Ca, May 19-22, 2012. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2012
Journal Article
Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis
Jazwinski, A. B., Thompson, A. J., Clark, P. J., Naggie, S., Tillmann, H. L. and Patel, K. (2012). Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis. Journal of Viral Hepatitis, 19 (4), 278-282. doi: 10.1111/j.1365-2893.2011.01546.x
2012
Journal Article
Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?"
Thompson, A. J., Clark, P. J., Muir, A. J. and Sulkowski, M. S. (2012). Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?". Journal of Hepatology, 56 (3), 742-743. doi: 10.1016/j.jhep.2011.08.011
2012
Journal Article
Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients
Thompson, Alexander J., Clark, Paul J., Singh, Abanish, Ge, Dongliang, Fellay, Jacques, Zhu, Mingfu, Zhu, Qianqian, Urban, Thomas J., Patel, Keyur, Tillmann, Hans L., Naggie, Susanna, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric J., McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg W., King, John W., Kwo, Paul Y., Shianna, Kevin V., Noviello, Stephanie, Pedicone, Lisa D., Brass, Clifford A., Albrecht, Janice K., Sulkowski, Mark S., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. Journal of Hepatology, 56 (2), 313-319. doi: 10.1016/j.jhep.2011.04.021
2012
Journal Article
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes
Naggie, Susanna, Rallon, Norma I., Benito, Jose M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin V., Vispo, Eugenia, McHutchison, John G., Goldstein, David B. and Soriano, Vincent (2012). Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes. Journal of Infectious Diseases, 205 (3), 376-383. doi: 10.1093/infdis/jir754
2012
Conference Publication
Targeted proteomics signature identifies corticosteroid binding globulin peptides as highly predictive of treatment response in IL28B unfavorable genotype patients
Naggie, Susanna, Osinusi, Anu, Himmel, Tiffany, Lucas, Joseph, Thompson, J. W., Dubois, Laura G., Moseley, Martin A., Clark, Paul J., Kottilil, Shyam and Patel, Keyur (2012). Targeted proteomics signature identifies corticosteroid binding globulin peptides as highly predictive of treatment response in IL28B unfavorable genotype patients. 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Ma, Nov 09-13, 2012. HOBOKEN: WILEY-BLACKWELL.
2012
Journal Article
Lost in translation? IL28B's discovery and the journey back to the patient
Clark, Paul J. and Muir, Andrew J. (2012). Lost in translation? IL28B's discovery and the journey back to the patient. Hepatology, 56 (1), 5-8. doi: 10.1002/hep.25796
2012
Conference Publication
Inosine Triphosphastase (ITPA) Variants Predict Treatment-Induced Anemia, Ribavirin Dose-Reduction and Need for Erythropoietin Support During Peginterferon/Ribavirin Therapy for Chronic HCV
Clark, Paul J., Aghemo, Alessio, Degasperi, Elisabetta, Galmozzi, Enrico, Thompson, Alexander J., Patel, Keyur, Rumi, Maria Grazia, Prati, G. and Colombo, Massimo (2012). Inosine Triphosphastase (ITPA) Variants Predict Treatment-Induced Anemia, Ribavirin Dose-Reduction and Need for Erythropoietin Support During Peginterferon/Ribavirin Therapy for Chronic HCV. Digestive Disease Week (DDW), San Diego Ca, May 19-22, 2012. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2012
Journal Article
Host genomics and HCV treatment response
Clark, Paul J. and Thompson, Alexander J. (2012). Host genomics and HCV treatment response. Journal of Gastroenterology and Hepatology, 27 (2), 212-222. doi: 10.1111/j.1440-1746.2011.06918.x
2012
Conference Publication
Analysis of Genotype 1 Hcv Adaptation to Host Il28B Polymorphism - Evidence for Viral Innate Immune Escape Patterns
Thompson, A. J., Clark, P. J., Patel, K., Tillmann, H. L., Urban, T. J., Shianna, K. V., Goldstein, D. B., McHutchison, J. G., Muir, A. J., James, I., Lucas, M. and Gaudieri, S. (2012). Analysis of Genotype 1 Hcv Adaptation to Host Il28B Polymorphism - Evidence for Viral Innate Immune Escape Patterns. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)60942-8
2012
Conference Publication
MRECIST Criteria Response to Pretransplant Transarterial Chemoembolization (TACE) is Predictive of Improved Survival for Patients With HCV Undergoing Liver Transplantation for Hepatocellular Carcinoma (HCC)
Clark, Paul J., Heimbach, Julie K., Rosen, Charles B., Sanchez, William, Gores, Gregory J., Muir, Andrew J. and Charlton, Michael R. (2012). MRECIST Criteria Response to Pretransplant Transarterial Chemoembolization (TACE) is Predictive of Improved Survival for Patients With HCV Undergoing Liver Transplantation for Hepatocellular Carcinoma (HCC). Digestive Disease Week (DDW), San Diego Ca, May 19-22, 2012. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2012
Conference Publication
Exploration of Serum Adipocytokine Associations with Il28B Genotype in Chronic Hepatitis C
Clark, P. J., Thompson, A. J., Tillmann, H. L., Jazwinski, A., Naggie, S., Muir, A. J. and Patel, K. (2012). Exploration of Serum Adipocytokine Associations with Il28B Genotype in Chronic Hepatitis C. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)60896-4
2012
Journal Article
The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection
Clark, Paul J., Thompson, Alexander J., Zhu, Qianqian, Vock, David M., Zhu, Mingfu, Patel, Keyur, Harrison, Stephen A., Naggie, Susanna, Ge, Dongliang, Tillmann, Hans L., Urban, Thomas J., Shianna, Kevin, Fellay, Jacques, Goodman, Zachary, Noviello, Stephanie, Pedicone, Lisa D., Afdhal, Nezam, Sulkowski, Mark, Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection. Digestive Diseases and Sciences, 57 (8), 2213-2221. doi: 10.1007/s10620-012-2171-y
2012
Conference Publication
Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis C
Clark, Paul J., Santoro, Rosanna, Piazzolla, Valeria, Mottola, Leonardo, Bacca, D., Dello Iacono, N., Grimaldi, Salvatore, Quarta, Antonella, Urban, Thomas J., Naggie, Susanna, Patel, Keyur, Thompson, Alexander J., Muir, Andrew J. and Mangia, Alessandra (2012). Optimizing ribavirin dose is critical for sustained viral response in patients with thalassemia major treated for chronic hepatitis C. 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Ma, Nov 09-13, 2012. HOBOKEN: WILEY-BLACKWELL.
2012
Journal Article
Systemic thrombolysis for acute, severe Budd-Chiari syndrome
Clark, P.J., Slaughter, R.E. and Radford, D.J. (2012). Systemic thrombolysis for acute, severe Budd-Chiari syndrome. Journal of Thrombosis and Thrombolysis, 34 (3), 410-415. doi: 10.1007/s11239-012-0760-4
2012
Journal Article
Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner
Clark, Paul J., Thompson, Alexander J., Vock, David M., Kratz, Lisa E., Tolun, Adviye A., Muir, Andrew J., Mchutchison, John G., Subramanian, Mani, Millington, David M., Kelley, Richard I. and Patel, Keyur (2012). Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. Hepatology, 56 (1), 49-56. doi: 10.1002/hep.25631
2012
Conference Publication
Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin Support
Clark, P. J., Aghemo, A., Degasperi, E., Galmozzi, E., Thompson, A. J., Patel, K., Rumi, M. Grazia, Prati, G. M., Muir, A. J. and Colombo, M. (2012). Itpa Variants Predict Treatment-Induced Anemia and the Need for Ribavirin Dose Reduction and Erythropoietin Support. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)61111-8
2011
Journal Article
Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C
Tillmann, Hans L., Patel, Keyur, Muir, Andrew J., Guy, Cynthia D., Li, Josephine H., Lao, Xiang Qian, Thompson, Alexander, Clark, Paul J., Gardner, Stephen D., McHutchison, John G. and McCarthy, Jeanette J. (2011). Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. Journal of Hepatology, 55 (6), 1195-1200. doi: 10.1016/j.jhep.2011.03.015
2011
Journal Article
Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C
Golden-Mason, Lucy, Bambha, Kiran M., Cheng, Linling, Howell, Charles D., Taylor, Milton W., Clark, Paul J., Afdhal, Nezam and Rosen, Hugo R. (2011). Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C. Hepatology, 54 (5), 1559-1569. doi: 10.1002/hep.24556
Funding
Past funding
Supervision
Availability
- Honorary Professor Paul Clark is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
-
Approaches to evaluating fibrosis and treating viral hepatitis remotely in regional Queensland
Supervision history
Current supervision
-
Doctor Philosophy
The role of the gut microbiome in alcohol related liver disease
Principal Advisor
Other advisors: Professor Jason Connor, Professor Gerald Holtmann
Completed supervision
-
2022
Doctor Philosophy
Epidemiology of viral hepatitis and liver diseases in migrant communities in Australia
Principal Advisor
Media
Enquiries
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