Overview
Availability
- Dr Paul Clark is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, The University of Queensland
- Masters (Coursework) of Public Health and Tropical Medicine, James Cook University
- Doctor of Philosophy, University of New South Wales
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Works
Search Professor Paul Clark’s works on UQ eSpace
2011
Journal Article
IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: The future of personalized HCV therapies
Clark, Paul J., Thompson, Alex J. and McHutchison, John G. (2011). IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: The future of personalized HCV therapies. American Journal of Gastroenterology, 106 (1), 38-45. doi: 10.1038/ajg.2010.370
2011
Conference Publication
PREDICTING PEGINTERFERON-alpha AND RIBAVIRIN TREATMENT RESPONSE IN GENOTYPE 1 HCV PATIENTS - SIMPLE NOMOGRAMS TO SUPPORT CLINICIANS
Thompson, Alexander J., Clark, Paul J., Vock, David M., Pfeiffer, Ruth, Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Poordad, F. Fred, Nyberg, Lisa M., Noviello, Stephanie, Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G., O'Brien, Thomas R., Sulkowski, Mark S. and Muir, Andrew J. (2011). PREDICTING PEGINTERFERON-alpha AND RIBAVIRIN TREATMENT RESPONSE IN GENOTYPE 1 HCV PATIENTS - SIMPLE NOMOGRAMS TO SUPPORT CLINICIANS. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Thyroid Stimulating Hormone (TSH) and Peginterferon Treatment Induced Hypothyroidism May Be Associated With Phosphodiesterase Polymorphisms in Patients With Chronic Hepatitis C
Clark, Paul, Thompson, Alexander J., Zhu, Mingfu, Ge, Dongliang, Shianna, Kevin, Tillmann, Hans L., Patel, Keyur, Urban, Thomas, Singh, Abanish, Sulkowski, Mark, Afdhal, Nezam, Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric J., McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg, Lee, William M., Reindollar, Robert W., King, John W., Kwo, Paul Y., Ghalib, Reem H., Freilich, Bradley, Nyberg, Lisa M., Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth, Pedicone, Lisa D. and Brass, Clifford A. (2011). Thyroid Stimulating Hormone (TSH) and Peginterferon Treatment Induced Hypothyroidism May Be Associated With Phosphodiesterase Polymorphisms in Patients With Chronic Hepatitis C. Conference on Digestive Disease Week 2011, Chicago Il, May 07-10, 2011. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2011
Conference Publication
Nk Inhibitory Receptor Expression Associated with Treatment Failure and Il-28B Genotype in Patients with Chronic Hepatitis C
Golden-Mason, Lucy, Bambha, Kiran, Cheng, Linling, Howell, Charles D., Taylor, Milton W., Clark, Paul J., Afdhal, Nezam H. and Rosen, Hugo R. (2011). Nk Inhibitory Receptor Expression Associated with Treatment Failure and Il-28B Genotype in Patients with Chronic Hepatitis C. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Journal Article
Inosine triphosphatase genetic variants are protective against anemia during antiviral therapy for HCV2/3 but do not decrease dose reductions of RBV or increase SVR
Thompson, Alexander J., Santoro, Rosanna, Piazzolla, Valeria, Clark, Paul J., Naggie, Susanna, Tillmann, Hans L., Patel, Keyur, Muir, Andrew J., Shianna, Kevin V., Mottola, Leonardo, Petruzzellis, Daniela, Romano, Mario, Sogari, Fernando, Facciorusso, Domenico, Goldstein, David B., McHutchison, John G. and Mangia, Alessandra (2011). Inosine triphosphatase genetic variants are protective against anemia during antiviral therapy for HCV2/3 but do not decrease dose reductions of RBV or increase SVR. Hepatology, 53 (2), 389-395. doi: 10.1002/hep.24068
2011
Conference Publication
Dysregulation of Host Innate Immunity in Hcv Genotype 1 Infected Il28B Ct/tt Haplotype Patients with Depressed Viral Kinetics and Therapeutic Response
Naggie, S., Osinusi, A., Katsounas, A., Lempicki, R., Herrmann, E., Shivakumar, B., Thompson, A., Clark, P., Patel, K., Muir, A., Mchutchison, J., Goldstein, D., Schlaak, J., Masur, H., Polis, M. and Kottilil, S. (2011). Dysregulation of Host Innate Immunity in Hcv Genotype 1 Infected Il28B Ct/tt Haplotype Patients with Depressed Viral Kinetics and Therapeutic Response. 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Berlin Germany, 2011. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(11)61336-6
2011
Conference Publication
The Cost-Effectiveness of a Telaprevir-Inclusive Regimen as Initial Therapy for Genotype 1 Hepatitis C Infection in Individuals with the Cc Il-28B Polymorphism
Gellad, Ziad F., Naggie, Susanna, Reed, Shelby D., Clark, Paul J., Thompson, Alex J., Schulman, Kevin A. and Muir, Andrew J. (2011). The Cost-Effectiveness of a Telaprevir-Inclusive Regimen as Initial Therapy for Genotype 1 Hepatitis C Infection in Individuals with the Cc Il-28B Polymorphism. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2010
Journal Article
Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotype
Thomison, Allxander J., Muir, Andrew J., Sulkowski, Mark. S., Path, Keyur, Jilimann, Hans L., Clark, Paul J., Naccie, Susanna, Fellay, Jacques, Ge, Dongliang, McCarthy, Jlanlite J., Goldslin, David B. and McHutchison, John G. (2010). Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotype. Hepatology, 52 (6), 2243-2244. doi: 10.1002/hep.23826
2010
Conference Publication
Variants in the Itpa Gene Protect Against Early Ribavirin-Induced Hemolytic Anemia in Hiv/hcv Co-Infected Patients
Naggie, Susanna, Rallon, Norma I., Benito, Jose M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin, Vispo, Eugenia, McHutchison, John G., Goldstein, David B. and Soriano, Vincent (2010). Variants in the Itpa Gene Protect Against Early Ribavirin-Induced Hemolytic Anemia in Hiv/hcv Co-Infected Patients. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Journal Article
Hepatitis C virus nonstructural protein 5A inhibitors: Novel target - Now for new trials and new treatment strategies
Thompson, Alex J., Clark, Paul J. and McHutchison, John G. (2010). Hepatitis C virus nonstructural protein 5A inhibitors: Novel target - Now for new trials and new treatment strategies. Hepatology, 52 (3), 1162-1164. doi: 10.1002/hep.23853
2010
Journal Article
The diagnosis and management of hereditary haemochromatosis
Clark, Paul, Britton, Laurence J. and Powell, Lawrie W. (2010). The diagnosis and management of hereditary haemochromatosis. Clinical Biochemist Reviews, 31 (1), 3-8.
2010
Conference Publication
Itpa Genetic Variants Are Protective Against Anemia During Antiviral Therapy for G2/3 Hcv, But Do Not Decrease the Need for Rbv Dose Reduction or Increase Svr
Thompson, Alexander J., Santoro, Rosanna, Piazzolla, Valeria, Tillman, Hans L., Patel, Keyur, Clark, Paul J., Naggie, Susanna, Shianna, Kevin, Mottola, Leonardo, Petruzzellis, Daniela, Romano, Mario, Sogari, Fernando, Facciorusso, Domenico, Goldstein, David B., McHutchison, John G. and Mangia, Alessandra (2010). Itpa Genetic Variants Are Protective Against Anemia During Antiviral Therapy for G2/3 Hcv, But Do Not Decrease the Need for Rbv Dose Reduction or Increase Svr. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Genome Wide-Association Study Identifies Il28B Polymorphism to Be Associated with Baseline Alt and Hepatic Necro-Inflammatory Activity in Chronic Hepatitis C Patients Enrolled in the Ideal Study
Thompson, Alexander J., Clark, Paul J., Zhu, Mingfu, Zhu, Qianqian, Ge, Dongliang, Sulkowski, Mark S., Muir, Andrew J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Afdhal, Nezam H., Jacobsons, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa Marie, Goodman, Zachary, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford, Albrecht, Janice K., Goldstein, David B. and McHutchison, John G. (2010). Genome Wide-Association Study Identifies Il28B Polymorphism to Be Associated with Baseline Alt and Hepatic Necro-Inflammatory Activity in Chronic Hepatitis C Patients Enrolled in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Il28B Genotype Is Not Associated with Advanced Hepatic Fibrosis in Chronic Hepatitis C Patients Enrolled in the Ideal Study
Thompson, Alexander J., Clark, Paul J., Fellay, Jacques, Muir, Andrew J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa M., Goodman, Zachary, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Sulkowski, Mark S. (2010). Il28B Genotype Is Not Associated with Advanced Hepatic Fibrosis in Chronic Hepatitis C Patients Enrolled in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Clinical and Histological Predictors of Discordance Between the Fibrotest and Fibroscan: Analysis of the Achieve Cohorts
Clark, Paul J., Thompson, Alexander J., Tillmann, Hans L., Torbenson, Michael, Pulkstenis, Erik, Subramanian, Mani, McHutchison, John G. and Patel, Keyur (2010). Clinical and Histological Predictors of Discordance Between the Fibrotest and Fibroscan: Analysis of the Achieve Cohorts. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
HEPATITIS C TRIALS THAT COMBINE INVESTIGATIONAL AGENTS WITH PEGYLATED-INTERFERON-alpha SHOULD BE STRATIFIED BY IL28B GENOTYPE
Thompson, Alexander J., Muir, Andrew J., Sulkowski, Mark S., Patel, Keyur, Tillmann, Hans L., Clark, Paul J., Naggie, Susanna, Fellay, Jacques, Ge, Dongliang, McCarthy, Jeanette, Goldstein, David B. and McHutchison, John G. (2010). HEPATITIS C TRIALS THAT COMBINE INVESTIGATIONAL AGENTS WITH PEGYLATED-INTERFERON-alpha SHOULD BE STRATIFIED BY IL28B GENOTYPE. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Independent Validation of the Safe Biopsy Algorithm: Analysis of the Achieve Cohorts
Thompson, A., Clark, P., Tillmann, H., Torbenson, M., Pulkstenis, E., Subramanian, G. M., McHutchison, J. and Patel, K. (2010). Independent Validation of the Safe Biopsy Algorithm: Analysis of the Achieve Cohorts. 45th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Vienna Austria, Apr 14-18, 2010. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(10)61085-9
2010
Journal Article
Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection
Clark, P. J., Thompson, A. J. V. and McHutchison, J. G. (2010). Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection. Clinical Pharmacology and Therapeutics, 88 (5), 708-711. doi: 10.1038/clpt.2010.185
2010
Conference Publication
Common Genetic Variants Do Not Associate with Ifn-Induced Neutropenia in a Genome-Wide Association Study of Chronic Hepatitis C Patients in the Ideal Study
Thompson, Alexander J., Clark, Paul J., Singh, Abanish, Ge, Dongliang, Fellay, Jacques, Sulkowski, Mark S., Muir, Andrew J., Tillman, Hans L., Patel, Keyur, Naggie, Susanna, Shianna, Kevin, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B. and McHutchison, John G. (2010). Common Genetic Variants Do Not Associate with Ifn-Induced Neutropenia in a Genome-Wide Association Study of Chronic Hepatitis C Patients in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Il28B Genetic Polymorphism Has Genome Wide Significant Associations with Serum Low Density Lipoprotein Levels and Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C (Chc)
Clark, Paul J., Thompson, Alexander J., Zhu, Mingfu, Zhu, Qianqian, Ge, Dongliang, Sulkowski, Mark S., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Muir, Andrew J., Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Lawitz, Eric, Poordad, Fred, Shiffman, Mitchell L., Galler, Greg Wayne, Harrison, Stephen, King, John W., Kwo, Paul Y., Nyberg, Lisa M., McCone, Jonathan, Lee, William M., Reindollar, Robert, Ghalib, Reem H., Freilich, Bradley, Goodman, Zachary, Boparai, Navdeep, Koury, Kenneth J. ... McHutchison, John G. (2010). Il28B Genetic Polymorphism Has Genome Wide Significant Associations with Serum Low Density Lipoprotein Levels and Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C (Chc). 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
Funding
Current funding
Supervision
Availability
- Dr Paul Clark is:
- Available for supervision
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Available projects
-
Approaches to evaluating fibrosis and treating viral hepatitis remotely in regional Queensland
Supervision history
Current supervision
-
Doctor Philosophy
The role of the gut microbiome in alcohol related liver disease
Principal Advisor
Other advisors: Professor Jason Connor, Professor Gerald Holtmann
Completed supervision
-
2022
Doctor Philosophy
Epidemiology of viral hepatitis and liver diseases in migrant communities in Australia
Principal Advisor
Media
Enquiries
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