Overview
Availability
- Dr Paul Clark is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, The University of Queensland
- Masters (Coursework) of Public Health and Tropical Medicine, James Cook University
- Doctor of Philosophy, University of New South Wales
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Works
Search Professor Paul Clark’s works on UQ eSpace
2011
Conference Publication
The Cost-Effectiveness of a Telaprevir-Inclusive Regimen as Initial Therapy for Genotype 1 Hepatitis C Infection in Individuals with the Cc Il-28B Polymorphism
Gellad, Ziad F., Naggie, Susanna, Reed, Shelby D., Clark, Paul J., Thompson, Alex J., Schulman, Kevin A. and Muir, Andrew J. (2011). The Cost-Effectiveness of a Telaprevir-Inclusive Regimen as Initial Therapy for Genotype 1 Hepatitis C Infection in Individuals with the Cc Il-28B Polymorphism. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Metabolomic Analysis Demonstrates Hepatitis C Virus Genotypes G2/3 Selectively Perturb Distal Steps in Cholesterol Biosynthesis
Clark, Paul J., Thompson, Alexander J., Vock, David M., Kratz, Lisa E., Tolun, Adviye A., Zhang, Hao Yue, Muir, Andrew J., Subramanian, Mani, McHutchison, John G., Millington, David S., Kelley, Richard I. and Patel, Keyur (2011). Metabolomic Analysis Demonstrates Hepatitis C Virus Genotypes G2/3 Selectively Perturb Distal Steps in Cholesterol Biosynthesis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Vitamin D and Treatment Response in African American Patients with Hcv Genotype 1
Jazwinski, Alison, Clark, Paul J., Tillmann, Hans L., Muir, Andrew J. and Jazwinski, Alison (2011). Vitamin D and Treatment Response in African American Patients with Hcv Genotype 1. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Pnpla3 Genotype Rather Than Race May Explain the Lower Prevalence of Hepatic Steatosis Despite Worse Metabolic Risk Factors in African American Patients with Chronic Hepatitis C (Chc)
Clark, Paul J., Thompson, Alexander J., Urban, Thomas J., Patel, Keyur, Vock, David M., Zhu, Qianqian, Jazwinski, Alison, Naggie, Susanna, Tillmann, Hans L., McKenzie, Alexander, Conjeevaram, Hari S., Shianna, Kevin, Goldstein, David B., Afdhal, Nezam H. and Muir, Andrew J. (2011). Pnpla3 Genotype Rather Than Race May Explain the Lower Prevalence of Hepatic Steatosis Despite Worse Metabolic Risk Factors in African American Patients with Chronic Hepatitis C (Chc). 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Journal Article
Noninvasive tools to assess liver disease
Clark, Paul J. and Patel, Keyur (2011). Noninvasive tools to assess liver disease. Current Opinion in Gastroenterology, 27 (3), 210-216. doi: 10.1097/MOG.0b013e328343e9a3
2011
Conference Publication
Il28B C/c Genotype Is Predictive of >= 1 Log10 Iu/ml Reduction in Plasma Hcv Rna After 4 Weeks of Peginterferon (Pegifn) and Ribavirin (Rbv) Therapy: Implications for the Use of the Lead-In Strategy for Direct-Acting Antiviral-Based Treatment Regimens
Thompson, Alexander J., Clark, Paul J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Poordad, F. Fred, Lawitz, Eric, Bacon, Bruce R., Vierling, John M., Noviello, Stephanie, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G., Sulkowski, Mark S. and Muir, Andrew J. (2011). Il28B C/c Genotype Is Predictive of >= 1 Log10 Iu/ml Reduction in Plasma Hcv Rna After 4 Weeks of Peginterferon (Pegifn) and Ribavirin (Rbv) Therapy: Implications for the Use of the Lead-In Strategy for Direct-Acting Antiviral-Based Treatment Regimens. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
The Relationship Between Hepatic Steatosis and Il28B Response in Patients with Chronic Hepatitis C
Tillmann, H. L., Patel, K., Muir, A., Guy, C., Li, J. H., Lao, X. Q., Thompson, A. J., Clark, P. J., Gardner, S. D., McHutchison, J. G. and McCarthy, J. J. (2011). The Relationship Between Hepatic Steatosis and Il28B Response in Patients with Chronic Hepatitis C. 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Berlin Germany, 2011. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(11)61348-2
2011
Journal Article
IL28B polymorphisms and treatment of hepatitis C
Clark, Paul J., Thompson, Alexander J. V. and Muir, Andrew J. (2011). IL28B polymorphisms and treatment of hepatitis C. Current Hepatitis Reports, 10 (1), 70-78. doi: 10.1007/s11901-010-0061-3
2011
Journal Article
IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: The future of personalized HCV therapies
Clark, Paul J., Thompson, Alex J. and McHutchison, John G. (2011). IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: The future of personalized HCV therapies. American Journal of Gastroenterology, 106 (1), 38-45. doi: 10.1038/ajg.2010.370
2011
Conference Publication
PREDICTING PEGINTERFERON-alpha AND RIBAVIRIN TREATMENT RESPONSE IN GENOTYPE 1 HCV PATIENTS - SIMPLE NOMOGRAMS TO SUPPORT CLINICIANS
Thompson, Alexander J., Clark, Paul J., Vock, David M., Pfeiffer, Ruth, Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Poordad, F. Fred, Nyberg, Lisa M., Noviello, Stephanie, Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G., O'Brien, Thomas R., Sulkowski, Mark S. and Muir, Andrew J. (2011). PREDICTING PEGINTERFERON-alpha AND RIBAVIRIN TREATMENT RESPONSE IN GENOTYPE 1 HCV PATIENTS - SIMPLE NOMOGRAMS TO SUPPORT CLINICIANS. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
Thyroid Stimulating Hormone (TSH) and Peginterferon Treatment Induced Hypothyroidism May Be Associated With Phosphodiesterase Polymorphisms in Patients With Chronic Hepatitis C
Clark, Paul, Thompson, Alexander J., Zhu, Mingfu, Ge, Dongliang, Shianna, Kevin, Tillmann, Hans L., Patel, Keyur, Urban, Thomas, Singh, Abanish, Sulkowski, Mark, Afdhal, Nezam, Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric J., McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg, Lee, William M., Reindollar, Robert W., King, John W., Kwo, Paul Y., Ghalib, Reem H., Freilich, Bradley, Nyberg, Lisa M., Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth, Pedicone, Lisa D. and Brass, Clifford A. (2011). Thyroid Stimulating Hormone (TSH) and Peginterferon Treatment Induced Hypothyroidism May Be Associated With Phosphodiesterase Polymorphisms in Patients With Chronic Hepatitis C. Conference on Digestive Disease Week 2011, Chicago Il, May 07-10, 2011. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC.
2010
Journal Article
Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotype
Thomison, Allxander J., Muir, Andrew J., Sulkowski, Mark. S., Path, Keyur, Jilimann, Hans L., Clark, Paul J., Naccie, Susanna, Fellay, Jacques, Ge, Dongliang, McCarthy, Jlanlite J., Goldslin, David B. and McHutchison, John G. (2010). Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotype. Hepatology, 52 (6), 2243-2244. doi: 10.1002/hep.23826
2010
Conference Publication
Variants in the Itpa Gene Protect Against Early Ribavirin-Induced Hemolytic Anemia in Hiv/hcv Co-Infected Patients
Naggie, Susanna, Rallon, Norma I., Benito, Jose M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin, Vispo, Eugenia, McHutchison, John G., Goldstein, David B. and Soriano, Vincent (2010). Variants in the Itpa Gene Protect Against Early Ribavirin-Induced Hemolytic Anemia in Hiv/hcv Co-Infected Patients. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Journal Article
Hepatitis C virus nonstructural protein 5A inhibitors: Novel target - Now for new trials and new treatment strategies
Thompson, Alex J., Clark, Paul J. and McHutchison, John G. (2010). Hepatitis C virus nonstructural protein 5A inhibitors: Novel target - Now for new trials and new treatment strategies. Hepatology, 52 (3), 1162-1164. doi: 10.1002/hep.23853
2010
Journal Article
The diagnosis and management of hereditary haemochromatosis
Clark, Paul, Britton, Laurence J. and Powell, Lawrie W. (2010). The diagnosis and management of hereditary haemochromatosis. Clinical Biochemist Reviews, 31 (1), 3-8.
2010
Journal Article
Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection
Clark, P. J., Thompson, A. J. V. and McHutchison, J. G. (2010). Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection. Clinical Pharmacology and Therapeutics, 88 (5), 708-711. doi: 10.1038/clpt.2010.185
2010
Conference Publication
Common Genetic Variants Do Not Associate with Ifn-Induced Neutropenia in a Genome-Wide Association Study of Chronic Hepatitis C Patients in the Ideal Study
Thompson, Alexander J., Clark, Paul J., Singh, Abanish, Ge, Dongliang, Fellay, Jacques, Sulkowski, Mark S., Muir, Andrew J., Tillman, Hans L., Patel, Keyur, Naggie, Susanna, Shianna, Kevin, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B. and McHutchison, John G. (2010). Common Genetic Variants Do Not Associate with Ifn-Induced Neutropenia in a Genome-Wide Association Study of Chronic Hepatitis C Patients in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Il28B Genetic Polymorphism Has Genome Wide Significant Associations with Serum Low Density Lipoprotein Levels and Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C (Chc)
Clark, Paul J., Thompson, Alexander J., Zhu, Mingfu, Zhu, Qianqian, Ge, Dongliang, Sulkowski, Mark S., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Muir, Andrew J., Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Lawitz, Eric, Poordad, Fred, Shiffman, Mitchell L., Galler, Greg Wayne, Harrison, Stephen, King, John W., Kwo, Paul Y., Nyberg, Lisa M., McCone, Jonathan, Lee, William M., Reindollar, Robert, Ghalib, Reem H., Freilich, Bradley, Goodman, Zachary, Boparai, Navdeep, Koury, Kenneth J. ... McHutchison, John G. (2010). Il28B Genetic Polymorphism Has Genome Wide Significant Associations with Serum Low Density Lipoprotein Levels and Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C (Chc). 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Itpa Genetic Variants Are Protective Against Anemia During Antiviral Therapy for G2/3 Hcv, But Do Not Decrease the Need for Rbv Dose Reduction or Increase Svr
Thompson, Alexander J., Santoro, Rosanna, Piazzolla, Valeria, Tillman, Hans L., Patel, Keyur, Clark, Paul J., Naggie, Susanna, Shianna, Kevin, Mottola, Leonardo, Petruzzellis, Daniela, Romano, Mario, Sogari, Fernando, Facciorusso, Domenico, Goldstein, David B., McHutchison, John G. and Mangia, Alessandra (2010). Itpa Genetic Variants Are Protective Against Anemia During Antiviral Therapy for G2/3 Hcv, But Do Not Decrease the Need for Rbv Dose Reduction or Increase Svr. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
2010
Conference Publication
Genome Wide-Association Study Identifies Il28B Polymorphism to Be Associated with Baseline Alt and Hepatic Necro-Inflammatory Activity in Chronic Hepatitis C Patients Enrolled in the Ideal Study
Thompson, Alexander J., Clark, Paul J., Zhu, Mingfu, Zhu, Qianqian, Ge, Dongliang, Sulkowski, Mark S., Muir, Andrew J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Afdhal, Nezam H., Jacobsons, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa Marie, Goodman, Zachary, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford, Albrecht, Janice K., Goldstein, David B. and McHutchison, John G. (2010). Genome Wide-Association Study Identifies Il28B Polymorphism to Be Associated with Baseline Alt and Hepatic Necro-Inflammatory Activity in Chronic Hepatitis C Patients Enrolled in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL.
Funding
Current funding
Supervision
Availability
- Dr Paul Clark is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
-
Approaches to evaluating fibrosis and treating viral hepatitis remotely in regional Queensland
Supervision history
Current supervision
-
Doctor Philosophy
The role of the gut microbiome in alcohol related liver disease
Principal Advisor
Other advisors: Professor Jason Connor, Professor Gerald Holtmann
Completed supervision
-
2022
Doctor Philosophy
Epidemiology of viral hepatitis and liver diseases in migrant communities in Australia
Principal Advisor
Media
Enquiries
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